Module G2/M_transition_of_mitotic_cell_cycle




Database revision : gnsdb28.10
Date : Fri Feb 28 01:36:31 2003
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Cond547:cln3-1\n Cond498:wtħ500nMaF,30minlog10(intensity)\n mMCD1:Mitotic Chromosome Determinant; similar to S. pombe RAD21; m\nay function in chromosome morphogenesis from S phase through\n mitosis,,Null mutant is inviable; temperature sensitive mut\nants are defective in mitotic sister chromatid cohesion and \nmitotic chromosome condensation; multicopy suppressor of smc\n1-2 mutation\n mTOS2:Hypothetical ORF,,\n mAXL2:involved in polarity establishment/cellular polarization dur\ning budding,,AXL2 can serve as a multicopy suppressor of rho\n3 and is required for the haploid axial budding pattern of S\n. cerevisiae.\n mTOS4:Hypothetical ORF,,\n Cond494:wtħ5nMaF,30minlog10(intensity)\n mTOS7:Hypothetical ORF,,\n Cond548:cln3-2\n Cond578:cdc15_130\n mASH1:Zinc-finger inhibitor of HO transcription which is asymmetri\ncally localized to the daughter cell nucleus,,Mutant ash1 da\nughters can transcribe HO and switch mating type\n Cond500:wtħ50nMaF,15minlog10(intensity)\n Cond751: mEGT2:cell-cycle regulation protein, may be involved in the correc\nt timing of cell separation after cytokinesis,,\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond585:cdc15_200\n Cond740: mYIL141W:Unknown ,, Unknown\n Cond224:CMD1(tetpromoter)\n mBUD9:among a group of genes whose products are necessary for bud-\nsite selection; likely involvement in positioning the proxim\nal pole signal,,In null mutants bipolar-budding cells bud pr\neferentially at distal pole\n Cond504:wtħ50nMaF,90minlog10(intensity)\n mCLB5:role in DNA replication during S phase; additional functiona\nl role in formation of mitotic spindles along with Clb3 and \nClb4,B-type cyclin,Null mutant is viable, but has an extende\nd S phase\n mYBR070C:Unknown ,, Unknown\n Cond579:cdc15_140\n mCLB6:role in DNA replication during S phase,B-type cyclin,Null mu\ntant is viable\n mNIS1:Hypothetical ORF,,\n Cond556:alpha35\n Cond561:alpha70\n mRFA1:Required for DNA-damage repair, full levels of gene conversi\non and sporulation,heterotrimeric RPA (RF-A) single-stranded\n DNA binding protein 69 kDa subunit; binds URS1 and CAR1,Nul\nl mutant is inviable; cells lacking RFA1 accumulate as multi\nply budded cells with a single nucleus suggesting a defect i\nn DNA replication; rfa1 repair defects are suppressed by hig\nh copy RAD52\n mYPL158C:Unknown ,, Unknown\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond573:cdc15_80\n mYLR049C:Unknown ,, Unknown\n Cond586:cdc15_210\n mPOL12:Required for DNA synthesis and correct progression through S\n phase; plays an essential role at early stage of chromosoma\nl DNA replication, before the hydroxyurea-sensitive step,DNA\n polymerase alpha-primase complex B subunit,Null mutant is i\nnviable\n mPST1:Protoplasts-secreted,the gene product has been detected amon\ng the proteins secreted by regenerating protoplasts,Viable\n Cond733: Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n mYLR194C:Unknown ,, Unknown\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n mHSP150:Heat shock protein, secretory glycoprotein,heat shock protei\nn , secretory glycoprotein , heat shock protein , secretory \nglycoprotein , heat shock protein , secretory glycoprotein,N\null mutant is viable\n Cond562:alpha77\n Cond496:wtħ50nMaF,30minlog10(intensity)\n mCLN1:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest\n mCLN2:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest; dominant mutation advances the G(sub)1- to\n S- phase transition and impairs ability of cells to arrest \nin G(sub)1 phase in response to external signals\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n mPMS1:Required for mismatch repair in mitosis and meiosis, low lev\nels of postmeiotic segregation, and