Module mitotic_cell_cycle




Database revision : gnsdb28.10
Date : Fri Feb 28 01:36:32 2003
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mRAD27:DNA repair protein that belongs to the RAD2(pombe)/FEN1 subf\namily,42 kDa 5' to 3' exonuclease required for Okazaki fragm\nent processing,Null mutant is viable, demonstrates temperatu\nre-sensitive growth and sensitivity to UV light and to methy\nlmethane sulfonate\n Cond498:wtħ500nMaF,30minlog10(intensity)\n Cond494:wtħ5nMaF,30minlog10(intensity)\n mHLR1:LRE1 homolog,,Null mutant is viable.\n Cond548:cln3-2\n Cond751: Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond533:fus3D+50nMaF/wt+50nMaF,30minlog10(intensity)\n mHHO1:Histone H1,histone H1,Null mutant is viable; other phenotype\n: Increased basal expression of a CYC1-lacz reporter gene; n\nuclear localization of a Hho1-GFP fusion protein\n mCLB5:role in DNA replication during S phase; additional functiona\nl role in formation of mitotic spindles along with Clb3 and \nClb4,B-type cyclin,Null mutant is viable, but has an extende\nd S phase\n mYBR070C:Unknown ,, Unknown\n Cond579:cdc15_140\n mCLB6:role in DNA replication during S phase,B-type cyclin,Null mu\ntant is viable\n mMNN1:Alpha-1,3-mannosyltransferase,alpha-1,3-mannosyltransferase,\nNull mutant is viable\n mRFA1:Required for DNA-damage repair, full levels of gene conversi\non and sporulation,heterotrimeric RPA (RF-A) single-stranded\n DNA binding protein 69 kDa subunit; binds URS1 and CAR1,Nul\nl mutant is inviable; cells lacking RFA1 accumulate as multi\nply budded cells with a single nucleus suggesting a defect i\nn DNA replication; rfa1 repair defects are suppressed by hig\nh copy RAD52\n mRFA2:Involved in nucleotide excision repair,29% identical to the \nhuman p34 subunit of RF-A , replication factor RF-A subunit \n2,Null mutant is inviable; arrests as budded and multiply bu\ndded cells; rfa2 (ts) cells have a mutator and a hyper-recom\nbination phenotype and are more sensitive to hydroxyurea and\n methyl-methane-sulfonate than wild-type cells\n mRFA3:subunit 3 of replication factor-A,replication factor-A subun\nit 3,Null mutant is inviable and arrests as budded and multi\nply budded cells\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n mYLR049C:Unknown ,, Unknown\n mYKR012C:Unknown ,, Unknown\n mPOL12:Required for DNA synthesis and correct progression through S\n phase; plays an essential role at early stage of chromosoma\nl DNA replication, before the hydroxyurea-sensitive step,DNA\n polymerase alpha-primase complex B subunit,Null mutant is i\nnviable\n mCDC45:Cdc45p assembles into a complex with Cdc46p/Mcm5p,chromosoma\nl DNA replication initiation protein,required for minichromo\nsome maintenance and chromosomal DNA replication\n mYDL163W:Unknown ,, Unknown\n mGAS1:Glycophospholipid-anchored surface protein,cell surface glyc\noprotein 115-120 kDa,Null mutant is slow growing and exhibit\ns cell wall defects.\n mCDC9:essential for mitosis and meiosis, dispensable for intrageni\nc recombination, but required for haploidization and spores,\nDNA ligase,cell division cycle blocked at 36 degrees, increa\nsed sensitivity to ultraviolet radiation and bleomycin; temp\nerature sensitive\n mCTF18:Chromosome transmission,,Null mutant is viable, exhibits inc\nreased level of spontaneous mitotic recombination, slow grow\nth, and cold sensitivity\n Cond562:alpha77\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Cond480:WT+/-100mM3AT(SetA)(R491)\n mMRC1:Mediator of the Replication Checkpoint; required for full ac\ntivation of Rad53p in response to replication stress.,,Null:\n sensitive to hydroxyurea; replication checkpoint defective;\n slower DNA replication than wild type; partial loss of sile\nncing at telomeres and HM loci; synthetic lethal with rad9 n\null, rad53-21, and mec1-21.\n mCRH1:congo red hypersensitive,cell wall protein,Null mutant is vi\nable and hypersensitive to Congo Red and Calcofluor White\n mYKR077W:Unknown ,, Unknown\n Cond568:alpha119\n mPDS1:May be an anaphase inhibitor that plays a critical role in c\nontrol of anaphase by both the anaphase promoting complex (A\nPC) and DNA-damage checkpoints,42 kDa nuclear protein,Null m\nutant is viable but is temperature-sensitive; shows higher r\nates of chromosome loss at permissive temperature; at restri\nctive temperature, fails to elongate spindles and shows unco\nupling of cell cycle progression from completion of anaphase\n mYMR144W:Unknown ,, Unknown\n mPDS5:Precocious Dissociation of Sister chromatids,,\n mYPL267W:Unknown ,, Unknown\n Cond279:ERG11(tetpromoter)\n Cond553:alpha14\n Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n mYHP1:Hypothetical ORF,,\n mRDH54:genetic interaction with DMC1,helicase (putative) , similar \nto RAD54,Required for meiosis. Early meiotic induction of ge\nne conversion is wild-type in a tid1 deletion but mature cro\nssover products form slowly and cells block with single nucl\nei even though the spindle pole bodies duplicate and separat\ne twice, as if progressing to entry into the second meiotic \ndivision.\n mMSH2:Functions with Pms1p and Pms2/Mlh1p in a complex that intera\ncts with Pms3p/Msh6p to repair single-base and insertion-del\netion mispairs, or Msh3p to repair insertion-deletion mispai\nrs.,mutS homolog,Null mutant is viable. Haploid mutants disp\nlay an 85-fold increased rate of spontaneous mutation to can\navanine resistance. Mutants are defective for gene conversio\nn polarity gradients and high spore viability.