What is syncmer mapping?
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Syncmer mapping is a method of mapping long-reads using syncmers as seeds instead of minimizers.
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When introducing syncmer schemes into the popular minimap2 and Winnowmap2 mappers, at high compression rates, unmapped reads dropped by 20-60% while using less memory.
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Syncmer mapping was developed by Abhinav Dutta, David Pellow, and Ron Shamir.
Where is the syncmer mapping paper and software?
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Syncmer mappers are available on Github.
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A manuscript describing general parameterized syncmer schemes and the syncmer-minimap and syncmer-winnowmap mappers is available on bioRxiv.
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It can be cited as follows:
Dutta, A, Pellow D, Shamir R. Using syncmers improves long-read mapping. bioRxiv. 2022.
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