high spore viability, di\nspensable for homeologous recombination,mutL homolog , simil\nar to Mlh1p, associates with Mlh1p, possibly forming a heter\nodimer, Pms1p and Msh1p act in concert to bind to a Msh2p-he\nteroduplex complex containing a G-T mismatch,Null mutant is \nviable; postmeiotic segregation increased\n mCRH1:congo red hypersensitive,cell wall protein,Null mutant is vi\nable and hypersensitive to Congo Red and Calcofluor White\n mYKR077W:Unknown ,, Unknown\n Cond753: mYCL022C:Unknown ,, Unknown\n mYPL267W:Unknown ,, Unknown\n mCSI2:chitin synthase involved,chitin synthase 3 complex structura\nl component (putative),Null mutant is viable but shows deloc\nalized chitin deposition\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n Cond553:alpha14\n Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n Cond749: mMSH2:Functions with Pms1p and Pms2/Mlh1p in a complex that intera\ncts with Pms3p/Msh6p to repair single-base and insertion-del\netion mispairs, or Msh3p to repair insertion-deletion mispai\nrs.,mutS homolog,Null mutant is viable. Haploid mutants disp\nlay an 85-fold increased rate of spontaneous mutation to can\navanine resistance. Mutants are defective for gene conversio\nn polarity gradients and high spore viability.\n Cond176:swi5\n Cond557:alpha42\n mMSH6:Required for mismatch repair in mitosis & meiosis, low level\ns of postmeiotic segregation & high spore viability; forms c\nomplex with Msh2p to repair both single-base & insertion-del\netion mispairs; redundant with Msh3p in repair of in-dels,hu\nman GTBP protein homolog,Null mutant is viable, msh3 msh6 do\nuble deletion mutants exhibit microsatellite instability and\n mutability similar to that in a msh2 mutant\n mYBR089W:Unknown ,, Unknown\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Cond580:cdc15_150\n mPRI2:p58 polypeptide of DNA primase,DNA primase p58 polypeptide,l\nethal\n mCHS1:disrupts mating and sporulation efficiently,chitin synthase \n1,Null mutant is viable\n mSIC1:P40 inhibitor of Cdc28p-Clb5 protein kinase complex,,Null mu\ntant is viable, shows increased frequency of broken and lost\n chromosomes; sic1 deletion mutant rescues lethality of cln1\n cln2 cln3 triple mutant.\n mYBR071W:Unknown ,, Unknown\n Cond502:wtħ50nMaF,45minlog10(intensity)\n Cond54:erg3(haploid)\n Cond581:cdc15_160\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond563:alpha84\n Cond558:alpha49\n Cond734: Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond582:cdc15_170\n Cond653:wt_plus_gamma_30_min\n Cond501:wt+/-50nMaF,30minlog10(intensity)\n mKCC4:involved in septin organization,S. pombe Nim1 homolog , prot\nein kinase,Null mutant is viable\n mPCL2:Interacts with cyclin-dependent kinase PHO85 to form kinase \ncomplex with G1-periodic activity involved in cell cycle pro\ngression,G1 cyclin,\n Cond554:alpha21\n Cond738:90\n mPOL30:Accessory factor for DNA polymerase delta, mRNA increases in\n G1, peaks in S in mitosis, & increases prior to DNA synthes\nis in meiosis; required for DNA replication & repair, requir\ned for viability in cdc44, rad50, rad52 or rad57 backgrounds\n,,Null mutant is inviable\n Cond571:cdc15_50\n Cond575:cdc15_100\n mRSR1:Gtp-binding protein of the ras superfamily involved in bud s\nite selection,,random budding pattern\n mPCL9:PHO85 cyclin,,Null mutant is viable.