Module amino_acid_biosynthesis




Database revision : gnsdb28.10
Date : Fri Feb 28 01:36:32 2003
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mHIS3:imidazoleglycerol-phosphate dehydratase,imidazoleglycerol-ph\nosphate dehydratase,Null mutant is viable and requires histi\ndine\n Cond158:sir2\n mHIS4:histidinol dehydrogenase,histidinol dehydrogenase,Null mutan\nt is viable and requires histidine\n Cond277:AUR1(tetpromoter)\n mHIS5:responsive to control of general amino acid biosynthesis,his\ntidinol-phosphate aminotransferase,Null mutant is viable and\n requires histidine\n Cond476:GCN4C/GCN4(R4760/R6257)\n mHIS7:glutamine amidotransferase:cyclase, also called imidazole gl\nycerol phosphate synthase,glutamine amidotransferase:cyclase\n , imidazole glycerol phosphate synthase (synonym),Null muta\nnt is viable and requires histidine\n Cond221:yer083c\n Cond104:npr2\n mSIP4:Possibly involved in Snf1p regulated transcriptional activat\nion,,\n mMCH1:Unknown ,, Unknown\n Cond164:sst2(haploid)\n mMCH4:Unknown ,, Unknown\n Cond95:mac1\n Cond13:ase1(**12)\n mYOR203W:Unknown ,, Unknown\n Cond730:hda1\n mYGR110W:Unknown ,, Unknown\n Cond244:ymr010w\n mSUL1:Putative sulfate permease,,Null mutant is viable, unable to \ngrow on media containing less than 5 mM sulphate\n mCTF13:58 kd component (Cbf3c) of the multisubunit 'Cbf3' kinetocho\nre protein complex, which binds to the CDE III element of ce\nntromeres,,Null mutant is inviable\n mSUL2:Sulfate uptake,high affinity sulfate permease,\n Cond30:clb6\n Cond391:aa_starv_1_h\n mFRM2:Protein involved in the integration of lipid signaling pathw\nays with cellular homeostatis,,Null mutant is viable and sen\nsitive to arachidonic acid\n Cond517:sst2D/wtlog10(intensity)\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond245:ymr014w\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond184:ubr1\n mVID24:also involved in vacuolar protein targeting,peripheral vesic\nle membrane protein,Null mutant is viable, defective in fruc\ntose-1,6-bisphosphatase dergadation\n Cond123:rad57\n mYHR162W:Unknown ,, Unknown\n Cond279:ERG11(tetpromoter)\n Cond247:ymr029c\n mPEX21:Peroxin; Pex18p and Pex21p are partially functionally redund\nant.,peroxin,Null mutant is viable.\n Cond216:yer044c(haploid)\n Cond86:imp2'(**12)\n Cond479:WT+/-100mM3AT(SetD)(R491)\n mTEA1:Mutants are defective in Ty1 Enhancer-mediated Activation,,D\niminished Ty1 expression\n mICY2:Interacting with the cytoskeleton,,\n Cond57:erg6\n mLYS1:saccharopine dehydrogenase,,Lysine requiring\n Cond226:yhl029c\n Cond482:WT+/-100mM3AT(SetC)(KNY164)\n Cond194:yap1\n mLYS2:alpha aminoadipate reductase,alpha aminoadipate reductase,Nu\nll mutant is viable, lysine auxotroph\n mADH5:alcohol dehydrogenase isoenzyme V,alcohol dehydrogenase isoe\nnzyme V,\n mTRP2:anthranilate synthase Component I,anthranilate synthase comp\nonent I,tryptophan requiring\n mTRP3:anthranilate synthase Component II and indole-3-phosphate (m\nultifunctional enzyme),anthranilate synthase component II , \nindole-3-phosphate,Null mutant is viable, tryptophan auxotro\nph\n mTRP4:anthranilate phosphoribosyl transferase,anthranilate phospho\nribosyl transferase,tryptophan requiring\n Cond145:rts1\n mTRP5:tryptophan synthetase,tryptophan synthetase,Null mutant is v\niable and requires tryptophan\n mSNZ1:Snooze: stationary phase-induced gene family; may be involve\nd in cellular response to nutrient limitation and growth arr\nest,highly conserved 35 kDa protein that shows increased exp\nression after entry into stationary phase,Null mutant is via\nble, sensitive to 6-azauracil and methylene blue.\n Cond71:gln3\n Cond88:isw1,isw2\n Cond481:WT+/-100mM3AT(SetB)(491)\n Cond54:erg3(haploid)\n Cond233:yhr039c\n mILV2:acetolactate synthase,acetolactate synthase,Isoleucine-plus-\nvaline requiring; Sulfometuron methyl resistance\n Cond68:gas1\n mILV3:catalyzes third step in common pathway leading to biosynthes\nis of branched-chain amino acids,dihydroxyacid dehydratase,N\null mutant is viable and requires isoleucine and valine\n Cond116:pex12\n Cond143:rrp6\n mBOP2:bypass of PAM1,,\n mYLR152C:Unknown ,, Unknown\n Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n Cond26:cka2\n mILV6:acetolactate synthase regulatory subunit,,\n Cond69:gcn4\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYJL213W:Unknown ,, Unknown\n Cond108:pac2\n mYNL129W:Unknown ,, Unknown\n Cond27:ckb2\n Cond731:hda1
\n Cond73:gyp1\n Cond162:spf1\n mECM17:ExtraCellular Mutant,sulfite reductase (putative),loss of fu\nnction mutants are methionine requiring and sensitive to the\n cell wall perturbing agent calcoflour white.\n Cond634:DES460_+_0.02%_MMS_-_15_min\n Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n mRIB3:Riboflavin biosynthesis,3,4-dihydroxy-2-butanone 4-phosphate\n synthase,\n Cond25:cin5\n mRIB5:Riboflavin biosynthesis,,Null mutant is viable, exhibits rib\noflavin auxotrophy\n mYGL117W:Unknown ,, Unknown\n mIDP1:Mitochondrial form of NADP-specific isocitrate dehydrogenase\n,NADP-dependent isocitrate dehydrogenase,Null mutant is viab\nle\n mYMC1:putative mitochondrial carrier protein,carrier protein (puta\ntive),\n mBAT1:branched-chain amino acid transaminase, highly similar to ma\nmmalian ECA39, which is regulated by the oncogene myc,branch\ned-chain amino acid transaminase , highly similar to mammali\nan ECA39, which is regulated by the oncogene myc , branched-\nchain amino acid transaminase , highly similar to mammalian \nECA39, which is regulated by the oncogene myc,Null mutant is\n viable; ILV auxotrophy in bat1 bat2 double mutant\n mBAT2:Branched-Chain Amino Acid Transaminase,branched-chain amino \nacid transaminase,Null mutant is viable; ILV auxotrophy in b\nat1 bat2 double mutants\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n  Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n mPOS5:involved in oxidative stress,,pos5 mutants are peroxide sens\nitive\n mVHT1:vitamin H transporter,H+-biotin symporter,reduced biotin upt\nake, reduced levels of protein biotinylation\n Cond39:dig1\n Cond160:sir4\n Cond135:rpl20a\n mCPA1:Carbamoyl phosphate synthetase, arginine specific,arginine s\npecific , carbamoyl phosphate synthetase,Null mutant is viab\nle\n mYJL200C:Unknown ,, Unknown\n mCPA2:carbamyl phosphate synthetase,carbamyl phosphate synthetase,\nNull mutant is viable\n mMTG1:Unknown ,, Unknown\n Cond477:GCN4/gcn4Din100mM3AT(KNY164/KNY124)\n mURA10:Fifth step in pyrimidine bio5,orotate phosphoribosyltransfer\nase 2,Null mutant is viable\n Cond397:Nitrogen_Depletion_2_h\n mARG1:arginosuccinate synthetase,arginosuccinate synthetase,Argini\nne requiring\n mHOM2:threonine and methionine pathway,aspartic beta semi-aldehyde\n dehydrogenase,Homoserine requiring\n mARG3:Sixth step in arginine biosynthesis,ornithine carbamoyltrans\nferase,Arginine requiring\n Cond396:Nitrogen_Depletion_1_h\n Cond225:yhl013c\n mHOM3:First step in common pathway for methionine and threonine bi\nosynthesis,aspartate kinase (L-aspartate 4-P-transferase) (E\nC 2.7.2.4),Homoserine requiring; Borrelidin resistance\n mARG4:argininosuccinate lyase,argininosuccinate lyase,Arginine req\nuiring\n mLYS20:homocitrate synthase, highly homologous to YDL131W,YDL131W (\nLYS21) homolog , homocitrate synthase,Null mutant is viable,\n is able to grow on minimal media, and exhibits reduced but \nsignificant homocitrate synthase activity\n Cond260:ymr237w\n mLYS21:homocitrate synthase, highly homologous to YDL182W,YDL182W (\nLYS20) homolog , homocitrate synthase,\n mSTR2:Sulfur TRansfer,cystathionine gamma-synthase,Null mutant is \nviable but unable to turn cysteine into homocysteine. Grows \nwhen supplied with cystathionine.\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n mSTR3:Sulfur TRansfer,cystathionine beta-lyase,Null mutant is viab\nle but unable to turn cysteine into homocysteine. No growth \nwhen supplied with cystathionine.\n mARG8:Acetylornithine aminotransferase,acetylornithine aminotransf\nerase,Arginine requiring\n mSSU1:sensitive to sulfite,major facilitator superfamily,Null muta\nnt is viable; sulfite sensitive\n Cond29:clb2\n Cond89:isw2\n mARG5,6:N-acetyl-gamma-glutamyl-phosphate reductase and acetylglutam\nate kinase,N-acetyl-gamma-glutamyl-phosphate reductase and a\ncetylglutamate kinase,Arginine requiring\n Cond224:CMD1(tetpromoter)\n Cond647:dun1-_+_0.02%_MMs_-_30_min\n mARO1:pentafunctional arom polypeptide (contains: 3-dehydroquinate\n synthase, 3-dehydroquinate dehydratase (3-dehydroquinase), \nshikimate 5-dehydrogenase, shikimate kinase, and epsp syntha\nse),3-dehydroquinate dehydratase (3-dehydroquinase) , 3-dehy\ndroquinate synthase , epsp synthase , pentafunctional arom p\nolypeptide , shikimate 5-dehydrogenase , shikimate kinase,ar\nomatic amino acid requiring; lack of premeiotic DNA synthesi\ns; blocked sporulation in homozygous mutant\n Cond190:vps8\n mARO3:DAHP synthase; a.k.a. phospho-2-dehydro-3-deoxyheptonate ald\nolase, phenylalanine-inhibited; phospho-2-keto-3-deoxyhepton\nate aldolase; 2-dehydro-3-deoxyphosphoheptonate aldolase; 3-\ndeoxy-D-arabine-heptulosonate-7-phosphate synthase,DAHP synt\nhase; a.k.a. phospho-2-dehydro-3-deoxyheptonate aldolase, ph\nenylalanine-inhibited; phospho-2-keto-3-deoxyheptonate aldol\nase; 2-dehydro-3-deoxyphosphoheptonate aldolase; 3-deoxy-D-a\nrabine-heptulosonate-7-phosphate synthase,null mutant is via\nble\n mARO4:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase \nisoenzyme,3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP)\n synthase isoenzyme,null mutant is viable\n mAQR2:Unknown ,, Unknown\n Cond729:sin3\n mARO8:aromatic amino acid aminotransferase,aromatic amino acid ami\nnotransferase,Null mutant is viable\n mSDT1:suppressor of deletion of TFIIS,,null mutant is viable, but \nis sensitive to 6-azauracil\n mARO9:aromatic amino acid aminotransferase II,aromatic amino acid \naminotransferase II,Null mutant is viable\n Cond90:jnm1\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt.  Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond53:erg2\n mZTA1:Zeta-crystallin homolog, has similarity to E. coli quinone o\nxidoreductase and human zeta-crystallin which has quinone ox\nidoreductase activity,,\n mNCE103:involved in secretion of proteins that lack classical secret\nory signal sequences,,An uncharacterized allele exhibits def\nects in the export of the mammalian protein galectin-1.\n mYLR089C:Unknown ,, Unknown\n mYOL118C:Unknown ,, Unknown\n mAAT2:aspartate aminotransferase, cytosolic,aspartate aminotransfe\nrase,\n mYNR069C:Unknown ,, Unknown\n Cond6:anp1\n mSRY1:Serine Racemase homolog in Yeast,pyridoxal-5'phosphate-depen\ndent enzyme , similar to mouse glial serine racemase,Null mu\ntant is viable\n Cond635:DES460_+_0.02%_MMS_-_30_min\n Cond298:Terbinafine\n mYBR147W:Unknown ,, Unknown\n Cond78:hir2\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond85:imp2\n mNIT1:nitrilase,nitrilase,\n Cond201:yel008w\n mYPL264C:Unknown ,, Unknown\n Cond229:yhr011w(**14)\n mSER1:phosphoserine transaminase,phosphoserine transaminase,Null m\nutant is viable, serine-requiring\n mYHR029C:Unknown ,, Unknown\n mMET10:subunit of assimilatory sulfite reductase,assimilatory sulfi\nte reductase subunit,Null mutant is viable, and is a methion\nine auxotroph\n mSER3:catalyzes the first step in serine biosynthesis; isozyme of \nSER33,3-phosphoglycerate dehydrogenase,enzyme activity of 3P\n-glycerate dehydrogenase is decreased in null mutant compare\nd to wildtype and abolished in ser3 ser33 double deletion mu\ntant\n Cond176:swi5\n mAPG1:Required for autophagy,protein kinase,Defective in autophagy\n; loses viability more rapidly than wild type during nitroge\nn starvation; defective in vacuolar protein degradation duri\nng nitrogen starvation; defective in sporulation\n mECM40:ExtraCellular Mutant,acetylornithine acetyltransferase,A Tn3\n insertion into this gene causes hypersensitivity to the cel\nl surface polymer perturbing agent calcofluor white.\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond287:2-deoxy-D-glucose\n mMET13:putative methylenetetrahydrofolate reductase (mthfr),methyle\nnetetrahydrofolate reductase (mthfr) (putative),Null mutant \nis viable and shows methionine auxotrophy; double disruption\n of MET12 and MET13 (the two putative mthfr genes) also conf\ners methionine auxotrophy, but has no other known phenotype \nat this time.\n mATR1:aminotriazole resistance,very hydrophobic, has many membrane\n-spanning regions, several potential glycosylation sites, po\ntential ATP-binding site,Null mutant is viable, but is sensi\ntive to very low (5 mM) levels of aminotriazole and to 4-nit\nroquinoline-N-oxide (4-NQO); multiple copies of ATR1 confer \nhyper-resistance to 4-NQO; multiple copies of ATR1 in gcn4 b\nackground confer resistance to high (80mM) levels of aminotr\niazole\n Cond48:ecm29\n mMET16:3'phosphoadenylylsulfate reductase,3'phosphoadenylylsulfate \nreductase,Null mutant is viable, and is a methionine auxotro\nph\n Cond478:WT+/-10mM3AT(R491)\n Cond128:rgt1\n mMET17:O-Acetylhomoserine-O-Acetylserine Sulfhydralase,O-acetylhomo\nserine (thiol)-lyase,Null mutant is viable, methionine auxot\nroph, becomes darkly pigmented in the presence of Pb2+ ions;\n resistant to methylmercury and exhibits increased levels of\n H2S\n Cond144:rtg1\n Cond150:sbh2\n Cond47:ecm18(**7)\n mUGA3:Transcriptional activator necessary for gamma-aminobutyrate \n(GABA)-dependent induction of GABA genes (such as UGA1, UGA2\n, UGA4),zinc finger transcription factor of the Zn(2)-Cys(6)\n binuclear cluster domain type,Null mutant is viable but exh\nibits defects in activation of UGA1 and UGA4.\n mLEU4:leucine biosynthesis,alpha-isopropylmalate synthase (2-isopr\nopylmalate synthase),Null mutant is viable, Leu+\n Cond43:dot4\n mYIL165C:Unknown ,, Unknown\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond24:cem1\n mYDR426C:Unknown ,, Unknown\n Cond132:rnr1(haploid**9)\n mALD5:Utilizes NADP+ as the preferred coenzyme. Activated by K+.,a\nldehyde dehydrogenase,\n mPRM5:pheromone-regulated membrane protein,,\n mSNO1:SNZ1 proximal ORF, stationary phase induced gene,,Null mutan\nt is viable, sensitive to 6-azauracil and methylene blue.