Module number 1003




Database revision : gnsdb28.10
Date : Tue Feb 25 17:29:19 2003
How to read this figure?


Cond664:mec1_plus_gamma_20_min\n mURA10:Fifth step in pyrimidine bio5,orotate phosphoribosyltransfer\nase 2,Null mutant is viable\n mHIS3:imidazoleglycerol-phosphate dehydratase,imidazoleglycerol-ph\nosphate dehydratase,Null mutant is viable and requires histi\ndine\n Cond158:sir2\n Cond277:AUR1(tetpromoter)\n Cond476:GCN4C/GCN4(R4760/R6257)\n mHIS7:glutamine amidotransferase:cyclase, also called imidazole gl\nycerol phosphate synthase,glutamine amidotransferase:cyclase\n , imidazole glycerol phosphate synthase (synonym),Null muta\nnt is viable and requires histidine\n Cond221:yer083c\n mARG2:First step in ornithine biosynthesis pathway,acetylglutamate\n synthase,\n mMCH1:Unknown ,, Unknown\n mMKK2:Member of MAP kinase pathway involving PKC1, BCK1, and SLT2.\n Shows functional redundancy with MKK1,protein kinase,Null m\nutant is viable and shows no obvious phenotypes; mkk1 mkk2 d\nouble mutant is caffeine-sensitive and shows a temperature-s\nensitive cell lysis defect remediated by osmotic stabilizers\n mSSU1:sensitive to sulfite,major facilitator superfamily,Null muta\nnt is viable; sulfite sensitive\n Cond29:clb2\n Cond13:ase1(**12)\n mDRE3:Unknown ,, Unknown\n mYNL116W:Unknown ,, Unknown\n mYOR192C:Unknown ,, Unknown\n Cond730:hda1\n mARO1:pentafunctional arom polypeptide (contains: 3-dehydroquinate\n synthase, 3-dehydroquinate dehydratase (3-dehydroquinase), \nshikimate 5-dehydrogenase, shikimate kinase, and epsp syntha\nse),3-dehydroquinate dehydratase (3-dehydroquinase) , 3-dehy\ndroquinate synthase , epsp synthase , pentafunctional arom p\nolypeptide , shikimate 5-dehydrogenase , shikimate kinase,ar\nomatic amino acid requiring; lack of premeiotic DNA synthesi\ns; blocked sporulation in homozygous mutant\n mECM4:ExtraCellular Mutant,,A Tn3 insertion into this gene causes \nhypersensitivity to the cell surface polymer perturbing agen\nt calcofluor white.\n mYPR059C:Unknown ,, Unknown\n mERG4:Sterol C-24 reductase,sterol C-24 reductase,Null mutant is v\niable\n mARO9:aromatic amino acid aminotransferase II,aromatic amino acid \naminotransferase II,Null mutant is viable\n mYBR030W:Unknown ,, Unknown\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n mOAC1:oxaloacetate carrier,oxaloacetate transport protein,\n Cond53:erg2\n mYMR166C:Unknown ,, Unknown\n mYHR122W:Unknown ,, Unknown\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mGPB1:G-Protein Effector,G protein effector,\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond184:ubr1\n Cond123:rad57\n Cond6:anp1\n Cond298:Terbinafine\n mYHR162W:Unknown ,, Unknown\n mYOL085C:Unknown ,, Unknown\n mPAI3:Cytoplasmic inhibitor of proteinase Pep4p,inhibitor of prote\ninase Pep4p,Null mutant is viable but shows increased rate o\nf protein degradation\n Cond279:ERG11(tetpromoter)\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYHR199C:Unknown ,, Unknown\n mYJR026W:Unknown ,, Unknown\n mYOR044W:Unknown ,, Unknown\n Cond201:yel008w\n Cond229:yhr011w(**14)\n Cond216:yer044c(haploid)\n mPEX21:Peroxin; Pex18p and Pex21p are partially functionally redund\nant.,peroxin,Null mutant is viable.