\n Cond574:cdc15_90\n Cond737: mCTS1:Endochitinase,endochitinase,Null mutant is viable; exhibits \na defect in cell separation\n Cond747: mSPT21:involved in trascriptional regulation of Ty1 LTRs,non-specif\nic DNA binding protein,Null mutant is viable, spt21 mutation\ns suppress Ty insertion mutations\n Cond497:wtħ158nMaF,30minlog10(intensity)\n Cond560:alpha63\n Cond576:cdc15_110\n mDSE3:Hypothetical ORF,,\n mDSE4:Hypothetical ORF,,\n Cond570:cdc15_30\n Cond736: Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Cond584:cdc15_190\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond559:alpha56\n mFAA3:acyl-CoA synthetase (long-chain fatty acid CoA ligase) (fatt\ny acid activator 3), activates endogenous but not imported f\natty acids and provides substrates for N-myristoylation,acyl\n-CoA synthase,Not essential for vegetative growth when fatty\n acid synthase (fas) is active\n Cond750: Cond567:alpha112\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n mPIR1:Protein containing tandem internal repeats,contains tandem i\nnternal repeats,Null mutant is viable; pir1 hsp150 (pir2) do\nuble mutant and pir1 hsp150 (pir2) pir3 triple mutant are sl\now-growing on agar slab and sensitive to heat shock\n Cond551:alpha0\n Cond549:clb2-2\n mYOX1:Homeodomain protein that binds leu-tRNA gene,homeobox-domain\n containing protein,Null mutant is viable\n mPIR3:Protein containing tandem internal repeats,contains tandem i\nnternal repeats,Null mutant is viable; pir1 hsp150 (pir2) pi\nr3 triple mutant is slow-growing on agar slab and sensitive \nto heat shock\n mMSH6 mPMS1 mMSH2 mSIC1 mCLB5
Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n Cond498:wtħ500nMaF,30minlog10(intensity)\n mHST3:Homolog of SIR2,,hst3 hst4 double mutant has defects in telo\nmeric silencing, cell cycle progression, radiation resistanc\ne, and genomic stability\n Cond281:HMG2(tetpromoter)\n Cond541:fus3D+50nMaF,30min/wtlog10(intensity)\n mSWI5:transcriptional activator,transcriptional activator,homothal\nlic switching deficient\n Cond221:yer083c\n Cond494:wtħ5nMaF,30minlog10(intensity)\n Cond798:Ca30'\n Cond548:cln3-2\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond418:YPD_1_d_ypd-2\n Cond13:ase1(**12)\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns.  J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond533:fus3D+50nMaF/wt+50nMaF,30minlog10(intensity)\n mCLB1:Involved in mitotic induction,B-type cyclin,Null mutant is v\niable (lethal in combination with clb2 mutation)\n Cond188:vma8\n mCLB2:Involved in mitotic induction,B-type cyclin,Null mutant is v\niable (lethal in combination with clb1 mutation)\n Cond504:wtħ50nMaF,90minlog10(intensity)\n mHOF1:SH3 domain containing-protein required for cytokinesis,,Null\n mutant is defective in cytokinesis\n mCLB6:role in DNA replication during S phase,B-type cyclin,Null mu\ntant is viable\n mMNN1:Alpha-1,3-mannosyltransferase,alpha-1,3-mannosyltransferase,\nNull mutant is viable\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond573:cdc15_80\n Cond519:rst1Drst2Dħ50nMaF,30minlog10(intensity)\n Cond505:wtħ50nMaF,120minlog10(intensity)\n Cond53:erg2\n mYDR134C:Unknown ,, Unknown\n Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n mGAS3:Unknown ,, Unknown\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n Cond916:(99i5)__HBY4_YPGL+G_NormInt\n Cond496:wtħ50nMaF,30minlog10(intensity)\n mCLN1:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond805:Ca/Ca+FK30'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n mHSN1:high copy suppressor of N34 dominant negative allele of SEC4\n; suppression very specific to this allele; no effect on the\n analogous YPT1 allele; no homology or known function,,Null \nmutant is viable and has no growth defects\n Cond566:alpha105\n mYPL267W:Unknown ,, Unknown\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n Cond279:ERG11(tetpromoter)\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYLR445W:Unknown ,, Unknown\n Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n mYHP1:Hypothetical ORF,,\n Cond216:yer044c(haploid)\n mWSC4:cell wall integrity and stress response component 4,contains\n novel cysteine motif , integral membrane protein (putative)\n , similar to SLG1 (WSC1), WSC2 and WSC3,\n mYBR187W:Unknown ,, Unknown\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond804:Ca/Ca+FK15'\n Cond333:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_15_minutes\n