\n Cond171:ste24(haploid)\n mYHM1:high copy suppressor of abf2 lacking the HMG1-like mitochond\nrial HM protein; putative mitochondrial carrier protein,,Nul\nl mutant is viable; shm1 abf2 double deletion cannot grow on\n glycerol\n mASN1:Asn1p and Asn2p are isozymes,asparagine synthetase,Null muta\nnt is viable; L-asparagine auxotrophy occurs upon mutation o\nf both ASN1 and ASN2\n Cond175:swi4\n mYJR111C:Unknown ,, Unknown\n Cond250:ymr031w-a\n mPDX3:pyridoxine (pyridoxiamine) phosphate oxidase,pyridoxine (pyr\nidoxiamine) phosphate oxidase,\n mTMT1:Trans-aconitate Methyltransferase 1,,\n Cond284:PMA1(tetpromoter)\n mYIL056W:Unknown ,, Unknown\n Cond153:sgs1\n mBIO3:biotin biosynthesis,7,8-diamino-pelargonic acid aminotransfe\nrase (DAPA) aminotransferase,\n mYJR154W:Unknown ,, Unknown\n mBIO5:transmembrane regulator of KAPA/DAPA transport,transmembrane\n regulator of KAPA/DAPA transport,\n mPHO89:Probable Na+/Pi symporter,Na+/Pi symporter (putative),Null m\nutant is viable\n mMET22:Putative phosphatase gene involved in salt tolerance and met\nhionine biogenesis; halotolerance,3'(2')5'-bisphosphate nucl\neotidase,Methionine requiring; lacks 3'-phosphoadenylylsulfa\nte (PAPS) reductase activity; unable to grow on sulfate as s\nole sulfur source\n mPCL5:PHO85 cyclin,,Null mutant is viable.\n mISU1:Iron-sulfur cluster nifU-like protein,,Null mutant is viable\n on YPD at 30 degrees C, and is synthetically lethal with is\nu2 null.\n Cond294:Itraconazole\n mYPL033C:Unknown ,, Unknown\n Cond159:sir3\n Cond295:Lovastatin\n mYBR047W:Unknown ,, Unknown\n mBNA1:biosynthesis of nicotinic acid,3-hydroxyanthranilic acid dio\nxygenase,Null mutant is viable, nicotinic acid auxotroph\n Cond299:Tunicamycin\n Cond274:yor080w(**3)\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond938:2h\n Cond392:aa_starv_2_h\n mORT1:Mitochondrial integral membrane protein, ornithine transport\ner,,Null mutant is viable, arginine bradytroph\n mHIS1:involved in the first step of histidine biosynthesis,ATP pho\nsphoribosyltransferase,Null mutant is viable and requires hi\nstidine\n mTRP2 mTRP3 mCPA2 mCPA1 mSNO1 mSNZ1
Cond158:sir2\n Cond217:yer050c\n Cond277:AUR1(tetpromoter)\n Cond698:gal3-gal\n Cond476:GCN4C/GCN4(R4760/R6257)\n Cond221:yer083c\n Cond104:npr2\n Cond164:sst2(haploid)\n Cond95:mac1\n Cond13:ase1(**12)\n Cond648:dun1-_+_0.02%_MMS_-_90_min\n Cond730:hda1\n Cond697:gal2-gal\n Cond315:37C_to_25C_shock_-_15_min\n Cond12:arg80\n Cond244:ymr010w\n Cond637:DES460_+_0.02%_MMS_-_60_min\n Cond445:Msn4_overexpression\n Cond30:clb6\n Cond702:gal7-gal\n Cond391:aa_starv_1_h\n Cond517:sst2D/wtlog10(intensity)\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond393:aa_starv_4_h\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond966:swi1,_YPD_(a)\n Cond788:NaCl_60'\n Cond245:ymr014w\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond677:DES459_(mec1)_-_log_phase_(IR_time_=_0_sample)\n Cond184:ubr1\n Cond335:constant_0.32_mM_H2O2_(10_min)_redo\n Cond123:rad57\n Cond395:Nitrogen_Depletion_30_min.\n Cond279:ERG11(tetpromoter)\n Cond701:gal6-gal\n Cond247:ymr029c\n Cond689:gal3+gal\n Cond216:yer044c(haploid)\n Cond86:imp2'(**12)\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond693:gal7+gal\n Cond226:yhl029c\n Cond482:WT+/-100mM3AT(SetC)(KNY164)\n Cond194:yap1\n mTRP2:anthranilate synthase Component I,anthranilate synthase comp\nonent I,tryptophan requiring\n mTRP4:anthranilate phosphoribosyl transferase,anthranilate phospho\nribosyl transferase,tryptophan requiring\n Cond145:rts1\n Cond71:gln3\n Cond767:Acid_40'\n Cond481:WT+/-100mM3AT(SetB)(491)\n Cond54:erg3(haploid)\n Cond644:DES459_(mec1-)_+_0.02%_MMS_-_60_min\n Cond233:yhr039c\n Cond68:gas1\n Cond143:rrp6\n Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n Cond26:cka2\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Cond69:gcn4\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond108:pac2\n Cond205:yel033w\n Cond27:ckb2\n Cond394:aa_starv_6_h\n Cond731:hda1
\n Cond73:gyp1\n Cond691:gal5+gal\n Cond162:spf1\n Cond634:DES460_+_0.02%_MMS_-_15_min\n Cond230:yhr022c\n Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond25:cin5\n Cond742: Cond727:rpd3\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n  Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n Cond636:DES460_+_0.2%_MMS_-_45_min\n Cond643:DES459_(mec1-)_+_0.02%_MMS_-_45_min\n Cond39:dig1\n Cond160:sir4\n Cond135:rpl20a\n mCPA1:Carbamoyl phosphate synthetase, arginine specific,arginine s\npecific , carbamoyl phosphate synthetase,Null mutant is viab\nle\n mCPA2:carbamyl phosphate synthetase,carbamyl phosphate synthetase,\nNull mutant is viable\n Cond477:GCN4/gcn4Din100mM3AT(KNY164/KNY124)\n Cond664:mec1_plus_gamma_20_min\n Cond397:Nitrogen_Depletion_2_h\n Cond281:HMG2(tetpromoter)\n mARG1:arginosuccinate synthetase,arginosuccinate synthetase,Argini\nne requiring\n Cond316:37C_to_25C_shock_-_30_min\n mHOM2:threonine and methionine pathway,aspartic beta semi-aldehyde\n dehydrogenase,Homoserine requiring\n mARG3:Sixth step in arginine biosynthesis,ornithine carbamoyltrans\nferase,Arginine requiring\n Cond396:Nitrogen_Depletion_1_h\n Cond225:yhl013c\n mHOM3:First step in common pathway for methionine and threonine bi\nosynthesis,aspartate kinase (L-aspartate 4-P-transferase) (E\nC 2.7.2.4),Homoserine requiring; Borrelidin resistance\n mARG4:argininosuccinate lyase,argininosuccinate lyase,Arginine req\nuiring\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n mARG8:Acetylornithine aminotransferase,acetylornithine aminotransf\nerase,Arginine requiring\n Cond29:clb2\n Cond130:rml2(**13)\n Cond89:isw2\n Cond137:rpl34a(**9)\n mARG5,6:N-acetyl-gamma-glutamyl-phosphate reductase and acetylglutam\nate kinase,N-acetyl-gamma-glutamyl-phosphate reductase and a\ncetylglutamate kinase,Arginine requiring\n Cond224:CMD1(tetpromoter)\n Cond647:dun1-_+_0.02%_MMs_-_30_min\n Cond190:vps8\n Cond140:rps24a(**9)\n Cond729:sin3\n Cond15:bim1(**15)\n Cond745: Cond19:bub3(**2,8,13)\n Cond112:pep12\n Cond90:jnm1\n Cond967:swi1,_YPD_(c)\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt.  Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond53:erg2\n Y-Stre.Acid:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond940:6h\n Cond633:DES460_+_0.02%_MMS_-_5_min\n Cond937:t=0\n Cond6:anp1\n Cond635:DES460_+_0.02%_MMS_-_30_min\n Cond298:Terbinafine\n mYOR302W:Unknown ,, Unknown\n Cond78:hir2\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond201:yel008w\n Cond229:yhr011w(**14)\n Cond271:yor051c(**14)\n Cond176:swi5\n Cond345:1_mM_Menadione_(10_min)redo\n mECM40:ExtraCellular Mutant,acetylornithine acetyltransferase,A Tn3\n insertion into this gene causes hypersensitivity to the cel\nl surface polymer perturbing agent calcofluor white.\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond287:2-deoxy-D-glucose\n mMET13:putative methylenetetrahydrofolate reductase (mthfr),methyle\nnetetrahydrofolate reductase (mthfr) (putative),Null mutant \nis viable and shows methionine auxotrophy; double disruption\n of MET12 and MET13 (the two putative mthfr genes) also conf\ners methionine auxotrophy, but has no other known phenotype \nat this time.\n Cond222:yer084w\n Cond48:ecm29\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond478:WT+/-10mM3AT(R491)\n Cond128:rgt1\n Cond144:rtg1\n Cond150:sbh2\n SwiSnf.swisnf:Whole-genome expression analysis of snf/swi mutants of Sacch\naromyces cerevisiae.  Proc Natl Acad Sci U S A. 2000 Mar 28;\n97(7):3364-9.\n Cond47:ecm18(**7)\n Cond43:dot4\n Y-Stre.NaCl:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond63:fre6\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Cond24:cem1\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n  Science. 1998 Oct 23;282(5389):699-705.\n Cond132:rnr1(haploid**9)\n Cond642:DES459_(mec1-)_+_0.02%_MMS_-_30_min\n Cond171:ste24(haploid)\n Cond117:pfd2(**14)\n Stress.Menadione:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond175:swi4\n Cond250:ymr031w-a\n Cond284:PMA1(tetpromoter)\n Cond153:sgs1\n Cond349:1_mM_Menadione_(50_min)redo\n Cond398:Nitrogen_Depletion_4_h\n mMET22:Putative phosphatase gene involved in salt tolerance and met\nhionine biogenesis; halotolerance,3'(2')5'-bisphosphate nucl\neotidase,Methionine requiring; lacks 3'-phosphoadenylylsulfa\nte (PAPS) reductase activity; unable to grow on sulfate as s\nole sulfur source\n Cond682:MHY1_(crt1)_vs_CRY1_(wild_type)\n Cond294:Itraconazole\n Cond159:sir3\n Cond84:hst3\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond295:Lovastatin\n Cond348:1mM_Menadione_(40_min)_redo\n Cond968:swi1,_YPD_(d)\n Cond299:Tunicamycin\n Cond699:gal4-gal\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond938:2h\n Cond392:aa_starv_2_h\n mORT1:Mitochondrial integral membrane protein, ornithine transport\ner,,Null mutant is viable, arginine bradytroph\n Cond641:DES459_(mec1-)_+_0.02%_MMS_-_15_min\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n Cond665:mec1_plus_gamma_30_min\n Cond958:t0.5_g/r_ratio\n Cond703:gal10-gal\n mCPA2 mCPA1
Cond158:sir2\n mHIS4:histidinol dehydrogenase,histidinol dehydrogenase,Null mutan\nt is viable and requires histidine\n Cond277:AUR1(tetpromoter)\n mHIS5:responsive to control of general amino acid biosynthesis,his\ntidinol-phosphate aminotransferase,Null mutant is viable and\n requires histidine\n Cond476:GCN4C/GCN4(R4760/R6257)\n Cond698:gal3-gal\n mHIS7:glutamine amidotransferase:cyclase, also called imidazole gl\nycerol phosphate synthase,glutamine amidotransferase:cyclase\n , imidazole glycerol phosphate synthase (synonym),Null muta\nnt is viable and requires histidine\n Cond221:yer083c\n Cond164:sst2(haploid)\n Cond95:mac1\n Cond13:ase1(**12)\n mYOR203W:Unknown ,, Unknown\n Cond648:dun1-_+_0.02%_MMS_-_90_min\n Cond730:hda1\n Cond697:gal2-gal\n mMTD1:NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase,N\nAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase,Nu\nll mutant is viable, associated with loss of NAD-dependent 5\n,10-methylene-THF dehydrogenase activity and a purine requir\nement in some genetic backgrounds\n Cond352:1_mM_Menadione_(120_min)redo\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond315:37C_to_25C_shock_-_15_min\n Cond244:ymr010w\n Cond702:gal7-gal\n Cond696:gal1-gal\n Cond391:aa_starv_1_h\n Cond517:sst2D/wtlog10(intensity)\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond393:aa_starv_4_h\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond245:ymr014w\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond184:ubr1\n Cond123:rad57\n Cond395:Nitrogen_Depletion_30_min.\n Cond704:gal80-gal\n Cond279:ERG11(tetpromoter)\n Cond701:gal6-gal\n Cond689:gal3+gal\n Cond216:yer044c(haploid)\n Cond86:imp2'(**12)\n mSHM2:serine hydroxymethyltransferase,,Null mutant is viable\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond693:gal7+gal\n mLYS1:saccharopine dehydrogenase,,Lysine requiring\n Cond482:WT+/-100mM3AT(SetC)(KNY164)\n Cond226:yhl029c\n Cond694:gal10+gal\n mADE5,7:glycinamide ribotide synthetase and aminoimidazole ribotide \nsynthetase,aminoimidazole ribotide synthetase , glycinamide \nribotide synthetase,Adenine requiring\n mTRP3:anthranilate synthase Component II and indole-3-phosphate (m\nultifunctional enzyme),anthranilate synthase component II , \nindole-3-phosphate,Null mutant is viable, tryptophan auxotro\nph\n Cond700:gal5-gal\n Cond145:rts1\n Cond71:gln3\n Cond688:gal2+gal\n Cond481:WT+/-100mM3AT(SetB)(491)\n Cond54:erg3(haploid)\n Cond644:DES459_(mec1-)_+_0.02%_MMS_-_60_min\n mGCV2:Glycine CleaVage system,glycine cleavage system P subunit , \nglycine decarboxylase complex P subunit , glycine synthase P\n subunit,Inability to convert glycine to serine (ser1 backgr\nound); Inability to utilize glycine as a nitogen source.\n Cond116:pex12\n Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n Cond26:cka2\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Cond69:gcn4\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond205:yel033w\n Y-Stre.Alkali:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond687:gal1+gal\n Cond27:ckb2\n Cond731:hda1
\n Cond394:aa_starv_6_h\n Cond73:gyp1\n Cond691:gal5+gal\n Cond162:spf1\n mYER091C-A:Unknown ,, Unknown\n Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond25:cin5\n mMET6:vitamin B12-(cobalamin)-independent isozyme of methionine sy\nnthase (also called N5-methyltetrahydrofolate homocysteine m\nethyltransferase or 5-methyltetrahydropteroyl triglutamate h\nomocysteine methyltransferase),vitamin B12-(cobalamin)-indep\nendent isozyme of methionine synthase (also called N5-methyl\ntetrahydrofolate homocysteine methyltransferase or 5-methylt\netrahydropteroyl triglutamate homocysteine methyltransferase\n),Null mutant is viable, and is a methionine auxotroph\n Cond690:gal4+gal\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n  Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n Cond39:dig1\n Cond135:rpl20a\n mCPA2:carbamyl phosphate synthetase,carbamyl phosphate synthetase,\nNull mutant is viable\n Cond477:GCN4/gcn4Din100mM3AT(KNY164/KNY124)\n Cond397:Nitrogen_Depletion_2_h\n mARG1:arginosuccinate synthetase,arginosuccinate synthetase,Argini\nne requiring\n mHOM2:threonine and methionine pathway,aspartic beta semi-aldehyde\n dehydrogenase,Homoserine requiring\n Cond225:yhl013c\n mHOM3:First step in common pathway for methionine and threonine bi\nosynthesis,aspartate kinase (L-aspartate 4-P-transferase) (E\nC 2.7.2.4),Homoserine requiring; Borrelidin resistance\n Cond396:Nitrogen_Depletion_1_h\n mARG3:Sixth step in arginine biosynthesis,ornithine carbamoyltrans\nferase,Arginine requiring\n mARG4:argininosuccinate lyase,argininosuccinate lyase,Arginine req\nuiring\n mLYS20:homocitrate synthase, highly homologous to YDL131W,YDL131W (\nLYS21) homolog , homocitrate synthase,Null mutant is viable,\n is able to grow on minimal media, and exhibits reduced but \nsignificant homocitrate synthase activity\n Cond130:rml2(**13)\n Cond29:clb2\n mARG5,6:N-acetyl-gamma-glutamyl-phosphate reductase and acetylglutam\nate kinase,N-acetyl-gamma-glutamyl-phosphate reductase and a\ncetylglutamate kinase,Arginine requiring\n Cond647:dun1-_+_0.02%_MMs_-_30_min\n Cond190:vps8\n Cond2:ade2(haploid)\n Cond90:jnm1\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt.  Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond384:Hypo-osmotic_shock_-_5_min\n Cond53:erg2\n Cond772:Alkali_20'\n Cond6:anp1\n Cond298:Terbinafine\n Cond705:gal1gal10+gal\n Cond78:hir2\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond201:yel008w\n mSER1:phosphoserine transaminase,phosphoserine transaminase,Null m\nutant is viable, serine-requiring\n mSER2:phosphoserine phosphatase,phosphoserine phosphatase,serine-r\nequiring\n Cond176:swi5\n mSER3:catalyzes the first step in serine biosynthesis; isozyme of \nSER33,3-phosphoglycerate dehydrogenase,enzyme activity of 3P\n-glycerate dehydrogenase is decreased in null mutant compare\nd to wildtype and abolished in ser3 ser33 double deletion mu\ntant\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond287:2-deoxy-D-glucose\n mMET16:3'phosphoadenylylsulfate reductase,3'phosphoadenylylsulfate \nreductase,Null mutant is viable, and is a methionine auxotro\nph\n Cond128:rgt1\n Cond478:WT+/-10mM3AT(R491)\n Cond150:sbh2\n Cond144:rtg1\n Cond47:ecm18(**7)\n mUGA3:Transcriptional activator necessary for gamma-aminobutyrate \n(GABA)-dependent induction of GABA genes (such as UGA1, UGA2\n, UGA4),zinc finger transcription factor of the Zn(2)-Cys(6)\n binuclear cluster domain type,Null mutant is viable but exh\nibits defects in activation of UGA1 and UGA4.\n Cond43:dot4\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n mCEM1:homology with beta-keto-acyl synthases,beta-keto-acyl syntha\nse homolog,Null mutant is viable; exhibits respiratory-defic\nient growth\n Cond171:ste24(haploid)\n Cond83:hpt1\n Stress.Menadione:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mASN1:Asn1p and Asn2p are isozymes,asparagine synthetase,Null muta\nnt is viable; L-asparagine auxotrophy occurs upon mutation o\nf both ASN1 and ASN2\n mADE2:phosphoribosylamino-imidazole-carboxylase,phosphoribosylamin\no-imidazole-carboxylase,Null mutant is viable and requires a\ndenine. ade2 mutants are blocked at a stage in the adenine b\niosynthetic pathway that causes an intermediate to accumulat\ne in the vacuole; the intermediate gives the cell a red colo\nr.\n Cond175:swi4\n mADE3:Required for the biosynthesis of purines, thymidylate, methi\nonine, histidine, pantothenic acid and formylmethionyl-tRNA,\nC1-tetrahydrofolate synthase,Null mutant is viable, adenine \nauxotroph, histidine auxotroph\n mADE4:phosphoribosylpyrophosphate amidotransferase,phosphoribosylp\nyrophosphate amidotransferase,Adenine requiring\n Cond250:ymr031w-a\n mADE6:5'-phosphoribosylformyl glycinamidine synthetase,5'-phosphor\nibosylformyl glycinamidine synthetase,Adenine requiring\n Cond685:wt-gal\n mADE8:glycinamide ribotide transformylase,glycinamide ribotide tra\nnsformylase,Adenine requiring\n Cond398:Nitrogen_Depletion_4_h\n mMET22:Putative phosphatase gene involved in salt tolerance and met\nhionine biogenesis; halotolerance,3'(2')5'-bisphosphate nucl\neotidase,Methionine requiring; lacks 3'-phosphoadenylylsulfa\nte (PAPS) reductase activity; unable to grow on sulfate as s\nole sulfur source\n Cond707:gal4gal80-gal\n Cond294:Itraconazole\n Cond159:sir3\n Cond295:Lovastatin\n Cond299:Tunicamycin\n Cond699:gal4-gal\n mADE13:Adenylosuccinate Lyase,adenylosuccinate lyase,Unable to grow\n on complete media with glucose or fructose as a carbon sour\nce, but can grow with glycerol or ethanol\n Cond771:Alkali_10'\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond392:aa_starv_2_h\n Cond703:gal10-gal\n mHIS1:involved in the first step of histidine biosynthesis,ATP pho\nsphoribosyltransferase,Null mutant is viable and requires hi\nstidine\n
Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n mHIS3:imidazoleglycerol-phosphate dehydratase,imidazoleglycerol-ph\nosphate dehydratase,Null mutant is viable and requires histi\ndine\n Cond158:sir2\n Cond217:yer050c\n Cond277:AUR1(tetpromoter)\n Cond698:gal3-gal\n Cond476:GCN4C/GCN4(R4760/R6257)\n Cond221:yer083c\n mMCH1:Unknown ,, Unknown\n Cond95:mac1\n Cond13:ase1(**12)\n Cond950:TPK1_MT1val\n Cond648:dun1-_+_0.02%_MMS_-_90_min\n Cond730:hda1\n Cond244:ymr010w\n mOAC1:oxaloacetate carrier,oxaloacetate transport protein,\n Cond391:aa_starv_1_h\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond184:ubr1\n Cond123:rad57\n Cond395:Nitrogen_Depletion_30_min.\n Cond279:ERG11(tetpromoter)\n Cond701:gal6-gal\n Cond247:ymr029c\n Cond216:yer044c(haploid)\n Cond86:imp2'(**12)\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond693:gal7+gal\n Cond226:yhl029c\n Cond482:WT+/-100mM3AT(SetC)(KNY164)\n mADH5:alcohol dehydrogenase isoenzyme V,alcohol dehydrogenase isoe\nnzyme V,\n mTRP4:anthranilate phosphoribosyl transferase,anthranilate phospho\nribosyl transferase,tryptophan requiring\n Cond145:rts1\n Cond71:gln3\n Cond481:WT+/-100mM3AT(SetB)(491)\n Cond54:erg3(haploid)\n Cond293:HU\n Cond233:yhr039c\n mILV2:acetolactate synthase,acetolactate synthase,Isoleucine-plus-\nvaline requiring; Sulfometuron methyl resistance\n Cond68:gas1\n Cond949:WT1val\n mILV3:catalyzes third step in common pathway leading to biosynthes\nis of branched-chain amino acids,dihydroxyacid dehydratase,N\null mutant is viable and requires isoleucine and valine\n mBOP2:bypass of PAM1,,\n Cond143:rrp6\n Cond542:fus3Dtec1D+50nMaF,30min/wtlog10(intensity)\n Cond26:cka2\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Cond69:gcn4\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond27:ckb2\n Cond731:hda1
