Module number 1052




Database revision : gnsdb28.10
Date : Tue Feb 25 17:36:33 2003
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mYDL199C:Unknown ,, Unknown\n Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n mGUT1:Glycerol utilization,converts glycerol to glycerol-3-phospha\nte , glyerol kinase,Null mutant is viable but is unable to g\nrow on glycerol\n mYPL201C:Unknown ,, Unknown\n mGAC1:Regulatory subunit for phosphoprotein phosphatase type 1 (PP\n-1), also known as Glc7p, which regulates glycogen synthase-\n2,Glc7p regulatory subunit,Reduced glycogen accumulation\n PEX.Pex:Transcriptome profiling to identify genes involved in peroxi\nsome assembly and function. J Cell Biol. 2002 Jul 22;158(2)\n:259-71.\n mYPR015C:Unknown ,, Unknown\n Cond163:ssn6(haploid)\n Cond698:gal3-gal\n mTFS1:(putative) lipid binding protein; supressor of a cdc25 mutat\nion,lipid binding protein (putative) , supressor of a cdc25 \nmutation,Null mutant is viable.\n mSIP4:Possibly involved in Snf1p regulated transcriptional activat\nion,,\n Cond432:YPD_stationary_phase_22_d_ypd-1\n mYMR107W:Unknown ,, Unknown\n Cond410:diauxic_shift_timecourse_18.5_h\n mYPL280W:Unknown ,, Unknown\n Cond418:YPD_1_d_ypd-2\n mYAT2:The Yat2p protein shows significant homology with the known \ncarnitine acetyltransferase associated with the outer-mitoch\nondrial membrane, Yat1p, and also functions as a carnitine a\ncetyltransferase.,carnitine acetyltransferase,Null: viable. \nOther phenotypes: The cit2yat2 double mutant does not grow o\nn ethanol, glycerol and acetate in the presence of carnitine\n.\n mYHL021C:Unknown ,, Unknown\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond362:dtt_000_min__dtt-2\n mDIT1:Disp. for spores & spore viability - required for dityrosine\n accumul. in the outer spore wall (s.w.), s.w. maturation & \nresist. to ether & lytic enzymes. Spore-autonomous function \nin heterozygotes. mRNA is trans. mid/late in s.w. formation,\nfirst enzyme in dityrosine synthesis in the outer layer of t\nhe spore wall pathway, converting L-tyrosine to N-formyl-L-t\nyrosine,lack outermost layer of spore wall\n mYBR230C:Unknown ,, Unknown\n Cond730:hda1\n Cond834:tlc1_Expt.2_Passage_6\n Cond697:gal2-gal\n mPBI2:Proteinase inhibitor that inhibits protease Prb1p (yscB),pro\nteinase inhibitor I2B (PBI2),Null mutant is viable but shows\n 50% elevation of protein degradation rate when cells are su\nbject to nutritional stress\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mCYB2:Expression is repressed by glucose and anaerobic conditions,\n is induced by L-lactate and is regulated by GRR1, ROX3, HAP\n1, HXK2 and CYC8,L-lactate cytochrome c oxidoreductase , cyt\nochrome b2,Null mutant is viable but is deficient in cytochr\nome b2 and L-lactate dehydrogenase activity and is unable to\n use L-lactate as a sole carbon source\n Cond467:steady_state_21_dec_C_ct-2\n Cond416:YPD_10_h__ypd-2\n Cond425:YPD_stationary_phase_12_h_ypd-1\n Cond911:(83i5)_S150-2B_YPD_NormInt\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYGR067C:Unknown ,, Unknown\n Cond364:dtt_030_min__dtt-2\n Cond445:Msn4_overexpression\n Cond454:YP_fructose_vs_reference_pool_car-2\n mSFC1:succinate-fumarate carrier,succinate-fumarate transport prot\nein,\n Cond702:gal7-gal\n Cond696:gal1-gal\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond429:YPD_stationary_phase_5_d_ypd-1\n Cond701:gal6-gal\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond404:Nitrogen_Depletion_5_d\n Cond689:gal3+gal\n Cond452:sucrose_vs._reference_pool_car-1\n Cond693:gal7+gal\n mYEL070W:Unknown ,, Unknown\n mSGA1:intracellular sporulation-specific glucoamylase involved in \nglycogen degradation. Induced during starvation of a/a late \nin sporulation, but dispensable for sporulation,glucoamylase\n,suppression of growth arrest of cdc25\n Cond694:gal10+gal\n Cond430:YPD_stationary_phase_7_d_ypd-1\n mYNR073C:Unknown ,, Unknown\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n Cond700:gal5-gal\n Cond88:isw1,isw2\n Cond688:gal2+gal\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mCIT3:Mitochondrial isoform of citrate synthase,citrate synthase,N\null mutant shows severely reduced growth on the respiratory \nsubstrate glycerol in a delta cit1 background\n Cond692:gal6+gal\n Cond385:Hypo-osmotic_shock_-_15_min\n mACS1:one of 2 acetyl-coA synthetases in yeast,acetyl CoA syntheta\nse,Null mutant is viable and grows on ethanol or glucose (bu\nt not acetate) as sole carbon source (but with long lag-phas\ne); acs1 acs2 double null mutant is inviable\n mYLR312C:Unknown ,, Unknown\n mJEN1:Repressed by glucose, induced by lactic acid; in high copy, \nweakly suppresses cpr3 null mutan phenotype on lactate mediu\nm at 37 degrees,carboxylic acid transporter protein homolog,\ndeletion results in slow growth of yeast in synthetic medium\n supplemented with L-lactate and synergistic with cpr3 null \nmutation; essential for lactate uptake in yeast\n Cond427:YPD_stationary_phase_2_d_ypd-1\n mYNL194C:Unknown ,, Unknown\n mBOP2:bypass of PAM1,,\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mFBP1:fructose-1,6-bisphosphatase,fructose-1,6-bisphosphatase,unab\nle to grow with ethanol\n Cond314:Heat_Shock_060_minutes__hs-2\n mECM13:ExtraCellular Mutant,,A Tn3 insertion into this gene causes \nhypersensitivity to the cell surface polymer perturbing agen\nt calcofluor white.\n mYLR327C:Unknown ,, Unknown\n Cond731:hda1 \n Cond433:YPD_stationary_phase_28_d_ypd-1\n mALP1:Homologous to permeases Can1p and Lyp1p,basic amino acid per\nmease,\n mYFL051C:Unknown ,, Unknown\n mYLL055W:Unknown ,, Unknown\n mYGR243W:Unknown ,, Unknown\n Cond845:expt8\n Cond690:gal4+gal\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n Cond970:swi1,_minimal_(c)\n Cond627:DY1457_(wild_type)_3_mM_vs._76_nM_zinc_y12-122\n mYNL195C:Unknown ,, Unknown\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mADY2:Accumulation of DYads,,Null mutant is viable; forms predomin\nantly asci containing 2 spores (dyads) whensporulated; requi\nred for long-term growth on YPD at 37 degrees C.\n mHAP4:Regulates respiratory functions; encodes divergent overlappi\nng transcripts,transcriptional activator protein of CYC1 (co\nmponent of HAP2/HAP3 heteromer),\n mREG2:Possible regulatory subunit for the PP1 family protein phosp\nhatase Glc7p,,Null mutant is viable; reg1 reg2 double mutant\ns exhibit a severe growth defect (suppressed by loss-of-func\ntion mutation in snf1); overexpression of REG2 complements s\nlow-growth defect of a reg1 mutant but not the defects in gl\nycogen accumulation or glucose repression\n Cond320:heat_shock_17_to_37,_20_minutes\n mCRC1:carnitine carrier,carnitine transporter,Null mutant is viabl\ne\n mYBR051W:Unknown ,, Unknown\n mPXA1:Pxa1p and Pxa2p appear to be subunits of a peroxisomal ATP-b\ninding cassette transporter necessary for transport of long-\nchain fatty acids into peroxisomes,ABC transporter of long-c\nhain fatty acids,Null mutant is viable but cannot grow on me\ndia with oleic acid as sole carbon source\n mSPG1:Hypothetical ORF,,Null mutant is viable; SPG1 is required fo\nr long-term survival in YPD at 37 degrees C.