\n Cond479:WT+/-100mM3AT(SetD)(R491)\n mYLR104W:Unknown ,, Unknown\n mICY2:Interacting with the cytoskeleton,,\n Cond482:WT+/-100mM3AT(SetC)(KNY164)\n Cond226:yhl029c\n Cond287:2-deoxy-D-glucose\n mMET16:3'phosphoadenylylsulfate reductase,3'phosphoadenylylsulfate \nreductase,Null mutant is viable, and is a methionine auxotro\nph\n Cond478:WT+/-10mM3AT(R491)\n mTRP4:anthranilate phosphoribosyl transferase,anthranilate phospho\nribosyl transferase,tryptophan requiring\n Cond43:dot4\n mNDE2:Unknown ,, Unknown\n mLSC2:beta subunit of succinyl-CoA ligase (synthetase; ATP-forming\n), a mitochondrial enzyme of the TCA cycle,,Null mutant is v\niable but grows slowly on minimal glycerol or pyruvate; muta\nnt suppresses idh2 null mutants for growth on glycerol\n Cond54:erg3(haploid)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond481:WT+/-100mM3AT(SetB)(491)\n mYKL033W-A:Unknown ,, Unknown\n mYDL183C:Unknown ,, Unknown\n mILV1:threonine deaminase,threonine deaminase,Isoleucine-plus-vali\nne requiring\n Cond171:ste24(haploid)\n mASN1:Asn1p and Asn2p are isozymes,asparagine synthetase,Null muta\nnt is viable; L-asparagine auxotrophy occurs upon mutation o\nf both ASN1 and ASN2\n Cond175:swi4\n Cond69:gcn4\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond250:ymr031w-a\n mYNL129W:Unknown ,, Unknown\n mYNL311C:Unknown ,, Unknown\n mARG80:Regulator of arginine-responsive genes with ARG81 and ARG82,\ntranscription factor,Arginine requiring\n Cond27:ckb2\n mYBR293W:Unknown ,, Unknown\n mYDR262W:Unknown ,, Unknown\n mBIO4:dethiobiotin synthetase,dethiobiotin synthetase,\n mYJR154W:Unknown ,, Unknown\n mMEP1:ammonia permease,ammonia permease,\n mPHO89:Probable Na+/Pi symporter,Na+/Pi symporter (putative),Null m\nutant is viable\n mMET22:Putative phosphatase gene involved in salt tolerance and met\nhionine biogenesis; halotolerance,3'(2')5'-bisphosphate nucl\neotidase,Methionine requiring; lacks 3'-phosphoadenylylsulfa\nte (PAPS) reductase activity; unable to grow on sulfate as s\nole sulfur source\n Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n Cond294:Itraconazole\n mHBT1:Unknown ,, Unknown\n mIDP1:Mitochondrial form of NADP-specific isocitrate dehydrogenase\n,NADP-dependent isocitrate dehydrogenase,Null mutant is viab\nle\n mYIR016W:Unknown ,, Unknown\n Cond299:Tunicamycin\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n mYMR244W:Unknown ,, Unknown\n mYCR099C:Unknown ,, Unknown\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mPIN3:[PSI+] induction,,Other phenotypes: overexpression of PIN3 a\nllows for the induction of the [PSI+] prion in strains cured\n of [PIN+].\n mORT1:Mitochondrial integral membrane protein, ornithine transport\ner,,Null mutant is viable, arginine bradytroph\n mCPA2:carbamyl phosphate synthetase,carbamyl phosphate synthetase,\nNull mutant is viable\n mESBP6:Protein with similarity to mammalian monocarboxylate transpo\nrters MCT1 and MCT2,monocarboxylate permease (putative),\n mSPO21:sporulation defective,,meiosis proficient, fails to form spo\nres\n mHIS1:involved in the first step of histidine biosynthesis,ATP pho\nsphoribosyltransferase,Null mutant is viable and requires hi\nstidine\n mYNL116W mYNL311C
this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity