| ID | Symbol | Description | Aliases | Front Node |
| YLR453C | RIF2 | Protein that binds to the Rap1p C-terminus and acts synergistically with Rif1p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation | | F |
| YPR060C | ARO7 | Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis | HGS1, OSM2, TYR7 | T |
| YJR097W | JJJ3 | Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein | DPH4 | T |
| YKR025W | RPC37 | RNA polymerase III subunit C37 | C37 | T |
| YPL010W | RET3 | Zeta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER | | T |
| YML123C | PHO84 | High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p | | T |
| YOR224C | RPB8 | RNA polymerase subunit ABC14.5, common to RNA polymerases I, II, and III | ABC14.5 | T |
| YPL160W | CDC60 | Cytosolic leucyl tRNA synthetase, ligates leucine to the appropriate tRNA | LeuRS | T |
| YDR216W | ADR1 | Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization | | F |
| YGR123C | PPT1 | Protein serine/threonine phosphatase with similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth | | T |
| YNL142W | MEP2 | Ammonium permease involved in regulation of pseudohyphal growth; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation | | T |
| YMR301C | ATM1 | Mitochondrial inner membrane transporter, exports mitochondrially synthesized precursors of iron-sulfur (Fe/S) clusters to the cytosol; member of the ATP-binding cassette (ABC) transporter family | | T |
| YNL186W | UBP10 | Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p and possibly other transporters; primarily located in the nucleus | DOT4 | T |
| YHR215W | PHO12 | One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway; nearly identical to Pho11p; upregulated by phosphate starvation | PHO10 | T |
| YLR272C | YCS4 | Non-SMC subunit of the condensin complex (Smc2p-Smc4p-Ycs4p-Brn1p-Ycg1p); required for establishment and maintenance of chromosome condensation, chromosome segregation, chromatin binding of condensin and silencing at the mating type locus | LOC7 | T |
| YHL027W | RIM101 | Transcriptional repressor involved in the response to pH; required for alkaline pH-stimulated differentiation pathways such as haploid invasive growth and sporulation; activated by proteolytic processing; has similarity to the A. nidulans transcription factor PacC | RIM1 | F |
| YLR287C-A | RPS30A | Protein component of the small (40S) ribosomal subunit; nearly identical to Rps30Bp and has similarity to rat S30 ribosomal protein | | T |
| YGR034W | RPL26B | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA | | T |
| YGR118W | RPS23A | Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Bp and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal | | T |
| YGR026W | YGR026W | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery | | F |
| YNL151C | RPC31 | RNA polymerase III subunit C31; contains HMG-like C-terminal domain | ACP2, C31, RPC8 | T |
| YHR146W | CRP1 | Protein that binds to cruciform DNA structures | | T |
| YEL069C | HXT13 | Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose | | T |
| YKL081W | TEF4 | Translation elongation factor EF-1 gamma | EFC1 | T |
| YJR123W | RPS5 | Protein component of the small (40S) ribosomal subunit, the least basic of the non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; has similarity to E. coli S7 and rat S5 ribosomal proteins | | T |
| YKL144C | RPC25 | RNA polymerase III subunit C25 | C25, YKL1 | T |
| YNL113W | RPC19 | RNA polymerase subunit, common to RNA polymerases I and III | AC19 | T |
| YOL021C | DIS3 | Nucleolar exosome component, involved in rRNA processing and RNA degradation, binds Gsp1p/Ran and enhances the GEF activity of Srm1p, implicated in mitotic control, homologous to the E. coli RNase R of the RNase II family | RRP44 | F |
| YNL124W | NAF1 | Protein required for the assembly of box H/ACA snoRNPs and for pre-rRNA processing, forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; has similarity to Gar1p and other RNA-binding proteins | | F |
| YER025W | GCD11 | Gamma subunit of the translation initiation factor eIF2, involved in the identification of the start codon; binds GTP when forming the ternary complex with GTP and tRNAi-Met | SUI4, eIF2 gamma | F |
| YEL036C | ANP1 | Subunit of the alpha-1,6 mannosyltransferase complex; type II membrane protein; has a role in retention of glycosyltransferases in the Golgi; involved in osmotic sensitivity and resistance to aminonitrophenyl propanediol | GEM3, MNN8 | F |
