2012
|
 |
| MGMR: leveraging RNA-Seq population data to optimize expression estimation. |
| R. Rozov, E. Halperin and R. Shamir. |
BMC Bioinformatics, Proceedings of the Second Annual RECOMB Satellite Workshop on Massively Parallel Sequencing (RECOMB-seq 2012), 13(Suppl 6):S2, 2012.
|
|
 |
| Transcriptional and Proteomic Analysis of the Aspergillus fumigatus DprtT Protease-Deficient Mutant. |
| S.Hagag, P. Kubitschek-Barreira, G. W. P. Neves, D. Amar, W. Nierman, I. Shalit, R. Shamir, L. Lopes-Bezerra, N. Osherov. |
PLoS ONE, Volume 7, Issue 4, e33604, 2012.
|
|
 |
| A novel candidate cis-regulatory motif pair in the promoters of germline and oogenesis genes in C. elegans. |
| C. Linhart, Y. Halperin, A. Darom, S. Kidron, L. Broday and R. Shamir. |
Genome Research,22(1):76-83, 2012.
|
|
 |
| Constructing logical models of gene regulatory networks by integrating transcription factor-DNA interactions with expression data: an entropy based approach. |
| G. Karlebach and R. Shamir. |
Journal of Computational Biology19(1): 30-41, 2012.
|
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2011
|
 |
| A Point Mutation in Translation Initiation Factor eIF2B Leads to Function- and Time-Specific Changes in Brain Gene Expression. |
| L. Marom, I. Ulitsky, Y. Cabilly, R. Shamir, O. Elroy-Stein. |
PLoS ONE, 6, 269920, 2011.
|
|
 |
| Bioinformatics for Biologists. |
| P. Pevzner and R. Shamir, editors
. |
|
Textbook. Cambridge University Press, UK, 2011.
|
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|
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An O(n3/2√log(n)) algorithm for sorting by reciprocal translocations.
|
| M. Ozery-Flato, R. Shamir. |
Journal of Discrete Algorithms, Volume 9, Issue 4, Pages 344-357(2011),
|
|
 |
| Detecting Highways of Horizontal Gene Transfer. |
| M. S. Bansal, G. Banay, J. P. Gogarten and R. Shamir. |
J. of Computational Biology, September 2011, 18(9): 1087-1114. doi:10.1089/cmb.2011.0066
|
|
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| Transcriptional Modulation Induced By Ionizing Radiation: P53 Remains A Central Player. |
| S.Rashi-Elkeles, R. Elkona, S. Shavit, Y. Lerenthal, C. Linhart, A. Kupershtein, N. Amariglio, G. Rechavi, R. Shamir and Y. Shiloh. |
Molecular Oncology, 5, 336-348, 2011
|
|
 |
| Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy. |
| Ozery-Flato M, Linhart C, Trakhtenbrot L, Izraeli S, Shamir R. |
Genome Biology, 29;12(6):R61, 2011
|
|
 |
| Selected papers from the 2nd RECOMB satellite meeting on Bioinformatics Education (RECOMB-BE). |
| P. A. Pevzner, R. Shamir, editors. |
|
To appear in Journal of Computational Biology, 18 (7), 2011.
|
|
 |
| A note on the fixed parameter tractability of the gene-duplication problem. |
| Bansal, M.S. and Shamir, R. |
IEEE/ACM Transactions on Computational Biology and Bioinformatics, 8 (3), art. no. 5557848, pp. 848-850, 2011
|
|
 |
| Integration of Transcriptomics, Proteomics, and MicroRNA Analyses Reveals Novel MicroRNA Regulation
of Targets in the Mammalian Inner Ear. |
| T. Elkan-Miller, I. Ulitsky, R. Hertzano, A. Rudnicki, A. A. Dror, D. R. Lenz, R. Elkon, M. Irmler, J. Beckers, R. Shamir, K.B. Avraham. |
PLoS One, Volume 6,Issue 4, e18195, 2011
|
|
 |
| PrtT-Regulated Proteins Secreted by Aspergillus fumigatus Activate MAPK Signaling
in Exposed A549 Lung Cells Leading to Necrotic Cell Death. |
| H. Sharon, D. Amar, E. Levdansky, G. Mircus, Y. Shadkchan, R. Shamir, N. Osherov. |
PLoS One, Volume 6, Issue 3, e17509, 2011
|
|
 |
| Dynamic Changes in the Copy Number of Pluripotency and Cell Proliferation Genes
in Human ESCs and iPSCs during Reprogramming and Time in Culture. |
| L.C. Laurent, I.Ulitsky, I.Slavin, H. Tran, A. Schork, R. Morey, C. Lynch,
J.V. Harness, S. Lee, M.J. