| ID | Symbol | Description | Aliases | Front Node |
| YOL072W | THP1 | Nuclear pore-associated protein, forms a complex with Sac3p that is involved in transcription and in mRNA export from the nucleus; contains a PAM domain implicated in protein-protein binding | BUD29 | F |
| YGR015C | YGR015C | Hypothetical protein | | F |
| YJR063W | RPA12 | RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex | A12.2, RRN4 | F |
| YHR123W | EPT1 | sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase; not essential for viability | | T |
| YBR293W | VBA2 | Permease of basic amino acids in the vacuolar membrane | | T |
| YMR205C | PFK2 | Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes | | F |
| YNL097C | PHO23 | Probable component of the Rpd3 histone deacetylase complex, involved in transcriptional regulation of PHO5; C-terminus has similarity to human candidate tumor suppressor p33(ING1) | | T |
| YGL158W | RCK1 | Protein kinase involved in the response to oxidative stress; identified as suppressor of S. pombe cell cycle checkpoint mutations | | T |
| YIL078W | THS1 | Threonyl-tRNA synthetase, essential cytoplasmic protein | | F |
| YDR231C | COX20 | Mitochondrial inner membrane protein, required for proteolytic processing of Cox2p and its assembly into cytochrome c oxidase | | T |
| YHL048W | COS8 | Nuclear membrane protein, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; regulation suggests a potential role in the unfolded protein response | | T |
| YNL135C | FPR1 | Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function | FKB1, FKBP12, RBP1 | F |
| YDR077W | SED1 | Major stress-induced structural GPI-cell wall glycoprotein in stationary-phase cells, associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites | | T |
| YGL179C | TOS3 | Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome | | T |
| YNL214W | PEX17 | Peroxisomal membrane protein component of the peroxisomal translocation machinery, required for peroxisome biogenesis, binds Pex14p | PAS9 | T |
| YLR109W | AHP1 | Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p | cTPxIII | T |
| YML024W | RPS17A | Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Bp and has similarity to rat S17 ribosomal protein | RP51A, RPL51A | F |
| YJL089W | SIP4 | C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus | | T |
| YHR006W | STP2 | Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes | | T |
| YGR295C | COS6 | Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins | | T |
| YGL115W | SNF4 | Protein kinase activator found in a complex containing Snf1p and members of the Sip1p/Sip2p/Gal83p family; activates the Snf1p protein kinase; involved in expression of glucose-repressed genes, sporulation, and peroxisome biogenesis | CAT3, SCI1 | F |
| YOR079C | ATX2 | Golgi membrane protein involved in manganese homeostasis; overproduction suppresses the sod1 (copper, zinc superoxide dismutase) null mutation | YOR29-30 | F |
| YDL214C | PRR2 | Protein kinase with a possible role in MAP kinase signaling in the pheromone response pathway | | T |
| YHL021C | FMP12 | The authentic, non-tagged protein was localized to the mitochondria | | T |
| YPR160W | GPH1 | Non-essential glycogen phosphorylase required for the mobilization of glycogen, activity is regulated by cyclic AMP-mediated phosphorylation, expression is regulated by stress-response elements and by the HOG MAP kinase pathway | | F |
| YGR228W | YGR228W | Hypothetical protein | | F |
| YHR002W | LEU5 | Mitochondrial carrier protein involved in the accumulation of CoA in the mitochondrial matrix; homolog of human Graves disease protein; does not encode an isozyme of Leu4p, as first hypothesized | | T |
| YPL139C | UME1 | Negative regulator of meiosis, required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p, Wtm2p | WTM3 | F |
| YDL128W | VCX1 | Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter | HUM1, MNR1 | T |
| YDR032C | PST2 | Protein of unknown function with similarity to members of a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; GFP-fusion protein localizes to the cytoplasm in a punctate pattern | | T |
| YBR290W | BSD2 | Heavy metal ion homeostasis protein, facilitates trafficking of Smf1p and Smf2p metal transporters to the vacuole where they are degraded, controls metal ion transport, prevents metal hyperaccumulation, functions in copper detoxification | | T |
| YHR090C | YNG2 | Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has similarity to the human tumor suppressor ING1 | EAF4, NBN1 | F |
| YPR028W | YOP1 | Membrane protein that interacts with Yip1p to mediate membrane traffic; overexpression results in cell death and accumulation of internal cell membranes; regulates vesicular traffic in stressed cells | YIP2 | T |
| YBR054W | YRO2 | Putative plasma membrane protein of unknown function, transcriptionally regulated by Haa1p; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud | | T |
| YFL062W | COS4 | Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins | | T |
| YJL108C | PRM10 | Pheromone-regulated protein, predicted to have 5 transmembrane segments | | T |
