Module number 1184




Database revision : gnsdb28.10
Date : Tue Feb 25 17:02:34 2003
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Cond826:tlc1_Expt.1_Passage_7\n Cond663:mec1_plus_gamma_10_min\n Cond541:fus3D+50nMaF,30min/wtlog10(intensity)\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond565:alpha98\n Cond798:Ca30'\n Cond578:cdc15_130\n Cond649:dun1-_+_0.02%_MMS_-_120_min\n mASH1:Zinc-finger inhibitor of HO transcription which is asymmetri\ncally localized to the daughter cell nucleus,,Mutant ash1 da\nughters can transcribe HO and switch mating type\n Cond751: mEGT2:cell-cycle regulation protein, may be involved in the correc\nt timing of cell separation after cytokinesis,,\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond362:dtt_000_min__dtt-2\n Cond648:dun1-_+_0.02%_MMS_-_90_min\n mBUD9:among a group of genes whose products are necessary for bud-\nsite selection; likely involvement in positioning the proxim\nal pole signal,,In null mutants bipolar-budding cells bud pr\neferentially at distal pole\n Cond657:wt_plus_gamma_120_min\n Cond834:tlc1_Expt.2_Passage_6\n Cond579:cdc15_140\n Cond556:alpha35\n mYPL158C:Unknown ,, Unknown\n Cond573:cdc15_80\n mYLR049C:Unknown ,, Unknown\n Cond637:DES460_+_0.02%_MMS_-_60_min\n Cond822:tlc1_Expt.1_Passage_3\n Cond505:wtħ50nMaF,120minlog10(intensity)\n Cond802:CaFK30'\n mYLR194C:Unknown ,, Unknown\n Cond562:alpha77\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n Cond966:swi1,_YPD_(a)\n Cond530:GAL-BNI1D,3hrs.gallog10(intensity)\n Cond279:ERG11(tetpromoter)\n Cond553:alpha14\n Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n Cond580:cdc15_150\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n mSIC1:P40 inhibitor of Cdc28p-Clb5 protein kinase complex,,Null mu\ntant is viable, shows increased frequency of broken and lost\n chromosomes; sic1 deletion mutant rescues lethality of cln1\n cln2 cln3 triple mutant.\n Cond581:cdc15_160\n Cond54:erg3(haploid)\n Cond572:cdc15_70\n Cond558:alpha49\n Cond784:Peroxide_120'\n mYOR263C:Unknown ,, Unknown\n Cond662:mec1_plus_gamma_5_min\n Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n mRME1:mediates cell type control of sporulation; negatively regula\ntes IME1 and sporulation,negative regulator of meiosis; dire\nctly repressed by a1-a2 regulator , zinc finger protein,Null\n mutant is viable, rme1 allows alpha/alpha and a/a diploids \nto sporulate, and a and alpha haploids to form viable spores\n in the presence of spo13\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond653:wt_plus_gamma_30_min\n Cond833:tlc1_Expt.2_Passage_5\n Cond645:DES459_(mec1-)_+_0.02%_MMS_-_90_min\n Cond969:swi1,_minimal_(a)\n mPRY3:Pathogen Related in Sc, contains homology to the plant PR-1 \nclass of pathogen related proteins. The protein sequence is \nover 60% identical with the Pry2p & Pry3p over 145 resid. PR\nY1 is >35% identical (50% similar) to tobacco PR-1c protein.\n,,\n mSUN4:Protein involved in the aging process,,\n Cond737: mCTS1:Endochitinase,endochitinase,Null mutant is viable; exhibits \na defect in cell separation\n Cond555:alpha28\n Cond570:cdc15_30\n Cond636:DES460_+_0.2%_MMS_-_45_min\n Cond970:swi1,_minimal_(c)\n Cond639:DES460_+_0.02%_MMS_-_120_min\n Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond564:alpha91\n mYOR315W:Unknown ,, Unknown\n Cond652:wt_plus_gamma_20_min\n Cond664:mec1_plus_gamma_20_min\n Calcin.CaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond130:rml2(**13)\n Cond654:wt_plus_gamma_45_min\n Cond824:tlc1_Expt.1_Passage_5\n Cond224:CMD1(tetpromoter)\n Cond971:swi1,_minimal_(d)_\n Cond504:wtħ50nMaF,90minlog10(intensity)\n Cond561:alpha70\n mNIS1:Hypothetical ORF,,\n Cond99:med2(haploid)\n Cond124:rad6(haploid)\n Cond967:swi1,_YPD_(c)\n Cond656:wt_plus_gamma_90_min\n Cond53:erg2\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond940:6h\n Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n Cond832:tlc1_Expt.2_Passage_4\n mOLE1:delta-9-fatty acid desaturase,delta-9-fatty acid desaturase,\nThe null mutant is inviable but can be rescued by addition o\nf unsaturarted fatty acids to the growth medium. Some allele\ns are temperature-sensitive for growth and show defective in\ntracellular mitochondrial movement atthe non- permissive tem\nperature.