mBBP1:Involved in mitotic cell cycle and meiosis,,Null mutant is i\nnviable; cells depleted of Bbp1p are defective in nuclear se\ngregation, bud formation, cytokinesis and nuclear spindle fo\nrmation; overexpression gives ascus that contains asci inste\nad of spores\n Cond502:wtħ50nMaF,45minlog10(intensity)\n Cond54:erg3(haploid)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond68:gas1\n mRTT107:Establishes Silent Chromatin,,\n Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n Cond175:swi4\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYEL017W:Unknown ,, Unknown\n Cond653:wt_plus_gamma_30_min\n Cond501:wt+/-50nMaF,30minlog10(intensity)\n Cond250:ymr031w-a\n mHTA1:Histone H2A (HTA1 and HTA2 code for nearly identical protein\ns),histone H2A (HTA1 and HTA2 code for nearly identical prot\neins),Null mutant is viable\n mPOL30:Accessory factor for DNA polymerase delta, mRNA increases in\n G1, peaks in S in mitosis, & increases prior to DNA synthes\nis in meiosis; required for DNA replication & repair, requir\ned for viability in cdc44, rad50, rad52 or rad57 backgrounds\n,,Null mutant is inviable\n mHHF2:Histone H4 (HHF1 and HHF2 code for identical proteins),histo\nne H4 (HHF1 and HHF2 code for identical proteins),\n mYIL158W:Unknown ,, Unknown\n Cond294:Itraconazole\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond574:cdc15_90\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond497:wtħ158nMaF,30minlog10(intensity)\n mYNR009W:Unknown ,, Unknown\n Cond493:wtħ1.5nMaF,30minlog10(intensity)\n Cond299:Tunicamycin\n mSUR7:Multicopy suppressor of rvs167 mutation,integral membrane pr\notein (putative),Null mutant is viable, exhibits no growth d\nefects on non-fermentable carbon sources or sensitivites to \n3-AT or high salt\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast.  Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Cond503:wtħ50nMaF,60minlog10(intensity)\n mMEI5:Meiotic protein required for synapsis and meiotic recombinat\nion,,\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n mSRL1:Suppressor of rad53 lethality,,\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n Cond514:GAL-STE12,3hrs.gallog10(intensity)\n mYOR315W:Unknown ,, Unknown\n Cond551:alpha0\n Cond939:4h\n
Cond498:wtħ500nMaF,30minlog10(intensity)\n mHST3:Homolog of SIR2,,hst3 hst4 double mutant has defects in telo\nmeric silencing, cell cycle progression, radiation resistanc\ne, and genomic stability\n mMCD1:Mitotic Chromosome Determinant; similar to S. pombe RAD21; m\nay function in chromosome morphogenesis from S phase through\n mitosis,,Null mutant is inviable; temperature sensitive mut\nants are defective in mitotic sister chromatid cohesion and \nmitotic chromosome condensation; multicopy suppressor of smc\n1-2 mutation\n mSWI5:transcriptional activator,transcriptional activator,homothal\nlic switching deficient\n Cond494:wtħ5nMaF,30minlog10(intensity)\n Cond565:alpha98\n Cond548:cln3-2\n Cond552:alpha7\n mBUD4:co-assembles with Bud3p at bud sites,,Null mutant is viable,\n haploids have dipolar budding, normally they have axial bud\nding, no effects on diploids\n mYER079W:Unknown ,, Unknown\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond533:fus3D+50nMaF/wt+50nMaF,30minlog10(intensity)\n mCLB2:Involved in mitotic induction,B-type cyclin,Null mutant is v\niable (lethal in combination with clb1 mutation)\n mHHO1:Histone H1,histone H1,Null mutant is viable; other phenotype\n: Increased basal expression of a CYC1-lacz reporter gene; n\nuclear localization of a Hho1-GFP fusion protein\n Cond504:wtħ50nMaF,90minlog10(intensity)\n mHPR5:Required for proper timing of committment to meiotic recombi\nnation and the transition from Meiosis I to Meiosis II,DNA h\nelicase,Null mutant is viable, radiation (ultraviolet or ion\nizing sensitive), loss of function results in RAD52-dependen\nt hyperrecombination