Module number 1087




Database revision : gnsdb28.10
Date : Tue Feb 25 17:43:02 2003
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mHSP104:involved in thermal and ethanol tolerance, inheritance of [P\nSI+], and reactivation of mRNA splicing after heat shock,hea\nt shock protein 104,Null mutant is viable and defective in i\nnduced thermotolerance\n mYNL134C:Unknown ,, Unknown\n Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n Cond796:Ca5'\n Cond826:tlc1_Expt.1_Passage_7\n Cond399:Nitrogen_Depletion_8_h\n mXKS1:Xylulokinase,xylulokinase,Null mutant is viable and cannot g\nrow on media containing xylulose as the sole carbon source\n mSDH1:flavoprotein subunit of succinate dehydrogenase,succinate de\nhydrogenase flavoprotein subunit,no growth on glycerol (unab\nle to respire)\n mSDH2:Succinate dehydrogenase (ubiquinone) iron-sulfur protein sub\nunit,succinate dehydrogenase (ubiquinone) iron-sulfur protei\nn subunit,Null mutant is viable\n mSET6:Hypothetical ORF,,\n Cond798:Ca30'\n mGDB1:Glycogen debranching enzyme; the enzyme that debranches the \nglycogen having a glucanotranferase + 1-6amyloglucosidase ac\ntivity,,Null mutant is viable but unable to degrade glycogen\n.\n mSDH4:succinate dehydrogenase membrane anchor subunit,succinate de\nhydrogenase membrane anchor subunit,Null mutant is viable, r\netains ability to grow on rich glycerol media\n Cond410:diauxic_shift_timecourse_18.5_h\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n mYOL048C:Unknown ,, Unknown\n Cond675:MHY1_(dun1)_+_heat_20_min\n mYER079W:Unknown ,, Unknown\n Cond981:F82G_pho4D_10_mM_1NaPP1\n Cond362:dtt_000_min__dtt-2\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond400:Nitrogen_Depletion_12_h\n mYIL087C:Unknown ,, Unknown\n Cond834:tlc1_Expt.2_Passage_6\n mYDR391C:Unknown ,, Unknown\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond416:YPD_10_h__ypd-2\n Cond810:Na45'\n Cond637:DES460_+_0.02%_MMS_-_60_min\n mUBC8:Ubiquitin-conjugating enzyme that is able to ubiquitinate hi\nstones in vitro,ubiquitin-conjugating enzyme , ubiquitin-pro\ntein ligase,Null mutant is viable\n mXBP1:DNA-binding transcriptional repressor,transcriptional repres\nsor,Null mutant is viable; overexpression of XBP1 leads to a\n slow-growth phenotype, lengthening of G1, an increase in ce\nll volume, and a repression of G1 cyclin expression\n Cond439:DBY7286_+_0.3_mM_H2O2_(20_min)\n mGPM2:Similar to GPM1 (phosphoglycerate mutase); converts 3-phosph\noglycerate to 2-phosphoglycerate in glycolysis,,Null mutant \nis viable, gpm2 gpm3 double deletion mutants exhibit no synt\nhetic phenotypes\n mYGR052W:Unknown ,, Unknown\n Cond310:Heat_Shock_000_minutes_hs-2\n Cond873:10min\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond429:YPD_stationary_phase_5_d_ypd-1\n Cond318:37C_to_25C_shock_-_60_min\n mYHR097C:Unknown ,, Unknown\n Cond673:DES460_(wild_type)_+_heat_20_min\n Cond155:she4\n mDDR48:DNA damage inducible; implicated in the production or recove\nry of mutations,contains >35 repeats of the amino acid seque\nnce NNNDSYGS , flocculent specific protein,Null mutant is vi\nable, displays reduced spontaneous mutation rate\n Cond312:Heat_Shock_015_minutes_hs-2\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond683:MHY1_(crt1)_vs._CRY1_(wild_type)_-_log_phase\n mICY1:Interacting with the cytoskeleton,,\n mRTN2:Unknown ,, Unknown\n