Module number 1081




Database revision : gnsdb28.10
Date : Tue Feb 25 17:41:14 2003
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Cond330:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_15_minutes\n Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n Cond796:Ca5'\n Cond826:tlc1_Expt.1_Passage_7\n Cond399:Nitrogen_Depletion_8_h\n mTFS1:(putative) lipid binding protein; supressor of a cdc25 mutat\nion,lipid binding protein (putative) , supressor of a cdc25 \nmutation,Null mutant is viable.\n mSDH2:Succinate dehydrogenase (ubiquinone) iron-sulfur protein sub\nunit,succinate dehydrogenase (ubiquinone) iron-sulfur protei\nn subunit,Null mutant is viable\n Cond798:Ca30'\n mTKL2:transketolase, homologous to tkl1,transketolase, similar to \nTKL1,Null mutant is viable, no reduction in transketolase ac\ntivity. tkl1 tkl2 mutants are auxotrophic for aromatic amino\n acids, indicating a complete block in transketolase activit\ny\n Cond388:Hypo-osmotic_shock_-_60_min\n Cond410:diauxic_shift_timecourse_18.5_h\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response.  Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n Cond302:Heat_Shock_15_minutes_hs-1\n Cond418:YPD_1_d_ypd-2\n Cond675:MHY1_(dun1)_+_heat_20_min\n mYHL021C:Unknown ,, Unknown\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns.  J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond362:dtt_000_min__dtt-2\n Cond981:F82G_pho4D_10_mM_1NaPP1\n mYBR230C:Unknown ,, Unknown\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mSDP1:Unknown ,, Unknown\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond976:F82G_1_mM_1NaPP1\n Cond416:YPD_10_h__ypd-2\n Cond425:YPD_stationary_phase_12_h_ypd-1\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond810:Na45'\n Cond911:(83i5)_S150-2B_YPD_NormInt\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Calcin.NaNa:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond364:dtt_030_min__dtt-2\n Cond373:1.5_mM_diamide_(40_min)\n mYDL222C:Unknown ,, Unknown\n Cond445:Msn4_overexpression\n Cond822:tlc1_Expt.1_Passage_3\n Cond454:YP_fructose_vs_reference_pool_car-2\n Cond802:CaFK30'\n mYOL150C:Unknown ,, Unknown\n Cond300:Heat_Shock_05_minutes_hs-1\n mYGR052W:Unknown ,, Unknown\n Cond814:Na+FK45'\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond805:Ca/Ca+FK30'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n mYLR252W:Unknown ,, Unknown\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mCWP1:cell wall protein, involved in O and N glycosylation, accept\nor of B1-6 glucan.,cell wall mannoprotein,Null mutant is via\nble, has increased sensitivities to calcoflour white and con\ngo red\n mHOR2:RHR2 (GPP1) encodes another DL-glycerol-3-phosphatase,DL-gly\ncerol-3-phosphatase,\n mCWP2:major constituent of the cell wall containing GPI-anchor, pl\nays a role in stabilizing the cell wall, low pH resistance p\nrotein,cell wall mannoprotein,Null mutant is viable, display\ns increased sensitivity to Congo red, calcofluor white, and \nZymolyase\n Cond817:Na/Na+FK45'\n Cond673:DES460_(wild_type)_+_heat_20_min\n mUSV1:Up in StarVation,,\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond312:Heat_Shock_015_minutes_hs-2\n Cond683:MHY1_(crt1)_vs._CRY1_(wild_type)_-_log_phase\n mYHP1:Hypothetical ORF,,\n mCYC1:iso-1-cytochrome c,iso-1-cytochrome c,Cytochrome c deficienc\ny\n mICY1:Interacting with the cytoskeleton,,\n mYJL161W:Unknown ,, Unknown\n Cond807:crz1/Ca30'\n mCYC7:iso-2-cytochrome c,iso-2-cytochrome c,Null mutant is viable\n Cond306:Heat_Shock_60_minutes_hs-1\n Cond804:Ca/Ca+FK15'\n Cond797:Ca15'\n Cond367:dtt_240_min_dtt-2\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae.  Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n mYOR161C:Unknown ,, Unknown\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond385:Hypo-osmotic_shock_-_15_min\n mSCM4:Protein that suppresses ts allele of CDC4 when overexpressed\n,,viable, suppressor of cdc4ts allele\n mYNL274C:Unknown ,, Unknown\n Cond378:1M_sorbitol_-_15_min\n mELO1:elongation enzyme 1, required for the elongation of the satu\nrated fatty acid tetradecanoic acid (14:0) to that of hexade\ncanoic acid (16:0),,Null mutant is viable, but shows no grow\nth on media supplemented with less than 16-C saturated fatty\n acid in a fatty acid synthase minus background\n Cond427:YPD_stationary_phase_2_d_ypd-1\n mYBR116C:Unknown ,, Unknown\n mGPG1:Unknown ,, Unknown\n Cond816:Na/Na+FK30'\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond443:DBYyap1_+_0.32_mM_H2O2_(20_min)\n Cond314:Heat_Shock_060_minutes__hs-2\n Cond27:ckb2\n mTPO4:Unknown ,, Unknown\n Cond374:1.5_mM_diamide_(50_min)\n Cond370:1.5_mM_diamide_(10_min)\n Cond809:Na30'\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYER067W:Unknown ,, Unknown\n mYER053C:Unknown ,, Unknown\n mYHR033W:Unknown ,, Unknown\n mYGR243W:Unknown ,, Unknown\n Calcin.crz1:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond813:Na+FK30'\n Cond303:Heat_Shock_20_minutes_hs-1\n Cond485:Low-Pi_vs_High-Pi_in_WT_(DBY7286)\n Cond627:DY1457_(wild_type)_3_mM_vs._76_nM_zinc_y12-122\n mYNL195C:Unknown ,, Unknown\n mYKL091C:Unknown ,, Unknown\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond160:sir4\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond801:CaFK15'\n Cond390:aa_starv_0.5_h\n Cond464:37_deg_growth_ct-1\n Cond320:heat_shock_17_to_37,_20_minutes\n Cond316:37C_to_25C_shock_-_30_min\n Cond305:Heat_Shock_40_minutes_hs-1\n Cond301:Heat_Shock_10_minutes_hs-1\n Cond982:pho85D_10_mM_1NaPP1_\n Calcin.CaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond369:1.5_mM_diamide_(5_min)\n mPGM2:Phosphoglucomutase,phosphoglucomutase,Null mutant is viable,\n pgm1 pgm2 deletion mutants fail to grow on galactose\n mCTT1:cytoplasmic catalase T,catalase T,Null mutant is viable and \nheat sensitive\n mYCL042W:Unknown ,, Unknown\n mPOT1:peroxisomal 3-oxoacyl CoA thiolase,3-oxoacyl CoA thiolase,Nu\nll mutant is viable, unable to use oleic acid as a carbon so\nurce\n Cond363:dtt_015_min_dtt-2\n Cond800:CaFK5'\n mYPC1:Yeast Phyto-ceramidase,alkaline ceramidase with reverse acti\nvity,Null mutant is viable and two times more heat resistant\n than the wild-type parental strain.\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond414:YPD_6_h_ypd-2\n mDCS1:Unknown ,, Unknown\n mYBL064C:Unknown ,, Unknown\n Cond386:Hypo-osmotic_shock_-_30_min\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond371:1.5_mM_diamide_(20_min)\n Cond377:1M_sorbitol_-_5_min\n Cond323:heat_shock_29_to_37,_20_minutes\n mYDR134C:Unknown ,, Unknown\n Cond808:Na15'\n Cond651:wt_plus_gamma_10_min\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mNCE102:involved in secretion of proteins that lack classical secret\nory signal sequences,,An uncharacterized allele exhibits def\nects in the export of the mammalian protein galectin-1.