Module number 1227




Database revision : gnsdb28.10
Date : Tue Feb 25 17:41:23 2003
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mCPT1:Phospholipid biosynthesis,sn-1,2-diacylglycerol cholinephosp\nhotransferase,Null mutant is viable, cpt1 ept1 double deleti\non mutants are viable\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast.  Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n mTFB2:Transcription/repair factor TFIIH subunit,TFIIH subunit,Null\n mutant is inviable; a c-terminal deletion mutant is associa\nted with defects in nucleotide excision repair (as demonstra\nted by UV sensitivity\n mYMR067C:Unknown ,, Unknown\n mMCM16:Involved in a nonessential role that governs the kinetochore\n-microtubule mediated process of chromosome segregation,,Nul\nl mutant is viable, exhibits increased sensitivity to the an\nitmitotic drugs benomyl and thiabenzadole; exhibits a high r\nate of chromosome III loss without a significant increase in\n recombination frequency, may exhibit altered kinetochore as\nsembly\n mYJR001W:Unknown ,, Unknown\n mYPL141C:Unknown ,, Unknown\n mMKK1:Mitogen-activated kinase-kinase involved in protein kinase C\n pathway,MAP kinase kinase (MEK),Null mutant is viable but c\nannot grow on glycerol, is sensitive to nitrogen starvation,\n and cannot grow at elevated temperatures unless supplemente\nd with sorbitol.\n mPSY2:Unknown ,, Unknown\n mYJL149W:Unknown ,, Unknown\n mPDR17:involved in pleiotropic drug resistance by controlling lipid\ns in various cellular compartments,Pdr16p homolog , Sec14p h\nomolog,Null mutant is viable, exhibits no observable phenoty\npes; pdr16 pdr17 double deletion mutants exhibit altered lip\nid levels and drug hypersensitivity\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n mYOR129C:Unknown ,, Unknown\n mYML108W:Unknown ,, Unknown\n mYDR239C:Unknown ,, Unknown\n mYKL086W:Unknown ,, Unknown\n mRNQ1:Rich in asparagine (N) and glutamine (Q),transferable epigen\netic modifier,\n mYNL116W:Unknown ,, Unknown\n mDAL80:Negative regulator of multiple nitrogen catabolic genes,GATA\n family transcriptional repressor,Null mutant is viable, def\nicient in allantoin degradation\n mYML018C:Unknown ,, Unknown\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mAHP1:alkyl hydroperoxide reductase,alkyl hydroperoxide reductase,\nhypersensitive to tert-butyl hydroperoxide\n mYNR048W:Unknown ,, Unknown\n mECM7:Involved in cell wall maintenance,,A Tn3 insertion into this\n gene causes hypersensitivity to the cell surface polymer pe\nrturbing agent calcofluor white.\n mYOR072W:Unknown ,, Unknown\n mYNL108C:Unknown ,, Unknown\n mAHC1:Ada Histone acetyltransferase complex component ,Ada histone\n acetyltransferase complex component,Null mutant is viable\n mYHR176W:Unknown ,, Unknown\n mMEP1:ammonia permease,ammonia permease,\n mECM37:ExtraCellular Mutant,,A Tn3 insertion into this gene causes \nhypersensitivity to the cell surface polymer perturbing agen\nt calcofluor white.\n mYMR166C:Unknown ,, Unknown\n mNNT1:Unknown ,, Unknown\n Cond947:W303_YPA\n mKRE1:cell wall beta-glucan assembly,,Null mutant is viable, exhib\nits reduction in cell wall (1--6)-beta-glucan\n mYPL035C:Unknown ,, Unknown\n mYOL047C:Unknown ,, Unknown\n Cond948:W303_ume6_YPA_\n Cond937:t=0\n mCAC2:Involved in DNA-replication-linked nucleosome assembly; homo\nlogous to the p60 subunit of the Human CAF-I,chromatin assem\nbly factor-I (CAF-I) p60 subunit,Null mutant is viable, but \nis sensitive to UV irradiation\n mGSP2:maintenance of nuclear organization; homologous to mammalian\n Ran, a small nuclear GTPase of the ras superfamily,GTP-bind\ning protein , Gsp1p homolog,Null mutant is viable\n mYOL085C:Unknown ,, Unknown\n mYHR199C:Unknown ,, Unknown\n mYOR044W:Unknown ,, Unknown\n mYLR415C:Unknown ,, Unknown\n mDBF20:kinase required for late nuclear division,kinase required fo\nr late nuclear division,Dumbell formation\n mVPS17:Peripheral membrane protein required for vacuolar protein so\nrting,,Null mutant is viable, exhibits defect in vacuolar mo\nrphology and protein sorting\n mICY2:Interacting with the cytoskeleton,,\n mCAF120:Hypothetical ORF,,Null mutant is viable\n

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Computational Genomics Lab, Tel-Aviv uniresity