mPYK2:Pyruvate kinase, glucose-repressed isoform,,Null mutant is v\niable and shows no obvious phenotypes; however, a pyk1 pyk2 \ndouble-deletion mutant shows growth defects more pronounced \nthan in the pyk1 mutant strain\n Cond430:YPD_stationary_phase_7_d_ypd-1\n mYMR173W-A:Unknown ,, Unknown\n mYOR161C:Unknown ,, Unknown\n Cond825:tlc1_Expt.1_Passage_6\n mTTR1:Glutaredoxin (thioltransferase) (glutathione reductase),glut\naredoxin , thioltransferase/glutathione reductase,\n mYNL274C:Unknown ,, Unknown\n Cond427:YPD_stationary_phase_2_d_ypd-1\n mYNL194C:Unknown ,, Unknown\n mGLK1:Glucose phosphorylation,glucokinase,Null mutant is viable wi\nth no discernible difference from wild-type; hxk1, hxk2, glk\n1 triple null mutants are unable to grow on any sugar except\n galactose and fail to sporulate\n Cond662:mec1_plus_gamma_5_min\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n mAFR1:coordinates regulation of alpha-factor receptor signalling a\nnd induction of morphogenesis during conjugation,cytoskeleta\nl protein , similar to arrestins,defect in alpha-factor-stim\nulated morphogenesis\n mPRB1:dispensable for haploidization and sporulation, but needed f\nor full protein degradation during sporulation, and proper s\npore morphology,vacuolar protease B,Null mutant is viable, p\nrotease B deficient, has smaller spores than wild-type embed\nded in a thick matrix\n Cond443:DBYyap1_+_0.32_mM_H2O2_(20_min)\n Cond653:wt_plus_gamma_30_min\n Cond314:Heat_Shock_060_minutes__hs-2\n Cond833:tlc1_Expt.2_Passage_5\n mIDH2:NAD+-dependent isocitrate dehydrogenase,NAD-dependent isocit\nrate dehydrogenase,Null mutant is viable\n mMCR1:NADH-cytochrome b5 reductase,NADH-cytochrome b5 reductase,\n mTPO4:Unknown ,, Unknown\n mGRX1:Glutaredoxin,glutaredoxin,Null mutant is viable but sensitiv\ne to oxidative stress. grx1 grx2 null mutants are viable but\n lack heat-stable oxidoreductase activity.\n Cond370:1.5_mM_diamide_(10_min)\n Cond706:gal2gal80-gal\n mNTH1:hydrolyzes trehalose; may be inolved in growth transition fr\nom glucose to glycerol; shows significant sequence similarit\ny to Nth2p,neutral trehalase,Null mutant is viable\n mYMR196W:Unknown ,, Unknown\n mHSP78:Similar to E. coli ClpB protein; involved in folding of some\n mitochondrial proteins,heat shock protein 78,Null mutant is\n viable but in ssc1 mutant background gives rho- phenotype\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYER053C:Unknown ,, Unknown\n mYMR110C:Unknown ,, Unknown\n mYOR285W:Unknown ,, Unknown\n mAUT7:Forms a protein complex with Aut2p to mediate attachment of \nautophagosomes to microtubules. Defective in maturation of t\nhe vacuolar protein, aminopeptidase I,similar to LC3, a micr\notubule-associated protein from rat,Null mutant is viable bu\nt lacks autophagocytosis and is unable to sporulate. AUT7 is\n a suppressor of mutant phenotypes of aut2-1 cells. Uptake o\nf precursor Aminopeptidase I into the vacuole depends on Aut\n2p and Aut7p.