suggesting recombination suppression oc\ncurs by antagonizing the Rad52 recombinational repair pathwa\ny; wild-type suppresses mitotic recombination; some mutant a\nlleles have lower spore viability which is not rescued by sp\no13, suggesting they affect a late recombination function; h\npr5 mutations are rad6 suppressors\n mCLB6:role in DNA replication during S phase,B-type cyclin,Null mu\ntant is viable\n mMNN1:Alpha-1,3-mannosyltransferase,alpha-1,3-mannosyltransferase,\nNull mutant is viable\n mYJL051W:Unknown ,, Unknown\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond586:cdc15_210\n mCDC5:CDC5 is dispensable for premeiotic DNA synthesis and recombi\nnation, but required for tripartite synaptonemal complexes, \nhaploidization, and spores,protein kinase,Null mutant is inv\niable. cdc5(ts) mutants form synaptonemal complexes lacking \ncentral elements and arrest either at meiosis I with broken \nspindles or at meiosis II with short spindles. Late shifts t\no a restrictive temperature result in reductional dyads; eac\nh spore contains an entire meiosis II short spindle with uns\neparated chromatids. In some strains at semi-permissive temp\nerature, chromosomes segregate reductionally or equationally\n depending upon the centromere.\n Cond505:wtħ50nMaF,120minlog10(intensity)\n mGAS1:Glycophospholipid-anchored surface protein,cell surface glyc\noprotein 115-120 kDa,Null mutant is slow growing and exhibit\ns cell wall defects.\n Cond53:erg2\n Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n mNCE102:involved in secretion of proteins that lack classical secret\nory signal sequences,,An uncharacterized allele exhibits def\nects in the export of the mammalian protein galectin-1.\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n Cond496:wtħ50nMaF,30minlog10(intensity)\n mCLN1:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest\n mPPN1:Phosphate metabolism; transcription is regulated by PHO syst\nem,vacuolar polyphosphatase,Null mutant is viable and shows \naccumulation of long chain polyphosphate\n Cond805:Ca/Ca+FK30'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n mCIS3:cik1 suppressor,similar to Hsp150p and Pir1p, Pir2p, and Pir\n3p,Null mutant is viable; CIS3 is a high copy suppressor of \ncik1 deletion mutants\n mHTZ1:Histone-related protein that can suppress histone H4 point m\nutation,evolutionarily conserved member of the histone H2A F\n/Z family of histone variants,Null mutant is viable at 28C; \nhigh copy suppressor of histone H4 point mutant affecting nu\ncleosome structure\n mCWP1:cell wall protein, involved in O and N glycosylation, accept\nor of B1-6 glucan.,cell wall mannoprotein,Null mutant is via\nble, has increased sensitivities to calcoflour white and con\ngo red\n mYMR144W:Unknown ,, Unknown\n mYLR190W:Unknown ,, Unknown\n Cond566:alpha105\n mYPL267W:Unknown ,, Unknown\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n Cond279:ERG11(tetpromoter)\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond553:alpha14\n mPHO5:Acid phosphatase, repressible,acid phosphatase,phosphatase d\neficient\n Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n mYHP1:Hypothetical ORF,,\n mALK1:,leucine zipper (putative) , membrane protein (putative),\n Cond550:clb2-1\n mHHT1:Histone H3 (HHT1 and HHT2 code for identical proteins),histo\nne H3 (HHT1 and HHT2 code for identical proteins),Null mutan\nt is viable\n Cond557:alpha42\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Cond804:Ca/Ca+FK15'\n mYKL097C:Unknown ,, Unknown\n mCHS2:chitin synthase 2,chitin synthase 2,disruption results in lo\nss of well-defined septa and in growth arrest\n mYPL141C:Unknown ,, Unknown\n Cond502:wtħ50nMaF,45minlog10(intensity)\n Cond54:erg3(haploid)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond563:alpha84\n Cond558:alpha49\n mELO1:elongation enzyme 1, required for the elongation