Module number 1123




Database revision : gnsdb28.10
Date : Tue Feb 25 17:36:21 2003
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mLOC1:Localization of mRNA,,Mutant exhibits slow growth at 30C\n Cond914:(99i2)_S150-2B_YPGL+G_NormInt\n mSPC2:subunit of signal peptidase complex, homologous to mammalian\n protein SPC25,signal peptidase complex subunit , similar to\n mammalian protein SPC25,Null mutant is viable. spc1 spc2 do\nuble deletion mutants grow relatively well as compared to wi\nld-type. spc2 sec11 double deletion mutant is inviable. Spc2\np is important for cell viability and signal peptidase activ\nity at high temperatures (42 degrees celsius).\n mRRP7:involved in rRNA processing,,Null mutant is inviable\n mADY4:Hypothetical ORF,,largely forms asci that contain 2 spores (\ndyads) when sporulated\n mPRE6:alpha-type of subunit of 20S proteasome,20S proteasome alpha\n-type subunit,Null mutant is inviable\n Cond912:(99i1)_S150-2B_YPGL_NormInt\n mIST3:U2 snRNP associated protein,,Null mutant is viable but exhib\nits slow growth and a pre-mRNA splicing defect in vivo and i\nn vitro.\n mYGR206W:Unknown ,, Unknown\n mSRP14:Signal recognition particle subunit,,Null mutant is viable\n Cond278:CDC42(tetpromoter)\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n mHMLALPHA2:Homeobox-domain containing protein which, in haploid cells, \nacts with MCM1 to repress a-specific genes. In diploid cells\n alpha2 acts together with a1 to repress transcription of ha\nploid-specific genes.,,\n mYNR024W:Unknown ,, Unknown\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mMED11:14 Kd mediator subunit of RNA polymerase II holoenzyme,RNA p\nolymerase II holoenzyme/mediator subunit 14 kDa,\n Cond640:DES459_(mec1-)_+_0.02%_MMS_-_5_min\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns.  J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond670:DES459_(mec1)_-_mock_irradiation_-_5_min\n Cond906:(77i5)_S150-2B_YPD_NormInt\n Cond256:ymr141c\n Cond904:(77i3)_HBY4_YPGL+G_NormInt\n mVMA22:Required for V-ATPase activity,,Null mutant is viable but is\n defective in vacuolar H(+)-ATPase activity, sensitive to ca\nlcium, cyclosporin A, and FK506, and requires calcineurin fo\nr viability\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mMSG1:Unknown ,, Unknown\n Cond661:DES460_(wt)_-_mock_irradiation_-_90_min\n mYOR305W:Unknown ,, Unknown\n mYNR025C:Unknown ,, Unknown\n mHMRA2:Silenced copy of A2, which encodes a protein of unknown func\ntion.,,\n mVPS63:Unknown ,, Unknown\n mLSM2:Like Sm-D1 protein,snRNA-associated protein, Sm class,Null m\nutant is inviable\n Cond682:MHY1_(crt1)_vs_CRY1_(wild_type)\n mLSM5:Like Sm-E protein,snRNP protein,Null mutant is viable.\n mLSM6:Like Sm-F protein,snRNP protein,Null mutant is viable but gr\nows slowly at 23deg and 30deg, and is required for growth at\n 37deg\n mLSM7:Like Sm-G protein,snRNP protein,Null mutant is viable but gr\nows slowly at 23deg and 30deg, and is required for growth at\n 37deg\n mLSM8:Like Sm-B protein,snRNP protein,Null mutant is inviable\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond905:(77i4)_S150-2B_YPGL+G__NormInt\n mYJR087W:Unknown ,, Unknown\n mYCR095C:Unknown ,, Unknown\n mYKE2:Yeast nuclear gene encoding a protein showing homology to mo\nuse KE2 and containing a putative leucine-zipper motif,bovin\ne NABC complex component homolog , non-native actin binding \ncomplex polypeptide 6 , bovine NABC complex component homolo\ng , non-native actin binding complex polypeptide 6,Null muta\nnt is viable\n mRPC11:TFIIS-like small Pol III subunit C11,TFIIS-like small Pol II\nI subunit C11,Null mutant is inviable\n Cond659:DES460_(wt)_-_mock_irradiation_-_30_min\n mYMR132C:Unknown ,, Unknown\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mPFD1:Prefoldin subunit 1; putative homolog of subunit 1 of bovine\n prefoldin, a chaperone comprised of six subunits,bovine pre\nfoldin subunit 1 homolog (putative),\n Cond672:DES459_(mec1)_-_mock_irradiation_-_60_min\n Cond671:DES459_(mec1)_-_mock_irradiation_-_30_min\n mTOM7:Involved in mitochondrial protein import,translocase of the \nouter mitochondrial membrane,Null mutant is viable\n Cond749: mYOR277C:Unknown ,, Unknown\n mCDC33:Required for START A of cell cycle and sporulation,mRNA cap \nbinding protein eIF-4E,Null mutant is inviable. cdc33 mutant\ns arrest at G(sub)1. cdc33 has normal cAMP pools and is not \nsuppressed by cAPK mutants, suggesting sporulation is indepe\nndent of the cAMP pathway\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n Cond660:DES460_(wt)_-_mock_irradiation_-_60_min\n Cond939:4h\n mBET4:catalyzes prenylation of Ypt1p (as a subunit of PGGTase-II),\ngeranylgeranyltransferase type II alpha subunit (PGGTase-II,\n alpha subunit),\n mLSM2 mLSM6 mLSM5 mLSM8 mLSM7

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Computational Genomics Lab, Tel-Aviv uniresity