\n Cond485:Low-Pi_vs_High-Pi_in_WT_(DBY7286)\n Cond813:Na+FK30'\n Cond303:Heat_Shock_20_minutes_hs-1\n Cond636:DES460_+_0.2%_MMS_-_45_min\n Cond639:DES460_+_0.02%_MMS_-_120_min\n Cond627:DY1457_(wild_type)_3_mM_vs._76_nM_zinc_y12-122\n mAGP2:General amino acid permease with broad substrate specificity\n,amino acid permease,Null mutant is viable; loss of growth o\nn some amino acids as nitrogen source (leu, thr) in a strain\n which has no Gap1p or Agp1p function\n Cond408:diauxic_shift_timecourse_13.5_h\n mYLR356W:Unknown ,, Unknown\n mPRC1:dispensable for haploidization and sporulation, but required\n for full protein degradation during sporulation,carboxypept\nidase Y (proteinase C),Null mutant is viable,proteinase C de\nficient\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n Cond801:CaFK15'\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond332:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_5_minutes\n mYNL305C:Unknown ,, Unknown\n Cond390:aa_starv_0.5_h\n Cond320:heat_shock_17_to_37,_20_minutes\n mTOS5:Hypothetical ORF,,\n Cond316:37C_to_25C_shock_-_30_min\n mIKS1:ira1* kinase suppressor,serine/threonine kinase (putative),N\null mutant is heat shock sensitive\n Cond982:pho85D_10_mM_1NaPP1_\n Cond301:Heat_Shock_10_minutes_hs-1\n mYOL153C:Unknown ,, Unknown\n Calcin.CaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n mYCL042W:Unknown ,, Unknown\n mUIP4:Unknown ,, Unknown\n Cond824:tlc1_Expt.1_Passage_5\n mMSC1:Meiotic Sister-Chromatid recombination,,\n Cond337:constant_0.32_mM_H2O2_(30_min)_redo\n mLAP4:vacuolar aminopeptidase ysc1,vacuolar aminopeptidase ysc1,Le\nucine aminopeptidase deficient\n Cond224:CMD1(tetpromoter)\n mYBR052C:Unknown ,, Unknown\n Cond800:CaFK5'\n mYPC1:Yeast Phyto-ceramidase,alkaline ceramidase with reverse acti\nvity,Null mutant is viable and two times more heat resistant\n than the wild-type parental strain.\n mYET1:Yeast BAP31 homolog,yeast endoplasmic reticulum 25 kDa trans\nmembrane protein,Null mutant is viable\n mPHR1:photolyase,photolyase,photoreactivation repair deficient\n mGTT1:Glutathione Transferase,glutathione transferase,Null mutant \nis viable, heat shock sensitive at stationary phase\n mARO9:aromatic amino acid aminotransferase II,aromatic amino acid \naminotransferase II,Null mutant is viable\n Cond371:1.5_mM_diamide_(20_min)\n Cond651:wt_plus_gamma_10_min\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond832:tlc1_Expt.2_Passage_4\n mNCE102:involved in secretion of proteins that lack classical secret\nory signal sequences,,An uncharacterized allele exhibits def\nects in the export of the mammalian protein galectin-1.\n Cond326:29C_to_33C_-_15_minutes\n Cond855:pm38-30\n Cond638:DES460_+_0.02%_MMS_-_90_min\n mYKL151C:Unknown ,, Unknown\n mYMR315W:Unknown ,, Unknown\n Cond635:DES460_+_0.02%_MMS_-_30_min\n mPAI3:Cytoplasmic inhibitor of proteinase Pep4p,inhibitor of prote\ninase Pep4p,Null mutant is viable but shows increased rate o\nf protein degradation\n mGCY1:Galactose-induced transcript, product is homologous to mamma\nlian aldo/keto reductases, as well as to gamma-crystallin, a\n vertebrate eye lens protein,,Null mutant is viable\n mYJR008W:Unknown ,, Unknown\n mYBR053C:Unknown ,, Unknown\n mYDL124W:Unknown ,, Unknown\n Cond459:YP_sucrose_vs_reference_pool_car-2\n Cond857:pm38-gtoe\n mARA1:D-arabinose dehydrogenase,D-arabinose dehydrogenase,Null mut\nant is viable but cannot produce D-arabinono-1,4-lactone, a \nprecursor of D-erythroascorbic acid\n mYOR121C:Unknown ,, Unknown\n Cond387:Hypo-osmotic_shock_-_45_min\n mMPM1:mitochondrial membrane protein,,\n mYPS6:Gpi-anchored aspartic protease (Yapsin 6),GPI-anchored aspar\ntic protease,\n Cond317:37C_to_25C_shock_-_45_min\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYHR138C:Unknown ,, Unknown\n Cond419:YPD_2_d_ypd-2\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n mSPI1:Stationary Phase Induced; strongly expressed during stationa\nry phase, and trancription is dependent on MSN2/MSN4.,,\n mALD2:Expression induced in response to high osmotic stress. NAD+ \nis preferred coenzyme.,aldeyhde dehydrogenase,ald2 ald3 doub\nle mutants show reduced growth rate with ethanol as the sole\n carbon source.