\n mMSH6:Required for mismatch repair in mitosis & meiosis, low level\ns of postmeiotic segregation & high spore viability; forms c\nomplex with Msh2p to repair both single-base & insertion-del\netion mispairs; redundant with Msh3p in repair of in-dels,hu\nman GTBP protein homolog,Null mutant is viable, msh3 msh6 do\nuble deletion mutants exhibit microsatellite instability and\n mutability similar to that in a msh2 mutant\n Cond580:cdc15_150\n mHIF1:Hat1 Interacting Factor 1,,Null mutant is viable and does no\nt show any obvious phenotypes\n mPRI2:p58 polypeptide of DNA primase,DNA primase p58 polypeptide,l\nethal\n mYHR149C:Unknown ,, Unknown\n mBBP1:Involved in mitotic cell cycle and meiosis,,Null mutant is i\nnviable; cells depleted of Bbp1p are defective in nuclear se\ngregation, bud formation, cytokinesis and nuclear spindle fo\nrmation; overexpression gives ascus that contains asci inste\nad of spores\n mYBR071W:Unknown ,, Unknown\n mSPC98:Involved in microtubule organization by the SBP,spindle pole\n body component,Null mutant is inviable; overexpression is t\noxic resulting in accumulation of cells with large buds, 2N \nDNA content, defect in microtubule structure. ts-phenotype: \narrest in G2 of cell cycle with large bud, duplicated spindl\ne pole bodies, short spindle and elongated cytoplasmic micro\ntubules\n Cond54:erg3(haploid)\n Cond581:cdc15_160\n Cond558:alpha49\n mSEN34:tRNA splicing endonuclease 34kDa subunit; homologous to the \n42-kDa subunit, SEN2; contains active site for 3' splice sit\ne cleavage,tetrameric tRNA splicing endonuclease 34 kDa subu\nnit,Null mutant is inviable and shows H242A impaired 3'splic\ne site cleavage\n Cond734: mRTT107:Establishes Silent Chromatin,,\n mRTT109:Regulation of mitochondrial network; Killed in Mutagen, sens\nitive to diepoxybutane and/or mitomycin C,,Mutant exhibits a\nbnormal mitochondrial morphology and slight growth defect in\n dextrose; insertion/truncation at amino acid 332 yields sen\nsitivity to diepoxybutane and to mitomycin C\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond746: Cond582:cdc15_170\n mRAD51:Involved in processing ds breaks, synaptonemal complex forma\ntion, meiotic gene conversion and reciprocal recombination.,\nRad51p colocalizes to ~ 65 spots with Dmc1p prior to synapsi\ns (independently of ZIP1 and DMC1), and interacts with Rad52\np and Rad55p; human Rad51p homolog interacts with Brca2 prot\nein which has been implicated in causing breast cancer , Rec\nA homolog,Null mutant is viable; accumulates meiosis-specifi\nc double strand breaks at a recombination hotspot and reduce\ns the formation of physical recombinants and processed doubl\ne strand breaks with long heterogeneous tails; rad51 mutants\n are also defective for X-ray damage repair and gene convers\nions; rad51 rad27 mutants are inviable.\n mPOL30:Accessory factor for DNA polymerase delta, mRNA increases in\n G1, peaks in S in mitosis, & increases prior to DNA synthes\nis in meiosis; required for DNA replication & repair, requir\ned for viability in cdc44, rad50, rad52 or rad57 backgrounds\n,,Null mutant is inviable\n Cond571:cdc15_50\n mRAD53:Required for DNA damage-induced checkpoint arest in G1, S/M,\n and G2/M in mitosis, dispensable for sporulation but requir\ned for wild-type spore viability; Mec1p and Tel1p regulate r\nad53p phosphorylation,protein kinase,Null mutant is inviable\n, radiation sensitive\n mDPB2:DNA polymerase epsilon, subunit B,DNA polymerase epsilon sub\nunit B,Null mutant is inviable; conditional mutant shows def\nects in DNA replication\n mRSR1:Gtp-binding protein of the ras superfamily involved in bud s\nite selection,,random budding pattern\n mPRY2:Pathogen Related in Sc, contains homology to the plant PR-1 \nclass of pathogen related proteins. The protein sequence is \nover 60% identical with the Pry2p & Pry3p over 145 resid. PR\nY1 is >35% identical (50% similar) to tobacco PR-1c protein.\n,,\n Cond965:ndt80_delete_mid_g/r_ratio_\n Cond737: Cond555:alpha28\n Cond493:wtħ1.5nMaF,30minlog10(intensity)\n mYNR009W:Unknown ,, Unknown\n mMSB2:putative integral membrane protein,integral membrane protein\n (putative),multicopy suppressor of cdc24 ts mutation\n mSVS1:involved in vanadate resistance,,Null mutant is viable, show\ns increased sensitivity to vanadate, but not other metallic \nions or drugs\n Cond570:cdc15_30\n mRNR1:ribonucleotide reductase,ribonucleotide reductase, large (R1\n) subunit,Null mutant is inviable\n Cond503:wtħ50nMaF,60minlog10(intensity)\n Cond511:GAL-STE4,3hrs.gallog10(intensity)\n mRNR3:Ribonucleotide reductase (ribonucleoside-diphosphate reducta\nse) large subunit,ribonucleotide reductase, large (R1) subun\nit,Null mutant is viable\n mESC8:Unknown ,, Unknown\n Cond750: Cond510:fus3Dħ50nMaF,30minlog10(intensity)\n Cond567:alpha112\n Cond547:cln3-1\n mTOS2:Hypothetical ORF,,\n mMCD1:Mitotic Chromosome Determinant; similar to S. pombe RAD21; m\nay function in chromosome morphogenesis from S phase through\n mitosis,,Null mutant is inviable; temperature sensitive mut\nants are defective in mitotic sister chromatid cohesion and \nmitotic chromosome condensation; multicopy suppressor of smc\n1-2 mutation\n mAXL2:involved in polarity establishment/cellular polarization dur\ning budding,,AXL2 can serve as a multicopy suppressor of rho\n3 and is required for the haploid axial budding pattern of S\n. cerevisiae.