Module number 1063




Database revision : gnsdb28.10
Date : Tue Feb 25 17:38:34 2003
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Cond330:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_15_minutes\n Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n Cond755: Cond498:wtħ500nMaF,30minlog10(intensity)\n Cond912:(99i1)_S150-2B_YPGL_NormInt\n Cond541:fus3D+50nMaF,30min/wtlog10(intensity)\n Cond494:wtħ5nMaF,30minlog10(intensity)\n Cond565:alpha98\n Cond548:cln3-2\n Cond751: Cond675:MHY1_(dun1)_+_heat_20_min\n Cond13:ase1(**12)\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond533:fus3D+50nMaF/wt+50nMaF,30minlog10(intensity)\n Cond735: mHHO1:Histone H1,histone H1,Null mutant is viable; other phenotype\n: Increased basal expression of a CYC1-lacz reporter gene; n\nuclear localization of a Hho1-GFP fusion protein\n mYBR070C:Unknown ,, Unknown\n Cond579:cdc15_140\n Cond556:alpha35\n mMNN1:Alpha-1,3-mannosyltransferase,alpha-1,3-mannosyltransferase,\nNull mutant is viable\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond505:wtħ50nMaF,120minlog10(intensity)\n Cond916:(99i5)__HBY4_YPGL+G_NormInt\n Cond562:alpha77\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond805:Ca/Ca+FK30'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond568:alpha119\n mYPL267W:Unknown ,, Unknown\n Cond279:ERG11(tetpromoter)\n Cond553:alpha14\n Cond752: Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n mYHP1:Hypothetical ORF,,\n Cond749: Cond902:(77i1)_HBY4_YPGL_NormInt\n Cond216:yer044c(haploid)\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond569:cdc15_10\n Cond807:crz1/Ca30'\n Cond580:cdc15_150\n Cond804:Ca/Ca+FK15'\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond481:WT+/-100mM3AT(SetB)(491)\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond581:cdc15_160\n Cond54:erg3(haploid)\n Cond558:alpha49\n Cond572:cdc15_70\n Cond734: Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond582:cdc15_170\n Cond653:wt_plus_gamma_30_min\n Cond314:Heat_Shock_060_minutes__hs-2\n mPOL30:Accessory factor for DNA polymerase delta, mRNA increases in\n G1, peaks in S in mitosis, & increases prior to DNA synthes\nis in meiosis; required for DNA replication & repair, requir\ned for viability in cdc44, rad50, rad52 or rad57 backgrounds\n,,Null mutant is inviable\n Cond571:cdc15_50\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond965:ndt80_delete_mid_g/r_ratio_\n Cond583:cdc15_180\n Cond737: Cond742: Cond754: Calcin.crz1:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond555:alpha28\n Cond493:wtħ1.5nMaF,30minlog10(intensity)\n Cond813:Na+FK30'\n Cond903:(77i2)_S150-2B_YPGL_NormInt\n mSVS1:involved in vanadate resistance,,Null mutant is viable, show\ns increased sensitivity to vanadate, but not other metallic \nions or drugs\n Cond570:cdc15_30\n Cond627:DY1457_(wild_type)_3_mM_vs._76_nM_zinc_y12-122\n mRNR1:ribonucleotide reductase,ribonucleotide reductase, large (R1\n) subunit,Null mutant is inviable\n Cond503:wtħ50nMaF,60minlog10(intensity)\n Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Cond564:alpha91\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n Cond750: Cond510:fus3Dħ50nMaF,30minlog10(intensity)\n Cond652:wt_plus_gamma_20_min\n Cond547:cln3-1\n mMCD1:Mitotic Chromosome Determinant; similar to S. pombe RAD21; m\nay function in chromosome morphogenesis from S phase through\n mitosis,,Null mutant is inviable; temperature sensitive mut\nants are defective in mitotic sister chromatid cohesion and \nmitotic chromosome condensation; multicopy suppressor of smc\n1-2 mutation\n mAXL2:involved in polarity establishment/cellular polarization dur\ning budding,,AXL2 can serve as a multicopy suppressor of rho\n3 and is required for the haploid axial budding pattern of S\n. cerevisiae.