\n Cond73:gyp1\n Cond951:WT2val\n Cond691:gal5+gal\n Cond162:spf1\n Cond959:t2_g/r_ratio\n Cond634:DES460_+_0.02%_MMS_-_15_min\n Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n Cond25:cin5\n Cond21:bul1\n Cond952:TPK1_MT2val\n mYOR271C:Unknown ,, Unknown\n mYMC1:putative mitochondrial carrier protein,carrier protein (puta\ntive),\n mBAT1:branched-chain amino acid transaminase, highly similar to ma\nmmalian ECA39, which is regulated by the oncogene myc,branch\ned-chain amino acid transaminase , highly similar to mammali\nan ECA39, which is regulated by the oncogene myc , branched-\nchain amino acid transaminase , highly similar to mammalian \nECA39, which is regulated by the oncogene myc,Null mutant is\n viable; ILV auxotrophy in bat1 bat2 double mutant\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n  Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n Cond627:DY1457_(wild_type)_3_mM_vs._76_nM_zinc_y12-122\n Cond39:dig1\n Cond160:sir4\n Cond135:rpl20a\n mCPA2:carbamyl phosphate synthetase,carbamyl phosphate synthetase,\nNull mutant is viable\n Cond477:GCN4/gcn4Din100mM3AT(KNY164/KNY124)\n Cond397:Nitrogen_Depletion_2_h\n mARG1:arginosuccinate synthetase,arginosuccinate synthetase,Argini\nne requiring\n mHOM3:First step in common pathway for methionine and threonine bi\nosynthesis,aspartate kinase (L-aspartate 4-P-transferase) (E\nC 2.7.2.4),Homoserine requiring; Borrelidin resistance\n Cond260:ymr237w\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond130:rml2(**13)\n Cond29:clb2\n Cond89:isw2\n TPK.TPK:The yeast A kinases differentially regulate iron uptake and \nrespiratory function.  Proc Natl Acad Sci U S A. 2000 May 23\n;97(11):5984-8.\n mARG5,6:N-acetyl-gamma-glutamyl-phosphate reductase and acetylglutam\nate kinase,N-acetyl-gamma-glutamyl-phosphate reductase and a\ncetylglutamate kinase,Arginine requiring\n Cond647:dun1-_+_0.02%_MMs_-_30_min\n Cond190:vps8\n Cond99:med2(haploid)\n Cond140:rps24a(**9)\n Cond112:pep12\n Cond90:jnm1\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt.  Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond53:erg2\n Cond6:anp1\n Cond937:t=0\n Cond298:Terbinafine\n Cond78:hir2\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond201:yel008w\n Cond229:yhr011w(**14)\n Cond271:yor051c(**14)\n mAPG1:Required for autophagy,protein kinase,Defective in autophagy\n; loses viability more rapidly than wild type during nitroge\nn starvation; defective in vacuolar protein degradation duri\nng nitrogen starvation; defective in sporulation\n Cond176:swi5\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond287:2-deoxy-D-glucose\n mMET17:O-Acetylhomoserine-O-Acetylserine Sulfhydralase,O-acetylhomo\nserine (thiol)-lyase,Null mutant is viable, methionine auxot\nroph, becomes darkly pigmented in the presence of Pb2+ ions;\n resistant to methylmercury and exhibits increased levels of\n H2S\n Cond478:WT+/-10mM3AT(R491)\n mLEU1:leucine biosynthesis,isopropylmalate isomerase,Leucine requi\nring\n Cond150:sbh2\n Cond144:rtg1\n mLEU4:leucine biosynthesis,alpha-isopropylmalate synthase (2-isopr\nopylmalate synthase),Null mutant is viable, Leu+\n Cond63:fre6\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n  Science. 1998 Oct 23;282(5389):699-705.\n mALD5:Utilizes NADP+ as the preferred coenzyme. Activated by K+.,a\nldehyde dehydrogenase,\n Cond132:rnr1(haploid**9)\n Cond642:DES459_(mec1-)_+_0.02%_MMS_-_30_min\n mYHM1:high copy suppressor of abf2 lacking the HMG1-like mitochond\nrial HM protein; putative mitochondrial carrier protein,,Nul\nl mutant is viable; shm1 abf2 double deletion cannot grow on\n glycerol\n Cond171:ste24(haploid)\n Cond175:swi4\n Cond250:ymr031w-a\n Cond153:sgs1\n Cond398:Nitrogen_Depletion_4_h\n mBIO3:biotin biosynthesis,7,8-diamino-pelargonic acid aminotransfe\nrase (DAPA) aminotransferase,\n Cond294:Itraconazole\n mISU2:Iron-sulfur cluster nifU-like protein,,Null mutant is viable\n on YPD at 30 degrees C, and is synthetically lethal with is\nu1 null.\n Cond159:sir3\n mBAP2:contains 12 predicted transmembrane domains,amino acid perme\nase for leucine, valine, and isoleucine (putative),reduced u\nptake of leucine, isoleucine, and valine\n Cond295:Lovastatin\n Cond299:Tunicamycin\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast.  Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond274:yor080w(**3)\n Cond161:sod1(haploid)\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond392:aa_starv_2_h\n mYOR108W:Unknown ,, Unknown\n Cond953:TPK2_MT1val\n mHIS1:involved in the first step of histidine biosynthesis,ATP pho\nsphoribosyltransferase,Null mutant is viable and requires hi\nstidine\n Cond958:t0.5_g/r_ratio\n

this is an automaticly generated GENESYS report
Computational Genomics Lab, Tel-Aviv uniresity