| YCR004C | YCP4 | Protein of unknown function, has sequence and structural similarity to flavodoxins; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern | | T |
| YPR063C | YPR063C | Hypothetical protein | | F |
| YGR024C | THG1 | tRNAHis guanylyltransferase, adds a guanosine residue to the 5' end of tRNAHis after transcription and RNase P cleavage; couples nuclear division and migration to cell budding and cytokinesis; essential enzyme conserved among eukaryotes | | T |
| YIR038C | GTT1 | ER associated glutathione S-transferase capable of homodimerization; expression induced during the diauxic shift and throughout stationary phase; functional overlap with Gtt2p, Grx1p, and Grx2p | | T |
| YBR038W | CHS2 | Chitin synthase II, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for the synthesis of chitin in the primary septum during cytokinesis | | F |
| YPR106W | ISR1 | Predicted protein kinase, overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C | | T |
| YHR044C | DOG1 | 2-deoxyglucose-6-phosphate phosphatase, similar to Dog2p, member of a family of low molecular weight phosphatases; confers 2-deoxyglucose resistance when overexpressed, in vivo substrate has not yet been identified | | T |
| YBR212W | NGR1 | RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; expressed in stationary phase | RBP1 | T |
| YKL090W | CUE2 | Protein of unknown function; has two CUE domains that bind ubiquitin, which may facilitate intramolecular monoubiquitination | | F |
| YGL221C | NIF3 | Protein of unknown function, similar to Listeria monocytogenes major sigma factor (rpoD gene product) | | T |
| YBR052C | RFS1 | Protein of unknown function; member of a flavodoxin-like fold protein family that includes Pst2p and Ycp4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern | | T |
| YDL234C | GYP7 | GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking | | T |
| YER027C | GAL83 | One of three possible beta-subunits of the Snf1 kinase complex, allows nuclear localization of the Snf1 kinase complex in the presence of a nonfermentable carbon source; contains glycogen-binding domain | SPM1 | F |
| YDL116W | NUP84 | Subunit of the nuclear pore complex (NPC), forms a subcomplex with Nup85p, Nup120p, Nup145p-C, Sec13p, and Seh1p that plays a role in nuclear mRNA export and NPC biogenesis | | F |
| YML110C | COQ5 | 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase, involved in ubiquinone (Coenzyme Q) biosynthesis; located in mitochondria | DBI56 | T |
| YPL057C | SUR1 | Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p | BCL21, CSG1, LPE15 | T |
| YNL009W | IDP3 | Peroxisomal NADP-dependent isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate with the formation of NADP(H+), required for growth on unsaturated fatty acids | | T |
| YNL192W | CHS1 | Chitin synthase I, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for repairing the chitin septum during cytokinesis; transcription activated by mating factor | USA4 | T |
| YOR279C | RFM1 | DNA-binding protein required for vegetative repression of middle sporulation genes; specificity factor that directs the Hst1p histone deacetylase to some of the promoters regulated by Sum1p; involved in telomere maintenance | | T |
| YOR106W | VAM3 | Syntaxin-related protein required for vacuolar assembly; functions with Vam7p in vacuolar protein trafficking; member of the syntaxin family of proteins | PTH1 | F |
| YJL198W | PHO90 | Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth | | F |
| YGL153W | PEX14 | Peroxisomal membrane protein that is a central component of the peroxisomal protein import machinery, interacts with PTS1 (Pex5p) and PTS2 (Pex7p) peroxisomal matrix protein signal recognition factors and membrane receptor Pex13p | | F |
| YDR082W | STN1 | Telomere end-binding and capping protein, plays a key role with Pol12p in linking telomerase action with completion of lagging strand synthesis, and in a regulatory step required for telomere capping | | T |
| YGR062C | COX18 | Mitochondrial inner membrane protein, required for export of the Cox2p C terminus from the mitochondrial matrix to the intermembrane space during its assembly into cytochrome c oxidase; similar to Oxa2p of N. crassa | OXA2 | F |
| YER162C | RAD4 | Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human XPC protein | | T |
| YPL087W | YDC1 | Alkaline dihydroceramidase, involved in sphingolipid metabolism; preferentially hydrolyzes dihydroceramide to a free fatty acid and dihydrosphingosine; has a minor reverse activity | | T |
| YDR380W | ARO10 | Phenylpyruvate decarboxylase, catalyzes decarboxylation of phenylpyruvate to phenylacetaldehyde, which is the first specific step in the Ehrlich pathway | | T |
| YOR245C | DGA1 | Diacylglycerol acyltransferase, catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor, localized to lipid particles | | T |
| YLR248W | RCK2 | Protein kinase involved in the response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations | CLK1, CMK3 | T |