| YER110C | KAP123 | Karyopherin beta, mediates nuclear import of ribosomal proteins prior to assembly into ribosomes and import of histones H3 and H4; localizes to the nuclear pore, nucleus, and cytoplasm; exhibits genetic interactions with RAI1 | YRB4 | T |
| YPL013C | MRPS16 | Mitochondrial ribosomal protein of the small subunit | | T |
| YJL200C | ACO2 | Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol | | T |
| YDR002W | YRB1 | Ran GTpase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1 | CST20, HTN1, SFO1 | T |
| YAL007C | ERP2 | Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles | | T |
| YBR154C | RPB5 | RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III; contacts DNA and affects transactivation | ABC27 | T |
| YER057C | HMF1 | Member of the p14.5 protein family with similarity to Mmf1p, functionally complements Mmf1p function when targeted to mitochondria; heat shock inducible; high-dosage growth inhibitor; forms a homotrimer in vitro | HIG1 | T |
| YGL137W | SEC27 | Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP | | F |
| YGL008C | PMA1 | Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plasma membrane potential; part of the P2 subgroup of cation-transporting ATPases | | T |
| YBR086C | IST2 | Plasma membrane protein that may be involved in osmotolerance, localizes to the mother cell in small-budded cells and to the bud in medium- and large-budded cells; mRNA is transported to the bud tip by an actomyosin-driven process | | T |
| YOL127W | RPL25 | Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif | | F |
| YOR207C | RET1 | Second-largest subunit of RNA polymerase III, which is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs | C128, PDS2, RPC128, RPC2 | T |
| YFL010C | WWM1 | WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes Gi phase growth arrest and clonal death that is suppressed by overexpression of MCA1 | | T |
| YLR086W | SMC4 | Subunit of the condensin complex, which reorganizes chromosomes during cell division, forms a stable complex with Smc2p that has ATP-hydrolyzing and DNA-binding activity and promotes knotting of circular DNA; potential Cdc28p substrate | | F |
| YMR303C | ADH2 | Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde; involved in the production of certain carboxylate esters; regulated by ADR1 | ADR2 | T |
| YIR012W | SQT1 | Essential protein involved in a late step of 60S ribosomal subunit assembly or modification; contains multiple WD repeats; interacts with Qsr1p in a two-hybrid assay | | T |
| YLR293C | GSP1 | GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; regulated by Prp20p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and Kap95p; yeast Gsp2p homolog | CNR1, CST17 | T |
| YMR075W | RCO1 | Nuclear protein of unknown function | | F |
| YGR185C | TYS1 | Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase that aminoacylates tRNA(Tyr), required for cytoplasmic protein synthesis, interacts with positions 34 and 35 of the anticodon of tRNATyr | TTS1, TyrRS | T |
| YBR249C | ARO4 | 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine | | T |
| YCR098C | GIT1 | Plasma membrane permease, mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability | | T |
| YGL245W | GUS1 | Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm | GSN1, GluRS | T |
| YPR124W | CTR1 | High-affinity copper transporter of the plasma membrane, mediates nearly all copper uptake under low copper conditions; transcriptionally induced at low copper levels and degraded at high copper levels | | T |
| YBR106W | PHO88 | Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations | | T |
| YCR012W | PGK1 | 3-phosphoglycerate kinase, catalyzes transfer of high-energy phosphoryl groups from the acyl phosphate of 1,3-bisphosphoglycerate to ADP to produce ATP; key enzyme in glycolysis and gluconeogenesis | | T |
| YOL158C | ENB1 | Endosomal ferric enterobactin transporter, expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment | ARN4 | T |
| YBL031W | SHE1 | Cytoskeletal protein of unknown function; overexpression causes growth arrest | | T |
| YDR156W | RPA14 | RNA polymerase I subunit A14 | A14 | T |
| YKL006C-A | SFT1 | Intra-Golgi v-SNARE, required for transport of proteins between an early and a later Golgi compartment | | T |
| YMR235C | RNA1 | GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport | | T |
