Module number 1285




Database revision : gnsdb28.10
Date : Tue Feb 25 17:05:40 2003
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mHST2:Homolog of SIR2,,\n mKRE23:Killer toxin REsistant,,Null mutant is K1 killer toxin resis\ntent\n Cond287:2-deoxy-D-glucose\n Cond273:yor078w\n Cond101:mrpl33\n mNOP1:nucleolar protein, homologous to mammalian fibrillarin,nucle\nolar protein , similar to mammalian fibrillarin,Null mutant \nis inviable. Temperature-sensitive alleles exhibit various d\nefects in rRNA processing.\n Cond292:Glucosamine\n Cond102:mrt4\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n mMSL5:branchpoint bridging protein -- component of the splicing co\nmmitment complex,,\n Cond248:ymr030w\n Cond278:CDC42(tetpromoter)\n mHCR1:High Copy suppressor of RPG1,,viable\n Cond130:rml2(**13)\n mPMT2:Transfers mannosyl residues from dolichyl phosphate-D-mannos\ne to seryl and threonyl residues in proteins; acts in comple\nx with Pmt1p,dolichyl phosphate-D-mannose:protein O-D-mannos\nyltransferase,Null mutants are viable but show diminished in\n vitro and in vivo O-mannosylation activity; pmt1 pmt2 doubl\ne mutant shows severe growth defect but has residual O-manno\nsylation activity; pmt2 pmt3 pmt4 triple mutant is inviable\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mSOL2:multicopy suppressor of los1-1,,Null mutant is viable\n mPMI40:catalyzes the interconversion of fructose-6-P and mannose-6-\nP,mannose-6-phosphate isomerase,Null mutant requires D-manno\nse for growth; temperature-sensitive mutant, in the absence \nof exogenous D-mannose, is unable to synthesize GDP-mannose \nand dolichol-phosphate-mannose and is unable to secrete some\n cell wall-associated proteins at the restrictive temperatur\ne\n Cond134:rpl12a\n Cond58:erp2\n Cond170:ste20(**11)\n Cond256:ymr141c\n Cond52:erd1\n Cond280:FKS1(tetpromoter)\n Cond26:cka2\n Cond185:ubr2\n mYJR116W:Unknown ,, Unknown\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond140:rps24a(**9)\n Cond105:nrf1\n mENO2:enolase,enolase,Null mutant is inviable\n Cond15:bim1(**15)\n Cond205:yel033w\n Cond284:PMA1(tetpromoter)\n mCYS3:cystathionine gamma-lyase,cystathionine gamma-lyase,Null mut\nant is viable, cysteine auxotroph\n Cond91:kim4\n mYBR261C:Unknown ,, Unknown\n Cond28:cla4(haploid)\n mRNH35:RNase H(35), a 35 kDa ribonuclease H,,Null mutant is viable \nbut shows 75% reduction of RNase H activity in cell extracts\n Cond81:hog1(haploid)\n Cond283:KAR2(tetpromoter)\n Cond103:msu1\n mTEF4:Translation elongation factor EF-1gamma,translation elongati\non factor EF-1gamma,\n Cond200:yel001c\n mOYE2:NAPDH dehydrogenase (old yellow enzyme), isoform 2,NAPDH deh\nydrogenase (old yellow enzyme), isoform 2,Null mutant is via\nble\n mGPD1:glycerol-3-phosphate dehydrogenase,glycerol-3-phosphate dehy\ndrogenase,lethal under conditions of osmotic stress, unable \nto grow on glycerol\n Cond285:RHO1(tetpromoter)\n Cond161:sod1(haploid)\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mZWF1:Glucose-6-phosphate dehydrogenase,glucose-6-phosphate dehydr\nogenase,sensitive to oxidizing agents; methionine requiring\n mPIN3:[PSI+] induction,,Other phenotypes: overexpression of PIN3 a\nllows for the induction of the [PSI+] prion in strains cured\n of [PIN+].\n mSYN8:Unknown ,, Unknown\n mFUR1:Regulation of the pyrimidine salvage pathway,UPRTase,Null mu\ntant is viable, resistant to 5-FU\n Cond61:fks1(haploid)\n mDEP1:Regulator of phospholipid metabolism,,Null mutant is viable\n Cond216:yer044c(haploid)\n mPTA1:pre-tRNA processing,,Null mutant is inviable; temperature-se\nnsitive mutant shows defects in pre-tRNA processing\n mERV46:ER vesicle protein of 46 kDa,ER-Golgi transport vesicle prot\nein,Null mutant is viable but cold sensitive.\n mYOR041C:Unknown ,, Unknown\n mCDC19:Required for START A in the cell cycle and sporulation,pyruv\nate kinase,Null mutant is inviable. cdc19 mutants are pyruva\nte kinase deficient and show cell division cycle blocked at \n36 degrees C\n mCAF120:Hypothetical ORF,,Null mutant is viable\n Cond884:10\n
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Computational Genomics Lab, Tel-Aviv uniresity