\n mPOL1:Required for mitotic DNA synthesis, premeiotic DNA synthesis\n, recombination, and full sporulation,DNA polymerase I alpha\n subunit p180,Null mutant is inviable. pol1(ts) mutants show\n blocked cell division at 36 degrees C\n mTOS4:Hypothetical ORF,,\n mPOL2:DNA polymerase II,DNA polymerase II,\n mTOS6:Hypothetical ORF,,\n Cond500:wtħ50nMaF,15minlog10(intensity)\n mOCH1:membrane-bound alpha-1,6-mannosyltransferase,alpha-1,6-manno\nsyltransferase,Null mutant is viable, temperature sensitive,\n lacks mannose outer chains\n mGIN4:Growth inhibitory gene,serine/threonine kinase (putative),Nu\nll mutant is viable, exhibits a mild elongated bud phenotype\n and some cell clumping\n mYIL141W:Unknown ,, Unknown\n mTUB4:spindle pole body component that organizes both cytoplasmic \nand nuclear microtubule arrays,gamma tubulin-like protein , \ninteracts with Spc98p and Spc97p, the Tub4p-Spc98p-Spc97p co\nmplex may be part of the microtubule attachment site at the \nspindle pole body,Null mutant is inviable. Tub4p-depleted ce\nlls arrest during nuclear division; most arrested cells cont\nain a large bud, replicated DNA, and a single nucleus. Immun\nofluorescence and nuclear staining experiments indicate that\n cells depleted of Tub4p contain defects in the organization\n of both cytoplasmic and nuclear microtubule arrays; such ce\nlls exhibit nuclear migration failure, defects in spindle fo\nrmation, and/or aberrantly long cytoplasmic microtubule arra\nys.\n Cond504:wtħ50nMaF,90minlog10(intensity)\n mHPR5:Required for proper timing of committment to meiotic recombi\nnation and the transition from Meiosis I to Meiosis II,DNA h\nelicase,Null mutant is viable, radiation (ultraviolet or ion\nizing sensitive), loss of function results in RAD52-dependen\nt hyperrecombination suggesting recombination suppression oc\ncurs by antagonizing the Rad52 recombinational repair pathwa\ny; wild-type suppresses mitotic recombination; some mutant a\nlleles have lower spore viability which is not rescued by sp\no13, suggesting they affect a late recombination function; h\npr5 mutations are rad6 suppressors\n Cond519:rst1Drst2Dħ50nMaF,30minlog10(intensity)\n Cond586:cdc15_210\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt.  Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond733: Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n Cond496:wtħ50nMaF,30minlog10(intensity)\n mCLN1:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest\n mCLN2:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest; dominant mutation advances the G(sub)1- to\n S- phase transition and impairs ability of cells to arrest \nin G(sub)1 phase in response to external signals\n mSPH1:SPa2-Homolog; protein involved in shmoo formation and requir\ned for bipolar bud site selection (GB:AF008236).,Spa2p homol\nog,Null mutant is viable but results in defects in shmoo for\nmation.\n mPMS1:Required for mismatch repair in mitosis and meiosis, low lev\nels of postmeiotic segregation, and high spore viability, di\nspensable for homeologous recombination,mutL homolog , simil\nar to Mlh1p, associates with Mlh1p, possibly forming a heter\nodimer, Pms1p and Msh1p act in concert to bind to a Msh2p-he\nteroduplex complex containing a G-T mismatch,Null mutant is \nviable; postmeiotic segregation increased\n mYCL022C:Unknown ,, Unknown\n mCTF4:May function in DNA synthesis,DNA polymerase alpha binding p\nrotein,Null mutant is viable but shows increase in the rate \nof mitotic chromosome loss, increased mitotic recombination,\n shift toward cells with G2 DNA content, and large budded ce\nlls with the nucleus in the bud neck; shows synthetic intera\nctions with rad52, pol1, rad9, and esr1\n mYGR151C:Unknown ,, Unknown\n mCSI2:chitin synthase involved,chitin synthase 3 complex structura\nl component (putative),Null mutant is viable but shows deloc\nalized chitin deposition\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond550:clb2-1\n mHHT1:Histone H3 (HHT1 and HHT2 code for identical proteins),histo\nne H3 (HHT1 and HHT2 code for identical proteins),Null mutan\nt is viable\n mHHT2:Histone H3 (HHT1 and HHT2 code for identical proteins),histo\nne H3 (HHT1 and HHT2 code for identical proteins),\n mYBR089W:Unknown ,, Unknown\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n mASF1:anti-silencing protein that causes depression of silent loci\n when overexpressed,,\n mERP3:Emp24p/Erv25p related protein 2,p24 protein involved in memb\nrane trafficking,viable\n mERP5:Emp24p/Erv25p related protein 5,p24 protein involved in memb\nrane trafficking,viable\n Cond502:wtħ50nMaF,45minlog10(intensity)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond563:alpha84\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n  Science. 1998 Oct 23;282(5389):699-705.\n mCDC21:cell division cycle blocked at 36 degree C,thymidylate synth\nase,defective in continued replication during S phase of the\n cell cycle; temperature-sensitive thymidylate auxotroph\n mSMC3:involved in sister chromatid cohesion,SMC chromosomal ATPase\n family member,Null mutant is inviable\n Cond501:wt+/-50nMaF,30minlog10(intensity)\n mKCC4:involved in septin organization,S. pombe Nim1 homolog , prot\nein kinase,Null mutant is viable\n mHTA1:Histone H2A (HTA1 and HTA2 code for nearly identical protein\ns),histone H2A (HTA1 and HTA2 code for nearly identical prot\neins),Null mutant is viable\n mHTA2:Histone H2A (HTA1 and HTA2 code for nearly identical protein\ns),histone H2A (HTA1 and HTA2 code for nearly identical prot\neins),Null mutant is viable. Deletion of the HTA2-HTB2 (TRT2\n) locus has no reported observable phenotypes, presumably be\ncause HTA1-HTB1 (TRT1) expression is upregulated and can com\npensate in the absence of TRT2. Overexpression of TRT2 can s\nuppress Ty insertion mutations\n Cond554:alpha21\n mHCM1:Dosage-dependent suppressor of cmd1-1 mutation; shows homolo\ngy to fork head family of DNA-binding proteins,,Null mutant \nis viable; exacerbates temperature-sensitivity of a cmd1-1 (\ncalmodulin) mutant\n