\n Cond882:zero3\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mALD3:Expression induced in response to heat shock, oxidative and \nosmotic stress. NAD+ is preferred coenzyme.,aldehyde dehydro\ngenase,ald2 ald3 double mutants show reduced growth rate wit\nh ethanol as the sole carbon source.\n mSYM1:Unknown ,, Unknown\n mALD4:Glucose repressed. Utilizes NADP+ or NAD+ as a coenzyme equa\nlly well. (sold by SIGMA under the catalogue number A5550, a\nccording to A. Blomberg).,aldehyde dehydrogenase,\n mSOL4:similar to SOL3,,\n mYMR090W:Unknown ,, Unknown\n mYGP1:may be involved in cellular adaptations prior to stationary \nphase,gp37, a glycoprotein synthesized in response to nutrie\nnt limitation which is homologous to the sporulation-specifi\nc SPS100 gene,\n Cond823:tlc1_Expt.1_Passage_4\n mGLO2:Cytoplasmic glyoxylase-II,glyoxylase-II,Null mutant is viabl\ne but shows increased sensitivity to methylglyoxal\n Cond811:Na60'\n mYLR149C:Unknown ,, Unknown\n Cond372:1.5_mM_diamide_(30_min)\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYDR070C:Unknown ,, Unknown\n mYNK1:Nucleoside diphosphate kinase,nucleoside diphosphate kinase,\nNull mutant is viable, exhibits no defects in growth rate, s\npore formation, mating ability, or morphology\n mTPS1:Probable regulator of glucose influx into the cell & into gl\nycolytic pathway, indirectly regulating glucose-induced sign\nalling (activation & inactivation) & initial step(s) of gluc\nose metabolism. Homologue of E. coli otsA protein,trehalose-\n6-phosphate synthase/phosphatase complex 56 kDa synthase sub\nunit,null is viable, but does not grow on glucose and/or fru\nctose,and shows lack of trehalose\n Cond324:heat_shock_33_to_37,_20_minutes\n mTPS2:Trehalose-6-phosphate phosphatase,trehalose-6-phosphate phos\nphatase,Null mutant is viable, exhibits complete loss of tre\nhalose-6-phosphate phosphatase activity, measured in vitro, \nand accumulation of excessive amounts of trehalose-6-phospha\nte instead of trehalose upon heat shock or entrance into sta\ntionary phase in vivo; null mutant is temperature sensitive,\n tps2 (pfk3) pfk1 double mutants are glucose negative\n mGSY1:Highly similar to GSY2. GSY2 is the predominantly expressed \nglycogen synthase,glycogen synthase (UDP-glucose-starch gluc\nosyltransferase),Null mutant is viable. Mutant lacking both \nGSY1 and GSY2 is viable but lacks glycogen synthase activity\n and glycogen deposition\n mGSY2:Highly similar to GSY1. GSY2 is the predominantly expressed \nglycogen synthase. Activity is probably regulated by cAMP-de\npendent and SNF1 protein kinases and type 1 phosphatase,glyc\nogen synthase (UDP-glucose-starch glucosyltransferase),Null \nmutant is viable. Mutant lacking both GSY1 and GSY2 is viabl\ne but lacks glycogen synthase activity and glycogen depositi\non\n mSSA4:member of 70 kDa heat shock protein family,HSP70 family,Null\n mutant