\n mDIA3:involved in invasive and pseudohyphal growth,,Null mutant is\n viable and causes invasive growth in haploids and pseudohyp\nhal growth in diploids\n mHSP12:induced by heat shock, entry into stationary phase, depletio\nn of glucose, and addition of lipids (fatty acids),heat shoc\nk protein 12,Null mutant is viable, but shows induction of h\neat shock response under conditions normally associated with\n low-level HSP12 expression\n Cond363:dtt_015_min_dtt-2\n mECM4:ExtraCellular Mutant,,A Tn3 insertion into this gene causes \nhypersensitivity to the cell surface polymer perturbing agen\nt calcofluor white.\n mMAL11:Part of MAL1 complex locus; encodes funct. maltose permease \nin all strains, exhibits sign. seq. variability; shows homol\n. to functional maltose permease from S. carlsbergenesis; me\nmber of the 12 tm domain superfamily of sugar transporters,a\nlpha-glucoside transporter , hexose transporter , maltose pe\nrmease,Mutant is defective in maltose fermentation.\n mMAL12:Part of the complex locus MAL1; functional in S288C,maltase,\nDefective maltose fermentation\n mYFL030W:Unknown ,, Unknown\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYMR322C:Unknown ,, Unknown\n Cond414:YPD_6_h_ypd-2\n Cond447:ethanol_vs._reference_pool_car-1\n mYBL064C:Unknown ,, Unknown\n mDCS2:Unknown ,, Unknown\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYFL052W:Unknown ,, Unknown\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYKL187C:Unknown ,, Unknown\n Cond426:YPD_stationary_phase_1_d_ypd-1\n Cond457:YP_mannose_vs_reference_pool_car-2\n mYMR206W:Unknown ,, Unknown\n mYBR147W:Unknown ,, Unknown\n Cond705:gal1gal10+gal\n Cond459:YP_sucrose_vs_reference_pool_car-2\n Cond420:YPD_3_d_ypd-2\n Cond857:pm38-gtoe\n mHSP26:heat shock protein 26,heat shock protein 26,Null mutant is v\niable; hsp26 hsp42 double deletion mutants are viable\n Cond449:glucose_vs._reference_pool_car-1\n Cond387:Hypo-osmotic_shock_-_45_min\n mPCK1:phosphoenolpyruvate carboxylkinase,phosphoenolpyruvate carbo\nxylkinase,Null mutant is viable.\n mHXK1:Glucose phosphorylation,hexokinase I (PI) (also called hexok\ninase A),Null mutant is viable, is able to ferment fructose,\n and has little or no effect on glucose repression; hxk1, hx\nk2 double null mutant cannot ferment fructose and fails to s\nhow glucose repression at SUC2, CYC1, GAL10\n mYPR150W:Unknown ,, Unknown\n mSTL1:sugar transporter-like protein,sugar transporter-like protei\nn,Null mutant is viable, no growth defects on galactose, man\nnose, maltose, or glycerol.\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond87:isw1\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond450:mannose_vs._reference_pool__car-1\n Cond871:yhe710-ss\n Cond419:YPD_2_d_ypd-2\n Cond844:expt7\n Cond431:YPD_stationary_phase_13_d_ypd-1\n SwiSnf.swisnf:Whole-genome expression analysis of snf/swi mutants of Sacch\naromyces cerevisiae. Proc Natl Acad Sci U S A. 2000 Mar 28;\n97(7):3364-9.