Cond738:90\n Cond575:cdc15_100\n mHHF1:Histone H4 (HHF1 and HHF2 code for identical proteins),histo\nne H4 (HHF1 and HHF2 code for identical proteins),\n mHHF2:Histone H4 (HHF1 and HHF2 code for identical proteins),histo\nne H4 (HHF1 and HHF2 code for identical proteins),\n Cond294:Itraconazole\n Cond574:cdc15_90\n mDUN1:DNA damage response,protein kinase,Null mutant is viable, de\nfective in DNA damage repair and in DNA damage-resposive ind\nuction of RNR genes, and sensitive to DNA damaging agents\n Cond747: mSPT21:involved in trascriptional regulation of Ty1 LTRs,non-specif\nic DNA binding protein,Null mutant is viable, spt21 mutation\ns suppress Ty insertion mutations\n Cond497:wtħ158nMaF,30minlog10(intensity)\n mHSL1:Negative regulator of swe1 kinase (which regulates cdc28),pr\notein kinase  (putative) , similar to S. pombe cdr1/nim1,Nul\nl mutant is viable; synthetically lethal with histone H3 mut\nations; G2 delay\n Cond560:alpha63\n Cond576:cdc15_110\n Cond736: Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond559:alpha56\n mSRL1:Suppressor of rad53 lethality,,\n mSWE1:protein kinase homolog,protein kinase homolog,Null mutant is\n viable\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n mHTB1:Histone H2B (HTB1 and HTB2 code for nearly identical protein\ns),histone H2B (HTB1 and HTB2 code for nearly identical prot\neins),Null mutant is viable\n Cond551:alpha0\n Cond549:clb2-2\n mHTB2:Histone H2B (HTB1 and HTB2 code for nearly identical protein\ns),histone H2B (HTB1 and HTB2 code for nearly identical prot\neins),Null mutant is viable. Deletion of the HTA2-HTB2 (TRT2\n) locus has no reported observable phenotypes, presumably be\ncause HTA1-HTB1 (TRT1) expression is upregulated and can com\npensate in the absence of TRT2\n mYOX1:Homeodomain protein that binds leu-tRNA gene,homeobox-domain\n containing protein,Null mutant is viable\n
Cond547:cln3-1\n Cond498:wtħ500nMaF,30minlog10(intensity)\n mMCD1:Mitotic Chromosome Determinant; similar to S. pombe RAD21; m\nay function in chromosome morphogenesis from S phase through\n mitosis,,Null mutant is inviable; temperature sensitive mut\nants are defective in mitotic sister chromatid cohesion and \nmitotic chromosome condensation; multicopy suppressor of smc\n1-2 mutation\n mPOL1:Required for mitotic DNA synthesis, premeiotic DNA synthesis\n, recombination, and full sporulation,DNA polymerase I alpha\n subunit p180,Null mutant is inviable. pol1(ts) mutants show\n blocked cell division at 36 degrees C\n Cond541:fus3D+50nMaF,30min/wtlog10(intensity)\n mTOS4:Hypothetical ORF,,\n Cond494:wtħ5nMaF,30minlog10(intensity)\n Cond565:alpha98\n Cond798:Ca30'\n Cond548:cln3-2\n Cond578:cdc15_130\n Cond500:wtħ50nMaF,15minlog10(intensity)\n Cond751: Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond735: Cond740: Cond513:GAL-STE11-4,3hrs.gallog10(intensity)\n Cond504:wtħ50nMaF,90minlog10(intensity)\n mCLB5:role in DNA replication during S phase; additional functiona\nl role in formation of mitotic spindles along with Clb3 and \nClb4,B-type cyclin,Null mutant is viable, but has an extende\nd S phase\n mYBR070C:Unknown ,, Unknown\n Cond579:cdc15_140\n mCLB6:role in DNA replication during S phase,B-type cyclin,Null mu\ntant is viable\n Cond561:alpha70\n mMNN1:Alpha-1,3-mannosyltransferase,alpha-1,3-mannosyltransferase,\nNull mutant is viable\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond573:cdc15_80\n Cond519:rst1Drst2Dħ50nMaF,30minlog10(intensity)\n mYLR049C:Unknown ,, Unknown\n mCDC6:Protein involved in initiation of DNA replication,pre-initia\ntion complex component,arrest at initiation of S phase\n Cond505:wtħ50nMaF,120minlog10(intensity)\n mCDC47:Essential for initiation of DNA replication,,Null mutant is \ninviable, at nonpermissive temperature cdc47(ts) mutants arr\nest with a large bud and a single nucleus\n Cond733: Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n Cond562:alpha77\n Cond496:wtħ50nMaF,30minlog10(intensity)\n mCLN1:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest\n Cond748: mCLN2:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest; dominant mutation advances the G(sub)1- to\n S- phase transition and impairs ability of cells to arrest \nin G(sub)1 phase in response to external signals\n Cond805:Ca/Ca+FK30'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Cond530:GAL-BNI1D,3hrs.gallog10(intensity)\n Cond568:alpha119\n Cond753: mYCL022C:Unknown ,, Unknown\n mYPL267W:Unknown ,, Unknown\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n Cond279:ERG11(tetpromoter)\n mMCM3:Member of complex that acts at ARS's to initiate replication\n,,Null mutant is inviable, at nonpermissive temperature mcm3\n(ts) mutants arrest with a large bud and a single nucleus an\nd exhibit a high rate of recombination; mcm3 mutants are def\nective in minichromosome maintenance; mcm3-1 cdc45-1 mutants\n are synthetically lethal\n Cond553:alpha14\n Cond752: Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n Cond749: Cond557:alpha42\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Cond580:cdc15_150\n Cond65:fus3(haploid)\n mYOR066W:Unknown ,, Unknown\n Cond797:Ca15'\n Cond502:wtħ50nMaF,45minlog10(intensity)\n Cond54:erg3(haploid)\n Cond581:cdc15_160\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond563:alpha84\n Cond572:cdc15_70\n Cond558:alpha49\n mYOR263C:Unknown ,, Unknown\n Cond734: Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n mYGP1:may be involved in cellular adaptations prior to stationary \nphase,gp37, a glycoprotein synthesized in response to nutrie\nnt limitation which is homologous to the sporulation-specifi\nc SPS100 gene,\n mCDC21:cell division