Module number 1248




Database revision : gnsdb28.10
Date : Tue Feb 25 17:01:41 2003
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mHSP104:involved in thermal and ethanol tolerance, inheritance of [P\nSI+], and reactivation of mRNA splicing after heat shock,hea\nt shock protein 104,Null mutant is viable and defective in i\nnduced thermotolerance\n mBDH1:Unknown ,, Unknown\n mCAK1:binds and phosphorylates Cdc28p,cyclin-dependent kinase-acti\nvating kinase,Null mutant is inviable; temperature-sensitive\n mutant confers a G2 delay accompanied by low Cdc28p protein\n kinase activity\n mSDH2:Succinate dehydrogenase (ubiquinone) iron-sulfur protein sub\nunit,succinate dehydrogenase (ubiquinone) iron-sulfur protei\nn subunit,Null mutant is viable\n mSIP2:Member of a family of proteins, including Sip1p and Gal83p, \nthat interact with Snf1p and Snf4p and are involved in the r\nesponse to glucose starvation,,Null mutant is viable\n mGDB1:Glycogen debranching enzyme; the enzyme that debranches the \nglycogen having a glucanotranferase + 1-6amyloglucosidase ac\ntivity,,Null mutant is viable but unable to degrade glycogen\n.\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n Cond410:diauxic_shift_timecourse_18.5_h\n Cond302:Heat_Shock_15_minutes_hs-1\n mACB1:Involved in transport of newly synthesized acyl-CoA esters f\nrom the fatty acid synthetase to acyl-CoA-consuming processe\ns,acyl-CoA-binding protein (ACBP)/diazepam binding inhibitor\n (DBI)/endozepine (EP),Null mutant is viable, slightly reduc\ned growth rate on ethanol\n Cond981:F82G_pho4D_10_mM_1NaPP1\n mYCR013C:Unknown ,, Unknown\n mHNT1:Hint homolog, member of the histidine triad superfamily of n\nucleotide-binding proteins,,\n mKAR2:Involved in translocation of nascent polypeptides across the\n ER membrane,HSP70 family , mammalian BiP (GPR78) homolog , \nHSP70 family , mammalian BiP (GPR78) homolog,null mutants ar\ne inviable; other mutants block karyogamy (nuclear fusion) d\nuring mating\n mYSC84:SH3 domain in C-terminus,,Null mutant is viable\n mCBP4:Essential for the expression and activity of ubiquinol-cytoc\nhrome c reductase,,Inability to respire, pleiotropic reducti\non in steady state levels of four subunits of ubiquinol-cyto\nchrome c reductase\n mYIL087C:Unknown ,, Unknown\n mYNL200C:Unknown ,, Unknown\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mSDP1:Unknown ,, Unknown\n Cond976:F82G_1_mM_1NaPP1\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond637:DES460_+_0.02%_MMS_-_60_min\n Cond373:1.5_mM_diamide_(40_min)\n mPST2:Protoplasts-SecreTed protein; the gene product was detected \namong the proteins secreted by regenerating protoplasts,,\n Cond822:tlc1_Expt.1_Passage_3\n mUBC5:ubiquitin-conjugating enzyme,ubiquitin-conjugating enzyme,vi\nable, ubc4/ubc5 double mutant is temperature sensitive\n mMAG1:3-methyladenine DNA glycosylase,3-methyladenine DNA glycosyl\nase,Null mutant is viable, deficient in 3-methyladenine DNA \nglycosylase activity and shows enhanced sensitivity to sever\nal monofunctional alkylating agents\n Cond802:CaFK30'\n mYOL150C:Unknown ,, Unknown\n mXBP1:DNA-binding transcriptional repressor,transcriptional repres\nsor,Null mutant is viable; overexpression of XBP1 leads to a\n slow-growth phenotype, lengthening of G1, an