Module number 1127




Database revision : gnsdb28.10
Date : Tue Feb 25 17:36:52 2003
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Cond796:Ca5'\n Cond912:(99i1)_S150-2B_YPGL_NormInt\n Cond399:Nitrogen_Depletion_8_h\n Cond798:Ca30'\n Cond791:Sorbitol_30'\n Cond432:YPD_stationary_phase_22_d_ypd-1\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n mPUF6:member of the PUF protein family,,\n Cond675:MHY1_(dun1)_+_heat_20_min\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond981:F82G_pho4D_10_mM_1NaPP1\n Cond362:dtt_000_min__dtt-2\n mFYV7:Function required for Yeast Viability on toxin exposure,,K1 \nkiller toxin hypersensitivity\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond416:YPD_10_h__ypd-2\n Cond810:Na45'\n Cond289:Cycloheximide\n Cond637:DES460_+_0.02%_MMS_-_60_min\n Cond505:wtħ50nMaF,120minlog10(intensity)\n Cond439:DBY7286_+_0.3_mM_H2O2_(20_min)\n mNOP15:Nucleolar protein 15,ribosome biogenesis,\n mNOP16:Nucleolar protein 16,ribosome biogenesis,\n Cond435:DBYmsn2-4-_37degree_heat_-_20_min\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond429:YPD_stationary_phase_5_d_ypd-1\n Cond318:37C_to_25C_shock_-_60_min\n Cond673:DES460_(wild_type)_+_heat_20_min\n Cond155:she4\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond312:Heat_Shock_015_minutes_hs-2\n mENP2:Unknown ,, Unknown\n Cond569:cdc15_10\n Cond482:WT+/-100mM3AT(SetC)(KNY164)\n mLOC1:Localization of mRNA,,Mutant exhibits slow growth at 30C\n Cond430:YPD_stationary_phase_7_d_ypd-1\n mCGR1:coiled-coil growth-regulated,coiled-coil protein,Null mutant\n is inviable; CGR1 expression is down-regulated in the postd\niauxic growth phase\n Cond720:t0+SSD1,H44\n Cond427:YPD_stationary_phase_2_d_ypd-1\n Cond662:mec1_plus_gamma_5_min\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond945:W303_YPD\n Cond661:DES460_(wt)_-_mock_irradiation_-_90_min\n Cond443:DBYyap1_+_0.32_mM_H2O2_(20_min)\n Cond205:yel033w\n Cond833:tlc1_Expt.2_Passage_5\n Cond370:1.5_mM_diamide_(10_min)\n Cond706:gal2gal80-gal\n mYGR272C:Unknown ,, Unknown\n Cond571:cdc15_50\n Cond634:DES460_+_0.02%_MMS_-_15_min\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Calcin.crz1:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond461:21_deg_growth_ct-1\n Cond303:Heat_Shock_20_minutes_hs-1\n Cond485:Low-Pi_vs_High-Pi_in_WT_(DBY7286)\n Cond813:Na+FK30'\n Cond570:cdc15_30\n Cond636:DES460_+_0.2%_MMS_-_45_min\n mMRT4:mRna turnover 4,,Null mutant exhibits slow growth. ts mutat\nion results in decreased decay rates of mRNAs\n Cond639:DES460_+_0.02%_MMS_-_120_min\n Cond441:DBYmsn2/4_(real_strain)_+_0.32_mM_H2O2_(20_min)\n Cond408:diauxic_shift_timecourse_13.5_h\n Cond11:arg5,6\n mYJR071W:Unknown ,, Unknown\n Cond477:GCN4/gcn4Din100mM3AT(KNY164/KNY124)\n Cond801:CaFK15'\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond390:aa_starv_0.5_h\n Cond320:heat_shock_17_to_37,_20_minutes\n Cond316:37C_to_25C_shock_-_30_min\n Cond136:rpl27a(**4)\n Cond462:25_deg_growth_ct-1\n Cond982:pho85D_10_mM_1NaPP1_\n Cond301:Heat_Shock_10_minutes_hs-1\n Calcin.CaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond440:DBYmsn2msn4_(good_strain)_+_0.32_mM_H2O2\n Cond337:constant_0.32_mM_H2O2_(30_min)_redo\n Cond224:CMD1(tetpromoter)\n Cond770:Acid_100'\n Cond800:CaFK5'\n mYBL028C:Unknown ,, Unknown\n Cond745: mYOR287C:Unknown ,, Unknown\n Cond377:1M_sorbitol_-_5_min\n