cycle blocked at 36 degree C,thymidylate synth\nase,defective in continued replication during S phase of the\n cell cycle; temperature-sensitive thymidylate auxotroph\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond501:wt+/-50nMaF,30minlog10(intensity)\n mKCC4:involved in septin organization,S. pombe Nim1 homolog , prot\nein kinase,Null mutant is viable\n mYJL195C:Unknown ,, Unknown\n Cond554:alpha21\n mENB1:Siderophore transporter for enterobactin; AFT1 regulon,enter\nobactin transporter,Null mutants are viable but are unable t\no take up and utilize iron from enterobactin\n Cond738:90\n Cond571:cdc15_50\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond737: Cond747: Cond366:dtt_120_min_dtt-2\n Cond497:wtħ158nMaF,30minlog10(intensity)\n Cond560:alpha63\n Cond576:cdc15_110\n Cond555:alpha28\n Cond493:wtħ1.5nMaF,30minlog10(intensity)\n mDSE3:Hypothetical ORF,,\n mSVS1:involved in vanadate resistance,,Null mutant is viable, show\ns increased sensitivity to vanadate, but not other metallic \nions or drugs\n Cond570:cdc15_30\n mRNR1:ribonucleotide reductase,ribonucleotide reductase, large (R1\n) subunit,Null mutant is inviable\n Cond736: Cond503:wtħ50nMaF,60minlog10(intensity)\n Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond559:alpha56\n mYRO2:Homolog to HSP30 heat shock protein Yro1p,,\n mSWE1:protein kinase homolog,protein kinase homolog,Null mutant is\n viable\n Cond750: Cond510:fus3Dħ50nMaF,30minlog10(intensity)\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n mHTB1:Histone H2B (HTB1 and HTB2 code for nearly identical protein\ns),histone H2B (HTB1 and HTB2 code for nearly identical prot\neins),Null mutant is viable\n Cond551:alpha0\n Cond549:clb2-2\n mYOX1:Homeodomain protein that binds leu-tRNA gene,homeobox-domain\n containing protein,Null mutant is viable\n mCDC47 mMCM3
Cond547:cln3-1\n Cond498:wtħ500nMaF,30minlog10(intensity)\n mMCD1:Mitotic Chromosome Determinant; similar to S. pombe RAD21; m\nay function in chromosome morphogenesis from S phase through\n mitosis,,Null mutant is inviable; temperature sensitive mut\nants are defective in mitotic sister chromatid cohesion and \nmitotic chromosome condensation; multicopy suppressor of smc\n1-2 mutation\n mTOS2:Hypothetical ORF,,\n mAXL2:involved in polarity establishment/cellular polarization dur\ning budding,,AXL2 can serve as a multicopy suppressor of rho\n3 and is required for the haploid axial budding pattern of S\n. cerevisiae.\n mTOS4:Hypothetical ORF,,\n Cond494:wtħ5nMaF,30minlog10(intensity)\n mTOS7:Hypothetical ORF,,\n Cond548:cln3-2\n Cond578:cdc15_130\n mASH1:Zinc-finger inhibitor of HO transcription which is asymmetri\ncally localized to the daughter cell nucleus,,Mutant ash1 da\nughters can transcribe HO and switch mating type\n Cond500:wtħ50nMaF,15minlog10(intensity)\n Cond751: mEGT2:cell-cycle regulation protein, may be involved in the correc\nt timing of cell separation after cytokinesis,,\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond585:cdc15_200\n Cond740: mYIL141W:Unknown ,, Unknown\n Cond224:CMD1(tetpromoter)\n mBUD9:among a group of genes whose products are necessary for bud-\nsite selection; likely involvement in positioning the proxim\nal pole signal,,In null mutants bipolar-budding cells bud pr\neferentially at distal pole\n Cond504:wtħ50nMaF,90minlog10(intensity)\n mCLB5:role in DNA replication during S phase; additional functiona\nl role in formation of mitotic spindles along with Clb3 and \nClb4,B-type cyclin,Null mutant is viable, but has an extende\nd S phase\n mYBR070C:Unknown ,, Unknown\n Cond579:cdc15_140\n mCLB6:role in DNA replication during S phase,B-type cyclin,Null mu\ntant is viable\n mNIS1:Hypothetical ORF,,\n Cond556:alpha35\n Cond561:alpha70\n mRFA1:Required for DNA-damage repair, full levels of gene conversi\non and sporulation,heterotrimeric RPA (RF-A) single-stranded\n DNA binding protein 69 kDa subunit; binds URS1 and CAR1,Nul\nl mutant is inviable; cells lacking RFA1 accumulate as multi\nply budded cells with a single nucleus suggesting a defect i\nn DNA replication; rfa1 repair defects are suppressed by hig\nh copy RAD52\n mYPL158C:Unknown ,, Unknown\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond573:cdc15_80\n mYLR049C:Unknown ,, Unknown\n Cond586:cdc15_210\n mPOL12:Required for DNA synthesis and correct progression through S\n phase; plays an essential role at early stage of chromosoma\nl DNA replication, before the hydroxyurea-sensitive step,DNA\n polymerase alpha-primase complex B subunit,Null mutant is i\nnviable\n mPST1:Protoplasts-secreted,the gene product has been detected amon\ng the proteins secreted by regenerating protoplasts,Viable\n Cond733: Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n mYLR194C:Unknown ,, Unknown\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n mHSP150:Heat shock protein, secretory glycoprotein,heat shock protei\nn , secretory glycoprotein , heat shock protein , secretory \nglycoprotein , heat shock protein , secretory glycoprotein,N\null mutant is viable\n Cond562:alpha77\n Cond496:wtħ50nMaF,30minlog10(intensity)\n mCLN1:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest\n mCLN2:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest; dominant mutation advances the G(sub)1- to\n S- phase transition and impairs ability of cells to arrest \nin G(sub)1 phase in response to external signals\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n mPMS1:Required for mismatch repair in mitosis and meiosis, low lev\nels of postmeiotic segregation, and high spore viability, di\nspensable for homeologous recombination,mutL homolog , simil\nar to