Module DNA_replication_and_chromosome_cycle




Database revision : gnsdb28.10
Date : Fri Feb 28 01:36:32 2003
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Cond547:cln3-1\n Cond498:wtħ500nMaF,30minlog10(intensity)\n mMCD1:Mitotic Chromosome Determinant; similar to S. pombe RAD21; m\nay function in chromosome morphogenesis from S phase through\n mitosis,,Null mutant is inviable; temperature sensitive mut\nants are defective in mitotic sister chromatid cohesion and \nmitotic chromosome condensation; multicopy suppressor of smc\n1-2 mutation\n Cond541:fus3D+50nMaF,30min/wtlog10(intensity)\n mTOS4:Hypothetical ORF,,\n Cond494:wtħ5nMaF,30minlog10(intensity)\n Cond548:cln3-2\n Cond500:wtħ50nMaF,15minlog10(intensity)\n Cond751: Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n mYIL141W:Unknown ,, Unknown\n Cond504:wtħ50nMaF,90minlog10(intensity)\n Cond579:cdc15_140\n mCLB6:role in DNA replication during S phase,B-type cyclin,Null mu\ntant is viable\n mMIF2:centromere protein required for normal chromosome segregatio\nn and spindle integrity,,Null mutant is inviable, temperatur\ne sensitive mutants accumulate large budded cells and broken\n spindles at the restricitive temperature\n mRFA2:Involved in nucleotide excision repair,29% identical to the \nhuman p34 subunit of RF-A , replication factor RF-A subunit \n2,Null mutant is inviable; arrests as budded and multiply bu\ndded cells; rfa2 (ts) cells have a mutator and a hyper-recom\nbination phenotype and are more sensitive to hydroxyurea and\n methyl-methane-sulfonate than wild-type cells\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond519:rst1Drst2Dħ50nMaF,30minlog10(intensity)\n Cond669:mec1_plus_gamma_120_min\n Cond586:cdc15_210\n mPOL12:Required for DNA synthesis and correct progression through S\n phase; plays an essential role at early stage of chromosoma\nl DNA replication, before the hydroxyurea-sensitive step,DNA\n polymerase alpha-primase complex B subunit,Null mutant is i\nnviable\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt.  Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond733: Y-Stre.Acid:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n Cond562:alpha77\n Cond496:wtħ50nMaF,30minlog10(intensity)\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Cond568:alpha119\n Cond753: mYPL267W:Unknown ,, Unknown\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n Cond279:ERG11(tetpromoter)\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond553:alpha14\n Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n mMSH2:Functions with Pms1p and Pms2/Mlh1p in a complex that intera\ncts with Pms3p/Msh6p to repair single-base and insertion-del\netion mispairs, or Msh3p to repair insertion-deletion mispai\nrs.,mutS homolog,Null mutant is viable. Haploid mutants disp\nlay an 85-fold increased rate of spontaneous mutation to can\navanine resistance. Mutants are defective for gene conversio\nn polarity gradients and high spore viability.\n Cond216:yer044c(haploid)\n Cond550:clb2-1\n Cond557:alpha42\n Cond226:yhl029c\n mYBR089W:Unknown ,, Unknown\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Cond580:cdc15_150\n Cond65:fus3(haploid)\n mBUB1:checkpoint gene involved in permitting entry into mitosis de\npending upon the assembly state of microtubules,,Mutants are\n unable to recover from transient loss of spindle function. \nOverexpression of BUB1 rescues the cold sensitivity of tub1-\n729.