\n Cond326:29C_to_33C_-_15_minutes\n Cond855:pm38-30\n Cond426:YPD_stationary_phase_1_d_ypd-1\n mYKL151C:Unknown ,, Unknown\n mCCW12:Hypothetical ORF,cell wall mannoprotein,Null mutant is viabl\ne and shows decrease in mating efficiency and defect in aggl\nutination\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n Stress.WeakHeat:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond322:heat_shock_25_to_37,_20_minutes\n mYDL110C:Unknown ,, Unknown\n Cond459:YP_sucrose_vs_reference_pool_car-2\n mYDL023C:Unknown ,, Unknown\n Cond379:1M_sorbitol_-_30_min\n Cond449:glucose_vs._reference_pool_car-1\n Cond387:Hypo-osmotic_shock_-_45_min\n mHXK1:Glucose phosphorylation,hexokinase I (PI) (also called hexok\ninase A),Null mutant is viable, is able to ferment fructose,\n and has little or no effect on glucose repression; hxk1, hx\nk2 double null mutant cannot ferment fructose and fails to s\nhow glucose repression at SUC2, CYC1, GAL10\n Cond444:Msn2_overexpression_(repeat)\n Cond151:sbp1\n Cond758:Heat_0'_(A)\n mSTL1:sugar transporter-like protein,sugar transporter-like protei\nn,Null mutant is viable, no growth defects on galactose, man\nnose, maltose, or glycerol.\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond317:37C_to_25C_shock_-_45_min\n Cond434:DBY7286_37degree_heat_-_20_min\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYHR138C:Unknown ,, Unknown\n mGNP1:high-affinity glutamine permease,high affinity glutamine per\nmease,Null mutant is viable but shows reduced glutamine tran\nsport and is therefore resistant to the glutamine analog L-g\nlutamic acid gamma-monohydroxamate; overexpression induces s\nensitivity to heat shock\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond419:YPD_2_d_ypd-2\n Cond321:heat_shock_21_to_37,_20_minutes\n Cond144:rtg1\n mACO1:Aconitase, mitochondrial,aconitase,glutamate auxotrophy\n mOM45:45-kDa mitochondrial outer membrane protein,45 kDa mitochond\nrial outer membrane protein,Null mutant is viable and shows \nnormal growth, viability, mitochondrial function and mitocho\nndrial protein import\n Cond329:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_5_minutes\n mSPI1:Stationary Phase Induced; strongly expressed during stationa\nry phase, and trancription is dependent on MSN2/MSN4.,,\n Cond456:YP_glucose_vs_reference_pool_car-2\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mALD2:Expression induced in response to high osmotic stress. NAD+ \nis preferred coenzyme.,aldeyhde dehydrogenase,ald2 ald3 doub\nle mutants show reduced growth rate with ethanol as the sole\n carbon source.\n mSOL1:Multicopy Suppressor Of los1,,Null mutant is viable\n mALD4:Glucose repressed. Utilizes NADP+ or NAD+ as a coenzyme equa\nlly well. (sold by SIGMA under the catalogue number A5550, a\nccording to A. Blomberg).,aldehyde dehydrogenase,\n mSOL4:similar to SOL3,,\n mYMR090W:Unknown ,, Unknown\n Cond417:YPD_12_h_ypd-2\n mYGP1:may be involved in cellular adaptations prior to stationary \nphase,gp37, a glycoprotein synthesized in response to nutrie\nnt limitation which is homologous to the sporulation-specifi\nc SPS100 gene,\n Cond806:crz1/Ca15'\n mGRE1:Induced by osmotic stress,,Null mutant is viable and shows n\no phenotype in osmotic, ionic or oxidative stress\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mGRE2:induced by osmotic stress; similar to dihydroflavonol 4-redu\nctase from plants,,\n mGRE3:Induced by osmotic stress; similar to xylose reductase from \nother fungi,,\n mCOX5B:Cytochrome-c oxidase chain Vb,cytochrome c oxidase chain