Mlh1p, associates with Mlh1p, possibly forming a heter\nodimer, Pms1p and Msh1p act in concert to bind to a Msh2p-he\nteroduplex complex containing a G-T mismatch,Null mutant is \nviable; postmeiotic segregation increased\n mCRH1:congo red hypersensitive,cell wall protein,Null mutant is vi\nable and hypersensitive to Congo Red and Calcofluor White\n mYKR077W:Unknown ,, Unknown\n Cond753: mYCL022C:Unknown ,, Unknown\n mYPL267W:Unknown ,, Unknown\n mCSI2:chitin synthase involved,chitin synthase 3 complex structura\nl component (putative),Null mutant is viable but shows deloc\nalized chitin deposition\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n Cond553:alpha14\n Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n Cond749: mMSH2:Functions with Pms1p and Pms2/Mlh1p in a complex that intera\ncts with Pms3p/Msh6p to repair single-base and insertion-del\netion mispairs, or Msh3p to repair insertion-deletion mispai\nrs.,mutS homolog,Null mutant is viable. Haploid mutants disp\nlay an 85-fold increased rate of spontaneous mutation to can\navanine resistance. Mutants are defective for gene conversio\nn polarity gradients and high spore viability.\n Cond176:swi5\n Cond557:alpha42\n mMSH6:Required for mismatch repair in mitosis & meiosis, low level\ns of postmeiotic segregation & high spore viability; forms c\nomplex with Msh2p to repair both single-base & insertion-del\netion mispairs; redundant with Msh3p in repair of in-dels,hu\nman GTBP protein homolog,Null mutant is viable, msh3 msh6 do\nuble deletion mutants exhibit microsatellite instability and\n mutability similar to that in a msh2 mutant\n mYBR089W:Unknown ,, Unknown\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Cond580:cdc15_150\n mPRI2:p58 polypeptide of DNA primase,DNA primase p58 polypeptide,l\nethal\n mCHS1:disrupts mating and sporulation efficiently,chitin synthase \n1,Null mutant is viable\n mSIC1:P40 inhibitor of Cdc28p-Clb5 protein kinase complex,,Null mu\ntant is viable, shows increased frequency of broken and lost\n chromosomes; sic1 deletion mutant rescues lethality of cln1\n cln2 cln3 triple mutant.\n mYBR071W:Unknown ,, Unknown\n Cond502:wtħ50nMaF,45minlog10(intensity)\n Cond54:erg3(haploid)\n Cond581:cdc15_160\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond563:alpha84\n Cond558:alpha49\n Cond734: Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond582:cdc15_170\n Cond653:wt_plus_gamma_30_min\n Cond501:wt+/-50nMaF,30minlog10(intensity)\n mKCC4:involved in septin organization,S. pombe Nim1 homolog , prot\nein kinase,Null mutant is viable\n mPCL2:Interacts with cyclin-dependent kinase PHO85 to form kinase \ncomplex with G1-periodic activity involved in cell cycle pro\ngression,G1 cyclin,\n Cond554:alpha21\n Cond738:90\n mPOL30:Accessory factor for DNA polymerase delta, mRNA increases in\n G1, peaks in S in mitosis, & increases prior to DNA synthes\nis in meiosis; required for DNA replication & repair, requir\ned for viability in cdc44, rad50, rad52 or rad57 backgrounds\n,,Null mutant is inviable\n Cond571:cdc15_50\n Cond575:cdc15_100\n mRSR1:Gtp-binding protein of the ras superfamily involved in bud s\nite selection,,random budding pattern\n mPCL9:PHO85 cyclin,,Null mutant is viable.\n Cond574:cdc15_90\n Cond737: mCTS1:Endochitinase,endochitinase,Null mutant is viable; exhibits \na defect in cell separation\n Cond747: mSPT21:involved in trascriptional regulation of Ty1 LTRs,non-specif\nic DNA binding protein,Null mutant is viable, spt21 mutation\ns suppress Ty insertion mutations\n Cond497:wtħ158nMaF,30minlog10(intensity)\n Cond560:alpha63\n Cond576:cdc15_110\n mDSE3:Hypothetical ORF,,\n mDSE4:Hypothetical ORF,,\n Cond570:cdc15_30\n Cond736: Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Cond584:cdc15_190\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond559:alpha56\n mFAA3:acyl-CoA synthetase (long-chain fatty acid CoA ligase) (fatt\ny acid activator 3), activates endogenous but not imported f\natty acids and provides substrates for N-myristoylation,acyl\n-CoA synthase,Not essential for vegetative growth when fatty\n acid synthase (fas) is active\n Cond750: Cond567:alpha112\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n mPIR1:Protein containing tandem internal repeats,contains tandem i\nnternal repeats,Null mutant is viable; pir1 hsp150 (pir2) do\nuble mutant and pir1 hsp150 (pir2) pir3 triple mutant are sl\now-growing on agar slab and sensitive to heat shock\n Cond551:alpha0\n Cond549:clb2-2\n mYOX1:Homeodomain protein that binds leu-tRNA gene,homeobox-domain\n containing protein,Null mutant is viable\n mPIR3:Protein containing tandem internal repeats,contains tandem i\nnternal repeats,Null mutant is viable; pir1 hsp150 (pir2) pi\nr3 triple mutant is slow-growing on agar slab and sensitive \nto heat shock\n mMSH6 mPMS1 mMSH2 mSIC1 mCLB5
Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n Cond796:Ca5'\n Cond221:yer083c\n Cond798:Ca30'\n Cond432:YPD_stationary_phase_22_d_ypd-1\n Cond649:dun1-_+_0.02%_MMS_-_120_min\n Cond751: Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns.  J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond362:dtt_000_min__dtt-2\n mCLB1:Involved in mitotic induction,B-type cyclin,Null mutant is v\niable (lethal in combination with clb2 mutation)\n Cond761:Heat_30'\n Cond400:Nitrogen_Depletion_12_h\n mCLB2:Involved in mitotic induction,B-type cyclin,Null mutant is v\niable (lethal in combination with clb1 mutation)\n Cond648:dun1-_+_0.02%_MMS_-_90_min\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYJL051W:Unknown ,, Unknown\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond810:Na45'\n Cond911:(83i5)_S150-2B_YPD_NormInt\n Cond637:DES460_+_0.02%_MMS_-_60_min\n Cond505:wtħ50nMaF,120minlog10(intensity)\n mCDC47:Essential for initiation of DNA replication,,Null mutant is \ninviable, at nonpermissive temperature cdc47(ts) mutants arr\nest with a large bud and a single nucleus\n Cond724:t4+SSD1,H44\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond805:Ca/Ca+FK30'\n Cond769:Acid_80'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Cond530:GAL-BNI1D,3hrs.gallog10(intensity)\n Cond429:YPD_stationary_phase_5_d_ypd-1\n Cond568:alpha119\n Cond279:ERG11(tetpromoter)\n Cond793:Sorbitol_90'\n Cond553:alpha14\n Cond752: Cond404:Nitrogen_Depletion_5_d\n Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n Cond580:cdc15_150\n Cond797:Ca15'\n Cond777:msn2/4_acid_0'\n Cond767:Acid_40'\n Cond684:pRS-ROX1_GAL_media\n Cond581:cdc15_160\n Cond54:erg3(haploid)\n Cond558:alpha49\n mYLR057W:Unknown ,, Unknown\n Cond358:2.5mM_DTT_060_min_dtt-1\n Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond582:cdc15_170\n Cond433:YPD_stationary_phase_28_d_ypd-1\n Cond571:cdc15_50\n Cond809:Na30'\n Cond645:DES459_(mec1-)_+_0.02%_MMS_-_90_min\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n mSUN4:Protein involved in the aging process,,\n Cond366:dtt_120_min_dtt-2\n Cond555:alpha28\n Cond813:Na+FK30'\n Cond636:DES460_+_0.2%_MMS_-_45_min\n Cond570:cdc15_30\n Cond639:DES460_+_0.02%_MMS_-_120_min\n Cond503:wtħ50nMaF,60minlog10(intensity)\n Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Cond441:DBYmsn2/4_(real_strain)_+_0.32_mM_H2O2_(20_min)\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n mMYO1:myosin class II,class II myosin,Null mutant is viable, exhib\nts abnormal chitin distribution and cell wall organization a\nt the mother-bud neck in a high proportion of dividing cells\n; exhibits abberant nuclear migration and cytokinesis; bem2 \nmyo1 double mutants are inviable\n Cond567:alpha112\n mYOR315W:Unknown ,, Unknown\n Cond652:wt_plus_gamma_20_min\n Cond907:(83i1)_S150-2B_YPGL_NormInt\n mSWI5:transcriptional activator,transcriptional activator,homothal\nlic switching deficient\n Calcin.CaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond552:alpha7\n Cond440:DBYmsn2msn4_(good_strain)_+_0.32_mM_H2O2\n Cond782:Peroxide_40'\n Cond770:Acid_100'\n Cond504:wtħ50nMaF,90minlog10(intensity)\n Cond647:dun1-_+_0.02%_MMs_-_30_min\n Cond800:CaFK5'\n Y-Stre.msn2/4acid:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond586:cdc15_210\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond375:1.5_mM_diamide_(60_min)\n Cond656:wt_plus_gamma_90_min\n Stress.DTT1:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Y-Stre.Acid:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond940:6h\n Cond638:DES460_+_0.02%_MMS_-_90_min\n Cond635:DES460_+_0.02%_MMS_-_30_min\n Cond566:alpha105\n Cond357:2.5mM_DTT_045_min_dtt-1\n Cond340:constant_0.32_mM_H2O2_(60_min)_redo\n Cond768:Acid_60'\n Cond646:DES459_(mec1-)_+_0.02%_MMS_-_120_min\n Cond550:clb2-1\n Cond557:alpha42\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Cond434:DBY7286_37degree_heat_-_20_min\n Cond794:Intertic\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond783:Peroxide_60'\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond502:wtħ50nMaF,45minlog10(intensity)\n Cond563:alpha84\n Cond359:2.5mM_DTT_090_min_dtt-1\n mCDC20:Required for onset of anaphase,anaphase promoting complex (A\nPC) subunit,Null mutant is inviable; conditional alleles sho\nw cell cycle arrest in G2\n Cond175:swi4\n Y-Stre.Sorbitol:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond779:msn2/4_acid_20'\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond403:Nitrogen_Depletion_3_d\n Cond766:Acid_20'\n Cond250:ymr031w-a\n Cond402:Nitrogen_Depletion_2_d\n Cond554:alpha21\n Cond811:Na60'\n Cond575:cdc15_100\n Cond283:KAR2(tetpromoter)\n Cond336:constant_0.32_mM_H2O2_(20_min)_redo\n Cond360:2.5mM_DTT_120_min_dtt-1\n Cond401:Nitrogen_Depletion_1_d\n mYIL158W:Unknown ,, Unknown\n Cond574:cdc15_90\n Cond380:1M_sorbitol_-_45_min_\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond747: Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond560:alpha63\n Cond576:cdc15_110\n Cond442:DBYyap1-_+_0.3_mM_H2O2_(20_min)\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast.  Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond339:constant_0.32_mM_H2O2_(50_min)_redo\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond559:alpha56\n Y-Stre.Peroxide:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond514:GAL-STE12,3hrs.gallog10(intensity)\n Cond428:YPD_stationary_phase_3_d_ypd-1\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n Cond551:alpha0\n Cond549:clb2-2\n Cond939:4h\n
Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n Cond498:wtħ500nMaF,30minlog10(intensity)\n Cond755: Cond541:fus3D+50nMaF,30min/wtlog10(intensity)\n Cond476:GCN4C/GCN4(R4760/R6257)\n Cond494:wtħ5nMaF,30minlog10(intensity)\n Cond565:alpha98\n Cond548:cln3-2\n Cond535:tec1D+50nMaF/wt+50nMaF,120minlog10(intensity)\n Cond744: Cond751: Cond675:MHY1_(dun1)_+_heat_20_min\n Cond121:qcr2(haploid)\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns.  