increase in ce\nll volume, and a repression of G1 cyclin expression\n mGPM2:Similar to GPM1 (phosphoglycerate mutase); converts 3-phosph\noglycerate to 2-phosphoglycerate in glycolysis,,Null mutant \nis viable, gpm2 gpm3 double deletion mutants exhibit no synt\nhetic phenotypes\n mYGR052W:Unknown ,, Unknown\n mTAL1:Transaldolase, enzyme in the pentose phosphate pathway,trans\naldolase, enzyme in the pentose phosphate pathway,Null mutan\nt is viable\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mAMS1:vacuolar alpha mannosidase,alpha mannosidase,null mutant is \nviable\n mPEP4:vacuolar proteinase A,vacuolar proteinase A,Null mutant is v\niable, proteinase deficient, phosphatase deficient; pep4 mut\nants exhibit a 60-70% reduction in total protein degradation\n during sporulation\n mYOR1:multispecific organic anion transporter important for tolera\nnce against toxic environmental organic anions,ABC transport\ner,Null mutant is viable but exhibits a slight growth defect\n; null mutant is hypersensitive to reveromycin A and fumonis\nin B1. Overexpression increases resistance to fumonisin B, s\nphingosine, and reveromycin A.\n mRPN13:Proteasome subunit,,Null mutant is viable but defective in d\negradation of ubiquitinated substrates.\n Cond312:Heat_Shock_015_minutes_hs-2\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond683:MHY1_(crt1)_vs._CRY1_(wild_type)_-_log_phase\n mHSP60:60 kDa heat shock protein,chaperonin , groEL homolog , chape\nronin , groEL homolog,Null mutant is inviable\n mRTN2:Unknown ,, Unknown\n mYJL161W:Unknown ,, Unknown\n mPYK2:Pyruvate kinase, glucose-repressed isoform,,Null mutant is v\niable and shows no obvious phenotypes; however, a pyk1 pyk2 \ndouble-deletion mutant shows growth defects more pronounced \nthan in the pyk1 mutant strain\n mCYC7:iso-2-cytochrome c,iso-2-cytochrome c,Null mutant is viable\n mYOR052C:Unknown ,, Unknown\n Cond797:Ca15'\n mCOX15:cytochrome oxidase assembly factor,cytochrome oxidase assemb\nly factor,fail to synthesize cytochrome oxidase\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n mYOR161C:Unknown ,, Unknown\n mYFR017C:Unknown ,, Unknown\n mMDG1:multicopy suppressor of bem1 mutation, may be involved in G-\nprotein mediated signal transduction; binds cruciform DNA,,N\null mutant is viable. Deletion of MDG1 causes sterility in c\nells in which the wild-type G beta has been replaced by part\nly defective G beta derivatives\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYCP4:Protein with similarity to S. pombe brefeldin A resistance p\nrotein obr1 and E. coli WrbA protein which stimulates bindin\ng of Trp repressor to DNA,,\n mTTR1:Glutaredoxin (thioltransferase) (glutathione reductase),glut\naredoxin , thioltransferase/glutathione reductase,\n mPOR1:Outer mitochondrial membrane porin (voltage-dependent anion \nchannel, or VDAC),porin , voltage-dependent anion channel (V\nDAC),Null mutant is viable, shows strain-dependent delayed g\nrowth on glycerol\n mYNL274C:Unknown ,, Unknown\n mYBR137W:Unknown ,, Unknown\n mGCV3:H-protein subunit of the glycine cleavage system,glycine cle\navage system H-protein subunit,Null mutant is viable but doe\ns not grow if glycine is the sole nitrogen source\n mNDI1:NADH dehydrogenase (ubiquinone),NADH dehydrogenase (ubiquino\nne),\n