Vb,\nNull mutant is viable\n Cond415:YPD_8_h_ypd-2\n Cond319:37C_to_25C_shock_-_90_min\n mDDR2:DNA Damage Responsive,,Null mutant is viable, shows no defec\nt in heat shock recovery or thermotolerance and appear norma\nl for DNA damage sensitivity and mutagenesis\n mFSH1:Unknown ,, Unknown\n Cond811:Na60'\n mYHR087W:Unknown ,, Unknown\n Cond372:1.5_mM_diamide_(30_min)\n mYJL144W:Unknown ,, Unknown\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYDR070C:Unknown ,, Unknown\n Cond324:heat_shock_33_to_37,_20_minutes\n mTPS1:Probable regulator of glucose influx into the cell & into gl\nycolytic pathway, indirectly regulating glucose-induced sign\nalling (activation & inactivation) & initial step(s) of gluc\nose metabolism. Homologue of E. coli otsA protein,trehalose-\n6-phosphate synthase/phosphatase complex 56 kDa synthase sub\nunit,null is viable, but does not grow on glucose and/or fru\nctose,and shows lack of trehalose\n mTPS2:Trehalose-6-phosphate phosphatase,trehalose-6-phosphate phos\nphatase,Null mutant is viable, exhibits complete loss of tre\nhalose-6-phosphate phosphatase activity, measured in vitro, \nand accumulation of excessive amounts of trehalose-6-phospha\nte instead of trehalose upon heat shock or entrance into sta\ntionary phase in vivo; null mutant is temperature sensitive,\n tps2 (pfk3) pfk1 double mutants are glucose negative\n pho.Pho:New components of a system for phosphate accumulation and po\nlyphosphate metabolism in Saccharomyces cerevisiae revealed \nby genomic expression analysis.  Mol Biol Cell. 2000 Dec;11(\n12):4309-21.\n mGSY2:Highly similar to GSY1. GSY2 is the predominantly expressed \nglycogen synthase. Activity is probably regulated by cAMP-de\npendent and SNF1 protein kinases and type 1 phosphatase,glyc\nogen synthase (UDP-glucose-starch glucosyltransferase),Null \nmutant is viable. Mutant lacking both GSY1 and GSY2 is viabl\ne but lacks glycogen synthase activity and glycogen depositi\non\n mPUT4:putative proline-specific permease,proline-specific permease\n (putative),inability to use proline as a nitrogen source\n Cond380:1M_sorbitol_-_45_min_\n mSIP18:Salt-Induced Protein,,Null mutant is viable.\n Cond411:diauxic_shift_timecourse_20.5_h\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mEMI2:Unknown ,, Unknown\n mPNC1:pyrazinamidase and nicotinamidase,nicotinamidase , pyrazinam\nidase,Null mutant is viable\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond815:Na+FK60'\n mGPD1:glycerol-3-phosphate dehydrogenase,glycerol-3-phosphate dehy\ndrogenase,lethal under conditions of osmotic stress, unable \nto grow on glycerol\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast.  Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond274:yor080w(**3)\n Cond339:constant_0.32_mM_H2O2_(50_min)_redo\n mPHM7:Hypothetical ORF,,transcription is regulated by PHO system\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n mHSP42:Similar to HSP26; expression is regulated by stress conditio\nns,,Null mutant is viable; hsp42 hsp26 double deletion mutan\nts are viable; hsp42 null mutants subjected to moderate ther\nmal stress reorganize the actin cytoskeleton more slowly tha\nn wild-type\n Cond980:F82G_10_mM_1NaPP1\n Cond858:pm71-30\n Cond514:GAL-STE12,3hrs.gallog10(intensity)\n Cond304:Heat_Shock_30_minutes_hs-1\n Cond428:YPD_stationary_phase_3_d_ypd-1\n mTPS1 mTPS2

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Computational Genomics Lab, Tel-Aviv uniresity