J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond533:fus3D+50nMaF/wt+50nMaF,30minlog10(intensity)\n Cond400:Nitrogen_Depletion_12_h\n Cond735: Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond730:hda1\n Cond579:cdc15_140\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond505:wtħ50nMaF,120minlog10(intensity)\n Cond522:fus3Dkss1D/wtlog10(intensity)\n Cond916:(99i5)__HBY4_YPGL+G_NormInt\n Cond562:alpha77\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond166:ste11(haploid)\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n mYLR042C:Unknown ,, Unknown\n Cond376:1.5_mM_diamide_(90_min)\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond429:YPD_stationary_phase_5_d_ypd-1\n Cond568:alpha119\n Cond523:ste4D/wtlog10(intensity)\n mPDS5:Precocious Dissociation of Sister chromatids,,\n Cond279:ERG11(tetpromoter)\n Cond793:Sorbitol_90'\n Cond553:alpha14\n Cond752: Cond404:Nitrogen_Depletion_5_d\n Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n Cond216:yer044c(haploid)\n Cond807:crz1/Ca30'\n Cond524:ste5D/wtlog10(intensity)\n Cond226:yhl029c\n Cond580:cdc15_150\n Cond65:fus3(haploid)\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond54:erg3(haploid)\n Cond581:cdc15_160\n Cond385:Hypo-osmotic_shock_-_15_min\n Cond558:alpha49\n Cond734: Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n Cond945:W303_YPD\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond582:cdc15_170\n Cond314:Heat_Shock_060_minutes__hs-2\n Cond781:Peroxide_20'\n Cond691:gal5+gal\n Cond41:dig1,dig2(haploid)\n Cond571:cdc15_50\n Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n Cond92:kin3\n Cond645:DES459_(mec1-)_+_0.02%_MMS_-_90_min\n Cond737: Cond742: Cond66:fus3,kss1(haploid)\n Cond754: Calcin.crz1:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond555:alpha28\n mMSB2:putative integral membrane protein,integral membrane protein\n (putative),multicopy suppressor of cdc24 ts mutation\n Cond173:ste5(haploid)\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n  Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n mRNR1:ribonucleotide reductase,ribonucleotide reductase, large (R1\n) subunit,Null mutant is inviable\n Cond503:wtħ50nMaF,60minlog10(intensity)\n Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Cond564:alpha91\n Cond347:1_mM_Menadione_(30_min)_redo\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n Cond40:dig1,dig2\n Cond526:ste11D/wtlog10(intensity)\n Cond332:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_5_minutes\n Cond547:cln3-1\n Cond368:dtt_480_min_dtt-2\n mTOS4:Hypothetical ORF,,\n mTOS6:Hypothetical ORF,,\n Cond500:wtħ50nMaF,15minlog10(intensity)\n Cond552:alpha7\n Cond93:kre1\n Cond337:constant_0.32_mM_H2O2_(30_min)_redo\n Cond782:Peroxide_40'\n Cond504:wtħ50nMaF,90minlog10(intensity)\n Cond172:ste4(haploid)\n Cond519:rst1Drst2Dħ50nMaF,30minlog10(intensity)\n Cond745: Cond516:rst1Drst2D/wtlog10(intensity)\n Cond28:cla4(haploid)\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt.  Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond384:Hypo-osmotic_shock_-_5_min\n Y-Stre.Acid:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond525:ste7D/wtlog10(intensity)\n Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n Cond739: Cond496:wtħ50nMaF,30minlog10(intensity)\n mCLN1:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n Cond753: mCSI2:chitin synthase involved,chitin synthase 3 complex structura\nl component (putative),Null mutant is viable but shows deloc\nalized chitin deposition\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond489:PHO81c_vs_WT_exp1\n Cond768:Acid_60'\n Cond756: Cond550:clb2-1\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Cond434:DBY7286_37degree_heat_-_20_min\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast.  Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond528:ste18D/wtlog10(intensity)\n Cond278:CDC42(tetpromoter)\n Cond333:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_15_minutes\n Cond502:wtħ50nMaF,45minlog10(intensity)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond563:alpha84\n Cond527:ste12D/wtlog10(intensity)\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Cond946:W303ume6_YPD\n Cond666:mec1_plus_gamma_45_min\n Stress.Menadione:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond175:swi4\n Y-Stre.Sorbitol:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond806:crz1/Ca15'\n Cond403:Nitrogen_Depletion_3_d\n Cond250:ymr031w-a\n Cond501:wt+/-50nMaF,30minlog10(intensity)\n Cond402:Nitrogen_Depletion_2_d\n Cond554:alpha21\n Cond738:90\n Cond732:fkh1,2_alpha_factor_000_min_y12n57\n Cond743: Cond401:Nitrogen_Depletion_1_d\n Cond534:tec1D+50nMaF/wt+50nMaF,30minlog10(intensity)\n Cond167:ste12(haploid)\n Cond294:Itraconazole\n pho.Pho:New components of a system for phosphate accumulation and po\nlyphosphate metabolism in Saccharomyces cerevisiae revealed \nby genomic expression analysis.  Mol Biol Cell. 2000 Dec;11(\n12):4309-21.\n mTOS11:Hypothetical ORF,,\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond474:gcn4D+/-100mM3AT(KNY124)\n Cond348:1mM_Menadione_(40_min)_redo\n Cond538:fus3D/wtlog10(intensity)\n Cond747: Cond497:wtħ158nMaF,30minlog10(intensity)\n Cond560:alpha63\n Cond168:ste18(haploid)\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast.  Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond274:yor080w(**3)\n mHSL7:Negative regulator of swe1 kinase (which regulates cdc28),,N\null mutant is viable; synthetically lethal with histone H3 m\nutations; G2 delay\n Cond174:ste7(haploid)\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond559:alpha56\n mSRL1:Suppressor of rad53 lethality,,\n Y-Stre.Peroxide:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond521:fus3-K42Dħ50nMaF,30minlog10(intensity)\n Cond307:Heat_Shock_80_minutes_hs-1\n Cond428:YPD_stationary_phase_3_d_ypd-1\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n Cond551:alpha0\n Cond549:clb2-2\n mYOX1:Homeodomain protein that binds leu-tRNA gene,homeobox-domain\n containing protein,Null mutant is viable\n

this is an automaticly generated GENESYS report
Computational Genomics Lab, Tel-Aviv uniresity