mGLK1:Glucose phosphorylation,glucokinase,Null mutant is viable wi\nth no discernible difference from wild-type; hxk1, hxk2, glk\n1 triple null mutants are unable to grow on any sugar except\n galactose and fail to sporulate\n mYLR152C:Unknown ,, Unknown\n mTRX2:thioredoxin,thioredoxin,Null mutant is viable; trx1-trx2 dou\nble mutant shows prolonged S phase, shortened G(sub)1 and me\nthionine auxotrophy\n mAPD1:actin patches distal,,\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYPL247C:Unknown ,, Unknown\n mSDS24:Similar to S. pombe SDS23, suppresses DIS2, localized to the\n nucleus,,Null mutant is viable\n mTPO1:Polyamine transport protein,,\n mYFR003C:Unknown ,, Unknown\n mGRX1:Glutaredoxin,glutaredoxin,Null mutant is viable but sensitiv\ne to oxidative stress. grx1 grx2 null mutants are viable but\n lack heat-stable oxidoreductase activity.\n Cond370:1.5_mM_diamide_(10_min)\n Cond374:1.5_mM_diamide_(50_min)\n mYAL061W:Unknown ,, Unknown\n mYDR154C:Unknown ,, Unknown\n mYER067W:Unknown ,, Unknown\n Cond975:WT_1_mM_1NaPP1\n mYGR243W:Unknown ,, Unknown\n mYOR285W:Unknown ,, Unknown\n mAUT7:Forms a protein complex with Aut2p to mediate attachment of \nautophagosomes to microtubules. Defective in maturation of t\nhe vacuolar protein, aminopeptidase I,similar to LC3, a micr\notubule-associated protein from rat,Null mutant is viable bu\nt lacks autophagocytosis and is unable to sporulate. AUT7 is\n a suppressor of mutant phenotypes of aut2-1 cells. Uptake o\nf precursor Aminopeptidase I into the vacuole depends on Aut\n2p and Aut7p.\n Cond303:Heat_Shock_20_minutes_hs-1\n Cond977:F82G_pho4D_1_mM_1NaPP1\n Cond636:DES460_+_0.2%_MMS_-_45_min\n Cond639:DES460_+_0.02%_MMS_-_120_min\n Cond973:WT_vs_F82G_1\n mYKL091C:Unknown ,, Unknown\n mAGP2:General amino acid permease with broad substrate specificity\n,amino acid permease,Null mutant is viable; loss of growth o\nn some amino acids as nitrogen source (leu, thr) in a strain\n which has no Gap1p or Agp1p function\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n mYAL004W:Unknown ,, Unknown\n mBMH1:Brain Modulosignalin Homolog,member of conserved eukaryotic \n14-3-3 gene family,Null mutant is viable; bmh1 bmh2 double m\nutant is inviable; (in strain Sigma-1278b, required for pseu\ndohyphal development but not for viability)\n mYSA1:Protein with weak homology to D. melanogaster serendipity pr\notein and X. laevis basis fibroblast growth factor,,\n Cond837:tlc1_Expt.2_Passage_9__\n Cond801:CaFK15'\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYPR098C:Unknown ,, Unknown\n mHSP82:82 kDa heat shock protein; homolog of mammalian Hsp90,heat s\nhock protein 90 , mammalian Hsp90 homolog , heat shock prote\nin 90 , mammalian Hsp90 homolog,Null mutant is viable at 25 \ndegrees C; ability to grow at higher temperatures varies wit\nh gene copy number\n Cond320:heat_shock_17_to_37,_20_minutes\n Cond836:tlc1_Expt.2_Passage_8\n Cond978:pho85D_1_mM_1NaPP1_\n Cond982:pho85D_10_mM_1NaPP1_\n Cond301:Heat_Shock_10_minutes_hs-1\n Calcin.CaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond369:1.5_mM_diamide_(5_min)\n mPGM2:Phosphoglucomutase,phosphoglucomutase,Null mutant is viable,\n pgm1 pgm2 deletion mutants fail to grow on galactose\n mUIP4:Unknown ,, Unknown\n mTPI1:triosephosphate isomerase,triosephosphate isomerase,Null mut\nant is viable.