is viable; ssa1 ssa2 ssa4 strains are inviable; an i\nntact copy of SSA3 regulated by the constitutive SSA2 promot\ner is capable of rescuing the inviability of an ssa1 ssa2 ss\na4 strain\n Cond380:1M_sorbitol_-_45_min_\n mEMI2:Unknown ,, Unknown\n mYLL023C:Unknown ,, Unknown\n mPNC1:pyrazinamidase and nicotinamidase,nicotinamidase , pyrazinam\nidase,Null mutant is viable\n Cond831:tlc1_Expt.2_Passage_3\n Cond453:YP_ethanol_vs_reference_pool_car-2\n Cond815:Na+FK60'\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n mYMR251W:Unknown ,, Unknown\n mGPD1:glycerol-3-phosphate dehydrogenase,glycerol-3-phosphate dehy\ndrogenase,lethal under conditions of osmotic stress, unable \nto grow on glycerol\n Cond442:DBYyap1-_+_0.3_mM_H2O2_(20_min)\n mYOR289W:Unknown ,, Unknown\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond980:F82G_10_mM_1NaPP1\n Cond979:WT_10_mM_1NaPP1\n Cond307:Heat_Shock_80_minutes_hs-1\n Cond428:YPD_stationary_phase_3_d_ypd-1\n Cond304:Heat_Shock_30_minutes_hs-1\n Cond330:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_15_minutes\n mYBR280C:Unknown ,, Unknown\n mBDH1:Unknown ,, Unknown\n Cond663:mec1_plus_gamma_10_min\n Cond217:yer050c\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond141:rps24a(haploid)\n mYOL083W:Unknown ,, Unknown\n mVPS73:Unknown ,, Unknown\n mTFS1:(putative) lipid binding protein; supressor of a cdc25 mutat\nion,lipid binding protein (putative) , supressor of a cdc25 \nmutation,Null mutant is viable.\n mYMR107W:Unknown ,, Unknown\n Cond388:Hypo-osmotic_shock_-_60_min\n Cond302:Heat_Shock_15_minutes_hs-1\n Cond418:YPD_1_d_ypd-2\n mYHL021C:Unknown ,, Unknown\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n mGGA1:Golgi-localized, gamma-adaptin homology, Arf-binding,ARF-bin\nding protein,\n mYBR230C:Unknown ,, Unknown\n mYSC84:SH3 domain in C-terminus,,Null mutant is viable\n mYNL200C:Unknown ,, Unknown\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mPBI2:Proteinase inhibitor that inhibits protease Prb1p (yscB),pro\nteinase inhibitor I2B (PBI2),Null mutant is viable but shows\n 50% elevation of protein degradation rate when cells are su\nbject to nutritional stress\n mSDP1:Unknown ,, Unknown\n mCVT19:Cytoplasm to Vacuole Targeting; Mutant is defective in impor\nt of aminopeptidase I through the cytoplasm to vacuole targe\nting pathway,Receptor for biosynthetic cytoplasm to vacuole \ntargeting,Null: viable, unable to target vacuolar aminopepti\ndase I and to vacuoles, both under growing and nitrogen star\nvation conditions.\n Cond976:F82G_1_mM_1NaPP1\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond425:YPD_stationary_phase_12_h_ypd-1\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond911:(83i5)_S150-2B_YPD_NormInt\n Cond364:dtt_030_min__dtt-2\n mTSL1:123 kD regulatory subunit of trehalose-6-phosphate synthase/\nphosphatase complex; homologous to TPS3 gene product,similar\n to TPS3 gene product , trehalose-6-phosphate synthase/phosp\nhatase complex 123 kDa regulatory subunit,Null mutant is via\nble\n Cond373:1.5_mM_diamide_(40_min)\n mPST2:Protoplasts-SecreTed protein; the gene product was detected \namong the proteins secreted by regenerating protoplasts,,\n Cond454:YP_fructose_vs_reference_pool_car-2\n Cond822:tlc1_Expt.1_Passage_3\n Cond445:Msn4_overexpression\n Cond409:diauxic_shift_timecourse_15.5_h\n Cond142:rps27b(**11)\n