Module number 1029




Database revision : gnsdb28.10
Date : Tue Feb 25 17:32:36 2003
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mRAD27:DNA repair protein that belongs to the RAD2(pombe)/FEN1 subf\namily,42 kDa 5' to 3' exonuclease required for Okazaki fragm\nent processing,Null mutant is viable, demonstrates temperatu\nre-sensitive growth and sensitivity to UV light and to methy\nlmethane sulfonate\n Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n Cond498:wtħ500nMaF,30minlog10(intensity)\n Cond541:fus3D+50nMaF,30min/wtlog10(intensity)\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes.  Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond221:yer083c\n Cond494:wtħ5nMaF,30minlog10(intensity)\n Cond548:cln3-2\n Cond751: Cond13:ase1(**12)\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns.  J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond533:fus3D+50nMaF/wt+50nMaF,30minlog10(intensity)\n Cond579:cdc15_140\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond883:5\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond505:wtħ50nMaF,120minlog10(intensity)\n mGAS3:Unknown ,, Unknown\n Cond916:(99i5)__HBY4_YPGL+G_NormInt\n Cond562:alpha77\n Cond805:Ca/Ca+FK30'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond568:alpha119\n mYPL267W:Unknown ,, Unknown\n Cond279:ERG11(tetpromoter)\n Cond553:alpha14\n Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n Cond216:yer044c(haploid)\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond482:WT+/-100mM3AT(SetC)(KNY164)\n Cond580:cdc15_150\n Cond804:Ca/Ca+FK15'\n Cond65:fus3(haploid)\n Cond797:Ca15'\n Cond767:Acid_40'\n mBBP1:Involved in mitotic cell cycle and meiosis,,Null mutant is i\nnviable; cells depleted of Bbp1p are defective in nuclear se\ngregation, bud formation, cytokinesis and nuclear spindle fo\nrmation; overexpression gives ascus that contains asci inste\nad of spores\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond54:erg3(haploid)\n Cond581:cdc15_160\n Cond692:gal6+gal\n Cond558:alpha49\n Cond68:gas1\n Cond734: Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Cond945:W303_YPD\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond746: Cond819:crz1/Na45'_\n Cond582:cdc15_170\n Cond314:Heat_Shock_060_minutes__hs-2\n Y-Stre.Alkali:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond706:gal2gal80-gal\n Cond571:cdc15_50\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond965:ndt80_delete_mid_g/r_ratio_\n Cond737: Cond555:alpha28\n mYNR009W:Unknown ,, Unknown\n Cond493:wtħ1.5nMaF,30minlog10(intensity)\n Cond570:cdc15_30\n Cond960:t5_g/r_ratio\n mRNR1:ribonucleotide reductase,ribonucleotide reductase, large (R1\n) subunit,Null mutant is inviable\n Cond503:wtħ50nMaF,60minlog10(intensity)\n Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n Cond750: Cond510:fus3Dħ50nMaF,30minlog10(intensity)\n Cond567:alpha112\n Cond40:dig1,dig2\n Cond547:cln3-1\n mMCD1:Mitotic Chromosome Determinant; similar to S. pombe RAD21; m\nay function in chromosome morphogenesis from S phase through\n mitosis,,Null mutant is inviable; temperature sensitive mut\nants are defective in mitotic sister chromatid cohesion and \nmitotic chromosome condensation; multicopy suppressor of smc\n1-2 mutation\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond500:wtħ50nMaF,15minlog10(intensity)\n Cond504:wtħ50nMaF,90minlog10(intensity)\n Cond770:Acid_100'\n Cond519:rst1Drst2Dħ50nMaF,30minlog10(intensity)\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt.  Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond384:Hypo-osmotic_shock_-_5_min\n Cond53:erg2\n Y-Stre.Acid:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond733: Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n Cond496:wtħ50nMaF,30minlog10(intensity)\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond893:SMMS\n Cond768:Acid_60'\n Cond379:1M_sorbitol_-_30_min\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Cond287:2-deoxy-D-glucose\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast.  Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond502:wtħ50nMaF,45minlog10(intensity)\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Cond563:alpha84\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n  Science. 1998 Oct 23;282(5389):699-705.\n mCDC21:cell division cycle blocked at 36 degree C,thymidylate synth\nase,defective in continued replication during S phase of the\n cell cycle; temperature-sensitive thymidylate auxotroph\n Stress.Menadione:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond175:swi4\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond250:ymr031w-a\n Cond501:wt+/-50nMaF,30minlog10(intensity)\n Cond98:mbp1\n Cond554:alpha21\n Cond738:90\n Cond398:Nitrogen_Depletion_4_h\n Calcin.crz1Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond743: Cond776:Alkali_100'\n Cond294:Itraconazole\n mDUN1:DNA damage response,protein kinase,Null mutant is viable, de\nfective in DNA damage repair and in DNA damage-resposive ind\nuction of RNR genes, and sensitive to DNA damaging agents\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mSPT21:involved in trascriptional regulation of Ty1 LTRs,non-specif\nic DNA binding protein,Null mutant is viable, spt21 mutation\ns suppress Ty insertion mutations\n Cond747: Cond538:fus3D/wtlog10(intensity)\n Cond348:1mM_Menadione_(40_min)_redo\n mUFE1:t-SNARE that resides on the endoplasmic reticulum and mediat\nes retrograde traffic from the Golgi complex,t-SNARE (ER),Nu\nll mutant is inviable\n Cond497:wtħ158nMaF,30minlog10(intensity)\n mHSL1:Negative regulator of swe1 kinase (which regulates cdc28),pr\notein kinase  (putative) , similar to S. pombe cdr1/nim1,Nul\nl mutant is viable; synthetically lethal with histone H3 mut\nations; G2 delay\n Cond560:alpha63\n Cond299:Tunicamycin\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast.  Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond736: Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond559:alpha56\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n Cond551:alpha0\n Cond549:clb2-2\n Cond939:4h\n mYOX1:Homeodomain protein that binds leu-tRNA gene,homeobox-domain\n containing protein,Null mutant is viable\n

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Computational Genomics Lab, Tel-Aviv uniresity