| YDR448W | ADA2 | Transcription coactivator, component of the ADA and SAGA transcriptional adaptor/HAT (histone acetyltransferase) complexes | SWI8 | T |
| YPL237W | SUI3 | Beta subunit of the translation initiation factor eIF2, involved in the identification of the start codon; proposed to be involved in mRNA binding | eIF2 beta | T |
| YFL001W | DEG1 | Non-essential tRNA:pseudouridine synthase, introduces pseudouridines at position 38 or 39 in tRNA, important for maintenance of translation efficiency and normal cell growth, localizes to both the nucleus and cytoplasm | PUS3 | T |
| YNL248C | RPA49 | RNA polymerase I subunit A49 | A49 | T |
| YCL050C | APA1 | Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa2p | DTP1 | F |
| YGL029W | CGR1 | Protein involved in nucleolar integrity and processing of the pre-rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress | | T |
| YBR245C | ISW1 | Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation, and a complex with Ioc3p to repress transcription initiation | SGN2 | F |
| YAR015W | ADE1 | N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine | | T |
| YML063W | RPS1B | Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Ap and has similarity to rat S3a ribosomal protein | PLC2, RP10B | T |
| YNR003C | RPC34 | RNA polymerase III subunit C34; interacts with TFIIIB70 and is a key determinant in pol III recruitment by the preinitiation complex | C34 | T |
| YGL055W | OLE1 | Fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria | MDM2 | T |
| YOR337W | TEA1 | Ty1 enhancer activator required for full levels of Ty enhancer-mediated transcription; C6 zinc cluster DNA-binding protein | | T |
| YBL076C | ILS1 | Cytoplasmic isoleucine-tRNA synthetase, target of the G1-specific inhibitor reveromycin A | | T |
| YOR303W | CPA1 | Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor; translationally regulated by an attenuator peptide encoded by YOR302W within the CPA1 mRNA 5'-leader | | T |
| YJR010W | MET3 | ATP sulfurylase, catalyzes the primary step of intracellular sulfate activation, essential for assimilatory reduction of sulfate to sulfide, involved in methionine metabolism | | T |
| YBR115C | LYS2 | Alpha aminoadipate reductase, catalyzes the reduction of alpha-aminoadipate to alpha-aminoadipate 6-semialdehyde, which is the fifth step in biosynthesis of lysine; activation requires posttranslational phosphopantetheinylation by Lys5p | | T |
| YOR182C | RPS30B | Protein component of the small (40S) ribosomal subunit; nearly identical to Rps30Ap and has similarity to rat S30 ribosomal protein | | T |
| YGR229C | SMI1 | Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity | KNR4 | F |
| YDR346C | SVF1 | Protein with a potential role in cell survival pathways, required for the diauxic growth shift; expression in mammalian cells increases survival under conditions inducing apoptosis | SGI1 | T |
| YJL138C | TIF2 | Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G | | T |
| YPR110C | RPC40 | RNA polymerase subunit, common to RNA polymerase I and III | AC40, RPC5 | T |
| YJL075C | APQ13 | Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 85% of ORF overlaps the verified gene NET1 | | T |
| YOR020C | HSP10 | Mitochondrial matrix co-chaperonin that inhibits the ATPase activity of Hsp60p, a mitochondrial chaperonin; involved in protein folding and sorting in the mitochondria; 10 kD heat shock protein with similarity to E. coli groES | CPN10 | T |
| YJL134W | LCB3 | Long-chain base-1-phosphate phosphatase, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids | LBP1, YSR2 | T |
| YLR333C | RPS25B | Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein | | T |
| YDR143C | SAN1 | Ubiquitin-protein ligase, involved in the proteasome-dependent degradation of aberrant nuclear proteins; san1 mutations suppress sir4, spt16, and cdc68 mutations, suggesting a role in chromatin silencing | | T |
| YMR300C | ADE4 | Phosphoribosylpyrophosphate amidotransferase (PRPPAT; amidophosphoribosyltransferase), catalyzes first step of the 'de novo' purine nucleotide biosynthetic pathway | | T |
| YDR037W | KRS1 | Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis | GCD5 | T |
| YPR194C | OPT2 | Oligopeptide transporter; member of the OPT family, with potential orthologs in S. pombe and C. albicans | | T |
| YBR143C | SUP45 | Polypeptide release factor involved in translation termination; mutant form acts as a recessive omnipotent suppressor | SAL4, SUP1, SUP47, eRF1 | T |