\n mERP3:Emp24p/Erv25p related protein 2,p24 protein involved in memb\nrane trafficking,viable\n Cond767:Acid_40'\n mYBR071W:Unknown ,, Unknown\n Cond502:wtħ50nMaF,45minlog10(intensity)\n Cond581:cdc15_160\n Cond54:erg3(haploid)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond563:alpha84\n Cond558:alpha49\n Cond734: SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond746: Cond501:wt+/-50nMaF,30minlog10(intensity)\n Cond582:cdc15_170\n Cond98:mbp1\n Cond554:alpha21\n mHCM1:Dosage-dependent suppressor of cmd1-1 mutation; shows homolo\ngy to fork head family of DNA-binding proteins,,Null mutant \nis viable; exacerbates temperature-sensitivity of a cmd1-1 (\ncalmodulin) mutant\n mRAD51:Involved in processing ds breaks, synaptonemal complex forma\ntion, meiotic gene conversion and reciprocal recombination.,\nRad51p colocalizes to ~ 65 spots with Dmc1p prior to synapsi\ns (independently of ZIP1 and DMC1), and interacts with Rad52\np and Rad55p; human Rad51p homolog interacts with Brca2 prot\nein which has been implicated in causing breast cancer , Rec\nA homolog,Null mutant is viable; accumulates meiosis-specifi\nc double strand breaks at a recombination hotspot and reduce\ns the formation of physical recombinants and processed doubl\ne strand breaks with long heterogeneous tails; rad51 mutants\n are also defective for X-ray damage repair and gene convers\nions; rad51 rad27 mutants are inviable.\n Cond738:90\n Cond571:cdc15_50\n Cond575:cdc15_100\n Cond294:Itraconazole\n Cond574:cdc15_90\n Cond737: Cond538:fus3D/wtlog10(intensity)\n Cond747: mSPT21:involved in trascriptional regulation of Ty1 LTRs,non-specif\nic DNA binding protein,Null mutant is viable, spt21 mutation\ns suppress Ty insertion mutations\n Cond497:wtħ158nMaF,30minlog10(intensity)\n Cond576:cdc15_110\n Cond555:alpha28\n Cond493:wtħ1.5nMaF,30minlog10(intensity)\n Cond299:Tunicamycin\n Cond570:cdc15_30\n mRNR1:ribonucleotide reductase,ribonucleotide reductase, large (R1\n) subunit,Null mutant is inviable\n Cond736: Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond473:WT+/-MMS(DBY747)\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond559:alpha56\n mDNA2:DNA replication helicase,DNA replication helicase,Null mutan\nt is inviable\n Cond750: Cond510:fus3Dħ50nMaF,30minlog10(intensity)\n Cond567:alpha112\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n Cond551:alpha0\n Cond549:clb2-2\n
Cond547:cln3-1\n Cond498:wtħ500nMaF,30minlog10(intensity)\n Cond221:yer083c\n Cond494:wtħ5nMaF,30minlog10(intensity)\n Cond548:cln3-2\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond29:clb2\n Cond500:wtħ50nMaF,15minlog10(intensity)\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond941:SK1_YPD\n Cond735: Cond647:dun1-_+_0.02%_MMs_-_30_min\n Cond504:wtħ50nMaF,90minlog10(intensity)\n Y-Stre.msn2/4acid:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n mRFA1:Required for DNA-damage repair, full levels of gene conversi\non and sporulation,heterotrimeric RPA (RF-A) single-stranded\n DNA binding protein 69 kDa subunit; binds URS1 and CAR1,Nul\nl mutant is inviable; cells lacking RFA1 accumulate as multi\nply budded cells with a single nucleus suggesting a defect i\nn DNA replication; rfa1 repair defects are suppressed by hig\nh copy RAD52\n mRFA2:Involved in nucleotide excision repair,29% identical to the \nhuman p34 subunit of RF-A , replication factor RF-A subunit \n2,Null mutant is inviable; arrests as budded and multiply bu\ndded cells; rfa2 (ts) cells have a mutator and a hyper-recom\nbination phenotype and are more sensitive to hydroxyurea and\n methyl-methane-sulfonate than wild-type cells\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond15:bim1(**15)\n Cond519:rst1Drst2Dħ50nMaF,30minlog10(intensity)\n Cond669:mec1_plus_gamma_120_min\n Cond505:wtħ50nMaF,120minlog10(intensity)\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt.  Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond656:wt_plus_gamma_90_min\n Cond53:erg2\n Cond733: Cond940:6h\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n Cond562:alpha77\n Cond496:wtħ50nMaF,30minlog10(intensity)\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n mJEM1:DnaJ-like protein of the endoplasmic reticulum membrane,,Nul\nl mutant is viable but has karyogamy defect; jem1 scj1 doubl\ne mutant is temperature sensitive\n Cond948:W303_ume6_YPA_\n mYMR144W:Unknown ,, Unknown\n Cond6:anp1\n Cond934:8h\n Cond566:alpha105\n mPDS5:Precocious Dissociation of Sister chromatids,,\n Cond920:3h\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n Cond279:ERG11(tetpromoter)\n Cond961:t7_g/r_ratio\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond553:alpha14\n Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n Cond229:yhr011w(**14)\n Cond550:clb2-1\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond482:WT+/-100mM3AT(SetC)(KNY164)\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Cond287:2-deoxy-D-glucose\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond65:fus3(haploid)\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast.  Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond762:Heat_45'\n SwiSnf.swisnf:Whole-genome expression analysis of snf/swi mutants of Sacch\naromyces cerevisiae.  Proc Natl Acad Sci U S A. 2000 Mar 28;\n97(7):3364-9.\n Cond313:Heat_Shock_030inutes__hs-2\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond563:alpha84\n Cond558:alpha49\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n  Science. 1998 Oct 23;282(5389):699-705.\n mSEN34:tRNA splicing endonuclease 34kDa subunit; homologous to the \n42-kDa subunit, SEN2; contains active site for 3' splice sit\ne cleavage,tetrameric tRNA splicing endonuclease 34 kDa subu\nnit,Null mutant is inviable and shows H242A impaired 3'splic\ne site cleavage\n Cond68:gas1\n Cond734: Cond946:W303ume6_YPD\n Cond945:W303_YPD\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mSMC3:involved in sister chromatid cohesion,SMC chromosomal ATPase\n family member,Null mutant is inviable\n Cond746: Cond501:wt+/-50nMaF,30minlog10(intensity)\n Cond98:mbp1\n Cond687:gal1+gal\n Cond554:alpha21\n Cond738:90\n Cond483:Low-Pi_vs_High-Pi_in_WT_(NBW7)_exp1\n Cond959:t2_g/r_ratio\n Cond571:cdc15_50\n Cond743: Cond778:msn2/4_acid_10'\n Cond294:Itraconazole\n pho.Pho:New components of a system for phosphate accumulation and po\nlyphosphate metabolism in Saccharomyces cerevisiae revealed \nby genomic expression analysis.  Mol Biol Cell. 2000 Dec;11(\n12):4309-21.\n Cond969:swi1,_minimal_(a)\n Cond334:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_30_minutes\n Cond965:ndt80_delete_mid_g/r_ratio_\n Cond737: Cond747: Cond497:wtħ158nMaF,30minlog10(intensity)\n Cond555:alpha28\n Cond299:Tunicamycin\n Cond636:DES460_+_0.2%_MMS_-_45_min\n Cond960:t5_g/r_ratio\n Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Cond503:wtħ50nMaF,60minlog10(intensity)\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond559:alpha56\n Cond750: Cond510:fus3Dħ50nMaF,30minlog10(intensity)\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n Cond551:alpha0\n Cond549:clb2-2\n Cond939:4h\n mRFA1 mRFA2
mRAD27:DNA repair protein that belongs to the RAD2(pombe)/FEN1 subf\namily,42 kDa 5' to 3' exonuclease required for Okazaki fragm\nent processing,Null mutant is viable, demonstrates temperatu\nre-sensitive growth and sensitivity to UV light and to methy\nlmethane sulfonate\n Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n Cond498:wtħ500nMaF,30minlog10(intensity)\n Cond541:fus3D+50nMaF,30min/wtlog10(intensity)\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes.  Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond221:yer083c\n Cond494:wtħ5nMaF,30minlog10(intensity)\n Cond548:cln3-2\n Cond751: Cond13:ase1(**12)\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns.  