of the satu\nrated fatty acid tetradecanoic acid (14:0) to that of hexade\ncanoic acid (16:0),,Null mutant is viable, but shows no grow\nth on media supplemented with less than 16-C saturated fatty\n acid in a fatty acid synthase minus background\n mFIR1:Factor Interacting with REF2, interacts strongly with REF2 p\nrotein in 2-hybrid screen,participant in 3' mRNA processing \n(putative),Null mutant is viable, shows slow growth in all m\nedia\n Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n Cond175:swi4\n mMRH1:Membrane protein related to Hsp30p; Localized by immunofluor\nescence to membranes, mainly the plasma membr. punctuate imm\nunofluorescence pattern observed in buds. The nuclear envelo\npe, but not vacuole or mitochondrial membranes also stained,\n,Null mutant is viable\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYEL017W:Unknown ,, Unknown\n Cond501:wt+/-50nMaF,30minlog10(intensity)\n Cond250:ymr031w-a\n mHTA2:Histone H2A (HTA1 and HTA2 code for nearly identical protein\ns),histone H2A (HTA1 and HTA2 code for nearly identical prot\neins),Null mutant is viable. Deletion of the HTA2-HTB2 (TRT2\n) locus has no reported observable phenotypes, presumably be\ncause HTA1-HTB1 (TRT1) expression is upregulated and can com\npensate in the absence of TRT2. Overexpression of TRT2 can s\nuppress Ty insertion mutations\n Cond554:alpha21\n mSPC29:Nuclear import protein,spindle pole body associated protein,\nNull mutant is inviable\n mHEK2:Unknown ,, Unknown\n mCHA1:catabolism of hydroxy amino acids,catabolic serine (threonin\ne) dehydratase,Null mutant is viable and cannot grow on medi\na with L-serine or L-threonine as sole nitrogen source\n mYIL158W:Unknown ,, Unknown\n Cond294:Itraconazole\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n mTOS11:Hypothetical ORF,,\n mEXG1:Exo-1,3-beta-glucanase,exo-1,3-beta-glucanase,Null mutant is\n viable, displays modest increase in killer toxin sensitivit\ny and beta 1,6-glucan levels\n mEXG2:Exo-1,3-b-glucanase,exo-1,3-beta-glucanase,Null mutant is vi\nable\n Cond497:wtħ158nMaF,30minlog10(intensity)\n Cond576:cdc15_110\n Cond493:wtħ1.5nMaF,30minlog10(intensity)\n mYNR009W:Unknown ,, Unknown\n mYOR246C:Unknown ,, Unknown\n mSTU2:May play a role in attachment, organization, and/or dynamics\n of microtubule ends at the spindle pole body,,Null mutant i\ns inviable; stu2 mutations can suppress cold-sensitivity of \ntub2-423 mutants\n mSVS1:involved in vanadate resistance,,Null mutant is viable, show\ns increased sensitivity to vanadate, but not other metallic \nions or drugs\n mACE2:involved in transcriptional regulation of CUP1,zinc finger t\nranscription factor,Null mutant is viable, exhibits decrease\nd CUP1 mRNA expression\n Cond503:wtħ50nMaF,60minlog10(intensity)\n Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond559:alpha56\n mYRO2:Homolog to HSP30 heat shock protein Yro1p,,\n mSRL1:Suppressor of rad53 lethality,,\n mSWE1:protein kinase homolog,protein kinase homolog,Null mutant is\n viable\n Cond514:GAL-STE12,3hrs.gallog10(intensity)\n Cond567:alpha112\n mYOR315W:Unknown ,, Unknown\n mHTB1:Histone H2B (HTB1 and HTB2 code for nearly identical protein\ns),histone H2B (HTB1 and HTB2 code for nearly identical prot\neins),Null mutant is viable\n Cond551:alpha0\n Cond549:clb2-2\n mHTB2:Histone H2B (HTB1 and HTB2 code for nearly identical protein\ns),histone H2B (HTB1 and HTB2 code for nearly identical prot\neins),Null mutant is viable. Deletion of the HTA2-HTB2 (TRT2\n) locus has no reported observable phenotypes, presumably be\ncause HTA1-HTB1 (TRT1) expression is upregulated and can com\npensate in the absence of TRT2\n mYOX1:Homeodomain protein that binds leu-tRNA gene,homeobox-domain\n containing protein,Null mutant is viable\n mMCD1 mCDC5 mSWE1 mCLB2

this is an automaticly generated GENESYS report
Computational Genomics Lab, Tel-Aviv uniresity