Cond802:CaFK30'\n mGAD1:glutamate decarboxylase,glutamate decarboxylase,\n Cond300:Heat_Shock_05_minutes_hs-1\n Cond814:Na+FK45'\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYLR252W:Unknown ,, Unknown\n mAMS1:vacuolar alpha mannosidase,alpha mannosidase,null mutant is \nviable\n mPEP4:vacuolar proteinase A,vacuolar proteinase A,Null mutant is v\niable, proteinase deficient, phosphatase deficient; pep4 mut\nants exhibit a 60-70% reduction in total protein degradation\n during sporulation\n mYBR056W:Unknown ,, Unknown\n Cond395:Nitrogen_Depletion_30_min.\n mHOR7:hyperosmolarity-responsive gene,,\n Cond553:alpha14\n mUSV1:Up in StarVation,,\n mYGR111W:Unknown ,, Unknown\n mMRF1':May be transcriptional regulator of genes involved in assemb\nly of mitochondrial respiratory proteins,binds to T-rich str\nand of core consensus sequence of autonomously replicating s\nequence,Null mutant is viable but is respiratory-deficient\n mYJL161W:Unknown ,, Unknown\n Cond306:Heat_Shock_60_minutes_hs-1\n mCYC7:iso-2-cytochrome c,iso-2-cytochrome c,Null mutant is viable\n mYOR052C:Unknown ,, Unknown\n Cond797:Ca15'\n mGLC3:Glycogen branching enzyme,1,4-glucan-6-(1,4-glucano)-transfe\nrase,Null mutant is viable, glycogen deficient\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n Cond367:dtt_240_min_dtt-2\n Cond187:vac8\n mCIT1:citrate synthase. Nuclear encoded mitochondrial protein.,cit\nrate synthase,Null mutant is viable; disruption of both CIT1\n and CIT2 result in glutamate auxotrophy and poor growth on \nrich medium containing lactate\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mCIT2:non-mitochondrial citrate synthase,citrate synthase,Null mut\nant is viable; disruption of both CIT1 and CIT2 result in gl\nutamate auxotrophy and poor growth on rich medium containing\n lactate.\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond378:1M_sorbitol_-_15_min\n mPDE1:3',5'-Cyclic-nucleotide phosphodiesterase, low affinity,3',5\n'-cyclic-nucleotide phosphodiesterase, low affinity,Null mut\nant is viable\n mYJL068C:Unknown ,, Unknown\n mGPG1:Unknown ,, Unknown\n mSDS22:Interacts with and may be a positive regulator of GLC7 which\n encodes type1 protein phosphatase,Glc7p regulatory subunit,\nNull mutant is inviable, lethality can be resuced by overexp\nression of GLC7\n Cond413:YPD_4_h_ypd-2\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mSDS24:Similar to S. pombe SDS23, suppresses DIS2, localized to the\n nucleus,,Null mutant is viable\n mYNL115C:Unknown ,, Unknown\n mYLR327C:Unknown ,, Unknown\n Cond374:1.5_mM_diamide_(50_min)\n mRNY1:RiboNuclease from Yeast,ribonuclease, T2 family,\n Cond325:29C_to_33C_-_5_minutes\n Cond809:Na30'\n mYER067W:Unknown ,, Unknown\n Cond859:ms221-30\n mMDH1:mitochondrial malate dehydrogenase,malate dehydrogenase,Null\n mutant is viable\n mYBR269C:Unknown ,, Unknown\n mSSE2:HSP70 family member, highly homologous to Sse1p,HSP70 family\n , SSE1 homolog,Null mutant is viable\n Cond366:dtt_120_min_dtt-2\n mYJL163C:Unknown ,, Unknown\n Cond828:tlc1_Expt.1_Passage_9\n Cond977:F82G_pho4D_1_mM_1NaPP1\n mYOR220W:Unknown ,, Unknown\n mYGR149W:Unknown ,, Unknown\n mYKL091C:Unknown ,, Unknown\n Cond650:wt_plus_gamma_5_min\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n mGPH1:Releases glucose-1-phosphate from glycogen,glycogen phosphor\nylase,Null mutant is