\n mYPR151C:Unknown ,, Unknown\n mNDE2:Unknown ,, Unknown\n mYOR186W:Unknown ,, Unknown\n mSPI1:Stationary Phase Induced; strongly expressed during stationa\nry phase, and trancription is dependent on MSN2/MSN4.,,\n Cond456:YP_glucose_vs_reference_pool_car-2\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond640:DES459_(mec1-)_+_0.02%_MMS_-_5_min\n mYGR043C:Unknown ,, Unknown\n mSOL4:similar to SOL3,,\n Cond417:YPD_12_h_ypd-2\n mUGX2:Product of gene unknown,,\n mGRE1:Induced by osmotic stress,,Null mutant is viable and shows n\no phenotype in osmotic, ionic or oxidative stress\n Cond403:Nitrogen_Depletion_3_d\n mACH1:Mannose-containing glycoprotein which binds concanavalin A,a\ncetyl CoA hydrolase,\n Cond415:YPD_8_h_ypd-2\n mMAL32:Part of the complex locus MAL3; functional in S288C; highly \nhomologous to MAL62 from S. carlsbergenesis strain CB11,malt\nase,Defective maltose fermentation\n Cond685:wt-gal\n Cond182:tup1(haploid)\n mMAL33:Part of complex locus MAL3; nonfunctional in S288C, shows ho\nmology to both functional & nonfunctional MAL-activator prot\neins in other Sc strains & to other nonfunctional MAL-activa\ntor sequences from S288C (i.e. MAL33, YPR196W, & YFL052W),MA\nL-activator protein,Defective maltose fermentation\n Cond402:Nitrogen_Depletion_2_d\n mYHR087W:Unknown ,, Unknown\n mYLR149C:Unknown ,, Unknown\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mPHO89:Probable Na+/Pi symporter,Na+/Pi symporter (putative),Null m\nutant is viable\n Cond401:Nitrogen_Depletion_1_d\n mPUT1:proline oxidase,proline oxidase,inability to use proline as \na nitrogen source\n mGSY1:Highly similar to GSY2. GSY2 is the predominantly expressed \nglycogen synthase,glycogen synthase (UDP-glucose-starch gluc\nosyltransferase),Null mutant is viable. Mutant lacking both \nGSY1 and GSY2 is viable but lacks glycogen synthase activity\n and glycogen deposition\n mISF1:May regulate NAM7 function, possibly at level of mRNA turnov\ner,,Null mutant is viable; overexpression suppresses defects\n in hap2, hap3, and hap3 mutants; isf1 mbr1 double mutant ha\ns synthetic phenotypes\n Cond334:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_30_minutes\n mCSR2:chs5 spa2 rescue; overexpression rescues the lethality of ch\ns5 spa2 at 37 degrees,,Null mutant is viable\n Cond411:diauxic_shift_timecourse_20.5_h\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYIL057C:Unknown ,, Unknown\n Cond815:Na+FK60'\n Cond453:YP_ethanol_vs_reference_pool_car-2\n mHXT5:Member of superfamily of monosaccharide transporters,hexose \ntransporter,Null mutant is viable\n Cond699:gal4-gal\n mYLR345W:Unknown ,, Unknown\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n mPHM7:Hypothetical ORF,,transcription is regulated by PHO system\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n mYGR290W:Unknown ,, Unknown\n mHXT15:High-affinity hexose transporter,hexose transporter,\n Cond421:YPD_5_d_ypd-2\n mHXT16:hexose transporter,hexose permease,\n mYOR391C:Unknown ,, Unknown\n mMBR1:Involved in mitochondrial biogenesis,,Null mutant is viable,\n shows defective growth on glycerol\n mMLS1:carbon-catabolite sensitive malate synthase,carbon-catabolit\ne sensitive malate synthase,Null mutant is viable\n Cond428:YPD_stationary_phase_3_d_ypd-1\n mSPO20:DBF2 Interacting Protein; SNAP 25 homolog,DBF2 interacting p\nrotein , SNAP 25 homolog,Null mutant is viable, other mutant\n fails to form spores\n Stress.tempsteady:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond703:gal10-gal\n
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Computational Genomics Lab, Tel-Aviv uniresity