| YLR284C | ECI1 | Peroxisomal delta3,delta2-enoyl-CoA isomerase, hexameric protein that converts 3-hexenoyl-CoA to trans-2-hexenoyl-CoA, essential for the beta-oxidation of unsaturated fatty acids, oleate-induced | | T |
| YDL107W | MSS2 | Peripherally bound inner membrane protein of the mitochondrial matrix, required for export of C-terminal tail of Cox2p through the inner membrane | | T |
| YBL050W | SEC17 | Peripheral membrane protein required for vesicular transport between ER and Golgi and for the 'priming' step in homotypic vacuole fusion, part of the cis-SNARE complex; has similarity to alpha-SNAP | | T |
| YBR302C | COS2 | Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins | | T |
| YLR237W | THI7 | Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia | THI10 | F |
| YHL020C | OPI1 | Transcriptional regulator of a variety of genes; phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes; involved in telomere maintenance | | F |
| YIL031W | ULP2 | Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins, plays a role in chromosome cohesion at centromeric regions and recovery from checkpoint arrest induced by DNA damage or DNA replication defects; potential Cdc28p substrate | SMT4 | T |
| YOR347C | PYK2 | Pyruvate kinase that appears to be modulated by phosphorylation; PYK2 transcription is repressed by glucose, and Pyk2p may be active under low glycolytic flux | | T |
| YOR016C | ERP4 | Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport | | F |
| YGR002C | SWC4 | Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin; component of the NuA4 histone acetyltransferase complex | EAF2, GOD1 | T |
| YOR089C | VPS21 | GTPase required for transport during endocytosis and for correct sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog | VPS12, VPT12, YPT21, YPT51 | T |
| YLR178C | TFS1 | Carboxypeptidase Y inhibitor, function requires acetylation by the NatB N-terminal acetyltransferase; phosphatidylethanolamine-binding protein involved in protein kinase A signaling pathway | DKA1 | T |
| YDR178W | SDH4 | Membrane anchor subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone | ACN18 | T |
| YOL032W | OPI10 | | | T |
| YDR204W | COQ4 | Protein with a role in ubiquinone (Coenzyme Q) biosynthesis, possibly functioning in stabilization of Coq7p; located on the matrix face of the mitochondrial inner membrane; component of a mitochondrial ubiquinone-synthesizing complex | | T |
| YCR036W | RBK1 | Putative ribokinase | | T |
| YDR038C | ENA5 | Protein with similarity to P-type ATPase sodium pumps | | T |
| YMR302C | PRP12 | Integral inner mitochondrial membrane protein with similarity to exonucleases; prp12 mutants exhibit an increased rate of mt DNA escape | RNA12, YME2 | T |
| YOR370C | MRS6 | Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is required for the prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p) | MSI4 | F |
| YML132W | COS3 | Protein involved in salt resistance; interacts with sodium:hydrogen antiporter Nha1p; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins | | T |
| YDR190C | RVB1 | Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family | TIH1, TIP48, TIP49A | F |
| YDR058C | TGL2 | Protein with lipolytic activity towards triacylglycerols and diacylglycerols when expressed in E. coli; role in yeast lipid degradation is unclear | | T |
| YLR273C | PIG1 | Putative targeting subunit for the type-1 protein phosphatase Glc7p that tethers it to the Gsy2p glycogen synthase | | T |
| YPL091W | GLR1 | Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glutathione | LPG17 | T |
| YKL096W | CWP1 | Cell wall mannoprotein, linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; involved in cell wall organization | YJU1 | T |
| YLR174W | IDP2 | Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose | | T |
| YDL220C | CDC13 | Single stranded DNA-binding protein found at TG1-3 telomere G-tails; regulates telomere replication through recruitment of specific sub-complexes, but the essential function is telomere capping | EST4 | F |
| YKL012W | PRP40 | U1 snRNP protein involved in splicing, interacts with the branchpoint-binding protein during the formation of the second commitment complex | | F |
| YMR243C | ZRC1 | Vacuolar membrane zinc transporter, transports zinc from the cytosol into the vacuole for storage; also has a role in resistance to zinc shock resulting from a sudden influx of zinc into the cytoplasm | OSR1 | F |
| YOR142W | LSC1 | Alpha subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate | | T |
| YDR369C | XRS2 | Protein required for DNA repair; component of the Mre11 complex, which is involved in double strand breaks, meiotic recombination, telomere maintenance, and checkpoint signaling | | F |
| YCR068W | ATG15 | Lipase, required for intravacuolar lysis of autophagic bodies; located in the endoplasmic reticulum membrane and targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway | AUT5, CVT17 | T |
| YNL139C | RLR1 | Subunit of the THO complex, which is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids | LDB5, THO2, ZRG13 | F |
| YBR035C | PDX3 | Pyridoxine (pyridoxamine) phosphate oxidase, has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism | | T |