J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond533:fus3D+50nMaF/wt+50nMaF,30minlog10(intensity)\n Cond579:cdc15_140\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond883:5\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond505:wtħ50nMaF,120minlog10(intensity)\n mGAS3:Unknown ,, Unknown\n Cond916:(99i5)__HBY4_YPGL+G_NormInt\n Cond562:alpha77\n Cond805:Ca/Ca+FK30'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond568:alpha119\n mYPL267W:Unknown ,, Unknown\n Cond279:ERG11(tetpromoter)\n Cond553:alpha14\n Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n Cond216:yer044c(haploid)\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond482:WT+/-100mM3AT(SetC)(KNY164)\n Cond580:cdc15_150\n Cond804:Ca/Ca+FK15'\n Cond65:fus3(haploid)\n Cond797:Ca15'\n Cond767:Acid_40'\n mBBP1:Involved in mitotic cell cycle and meiosis,,Null mutant is i\nnviable; cells depleted of Bbp1p are defective in nuclear se\ngregation, bud formation, cytokinesis and nuclear spindle fo\nrmation; overexpression gives ascus that contains asci inste\nad of spores\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond54:erg3(haploid)\n Cond581:cdc15_160\n Cond692:gal6+gal\n Cond558:alpha49\n Cond68:gas1\n Cond734: Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Cond945:W303_YPD\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond746: Cond819:crz1/Na45'_\n Cond582:cdc15_170\n Cond314:Heat_Shock_060_minutes__hs-2\n Y-Stre.Alkali:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond706:gal2gal80-gal\n Cond571:cdc15_50\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond965:ndt80_delete_mid_g/r_ratio_\n Cond737: Cond555:alpha28\n mYNR009W:Unknown ,, Unknown\n Cond493:wtħ1.5nMaF,30minlog10(intensity)\n Cond570:cdc15_30\n Cond960:t5_g/r_ratio\n mRNR1:ribonucleotide reductase,ribonucleotide reductase, large (R1\n) subunit,Null mutant is inviable\n Cond503:wtħ50nMaF,60minlog10(intensity)\n Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n Cond750: Cond510:fus3Dħ50nMaF,30minlog10(intensity)\n Cond567:alpha112\n Cond40:dig1,dig2\n Cond547:cln3-1\n mMCD1:Mitotic Chromosome Determinant; similar to S. pombe RAD21; m\nay function in chromosome morphogenesis from S phase through\n mitosis,,Null mutant is inviable; temperature sensitive mut\nants are defective in mitotic sister chromatid cohesion and \nmitotic chromosome condensation; multicopy suppressor of smc\n1-2 mutation\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond500:wtħ50nMaF,15minlog10(intensity)\n Cond504:wtħ50nMaF,90minlog10(intensity)\n Cond770:Acid_100'\n Cond519:rst1Drst2Dħ50nMaF,30minlog10(intensity)\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt.  Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond384:Hypo-osmotic_shock_-_5_min\n Cond53:erg2\n Y-Stre.Acid:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond733: Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n Cond496:wtħ50nMaF,30minlog10(intensity)\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond893:SMMS\n Cond768:Acid_60'\n Cond379:1M_sorbitol_-_30_min\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Cond287:2-deoxy-D-glucose\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast.  Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond502:wtħ50nMaF,45minlog10(intensity)\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Cond563:alpha84\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n  Science. 1998 Oct 23;282(5389):699-705.