\n mCLN2:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest; dominant mutation advances the G(sub)1- to\n S- phase transition and impairs ability of cells to arrest \nin G(sub)1 phase in response to external signals\n Cond638:DES460_+_0.02%_MMS_-_90_min\n Cond566:alpha105\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond341:constant_0.32_mM_H2O2_(80_min)_redo\n Cond340:constant_0.32_mM_H2O2_(60_min)_redo\n Cond646:DES459_(mec1-)_+_0.02%_MMS_-_120_min\n Cond557:alpha42\n Cond176:swi5\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mCST13:Chromosome STability,,Null mutant is viable, but grows slowl\ny and shows increased sensitivity to copper ions\n SwiSnf.swisnf:Whole-genome expression analysis of snf/swi mutants of Sacch\naromyces cerevisiae. Proc Natl Acad Sci U S A. 2000 Mar 28;\n97(7):3364-9.\n Cond278:CDC42(tetpromoter)\n Cond43:dot4\n Cond835:tlc1_Expt.2_Passage_7\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond563:alpha84\n Cond877:MMS\n Cond132:rnr1(haploid**9)\n Cond342:constant_0.32_mM_H2O2_(100_min)_redo\n Cond175:swi4\n Cond823:tlc1_Expt.1_Passage_4\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mHTA1:Histone H2A (HTA1 and HTA2 code for nearly identical protein\ns),histone H2A (HTA1 and HTA2 code for nearly identical prot\neins),Null mutant is viable\n mHTA2:Histone H2A (HTA1 and HTA2 code for nearly identical protein\ns),histone H2A (HTA1 and HTA2 code for nearly identical prot\neins),Null mutant is viable. Deletion of the HTA2-HTB2 (TRT2\n) locus has no reported observable phenotypes, presumably be\ncause HTA1-HTB1 (TRT1) expression is upregulated and can com\npensate in the absence of TRT2. Overexpression of TRT2 can s\nuppress Ty insertion mutations\n Cond153:sgs1\n Cond554:alpha21\n Cond738:90\n mHHF1:Histone H4 (HHF1 and HHF2 code for identical proteins),histo\nne H4 (HHF1 and HHF2 code for identical proteins),\n Cond575:cdc15_100\n Cond574:cdc15_90\n mPCL9:PHO85 cyclin,,Null mutant is viable.\n Cond380:1M_sorbitol_-_45_min_\n Cond831:tlc1_Expt.2_Passage_3\n Cond576:cdc15_110\n Cond560:alpha63\n mDSE1:Hypothetical ORF,,\n mDSE2:Hypothetical ORF,,\n Cond968:swi1,_YPD_(d)\n mDSE3:Hypothetical ORF,,\n Cond299:Tunicamycin\n mDSE4:Hypothetical ORF,,\n Cond736: Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond938:2h\n Cond559:alpha56\n Y-Stre.Peroxide:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond655:wt_plus_gamma_60_min\n mFAA3:acyl-CoA synthetase (long-chain fatty acid CoA ligase) (fatt\ny acid activator 3), activates endogenous but not imported f\natty acids and provides substrates for N-myristoylation,acyl\n-CoA synthase,Not essential for vegetative growth when fatty\n acid synthase (fas) is active\n Cond514:GAL-STE12,3hrs.gallog10(intensity)\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n mPIR1:Protein containing tandem internal repeats,contains tandem i\nnternal repeats,Null mutant is viable; pir1 hsp150 (pir2) do\nuble mutant and pir1 hsp150 (pir2) pir3 triple mutant are sl\now-growing on agar slab and sensitive to heat shock\n mHTB1:Histone H2B (HTB1 and HTB2 code for nearly identical protein\ns),histone H2B (HTB1 and HTB2 code for nearly identical prot\neins),Null mutant is viable\n mSCW11:Soluble Cell Wall protein,soluble cell wall protein,Null mut\nant is viable but exhibits defects in separation after divis\nion and displays flocculant growth.\n Cond665:mec1_plus_gamma_30_min\n Cond551:alpha0\n mHTB2:Histone H2B (HTB1 and HTB2 code for nearly identical protein\ns),histone H2B (HTB1 and HTB2 code for nearly identical prot\neins),Null mutant is viable. Deletion of the HTA2-HTB2 (TRT2\n) locus has no reported observable phenotypes, presumably be\ncause HTA1-HTB1 (TRT1) expression is upregulated and can com\npensate in the absence of TRT2\n mHHF1 mHTA1 mHTB1
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Computational Genomics Lab, Tel-Aviv uniresity