viable; haploid cells contain higher le\nvels of intracellular glycogen\n Cond160:sir4\n Cond837:tlc1_Expt.2_Passage_9__\n Cond652:wt_plus_gamma_20_min\n Cond464:37_deg_growth_ct-1\n Cond836:tlc1_Expt.2_Passage_8\n Cond305:Heat_Shock_40_minutes_hs-1\n Cond369:1.5_mM_diamide_(5_min)\n mCTT1:cytoplasmic catalase T,catalase T,Null mutant is viable and \nheat sensitive\n mPGM2:Phosphoglucomutase,phosphoglucomutase,Null mutant is viable,\n pgm1 pgm2 deletion mutants fail to grow on galactose\n mYDR533C:Unknown ,, Unknown\n mHSP12:induced by heat shock, entry into stationary phase, depletio\nn of glucose, and addition of lipids (fatty acids),heat shoc\nk protein 12,Null mutant is viable, but shows induction of h\neat shock response under conditions normally associated with\n low-level HSP12 expression\n Cond363:dtt_015_min_dtt-2\n mYBR139W:Unknown ,, Unknown\n mEMP46:Unknown ,, Unknown\n mECM4:ExtraCellular Mutant,,A Tn3 insertion into this gene causes \nhypersensitivity to the cell surface polymer perturbing agen\nt calcofluor white.\n mYBR241C:Unknown ,, Unknown\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mGPX1:Glutathione peroxidase paralogue,,Null mutant is viable\n Cond414:YPD_6_h_ypd-2\n mDCS1:Unknown ,, Unknown\n mYBL064C:Unknown ,, Unknown\n mDCS2:Unknown ,, Unknown\n Cond386:Hypo-osmotic_shock_-_30_min\n Cond375:1.5_mM_diamide_(60_min)\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond323:heat_shock_29_to_37,_20_minutes\n mTSA2:Unknown ,, Unknown\n Cond426:YPD_stationary_phase_1_d_ypd-1\n Cond344:constant_0.32_mM_H2O2_(160_min)_redo\n Cond759:Heat_0'_(B)\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n Cond820:tlc1_Expt.1_Passage_1\n mAYR1:Subcellular location of Ayr1p: lipid particles and endoplasm\nic reticulum of the yeast,1-acyl dihydroxyacetone phosphate \nreductase,Null mutant is viable\n Stress.WeakHeat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYBR147W:Unknown ,, Unknown\n Cond322:heat_shock_25_to_37,_20_minutes\n mYDL110C:Unknown ,, Unknown\n Cond341:constant_0.32_mM_H2O2_(80_min)_redo\n Cond827:tlc1_Expt.1_Passage_8\n mHSP26:heat shock protein 26,heat shock protein 26,Null mutant is v\niable; hsp26 hsp42 double deletion mutants are viable\n Cond340:constant_0.32_mM_H2O2_(60_min)_redo\n mYDL023C:Unknown ,, Unknown\n Cond379:1M_sorbitol_-_30_min\n mHXK1:Glucose phosphorylation,hexokinase I (PI) (also called hexok\ninase A),Null mutant is viable, is able to ferment fructose,\n and has little or no effect on glucose repression; hxk1, hx\nk2 double null mutant cannot ferment fructose and fails to s\nhow glucose repression at SUC2, CYC1, GAL10\n Cond444:Msn2_overexpression_(repeat)\n Cond151:sbp1\n Cond758:Heat_0'_(A)\n mYBR285W:Unknown ,, Unknown\n Cond434:DBY7286_37degree_heat_-_20_min\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond424:YPD_stationary_phase_8_h_ypd-1\n mDAK1:putative dihydroxyacetone kinase,dihydroxyacetone kinase (pu\ntative),Null mutant is viable and shows no growth defect in \nnormal medium; mutant lacking both dak1 and dak2 is sensitiv\ne to dihydroxyacetone during saline growth\n mUGP1:Uridinephosphoglucose pyrophosphorylase,uridinephosphoglucos\ne pyrophosphorylase,Null mutant is inviable, probably due to\n inability to properly form the cell wall\n Cond321:heat_shock_21_to_37,_20_minutes\n mUGA1:gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate ami\nnotransferase),gamma-aminobutyrate (GABA) transaminase (4-am\ninobutyrate aminotransferase),\n Cond144:rtg1\n mUGA2:involved in utilization of GABA as a nitrogen source,succina\nte semialdehyde dehydrogenase,Null mutant is viable but cann\not grow with GABA as the only nitrogen source.