Module number 1113




Database revision : gnsdb28.10
Date : Tue Feb 25 17:34:49 2003
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Cond287:2-deoxy-D-glucose\n Cond217:yer050c\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast. Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n mTIM17:Mitochondrial inner membrane protein involved in protein imp\nort,16.5 kDa inner membrane protein required for import of m\nitochondrial precursor proteins,Null mutant is inviable\n Cond912:(99i1)_S150-2B_YPGL_NormInt\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n mYPL144W:Unknown ,, Unknown\n Cond424:YPD_stationary_phase_8_h_ypd-1\n mMRPS18:Unknown ,, Unknown\n mMRPL8:Mitochondrial ribosomal protein MRPL8 (YmL8) (E. coli L17),r\nibosomal protein (YmL8) (E. coli L17),Null mutant is viable;\n shows loss of mitochondrial function, instability of mitoch\nondrial DNA\n mCOX17:Involved in copper metabolism and assembly of cytochrome oxi\ndase,cysteine-rich protein,Null mutant is viable, respirato\nry defective, rescued by addition of copper to growth media \nand/or high copy expression of SCO1 and SCO2 genes\n mMRPL9:Mitochondrial ribosomal protein MRPL9 (YmL9) (E. coli L3) (h\numan MRL3),ribosomal protein (YmL9) (E. coli L3) (human MRL3\n),Null mutant is viable\n mYNR040W:Unknown ,, Unknown\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n mMRPL13:mitochondrial ribosomal protein YmL13,ribosomal protein (YmL\n13),Null mutant is viable, grows poorly on non-fermentable c\narbon sources\n Cond130:rml2(**13)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYOR286W:Unknown ,, Unknown\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n mERV14:ER-derived vesicles,14 kDa protein found on ER-derived vesic\nles,Null mutant is viable but exhibits defects in sporulatio\nn (diploids) and bud site selection (haploids). Null mutants\n also retain the bud site selection marker, Axl2p, in the ER\n and exhibit slow recovery from selective to rich media.\n mYHM1:high copy suppressor of abf2 lacking the HMG1-like mitochond\nrial HM protein; putative mitochondrial carrier protein,,Nul\nl mutant is viable; shm1 abf2 double deletion cannot grow on\n glycerol\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYPR021C:Unknown ,, Unknown\n Cond289:Cycloheximide\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYDR116C:Unknown ,, Unknown\n Cond571:cdc15_50\n Cond943:SK1_YPA\n Cond743: Cond682:MHY1_(crt1)_vs_CRY1_(wild_type)\n mRSM19:mitochondrial ribosome small subunit component,mitochondrial\n ribosome small subunit component,\n Cond:\n mYMR157C:Unknown ,, Unknown\n Cond889:4NQO_2\n Cond942:SK1ume6_YPD\n Cond891:G1MMS\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mCOX8:Cytochrome-c oxidase chain VIII,cytochrome c oxidase chain V\nIII,Null mutant is viable, deficient in cellular respiration\n and cytochrome C oxidase activity\n mMRPL23:mitochondrial ribosomal protein of the large subunit,ribosom\nal protein large subunit,\n Cond948:W303_ume6_YPA_\n Cond937:t=0\n Cond888:MNNG_2\n Cond903:(77i2)_S150-2B_YPGL_NormInt\n mMRPL44:Mitochondrial ribosomal protein MRPL44 (YmL44),ribosomal pro\ntein (YmL44),\n Cond570:cdc15_30\n mSLC1:fatty acyltransferase homologous to E. coli plsC gene; funct\nionally complements plsC mutants,1-acyl-sn-gylcerol-3-phosph\nate acyl transferase (putative),slc1-1 mutant suppresses sph\ningolipid long chain biosynthetic defect; the mutant also ma\nkes novel phosphatidylinositol derivatives and lacks sphingo\nlipids\n mYKR065C:Unknown ,, Unknown\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYGL068W:Unknown ,, Unknown\n Cond893:SMMS\n mTOM22:Translocase of Outer Mitochondrial membrane,mitochondrial im\nport receptor protein,Null mutant is inviable\n Cond466:steady_state_17_dec_C_ct-2\n mTOM7:Involved in mitochondrial protein import,translocase of the \nouter mitochondrial membrane,Null mutant is viable\n mTOM40:Translocase of Outer Mitochondrial membrane,forms the outer \nmembrane import channel , mitochondrial outer membrane prote\nin , forms the outer membrane import channel , mitochondrial\n outer membrane protein,Null mutant is inviable; cells accum\nulate uncleaved mitochondrial precursor proteins\n Cond902:(77i1)_HBY4_YPGL_NormInt\n mISA2:Iron Sulfur Assembly -- IscA/NifA homolog,,null mutant is vi\nable; exhibits dependency on lysine and glutamate for growth\n, an increase in mitochondrial iron concentration, and a res\npiratory deficiency due to accumulation of mutations in mito\nchondrial DNA\n mBET2:Geranylgeranyltransferase Type II beta subunit,geranylgerany\nltransferase type II beta subunit,Null mutant is inviable\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n Stress.tempsteady:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mTOM40 mTOM7 mTOM22
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Computational Genomics Lab, Tel-Aviv uniresity