\n mCDC21:cell division cycle blocked at 36 degree C,thymidylate synth\nase,defective in continued replication during S phase of the\n cell cycle; temperature-sensitive thymidylate auxotroph\n Stress.Menadione:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond175:swi4\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond250:ymr031w-a\n Cond501:wt+/-50nMaF,30minlog10(intensity)\n Cond98:mbp1\n Cond554:alpha21\n Cond738:90\n Cond398:Nitrogen_Depletion_4_h\n Calcin.crz1Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond743: Cond776:Alkali_100'\n Cond294:Itraconazole\n mDUN1:DNA damage response,protein kinase,Null mutant is viable, de\nfective in DNA damage repair and in DNA damage-resposive ind\nuction of RNR genes, and sensitive to DNA damaging agents\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mSPT21:involved in trascriptional regulation of Ty1 LTRs,non-specif\nic DNA binding protein,Null mutant is viable, spt21 mutation\ns suppress Ty insertion mutations\n Cond747: Cond538:fus3D/wtlog10(intensity)\n Cond348:1mM_Menadione_(40_min)_redo\n mUFE1:t-SNARE that resides on the endoplasmic reticulum and mediat\nes retrograde traffic from the Golgi complex,t-SNARE (ER),Nu\nll mutant is inviable\n Cond497:wtħ158nMaF,30minlog10(intensity)\n mHSL1:Negative regulator of swe1 kinase (which regulates cdc28),pr\notein kinase  (putative) , similar to S. pombe cdr1/nim1,Nul\nl mutant is viable; synthetically lethal with histone H3 mut\nations; G2 delay\n Cond560:alpha63\n Cond299:Tunicamycin\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast.  Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond736: Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond559:alpha56\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n Cond551:alpha0\n Cond549:clb2-2\n Cond939:4h\n mYOX1:Homeodomain protein that binds leu-tRNA gene,homeobox-domain\n containing protein,Null mutant is viable\n
Cond547:cln3-1\n Cond330:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_15_minutes\n Cond498:wtħ500nMaF,30minlog10(intensity)\n Cond541:fus3D+50nMaF,30min/wtlog10(intensity)\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes.  Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond494:wtħ5nMaF,30minlog10(intensity)\n Cond548:cln3-2\n Cond649:dun1-_+_0.02%_MMS_-_120_min\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond500:wtħ50nMaF,15minlog10(intensity)\n Cond654:wt_plus_gamma_45_min\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond533:fus3D+50nMaF/wt+50nMaF,30minlog10(intensity)\n Cond648:dun1-_+_0.02%_MMS_-_90_min\n Cond647:dun1-_+_0.02%_MMs_-_30_min\n Cond504:wtħ50nMaF,90minlog10(intensity)\n Cond657:wt_plus_gamma_120_min\n Cond579:cdc15_140\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRFA2:Involved in nucleotide excision repair,29% identical to the \nhuman p34 subunit of RF-A , replication factor RF-A subunit \n2,Null mutant is inviable; arrests as budded and multiply bu\ndded cells; rfa2 (ts) cells have a mutator and a hyper-recom\nbination phenotype and are more sensitive to hydroxyurea and\n methyl-methane-sulfonate than wild-type cells\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond519:rst1Drst2Dħ50nMaF,30minlog10(intensity)\n Cond637:DES460_+_0.02%_MMS_-_60_min\n Cond822:tlc1_Expt.1_Passage_3\n Cond384:Hypo-osmotic_shock_-_5_min\n Cond656:wt_plus_gamma_90_min\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt.  Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond733: Cond651:wt_plus_gamma_10_min\n Cond940:6h\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n Cond562:alpha77\n Cond496:wtħ50nMaF,30minlog10(intensity)\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond805:Ca/Ca+FK30'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Cond231:yhr031c\n Cond638:DES460_+_0.02%_MMS_-_90_min\n Cond568:alpha119\n mYMR144W:Unknown ,, Unknown\n Cond937:t=0\n Cond635:DES460_+_0.02%_MMS_-_30_min\n mYPL267W:Unknown ,, Unknown\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n Cond279:ERG11(tetpromoter)\n Cond341:constant_0.32_mM_H2O2_(80_min)_redo\n Cond961:t7_g/r_ratio\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond553:alpha14\n Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n Cond646:DES459_(mec1-)_+_0.02%_MMS_-_120_min\n Cond226:yhl029c\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond65:fus3(haploid)\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae.  Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n Cond825:tlc1_Expt.1_Passage_6\n mDIN7:DNA-damage inducible gene,,\n Cond333:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_15_minutes\n Cond502:wtħ50nMaF,45minlog10(intensity)\n Cond54:erg3(haploid)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond563:alpha84\n Cond644:DES459_(mec1-)_+_0.02%_MMS_-_60_min\n Cond558:alpha49\n Cond877:MMS\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n  Science. 1998 Oct 23;282(5389):699-705.\n Cond293:HU\n Cond68:gas1\n Cond734: gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Cond175:swi4\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mSMC3:involved in sister chromatid cohesion,SMC chromosomal ATPase\n family member,Null mutant is inviable\n Cond819:crz1/Na45'_\n Cond746: Cond653:wt_plus_gamma_30_min\n Cond501:wt+/-50nMaF,30minlog10(intensity)\n Cond98:mbp1\n Cond554:alpha21\n mRAD51:Involved in processing ds breaks, synaptonemal complex forma\ntion, meiotic gene conversion and reciprocal recombination.,\nRad51p colocalizes to ~ 65 spots with Dmc1p prior to synapsi\ns (independently of ZIP1 and DMC1), and interacts with Rad52\np and Rad55p; human Rad51p homolog interacts with Brca2 prot\nein which has been implicated in causing breast cancer , Rec\nA homolog,Null mutant is viable; accumulates meiosis-specifi\nc double strand breaks at a recombination hotspot and reduce\ns the formation of physical recombinants and processed doubl\ne strand breaks with long heterogeneous tails; rad51 mutants\n are also defective for X-ray damage repair and gene convers\nions; rad51 rad27 mutants are inviable.\n Cond738:90\n Calcin.crz1Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond959:t2_g/r_ratio\n Cond571:cdc15_50\n Cond634:DES460_+_0.02%_MMS_-_15_min\n Cond743: Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n Cond707:gal4gal80-gal\n Cond294:Itraconazole\n Cond446:YAP1_overexpression\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond965:ndt80_delete_mid_g/r_ratio_\n mDUN1:DNA damage response,protein kinase,Null mutant is viable, de\nfective in DNA damage repair and in DNA damage-resposive ind\nuction of RNR genes, and sensitive to DNA damaging agents\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond206:yel044w\n Cond737: Cond538:fus3D/wtlog10(intensity)\n Cond747: Cond497:wtħ158nMaF,30minlog10(intensity)\n Cond560:alpha63\n Cond555:alpha28\n Cond493:wtħ1.5nMaF,30minlog10(intensity)\n Cond299:Tunicamycin\n Cond960:t5_g/r_ratio\n Cond636:DES460_+_0.2%_MMS_-_45_min\n mRNR1:ribonucleotide reductase,ribonucleotide reductase, large (R1\n) subunit,Null mutant is inviable\n Cond639:DES460_+_0.02%_MMS_-_120_min\n Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Cond503:wtħ50nMaF,60minlog10(intensity)\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond559:alpha56\n Cond750: Cond510:fus3Dħ50nMaF,30minlog10(intensity)\n mPLM2:Plasmid Maintenance,,Null mutant is viable and shows 2mu-m p\nlasmid instability\n Cond567:alpha112\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n Cond551:alpha0\n Cond652:wt_plus_gamma_20_min\n

this is an automaticly generated GENESYS report
Computational Genomics Lab, Tel-Aviv uniresity