\n mYDR533C:Unknown ,, Unknown\n mMSC1:Meiotic Sister-Chromatid recombination,,\n mHSP10:Homolog of E. coli GroES protein; regulates Hsp60, the yeast\n mitochondrial chaperonin, and is thereby involved in protei\nn folding and sorting in mitochondria,heat shock protein 10,\nNull mutant is inviable; temperature-sensitive mutants are a\nvailable\n mHSP12:induced by heat shock, entry into stationary phase, depletio\nn of glucose, and addition of lipids (fatty acids),heat shoc\nk protein 12,Null mutant is viable, but shows induction of h\neat shock response under conditions normally associated with\n low-level HSP12 expression\n mYBR052C:Unknown ,, Unknown\n Cond800:CaFK5'\n mYBR241C:Unknown ,, Unknown\n mYMR31:mitochondrial ribosomal protein (precursor),mitochondrial ri\nbosomal protein,\n mYBL064C:Unknown ,, Unknown\n mDCS2:Unknown ,, Unknown\n mGTT1:Glutathione Transferase,glutathione transferase,Null mutant \nis viable, heat shock sensitive at stationary phase\n Cond375:1.5_mM_diamide_(60_min)\n Cond371:1.5_mM_diamide_(20_min)\n Cond323:heat_shock_29_to_37,_20_minutes\n mYJL055W:Unknown ,, Unknown\n mSHP1:isolated as a suppressor of the lethality caused by overexpr\nession of the phosphoprotein phosphatase 1 catalytic subuniu\nt encoded by GLC7,,Null mutant is viable; sporulation defect\nive, slow growth; is deficient in glycogen accumulation; low\n Glc7p specific activity\n mYDR134C:Unknown ,, Unknown\n Cond832:tlc1_Expt.2_Passage_4\n mSSN8:Component of RNA polymerase II holoenzyme, involved in RNA p\nol II carboxy-terminal domain phosphorylation. Activity of t\nhe kinase (SSN3)/cyclin (SSN8) pair required, along with SSN\n6 & TUP1, for transcriptional repression of a-specific genes\n,C-type cyclin , associates with the Ssn3p cyclin-dependent \nkinase , C-type cyclin , associates with the Ssn3p cyclin-de\npendent kinase , C-type cyclin , associates with the Ssn3p c\nyclin-dependent kinase , C-type cyclin , associates with the\n Ssn3p cyclin-dependent kinase,null is viable, exhibits set \nof phenotypes common to strains defective in SSN6/TUP1-media\nted transcriptional repression. Other mutations show unsched\nuled meiotic gene expression (derepression of early meiotic \ngenes), suppression of SNF1.\n mEMG1:Essential for Mitotic Growth,ribosome biogenesis,Lethal\n mCMK1:Calmodulin-dependent protein kinase,calmodulin-dependent pro\ntein kinase,Null mutant is viable\n Cond326:29C_to_33C_-_15_minutes\n Cond855:pm38-30\n mTSA1:antioxidant enzyme that provides protection against oxidatio\nn systems capable of generating reactive oxygen and sulfur s\npecies,thioredoxin-peroxidase (TPx); reduces H2O2 and alkyl \nhydroperoxides with the use of hydrogens provided by thiored\noxin, thioredoxin reductase, and NADPH,Null mutant is viable\n, grows slower than wild-type under aerobic conditions\n mDOG2:2-deoxyglucose-6-phosphate phosphatase,2-deoxyglucose-6-phos\nphate phosphatase,\n Cond638:DES460_+_0.02%_MMS_-_90_min\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n Cond820:tlc1_Expt.1_Passage_1\n mAYR1:Subcellular location of Ayr1p: lipid particles and endoplasm\nic reticulum of the yeast,1-acyl dihydroxyacetone phosphate \nreductase,Null mutant is viable\n