| YLL061W | MMP1 | High-affinity S-methylmethionine permease, required for utilization of S-methylmethionine as a sulfur source; has similarity to S-adenosylmethionine permease Sam3p | | T |
| YPL036W | PMA2 | Plasma membrane H+-ATPase, isoform of Pma1p, involved in pumping protons out of the cell; regulator of cytoplasmic pH and plasma membrane potential | | T |
| YGR187C | HGH1 | Protein of unknown function with similarity to human HMG1 and HMG2; localizes to the cytoplasm | | T |
| YKR039W | GAP1 | General amino acid permease; localization to the plasma membrane is regulated by nitrogen source | | T |
| YLR303W | MET17 | O-acetyl homoserine-O-acetyl serine sulfhydrylase, required for sulfur amino acid synthesis | MET15, MET25 | T |
| YKL060C | FBA1 | Fructose 1,6-bisphosphate aldolase, a cytosolic enzyme required for glycolysis and gluconeogenesis; catalyzes the conversion of fructose 1,6 bisphosphate into two 3-carbon products: glyceraldehyde-3-phosphate and dihydroxyacetone phosphate | LOT1 | T |
| YLR441C | RPS1A | Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Bp and has similarity to rat S3a ribosomal protein | RP10A | T |
| YDR399W | HPT1 | Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome | BRA6, HGPRTase, HPRT | T |
| YKR059W | TIF1 | Translation initiation factor eIF4A, identical to Tif2p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G | | T |
| YPL243W | SRP68 | Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane | | T |
| YAL003W | EFB1 | Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site | EF-1 beta, TEF5 | T |
| YCR024C-A | PMP1 | Small single-membrane span proteolipid that functions as a regulatory subunit of the plasma membrane H(+)-ATPase Pma1p, forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines | | T |
| YGR085C | RPL11B | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Ap; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11 | | T |
| YBR010W | HHT1 | One of two identical histone H3 proteins (see also HHT2); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation | BUR5, SIN2 | T |
| YPL075W | GCR1 | Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p | LPF10 | F |
| YOR098C | NUP1 | Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate | | F |
| YLR291C | GCD7 | Beta subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression | | F |
| YNL189W | SRP1 | Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation | KAP60, SCM1 | F |
| YML072C | TCB3 | Contains three calcium and lipid binding domains; localized to the bud; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; mRNA is targeted to the bud via the mRNA transport system involving She2p; C-terminal portion of Tcb1p, Tcb2p and Tcb3p interact | | T |
| YDR170C | SEC7 | Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles | | T |
| YNL209W | SSB2 | Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in the folding of newly-synthesized polypeptide chains; member of the HSP70 family; homolog of SSB1 | YG103 | T |
| YDL185W | TFP1 | Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding sites; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease | CLS8, VMA1 | T |
| YPL098C | MGR2 | Protein required for growth of cells lacking the mitochondrial genome | | T |
| YBR155W | CNS1 | TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70) and stimulates the ATPase activity of SSA1, ts mutants reduce Hsp82p function while over expression suppresses the phenotypes of an HSP82 ts allele and a cpr7 deletion | | T |
| YBL068W | PRS4 | 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of a five related enzymes, which are active as heteromultimeric complexes | | T |
| YDL145C | COP1 | Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicles in the early secretory pathway | RET1, SEC33, SOO1 | T |
| YNL216W | RAP1 | DNA-binding protein involved in either activation or repression of transcription, depending on binding site context; also binds telomere sequences and plays a role in telomeric position effect (silencing) and telomere structure | GRF1, TBA1, TUF1 | F |
| YJL130C | URA2 | Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes the first two enzymatic steps in the de novo biosynthesis of pyrimidines; both activities are subject to feedback inhibition by UTP | | F |
| YDL192W | ARF1 | ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p | | T |