\n mTOS4:Hypothetical ORF,,\n Cond500:wtħ50nMaF,15minlog10(intensity)\n Cond552:alpha7\n Cond29:clb2\n Cond654:wt_plus_gamma_45_min\n Cond224:CMD1(tetpromoter)\n Cond504:wtħ50nMaF,90minlog10(intensity)\n Cond561:alpha70\n Cond519:rst1Drst2Dħ50nMaF,30minlog10(intensity)\n Cond15:bim1(**15)\n Cond745: Cond124:rad6(haploid)\n Cond377:1M_sorbitol_-_5_min\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond53:erg2\n Cond651:wt_plus_gamma_10_min\n Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n Cond739: Cond496:wtħ50nMaF,30minlog10(intensity)\n mCLN1:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest\n Cond748: mCLN2:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest; dominant mutation advances the G(sub)1- to\n S- phase transition and impairs ability of cells to arrest \nin G(sub)1 phase in response to external signals\n Cond587:cdc15_220\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n mCSI2:chitin synthase involved,chitin synthase 3 complex structura\nl component (putative),Null mutant is viable but shows deloc\nalized chitin deposition\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond379:1M_sorbitol_-_30_min\n Cond550:clb2-1\n mHHT1:Histone H3 (HHT1 and HHT2 code for identical proteins),histo\nne H3 (HHT1 and HHT2 code for identical proteins),Null mutan\nt is viable\n Cond557:alpha42\n mHHT2:Histone H3 (HHT1 and HHT2 code for identical proteins),histo\nne H3 (HHT1 and HHT2 code for identical proteins),\n mYBR089W:Unknown ,, Unknown\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Cond434:DBY7286_37degree_heat_-_20_min\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond333:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_15_minutes\n Cond502:wtħ50nMaF,45minlog10(intensity)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond563:alpha84\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n Cond666:mec1_plus_gamma_45_min\n mCDC21:cell division cycle blocked at 36 degree C,thymidylate synth\nase,defective in continued replication during S phase of the\n cell cycle; temperature-sensitive thymidylate auxotroph\n Cond175:swi4\n Cond806:crz1/Ca15'\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mHTA1:Histone H2A (HTA1 and HTA2 code for nearly identical protein\ns),histone H2A (HTA1 and HTA2 code for nearly identical prot\neins),Null mutant is viable\n Cond250:ymr031w-a\n Cond501:wt+/-50nMaF,30minlog10(intensity)\n Cond319:37C_to_25C_shock_-_90_min\n mHTA2:Histone H2A (HTA1 and HTA2 code for nearly identical protein\ns),histone H2A (HTA1 and HTA2 code for nearly identical prot\neins),Null mutant is viable. Deletion of the HTA2-HTB2 (TRT2\n) locus has no reported observable phenotypes, presumably be\ncause HTA1-HTB1 (TRT1) expression is upregulated and can com\npensate in the absence of TRT2. Overexpression of TRT2 can s\nuppress Ty insertion mutations\n Cond284:PMA1(tetpromoter)\n Cond153:sgs1\n Cond554:alpha21\n Cond398:Nitrogen_Depletion_4_h\n Cond738:90\n mHHF1:Histone H4 (HHF1 and HHF2 code for identical proteins),histo\nne H4 (HHF1 and HHF2 code for identical proteins),\n Cond575:cdc15_100\n Cond732:fkh1,2_alpha_factor_000_min_y12n57\n mHHF2:Histone H4 (HHF1 and HHF2 code for identical proteins),histo\nne H4 (HHF1 and HHF2 code for identical proteins),\n Cond294:Itraconazole\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond747: Cond497:wtħ158nMaF,30minlog10(intensity)\n Cond560:alpha63\n Cond576:cdc15_110\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond559:alpha56\n mSRL1:Suppressor of rad53 lethality,,\n Cond514:GAL-STE12,3hrs.gallog10(intensity)\n Cond577:cdc15_120\n Cond428:YPD_stationary_phase_3_d_ypd-1\n Cond304:Heat_Shock_30_minutes_hs-1\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n mHTB1:Histone H2B (HTB1 and HTB2 code for nearly identical protein\ns),histone H2B (HTB1 and HTB2 code for nearly identical prot\neins),Null mutant is viable\n Cond551:alpha0\n Cond549:clb2-2\n mHTB2:Histone H2B (HTB1 and HTB2 code for nearly identical protein\ns),histone H2B (HTB1 and HTB2 code for nearly identical prot\neins),Null mutant is viable. Deletion of the HTA2-HTB2 (TRT2\n) locus has no reported observable phenotypes, presumably be\ncause HTA1-HTB1 (TRT1) expression is upregulated and can com\npensate in the absence of TRT2\n mYOX1:Homeodomain protein that binds leu-tRNA gene,homeobox-domain\n containing protein,Null mutant is viable\n mHHF1 mHHT1 mHTA1 mHHT2 mHHF2 mHTB1
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Computational Genomics Lab, Tel-Aviv uniresity