Module number 1012




Database revision : gnsdb28.10
Date : Tue Feb 25 17:30:55 2003
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mYKR027W:Unknown ,, Unknown\n mHAP5:Regulates respiratory functions; subunit of a heterotrimeric\n complex required for CCAAT binding,CCAAT-binding transcript\nion factor component (along with Hap2p and Hap3p),Null mutan\nt is viable\n mYDR094W:Unknown ,, Unknown\n mYGL114W:Unknown ,, Unknown\n mCEG1:mRNA guanylyltransferase (mRNA capping enzyme), alpha subuni\nt,mRNA capping enzyme alpha subunit , mRNA guanylyltransfera\nse,Null mutant is inviable\n mYLR404W:Unknown ,, Unknown\n mVAC14:Unknown ,, Unknown\n Cond708:t0+SSD1\n mCHS6:Involved in chitin biosynthesis and/or its regulation,,Reduc\ned levels of chitin, temperature-sensitive growth on rich me\ndium in certain genetic backgrounds\n Cond725:t4-SSD1,M31\n Cond711:t2+Vec\n Cond780:Peroxide_10'\n mCBP3:Protein required for assembly of ubiquinol cytochrome-c redu\nctase complex (cytochrome bc1 complex),,reduced levels of a \nsubset of subunit polypeptides of the coenzyme QH2-cytochrom\ne c reductase complex\n mQNS1:Hypothetical ORF,,\n mYBL065W:Unknown ,, Unknown\n mYEL015W:Unknown ,, Unknown\n Cond712:t4+SSD1\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond661:DES460_(wt)_-_mock_irradiation_-_90_min\n mMTF1:Mitochondrial RNA polymerase specificity factor,mitochondria\nl RNA polymerase specificity factor,Null mutant is viable, d\nefective in respiration, and lacks mtDNA.\n mROT1:Reversal of tor2 lethality,membrane protein (putative),Null \nmutant is inviable; rot1 mutations can suppress tor2 mutatio\nns; synthetically lethal with rot2\n mSFP1:Inhibits nuclear protein localization when present in multip\nle copies,split zinc finger protein,Null mutant is viable, g\nrows slowly, cells have multiple nucleated buds\n mYDR128W:Unknown ,, Unknown\n mPSR2:Plasma membrane Sodium Response 2,,Mutant is sensitive to so\ndium ions.\n Cond723:t2-SSD1,M31\n mSUL2:Sulfate uptake,high affinity sulfate permease,\n Cond724:t4+SSD1,H44\n Cond714:t0+SSD1wt\n Cond715:t0-SSD1\n Cond713:t4+Vec\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mKIC1:Kinase that interacts with Cdc31p; N-rich kinase 1,,\n mYLR072W:Unknown ,, Unknown\n mDDI1:DNA Damage Inducible; binds to T- and V- snare complexes,,Nu\nll mutant is viable\n Cond718:t4+SSD1wt\n Cond721:t0-SSD1,M31\n mYND1:Yeast Nucleoside Diphosphatase,apyrase (NDPase/NTPase),Null \nmutant is viable but vanadate-resistant and hygromycin-sensi\ntive. The double mutant ynd1 gda1 exhibits slow growth and s\nubstantial defects in protein glycosylation and cell morphol\nogy.\n Cond672:DES459_(mec1)_-_mock_irradiation_-_60_min\n Y-Stre.Peroxide:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n mYLR454W:Unknown ,, Unknown\n Cond709:t0+Vec\n mRRN10:subunit of UAF (upstream activation factor); involved in pro\nmoting high level transcription of rDNA,upstream activation \nfactor subunit,Mutant shows reduction in the transcription o\nf rDNA\n mPTP1:phosphotyrosine-specific protein phosphatase,phosphotyrosine\n-specific protein phosphatase,viable\n Cond671:DES459_(mec1)_-_mock_irradiation_-_30_min\n Cond710:t2+SSD1\n mGIS1:putative zinc finger protein; repressor of PHR1 transcriptio\nn,zinc finger protein (putative),Null mutant is viable and s\nhows enhanced basal level expression of PHR1\n mRGA1:putative GTPase-activating protein for the polarity-establis\nhment protein Cdc42p or Rho1p; activates the pheromone-respo\nnse pathway,rho GTPase activating protein (GAP),Null mutant \nis viable but shows increased signaling in the pheromone pat\nhway; haploid null mutants bud predominantly in a bipolar, r\nather than the normal axial, manner\n mVPS34:phosphatidylinositol 3-kinase,phosphatidylinositol 3-kinase,\ntemperature sensitive, defective vacuolar protein sorting\n mHRD3:HMG-CoA Reductase Degradation,,Null mutant is viable, slows \ndegradation of Hmg2p\n Cond660:DES460_(wt)_-_mock_irradiation_-_60_min\n mBPT1:bile pigment transporter,ABC transporter , highly homologous\n to human MRP1 and to C. elegans mrp-1,Null mutant is viable\n but lacks approximately 40% of the trasport activity of unc\nonjugated bilirubin into the vacuolar system of yeast\n
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Computational Genomics Lab, Tel-Aviv uniresity