\n mYML131W:Unknown ,, Unknown\n mGLG1:self-glucosylating initiator of glycogen synthesis; similar \nto mammalian glycogenin,glycogen synthesis initiator,Null mu\ntant is viable; disruption of both GLG1 and GLG2 renders cel\nls unable to synthesize glycogen\n mOM45:45-kDa mitochondrial outer membrane protein,45 kDa mitochond\nrial outer membrane protein,Null mutant is viable and shows \nnormal growth, viability, mitochondrial function and mitocho\nndrial protein import\n Cond329:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_5_minutes\n Cond835:tlc1_Expt.2_Passage_7\n mYKL036C:Unknown ,, Unknown\n mYGR043C:Unknown ,, Unknown\n mTPK1:putative catalytic subunit of cAMP-dependent protein kinase,\ncAMP-dependent protein kinase catalytic subunit (putative),m\nulticopy suppression of ras mutant\n Cond417:YPD_12_h_ypd-2\n mTPK2:Involved in nutrient control of cell growth and division,cAM\nP-dependent protein kinase catalytic subunit,Null mutant hap\nloids are defective for invasive growth; diploid homozygous \nnull mutants are defective for pseudohyphal growth.\n Stress.Menadione:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mGRE2:induced by osmotic stress; similar to dihydroflavonol 4-redu\nctase from plants,,\n mGRE3:Induced by osmotic stress; similar to xylose reductase from \nother fungi,,\n mCOX5B:Cytochrome-c oxidase chain Vb,cytochrome c oxidase chain Vb,\nNull mutant is viable\n Cond415:YPD_8_h_ypd-2\n Cond319:37C_to_25C_shock_-_90_min\n mYPL004C:Unknown ,, Unknown\n mYHR087W:Unknown ,, Unknown\n Cond876:zero2\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n pho.Pho:New components of a system for phosphate accumulation and po\nlyphosphate metabolism in Saccharomyces cerevisiae revealed \nby genomic expression analysis. Mol Biol Cell. 2000 Dec;11(\n12):4309-21.\n Cond411:diauxic_shift_timecourse_20.5_h\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond348:1mM_Menadione_(40_min)_redo\n mYJR096W:Unknown ,, Unknown\n mMRP8:mitochondrial ribosomal protein,ribosomal protein,\n mSTF2:ATPase stabilizing factor,ATPase stabilizing factor,\n mYDC1:Yeast dihydro-ceramidase,alkaline dihydroceramidase with min\nor reverse activity,Null mutant is viable.\n mYLR345W:Unknown ,, Unknown\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond339:constant_0.32_mM_H2O2_(50_min)_redo\n mPHM7:Hypothetical ORF,,transcription is regulated by PHO system\n mPHM8:involved in phosphate metabolism,,\n mHSP42:Similar to HSP26; expression is regulated by stress conditio\nns,,Null mutant is viable; hsp42 hsp26 double deletion mutan\nts are viable; hsp42 null mutants subjected to moderate ther\nmal stress reorganize the actin cytoskeleton more slowly tha\nn wild-type\n Cond858:pm71-30\n mPFK26:6-Phosphofructose-2-kinase,6-phosphofructose-2-kinase,Null m\nutant is viable; on pyrvuate medium, no fructose 2,6-P2 is d\netectable in mutant\n mYBR052C mPST2 mTPS1 mTPS2 mTSL1 mYBR139W mYBR280C mPRB1 mNTH1 mDCS1 mAMS1 mLAP4 mCVT19 mTPK1 mTPK2
this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity