Module number 1204




Database revision : gnsdb28.10
Date : Tue Feb 25 17:37:49 2003
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Cond796:Ca5'\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n mBNI5:bud neck involved; localizes to mother-bud neck,,Null mutant\n is viable, interacts genetically with CDC12 (septin) gene\n Cond798:Ca30'\n mYOR145C:Unknown ,, Unknown\n mPOP1:Required for processing of pre-tRNAs and the 5.8S rRNA precu\nrsor,nuclear RNase P and RNase MRP component,Null mutant is \ninviable; temperature-sensitive mutant shows defect in proce\nssing pre-tRNAs and pre-rRNA at nonpermissive temperature\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n Cond302:Heat_Shock_15_minutes_hs-1\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond981:F82G_pho4D_10_mM_1NaPP1\n mNSA1:Nop seven associated,ribosome biogenesis,\n Cond761:Heat_30'\n mAAH1:adenine aminohydrolase (adenine deaminase),adenine aminohydr\nolase (adenine deaminase),Null mutant is viable\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond315:37C_to_25C_shock_-_15_min\n Cond976:F82G_1_mM_1NaPP1\n Cond416:YPD_10_h__ypd-2\n Cond425:YPD_stationary_phase_12_h_ypd-1\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond810:Na45'\n Cond911:(83i5)_S150-2B_YPD_NormInt\n Cond637:DES460_+_0.02%_MMS_-_60_min\n Cond373:1.5_mM_diamide_(40_min)\n Cond409:diauxic_shift_timecourse_15.5_h\n Cond300:Heat_Shock_05_minutes_hs-1\n Cond814:Na+FK45'\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond769:Acid_80'\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond245:ymr014w\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond335:constant_0.32_mM_H2O2_(10_min)_redo\n Cond395:Nitrogen_Depletion_30_min.\n mRPC31:31-kDa subunit of RNA polymerase III (C); HMG1 like protein,\nHMG1-like protein , RNA polymerase III (C) 31 kDa subunit , \nHMG1-like protein , RNA polymerase III (C) 31 kDa subunit,Nu\nll mutant is inviable\n mPRP2:Dead-box protein required for the first catalytic event of p\nre-mRNA splicing.,RNA splicing factor RNA-dependent NTPase w\nith DEAD-box motif,The null mutant is inviable. Temperature-\nsensitive alleles arrest with an accumulation of unprocessed\n pre-mRNA from intron-containing genes. An in vivo and in vi\ntro temperature-sensitive allele of prp2 is often used to fa\ncilitate the isolation of pre-catalytic spliceosomes.\n Cond553:alpha14\n Cond312:Heat_Shock_015_minutes_hs-2\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond569:cdc15_10\n mRIA1:RIbosome Assembly,,Null: quasi essential. Other phenotypes: \nDepletion of Ria1p leads to modification of the polysome pro\nfile, with the apperance of halfmers and a reduced level of \n60S subunits.\n Cond797:Ca15'\n Cond367:dtt_240_min_dtt-2\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond481:WT+/-100mM3AT(SetB)(491)\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond385:Hypo-osmotic_shock_-_15_min\n Cond378:1M_sorbitol_-_15_min\n mNOG2:Nuclear/Nucleolar GTP-binding protein 2,part of a pre-60S co\nmplex,Null: lethal. Other phenotypes: A gal1::nog2 mutant sh\nows 60S maturation defect in glucose repressive conditions.\n Cond427:YPD_stationary_phase_2_d_ypd-1\n Cond662:mec1_plus_gamma_5_min\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond945:W303_YPD\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond443:DBYyap1_+_0.32_mM_H2O2_(20_min)\n Cond833:tlc1_Expt.2_Passage_5\n Cond687:gal1+gal\n Cond374:1.5_mM_diamide_(50_min)\n Cond781:Peroxide_20'\n Cond706:gal2gal80-gal\n Cond370:1.5_mM_diamide_(10_min)\n Cond634:DES460_+_0.02%_MMS_-_15_min\n Cond325:29C_to_33C_-_5_minutes\n Cond809:Na30'\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond965:ndt80_delete_mid_g/r_ratio_\n Cond787:NaCl_45'\n Cond859:ms221-30\n Cond366:dtt_120_min_dtt-2\n Cond828:tlc1_Expt.1_Passage_9\n Cond977:F82G_pho4D_1_mM_1NaPP1\n Cond303:Heat_Shock_20_minutes_hs-1\n Cond485:Low-Pi_vs_High-Pi_in_WT_(DBY7286)\n mKRI1:KRRI-Interacting protein 1,Krr1p binding protein,\n Cond570:cdc15_30\n Cond636:DES460_+_0.2%_MMS_-_45_min\n mYPL146C:Unknown ,, Unknown\n Cond441:DBYmsn2/4_(real_strain)_+_0.32_mM_H2O2_(20_min)\n Cond650:wt_plus_gamma_5_min\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond408:diauxic_shift_timecourse_13.5_h\n mRPC53:RNA polymerase III (C) subunit, homologus to human BN51 prot\nein,RNA polymerase III subunit,Null mutant is inviable; temp\nerature sensitive mutants show rapid inhibition of tRNA synt\nhesis after shift to restricitive temperature and arrest in \nG1\n Cond837:tlc1_Expt.2_Passage_9__\n Cond856:pm38-qtop\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond801:CaFK15'\n Cond664:mec1_plus_gamma_20_min\n Cond390:aa_starv_0.5_h\n Cond320:heat_shock_17_to_37,_20_minutes\n Cond836:tlc1_Expt.2_Passage_8\n Cond316:37C_to_25C_shock_-_30_min\n Cond396:Nitrogen_Depletion_1_h\n Cond462:25_deg_growth_ct-1\n Cond658:DES460_(wt)_-_mock_irradiation_-_5_min\n mDIP2:DOM34 Interacting Protein,,\n Cond301:Heat_Shock_10_minutes_hs-1\n Cond982:pho85D_10_mM_1NaPP1_\n Calcin.CaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond887:t-BuOOH\n Cond369:1.5_mM_diamide_(5_min)\n Cond552:alpha7\n Cond763:Heat_60'\n Cond440:DBYmsn2msn4_(good_strain)_+_0.32_mM_H2O2\n Cond941:SK1_YPD\n Cond337:constant_0.32_mM_H2O2_(30_min)_redo\n mDUS1:tRNA dihydrouridine synthase,tRNA dihydrouridine synthase,\n Cond782:Peroxide_40'\n Cond800:CaFK5'\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond414:YPD_6_h_ypd-2\n Cond386:Hypo-osmotic_shock_-_30_min\n Cond967:swi1,_YPD_(c)\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond371:1.5_mM_diamide_(20_min)\n mYNL313C:Unknown ,, Unknown\n mYNR054C:Unknown ,, Unknown\n Cond323:heat_shock_29_to_37,_20_minutes\n Cond488:pho85_vs_WT\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Y-Stre.Acid:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Stress.DTT1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond286:YEF3(tetpromoter)\n Cond651:wt_plus_gamma_10_min\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond832:tlc1_Expt.2_Passage_4\n mNOB1:Unknown ,, Unknown\n Cond326:29C_to_33C_-_15_minutes\n Cond855:pm38-30\n Cond947:W303_YPA\n mYIL091C:Unknown ,, Unknown\n Cond426:YPD_stationary_phase_1_d_ypd-1\n Stress.WeakHeat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond635:DES460_+_0.02%_MMS_-_30_min\n Cond764:Heat_120'\n Cond322:heat_shock_25_to_37,_20_minutes\n Cond857:pm38-gtoe\n Cond357:2.5mM_DTT_045_min_dtt-1\n Cond229:yhr011w(**14)\n Cond758:Heat_0'_(A)\n Cond271:yor051c(**14)\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond317:37C_to_25C_shock_-_45_min\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mATC1:interacts with AIP3, localized to the nucleus,,\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast. Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mSIN4:involved in positive and negative regualtion of transcriptio\nn, possibly via changes in chromatin structure,RNA polymeras\ne II holoenzyme/mediator subunit,Null mutant is viable, temp\nerature sensitive, displays defects in both positive and neg\native regulation of transcription, suppresses Ty insertion m\nutations (Spt-), exhibits decreased superhelical density of \ncircular DNA molecules, exhibits expression from promoters l\nacking UAS elements; associated with a defect in RME1-depend\nent repression and a methionine or cysteine requirement, exh\nibits flocculant/lacy colony morphology, suppressor of snf/s\nwi mutations\n Cond424:YPD_stationary_phase_8_h_ypd-1\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond321:heat_shock_21_to_37,_20_minutes\n Cond783:Peroxide_60'\n Cond762:Heat_45'\n SwiSnf.swisnf:Whole-genome expression analysis of snf/swi mutants of Sacch\naromyces cerevisiae. Proc Natl Acad Sci U S A. 2000 Mar 28;\n97(7):3364-9.\n mNOC3:NucleOlar Complex 2; involved in the nuclear export of pre-r\nibosomes,,\n Cond329:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_5_minutes\n Y-Stre.NaCl:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond835:tlc1_Expt.2_Passage_7\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond882:zero3\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n Cond359:2.5mM_DTT_090_min_dtt-1\n mUTP5:Unknown ,, Unknown\n Cond117:pfd2(**14)\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond415:YPD_8_h_ypd-2\n Cond811:Na60'\n mUTP18:Unknown ,, Unknown\n mTRM2:tRNA methyltransferase,tRNA methyltransferase,\n Cond372:1.5_mM_diamide_(30_min)\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond336:constant_0.32_mM_H2O2_(20_min)_redo\n Cond360:2.5mM_DTT_120_min_dtt-1\n Cond324:heat_shock_33_to_37,_20_minutes\n Cond707:gal4gal80-gal\n pho.Pho:New components of a system for phosphate accumulation and po\nlyphosphate metabolism in Saccharomyces cerevisiae revealed \nby genomic expression analysis. Mol Biol Cell. 2000 Dec;11(\n12):4309-21.\n Cond334:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_30_minutes\n Cond411:diauxic_shift_timecourse_20.5_h\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond831:tlc1_Expt.2_Passage_3\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond815:Na+FK60'\n mYMR310C:Unknown ,, Unknown\n Cond442:DBYyap1-_+_0.3_mM_H2O2_(20_min)\n mTRF5:TRF4 homolog; TRF4/5 function is required for proper mitosis\n,DNA polymerase sigma,Null mutant is viable; trf4 trf5 mutan\nts are inviable; trf4 (ts) trf5 double mutant is hypersensit\nive to the anti-microtubule agent thiabendazole at a semi-pe\nrmissive temperature, overexpression of TRF5 complements the\n inviability of top1 trf4 mutants\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Y-Stre.Peroxide:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond980:F82G_10_mM_1NaPP1\n mRPC19:subunit common to RNA polymerases I (A) and III (C),RNA poly\nmerases I (A) and III (C) subunit,Null mutant is inviable\n Cond858:pm71-30\n mBUD21:protein possibly involved in protein synthesis,,Null mutant \nis viable; random budding in diploid null mutants; null has \nboth reduced growth and reduced protein synthesis rates\n Cond671:DES459_(mec1)_-_mock_irradiation_-_30_min\n Cond979:WT_10_mM_1NaPP1\n Cond304:Heat_Shock_30_minutes_hs-1\n Cond665:mec1_plus_gamma_30_min\n Cond703:gal10-gal\n Cond958:t0.5_g/r_ratio\n mUTP18 mDIP2 mYOR145C
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Computational Genomics Lab, Tel-Aviv uniresity