Module number 2387




Database revision : gnsdb28.10
Date : Tue Feb 25 17:19:39 2003
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PEX.Pex:Transcriptome profiling to identify genes involved in peroxi\nsome assembly and function.  J Cell Biol. 2002 Jul 22;158(2)\n:259-71.\n Cond698:gal3-gal\n mSDH1:flavoprotein subunit of succinate dehydrogenase,succinate de\nhydrogenase flavoprotein subunit,no growth on glycerol (unab\nle to respire)\n Cond548:cln3-2\n mSIT1:Siderophore Iron Transport,ferrioxamine B permease,Viable. C\nells deleted from the gene are unable to take up ferrioxamin\ne B\n Cond697:gal2-gal\n mDLD1:mitochondrial enzyme D-lactate ferricytochrome c oxidoreduct\nase,D-lactate ferricytochrome c oxidoreductase,Null mutant i\ns viable and cannot grow on media containing lactate as the \nsole carbon source\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n mPOX1:fatty-acyl coenzyme A oxidase,fatty-acyl coenzyme A oxidase,\nNull mutant is viable, exhibits diminished ability to use ol\neic acid as a carbon source\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond454:YP_fructose_vs_reference_pool_car-2\n mSNF3:glucose sensor,glucose sensor,Null mutant is viable, defecti\nve in high affinity glucose transport, unable to grow on low\n glucose media, unable to grow on raffinose; snf3 delta hxt1\n delta hxt2 delta hxt3 delta hxt4 delta cells are unable to \ngrow on media containing high concentrations of glucose (5%)\n but can grow on low-glucose (0.5%) media; expression of SNF\n3 abolishes growth of hxt1 delta hxt2 delta hxt3 delta hxt4 \ndelta cells on low-glucose medium\n Cond300:Heat_Shock_05_minutes_hs-1\n Cond702:gal7-gal\n Cond696:gal1-gal\n Cond310:Heat_Shock_000_minutes_hs-2\n Cond705:gal1gal10+gal\n Cond701:gal6-gal\n mMEK1:Disp. for chr. pairing & chr. condensation seen by in situ h\nybrid. Required for full double strand breaks, normal length\n synaptonemal complexes, meiotic recomb. & spore viability. \nmek1 is rescued by spo13 & in early recomb. function,meiosis\n-specific serine/threonine protein kinase,Null mutant is via\nble, however diploids homozygous for a mek1 null mutation pr\noduce only low percentages of viable spores, reduced spore v\niability is rescued by spo13 mutations\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond857:pm38-gtoe\n mHSP26:heat shock protein 26,heat shock protein 26,Null mutant is v\niable; hsp26 hsp42 double deletion mutants are viable\n Cond689:gal3+gal\n Cond449:glucose_vs._reference_pool_car-1\n Cond271:yor051c(**14)\n Cond452:sucrose_vs._reference_pool_car-1\n Cond693:gal7+gal\n Cond694:gal10+gal\n mYNL077W:Unknown ,, Unknown\n Cond700:gal5-gal\n Cond844:expt7\n Cond688:gal2+gal\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond456:YP_glucose_vs_reference_pool_car-2\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n mYLR312C:Unknown ,, Unknown\n mALD4:Glucose repressed. Utilizes NADP+ or NAD+ as a coenzyme equa\nlly well. (sold by SIGMA under the catalogue number A5550, a\nccording to A. Blomberg).,aldehyde dehydrogenase,\n mALD6:Utilizes NADP+ as the preferred coenzyme. Activated by Mg2+.\n,aldehyde dehydrogenase,Null mutant is viable, grows at appr\noximately one-third the rate of wild-type, unable to grow on\n ethanol as a carbon source\n mYNL194C:Unknown ,, Unknown\n mHSP30:Protein induced by heat shock, ethanol treatment, and entry \ninto stationary phase; located in plasma membrane,,\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond314:Heat_Shock_060_minutes__hs-2\n Cond687:gal1+gal\n Cond686:wt+gal\n Cond685:wt-gal\n mYLR327C:Unknown ,, Unknown\n mRAD50:coiled-coil protein, contains a purine-binding domain, two h\neptad repeats and a hydrophobic tail,Mre11-Rad50-Xrs2 protei\nn complex member involved in joining double-stranded breaks \nand DNA recombination,Null mutant is viable but defective fo\nr X-ray damage repair, sporulation, chromosome pairing, form\nation and processing of DS breaks, gene conversion and recip\nrocal recombination in non-rDNA, tripartite synaptonemal com\nplexes and heteroduplex DNA. Exhibits blocked meiotic recomb\nination and formation of synaptonemal complex at early stage\ns. rad50-1 or null is rescued by spo13 and rescues rad52 spo\n13.\n mYLR149C:Unknown ,, Unknown\n Cond707:gal4gal80-gal\n Cond411:diauxic_shift_timecourse_20.5_h\n mHXT1:High-affinity hexose (glucose) transporter,high affinity hex\nose (glucose) transporter,Null mutant is viable\n mHXT2:hexose transporter,high affinity hexose transporter-2,Null m\nutant is viable\n mHXT3:Low-affinity glucose transporter,low affinity glucose transp\norter,Null mutant is viable but grows slowly on galactose; s\nome mutant alleles confer sodium hypersensitivity.\n mHXT4:hexose transporter,high affinity glucose transporter,Null mu\ntant is viable\n Cond690:gal4+gal\n Cond699:gal4-gal\n mHXT6:Repression of HXT6 expression by glucose requires SNF3,hexos\ne transporter,Null mutant is viable; snf3 hxt1 hxt2 hxt3 hxt\n4 hxt6 hxt7 mutant cannot grow on media containing glucose a\ns sole carbon source\n mPHM7:Hypothetical ORF,,transcription is regulated by PHO system\n Cond160:sir4\n mESBP6:Protein with similarity to mammalian monocarboxylate transpo\nrters MCT1 and MCT2,monocarboxylate permease (putative),\n mYNL018C:Unknown ,, Unknown\n Cond703:gal10-gal\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n

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Computational Genomics Lab, Tel-Aviv uniresity