Cond371:1.5_mM_diamide_(20_min)\n Cond463:29_deg_growth_ct-1\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Stress.DTT1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond651:wt_plus_gamma_10_min\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mKRR1:Involved in cell division and spore germination,,Null mutant\n is inviable\n Cond832:tlc1_Expt.2_Passage_4\n Cond326:29C_to_33C_-_15_minutes\n Cond855:pm38-30\n mYLR198C:Unknown ,, Unknown\n Cond638:DES460_+_0.02%_MMS_-_90_min\n Cond635:DES460_+_0.02%_MMS_-_30_min\n Cond764:Heat_120'\n Cond857:pm38-gtoe\n Cond387:Hypo-osmotic_shock_-_45_min\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond317:37C_to_25C_shock_-_45_min\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast. Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond419:YPD_2_d_ypd-2\n Cond139:rpl8a\n Cond278:CDC42(tetpromoter)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond640:DES459_(mec1-)_+_0.02%_MMS_-_5_min\n mUTP9:Unknown ,, Unknown\n Cond806:crz1/Ca15'\n mUTP13:Unknown ,, Unknown\n mDBP9:Dead-Box Protein 9,,Null mutant is inviable\n Cond811:Na60'\n mYOR252W:Unknown ,, Unknown\n Cond372:1.5_mM_diamide_(30_min)\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond336:constant_0.32_mM_H2O2_(20_min)_redo\n Cond324:heat_shock_33_to_37,_20_minutes\n Cond707:gal4gal80-gal\n Cond334:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_30_minutes\n mSAS10:Something About Silencing 10,,Null mutant is inviable; derep\nresses HMR, HML and telomeres when overexpressed\n mIMP3:Interacts With Mpp10. Imp3p is a specific component of the U\n3 snoRNP and is required for pre-18S rRNA processing. It is \nnot required for U3 snoRNA stability.,,Null mutant is inviab\nle\n mIMP4:Interacts With Mpp10. Imp4p is a specific component of the U\n3 snoRNP and is required for pre-18S rRNA processing.,,Null \nmutant is inviable\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond815:Na+FK60'\n Cond968:swi1,_YPD_(d)\n Cond442:DBYyap1-_+_0.3_mM_H2O2_(20_min)\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Y-Stre.Peroxide:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond980:F82G_10_mM_1NaPP1\n Cond979:WT_10_mM_1NaPP1\n Cond428:YPD_stationary_phase_3_d_ypd-1\n Cond304:Heat_Shock_30_minutes_hs-1\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n Cond436:DBYmsn2/4_(real_strain)_+_37degrees_(20_min)\n Cond958:t0.5_g/r_ratio\n Cond330:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_15_minutes\n Cond277:AUR1(tetpromoter)\n mCIC1:Nop seven associated protein 3,ribosome biogenesis,\n Cond302:Heat_Shock_15_minutes_hs-1\n Cond418:YPD_1_d_ypd-2\n mRLP24:Ribosomal Like Protein 24,part of a pre-60S complex,Null: le\nthal. Other phenotypes: A gal1::rlp24 mutant shows a 60S mat\nuration defect under glucose repressive conditions..\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond761:Heat_30'\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond315:37C_to_25C_shock_-_15_min\n Cond976:F82G_1_mM_1NaPP1\n Cond467:steady_state_21_dec_C_ct-2\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond425:YPD_stationary_phase_12_h_ypd-1\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond373:1.5_mM_diamide_(40_min)\n Cond822:tlc1_Expt.1_Passage_3\n Cond409:diauxic_shift_timecourse_15.5_h\n Cond802:CaFK30'\n Cond300:Heat_Shock_05_minutes_hs-1\n mIPI2:Unknown ,, Unknown\n mIPI3:Unknown ,, Unknown\n mNMD3:putative Upf1p-interacting protein,factor required for a lat\ne assembly step of the 60S subunit,Null mutant is inviable, \nat nonpermissive temperature, nmd3 ts mutants exhibit decrea\nsed levels of 60S subunits resulting in formation of half-me\nr polysomes; nmd3 xrn1(kem1) double mutants are inviable\n Cond814:Na+FK45'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n Cond769:Acid_80'\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond245:ymr014w\n Cond335:constant_0.32_mM_H2O2_(10_min)_redo\n Cond395:Nitrogen_Depletion_30_min.\n mYKL082C:Unknown ,, Unknown\n Cond553:alpha14\n mNIP7:Nip7p is required for 60S ribosome subunit biogenesis,,Null \nmutant is inviable; in the temperature-sensitive mutant nip7\n-1, glycine 71 is replaced by aspartic acid\n mYDL062W:Unknown ,, Unknown\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond807:crz1/Ca30'\n Cond306:Heat_Shock_60_minutes_hs-1\n Cond797:Ca15'\n Cond361:2.5mM_DTT_180_min_dtt-1\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n Cond367:dtt_240_min_dtt-2\n mYDL063C:Unknown ,, Unknown\n Cond313:Heat_Shock_030inutes__hs-2\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond481:WT+/-100mM3AT(SetB)(491)\n Cond385:Hypo-osmotic_shock_-_15_min\n Cond818:crz1/Na30'\n Cond378:1M_sorbitol_-_15_min\n Cond358:2.5mM_DTT_060_min_dtt-1\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond365:dtt_060_min_dtt-2\n Cond374:1.5_mM_diamide_(50_min)\n Cond433:YPD_stationary_phase_28_d_ypd-1\n Cond809:Na30'\n Cond325:29C_to_33C_-_5_minutes\n Cond965:ndt80_delete_mid_g/r_ratio_\n Cond787:NaCl_45'\n Cond859:ms221-30\n Cond366:dtt_120_min_dtt-2\n mRLP7:Significant sequence similarity to RPL7B, but neither can fu\nnctionally replace the other. Does not correspond to any rib\nosomal component identified so far, based on its biochemical\n features,,Null mutant is inviable\n Cond690:gal4+gal\n Cond977:F82G_pho4D_1_mM_1NaPP1\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond650:wt_plus_gamma_5_min\n Cond837:tlc1_Expt.2_Passage_9__\n Cond856:pm38-qtop\n mNOP4:RNA recognition motif-containing protein,RNA binding protein\n (putative),Null mutant is inviable; conditional mutant show\ns diminished accumulation of 60S ribosomal subunits due to a\n lack of production of mature 25S rRNA from 27S precursor rR\nNA\n Cond305:Heat_Shock_40_minutes_hs-1\n Cond396:Nitrogen_Depletion_1_h\n Cond658:DES460_(wt)_-_mock_irradiation_-_5_min\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n mYCR016W:Unknown ,, Unknown\n Cond369:1.5_mM_diamide_(5_min)\n Cond552:alpha7\n Cond763:Heat_60'\n mSSF1:putative involvement in mating,Ssf2p homolog,Null mutant is \nviable, ssf1 ssf2 double deletion mutants are inviable. SSF1\n is a high copy suppressor of the mating defect caused by a \ntemperature sensitive G beta subunit mutation. Depletion of \nSSF gene products from growing cultures caused both an arres\nt of cell division and a significant decrease in the ability\n of cells to mate. Mating efficiency was increased by extra \ncopies of the SSF genes and decreased by elimination of the \ngene products\n Cond670:DES459_(mec1)_-_mock_irradiation_-_5_min\n Cond263:ymr269w\n Cond363:dtt_015_min_dtt-2\n Cond782:Peroxide_40'\n mEBP2:EBNA1-binding protein homolog,nucleolar protein,Null mutant \nis inviable\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond414:YPD_6_h_ypd-2\n Cond447:ethanol_vs._reference_pool_car-1\n Cond386:Hypo-osmotic_shock_-_30_min\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond375:1.5_mM_diamide_(60_min)\n Cond967:swi1,_YPD_(c)\n Cond323:heat_shock_29_to_37,_20_minutes\n Cond488:pho85_vs_WT\n Y-Stre.Acid:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond426:YPD_stationary_phase_1_d_ypd-1\n mYOR004W:Unknown ,, Unknown\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n Cond820:tlc1_Expt.1_Passage_1\n Stress.WeakHeat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond934:8h\n Cond322:heat_shock_25_to_37,_20_minutes\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond420:YPD_3_d_ypd-2\n Cond357:2.5mM_DTT_045_min_dtt-1\n Cond379:1M_sorbitol_-_30_min\n Cond758:Heat_0'_(A)\n Cond354:2.5mM_DTT_005_min_dtt-1\n Cond273:yor078w\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond434:DBY7286_37degree_heat_-_20_min\n mYLR003C:Unknown ,, Unknown\n mATC1:interacts with AIP3, localized to the nucleus,,\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond424:YPD_stationary_phase_8_h_ypd-1\n Cond589:cdc15_240\n Cond321:heat_shock_21_to_37,_20_minutes\n Cond783:Peroxide_60'\n mNOC2:NucleOlar Complex 2; involved in nuclear export of pre-ribos\nomes,,\n Cond762:Heat_45'\n SwiSnf.swisnf:Whole-genome expression analysis of snf/swi mutants of Sacch\naromyces cerevisiae. Proc Natl Acad Sci U S A. 2000 Mar 28;\n97(7):3364-9.\n Cond329:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_5_minutes\n Y-Stre.NaCl:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond835:tlc1_Expt.2_Passage_7\n Cond460:17_deg_growth_ct-1\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n Cond359:2.5mM_DTT_090_min_dtt-1\n Cond134:rpl12a\n Cond906:(77i5)_S150-2B_YPD_NormInt\n Cond417:YPD_12_h_ypd-2\n mHPT1:enzyme involved in de novo purine biosynthesis,hypoxanthine \nguanine phosphoribosyltransferase,Null mutant is viable; mut\nants show resistance to 8-azaguanine\n Y-Stre.Sorbitol:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond415:YPD_8_h_ypd-2\n mSPB1:Suppressor of PaB1 mutant; involved in 60S ribosomal subunit\n biogenesis,methyltransferase (putative),Null mutant is invi\nable. The spb1-1 mutant is an extragenic suppressor of a pab\n1 null mutation.\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Calcin.crz1Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond283:KAR2(tetpromoter)\n Cond360:2.5mM_DTT_120_min_dtt-1\n pho.Pho:New components of a system for phosphate accumulation and po\nlyphosphate metabolism in Saccharomyces cerevisiae revealed \nby genomic expression analysis. Mol Biol Cell. 2000 Dec;11(\n12):4309-21.\n mROK1:contains domains found in the DEAD protein family of ATP-dep\nendent RNA helicases; high-copy suppressor of kem1 null muta\nnt,,Null mutant is inviable\n Cond411:diauxic_shift_timecourse_20.5_h\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond543:rst1Drst2Dtec1D/wtlog10(intensity)\n Cond699:gal4-gal\n Cond339:constant_0.32_mM_H2O2_(50_min)_redo\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond938:2h\n Cond858:pm71-30\n Cond641:DES459_(mec1-)_+_0.02%_MMS_-_15_min\n Cond665:mec1_plus_gamma_30_min\n Stress.tempsteady:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mCIC1 mEBP2 mNOC2 mIPI2 mIPI3
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Computational Genomics Lab, Tel-Aviv uniresity