Cond635:DES460_+_0.02%_MMS_-_30_min\n Stress.WeakHeat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mPRE10:proteasome component YC1 (protease yscE subunit 1),proteasom\ne component YC1 (protease yscE subunit 1),Null mutant is inv\niable\n Cond322:heat_shock_25_to_37,_20_minutes\n mGCY1:Galactose-induced transcript, product is homologous to mamma\nlian aldo/keto reductases, as well as to gamma-crystallin, a\n vertebrate eye lens protein,,Null mutant is viable\n mYDL124W:Unknown ,, Unknown\n mYDL110C:Unknown ,, Unknown\n mRPN6:Regulatory Particle Non-ATPase, homolog of mammalian proteas\nomal subunit S9/p44.5.,proteasome regulatory particle subuni\nt,Null mutant is inviable\n mARA1:D-arabinose dehydrogenase,D-arabinose dehydrogenase,Null mut\nant is viable but cannot produce D-arabinono-1,4-lactone, a \nprecursor of D-erythroascorbic acid\n Cond827:tlc1_Expt.1_Passage_8\n mHSP26:heat shock protein 26,heat shock protein 26,Null mutant is v\niable; hsp26 hsp42 double deletion mutants are viable\n mYDL023C:Unknown ,, Unknown\n mHXK1:Glucose phosphorylation,hexokinase I (PI) (also called hexok\ninase A),Null mutant is viable, is able to ferment fructose,\n and has little or no effect on glucose repression; hxk1, hx\nk2 double null mutant cannot ferment fructose and fails to s\nhow glucose repression at SUC2, CYC1, GAL10\n mHHT1:Histone H3 (HHT1 and HHT2 code for identical proteins),histo\nne H3 (HHT1 and HHT2 code for identical proteins),Null mutan\nt is viable\n mOPI3:Second and third steps of methylation pathway for phosphatid\nylcholine biosynthesis,methylene-fatty-acyl-phospholipid syn\nthase (unsaturated phospholipid N-methyltransferase),Null mu\ntant is viable, temperature sensitive in the presence of mon\nomethylethanolamine, exhibits an inositol secretion phenotyp\ne\n mCDC19:Required for START A in the cell cycle and sporulation,pyruv\nate kinase,Null mutant is inviable. cdc19 mutants are pyruva\nte kinase deficient and show cell division cycle blocked at \n36 degrees C\n mPRE4:B-type subunit of proteasome, euk. & archae. multicatalytic \nproteinase complex likelyinvolved in an ATP/ubiquitin-depend\nent nonlysosomal proteolytic pathway. eukary: the proteasome\n is composed of ~24 subunits forming a ring-shaped structure\n,necessary for peptidyl glutamyl peptide hydrolyzing activit\ny , proteasome subunit,Null mutant is inviable\n Cond434:DBY7286_37degree_heat_-_20_min\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mCPR6:a cyclophilin related to the mammalian CyP-40; physically in\nteracts with RPD3 gene product,cyclophilin 40 , peptidyl-pro\nlyl cis-trans isomerase (PPIase),Null mutant is viable, has \nnormal growth rate\n mPRE6:alpha-type of subunit of 20S proteasome,20S proteasome alpha\n-type subunit,Null mutant is inviable\n mPRE7:proteasome subunit,proteasome subunit,Null mutant is inviabl\ne\n mPRE8:proteasome component Y7,proteasome component Y7,\n mUGP1:Uridinephosphoglucose pyrophosphorylase,uridinephosphoglucos\ne pyrophosphorylase,Null mutant is inviable, probably due to\n inability to properly form the cell wall\n Cond321:heat_shock_21_to_37,_20_minutes\n mUGA1:gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate ami\nnotransferase),gamma-aminobutyrate (GABA) transaminase (4-am\ninobutyrate aminotransferase),\n mTDH1:Glyceraldehyde-3-phosphate dehydrogenase 1,glyceraldehyde-3-\nphosphate dehydrogenase 1,Null mutant is viable, tdh1 tdh2 a\nnd tdh1 tdh3 double mutants grow at wild type rates when eth\nanol is used as a carbon source\n mTDH2:glyceraldehyde 3-phosphate dehydrogenase,glyceraldehyde 3-ph\nosphate dehydrogenase,Null mutant is viable, grow poorly on \nglucose, grow as well as wild-type on ethanol media, tdh2 td\nh3 double deletion mutants are inviable\n mUFD1:Ubiquitin fusion degradation protein,,Homozygous ufd1-1 muta\nnt diploids exhibit sporulation defects.\n mOM45:45-kDa mitochondrial outer membrane protein,45 kDa mitochond\nrial outer membrane protein,Null mutant is viable and shows \nnormal growth, viability, mitochondrial function and mitocho\nndrial protein import\n mSPI1:Stationary Phase Induced; strongly expressed during stationa\nry phase, and trancription is dependent on MSN2/MSN4.,,\n Cond329:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_5_minutes\n Cond835:tlc1_Expt.2_Passage_7\n mSYM1:Unknown ,, Unknown\n mALD4:Glucose repressed. Utilizes NADP+ or NAD+ as a coenzyme equa\nlly well. (sold by SIGMA under the catalogue number A5550, a\nccording to A. Blomberg).,aldehyde dehydrogenase,\n mYCR061W:Unknown ,, Unknown\n mSOL4:similar to SOL3,,\n mYFL068W:Unknown ,, Unknown\n mALD6:Utilizes NADP+ as the preferred coenzyme. Activated by Mg2+.\n,aldehyde dehydrogenase,Null mutant is viable, grows at appr\noximately one-third the rate of wild-type, unable to grow on\n ethanol as a carbon source\n mGRE2:induced by osmotic stress; similar to dihydroflavonol 4-redu\nctase from plants,,\n mYPT1:involved in the secretion pathway at the ER-to-Golgi step; r\nequired for sporulation,GTP-binding protein , ras homolog , \nsimilar to mammalian Rab1A protein,Null mutant is inviable, \nat non-permissive temp, ts and cs mutants accumulate ER memb\nranes and small vesicles, fail to process invertase and othe\nr secreted proteins, and show cytoskeletal defects; ypt1 cau\nses lethality during nitrogen starvation\n mPDI1:protein disulfide isomerase,protein disulfide isomerase,Null\n mutant is inviable\n mCOX5B:Cytochrome-c oxidase chain Vb,cytochrome c oxidase chain Vb,\nNull mutant is viable\n mRIM4:Regulator of IMe2 expression,RNA-binding protein of the RRM \nclass (putative),Null mutant is viable. Homozygous null dipl\noid fails to sporulate, does not form meiosis I or II spindl\nes, and exhibits reduced expression of early and middle spor\nulation-specific genes. Null mutant is suppressed by hyperac\ntive Ime2p derivative, but not by overexpression IME1\n mYPL004C:Unknown ,, Unknown\n mBCY1:Involved in heat shock resistance, glycogen accumulation, an\nd sporulation,cAMP-dependent protein kinase regulatory subun\nit,Null mutant is viable; sra1 mutants are associated with r\neduction of glycogen accumulation, temperature sensitivity, \nreduced growth rate on maltose and sucrose, inability to gro\nw on galactose and nonfermentable carbon sources and nitroge\nn starvation intolerance. Cells lacking Sra1p are constituti\nve for cAPK activity resulting in meiotic arrest prior to pr\nemeiotic DNA synthesis\n Cond372:1.5_mM_diamide_(30_min)\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYNK1:Nucleoside diphosphate kinase,nucleoside diphosphate kinase,\nNull mutant is viable, exhibits no defects in growth rate, s\npore formation, mating ability, or morphology\n mKIN82:Putative serine/threonine protein kinase most similar to cyc\nlic nucleotide-dependent protein kinase subfamily and the pr\notein kinase C subfamily,serine/threonine kinase (putative) \n, similar to cyclic nucleotide-dependent protein kinase subf\namily and the protein kinase C subfamily,Null mutant is viab\nle\n Cond974:WT_vs_F82G_2\n Cond324:heat_shock_33_to_37,_20_minutes\n mSSA1:Stress-seventy subfamily A,heat shock protein of HSP70 famil\ny,Null mutant is viable, temperature sensitive; ssa1 ssa2 ss\na4 strains are inviable; an intact copy of SSA3 regulated by\n the constitutive SSA2 promoter is capable of rescuing the i\nnviability of an ssa1 ssa2 ssa4 strain\n mGSY1:Highly similar to GSY2. GSY2 is the predominantly expressed \nglycogen synthase,glycogen synthase (UDP-glucose-starch gluc\nosyltransferase),Null mutant is viable. Mutant lacking both \nGSY1 and GSY2 is viable but lacks glycogen synthase activity\n and glycogen deposition\n mTPS2:Trehalose-6-phosphate phosphatase,trehalose-6-phosphate phos\nphatase,Null mutant is viable, exhibits complete loss of tre\nhalose-6-phosphate phosphatase activity, measured in vitro, \nand accumulation of excessive amounts of trehalose-6-phospha\nte instead of trehalose upon heat shock or entrance into sta\ntionary phase in vivo; null mutant is temperature sensitive,\n tps2 (pfk3) pfk1 double mutants are glucose negative\n mSSA2:member of 70 kDa heat shock protein family,HSP70 family,Null\n mutant is viable, temperature sensitive; ssa1 ssa2 ssa4 str\nains are inviable; an intact copy of SSA3 regulated by the c\nonstitutive SSA2 promoter is capable of rescuing the inviabi\nlity of an ssa1 ssa2 ssa4 strain\n mACP1:mitochondrial acyl carrier protein,acyl carrier protein,The \nnull mutant is viable but respiratory-deficient and contains\n only 5-10% of the wild-type amount of lipoic acid.\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYLL023C:Unknown ,, Unknown\n mPNC1:pyrazinamidase and nicotinamidase,nicotinamidase , pyrazinam\nidase,Null mutant is viable\n Cond831:tlc1_Expt.2_Passage_3\n mEMI5:Unknown ,, Unknown\n mYIR016W:Unknown ,, Unknown\n mWTM1:WD repeat containing transcriptional modulator 1,transcripti\nonal modulator,Null mutant is viable\n mYPL185W:Unknown ,, Unknown\n mSTF2:ATPase stabilizing factor,ATPase stabilizing factor,\n mYDR230W:Unknown ,, Unknown\n mYDC1:Yeast dihydro-ceramidase,alkaline dihydroceramidase with min\nor reverse activity,Null mutant is viable.\n Cond442:DBYyap1-_+_0.3_mM_H2O2_(20_min)\n mYLR345W:Unknown ,, Unknown\n Cond980:F82G_10_mM_1NaPP1\n Cond979:WT_10_mM_1NaPP1\n Cond304:Heat_Shock_30_minutes_hs-1\n mHTB2:Histone H2B (HTB1 and HTB2 code for nearly identical protein\ns),histone H2B (HTB1 and HTB2 code for nearly identical prot\neins),Null mutant is viable. Deletion of the HTA2-HTB2 (TRT2\n) locus has no reported observable phenotypes, presumably be\ncause HTA1-HTB1 (TRT1) expression is upregulated and can com\npensate in the absence of TRT2\n mSSA1 mHSP82 mCPR6 mHTB2 mMAG1 mHHT1 mYBR052C mPST2 mYCP4 mBMH1 mYFR017C mEMG1 mYPL004C mHSP60 mHSP10
this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity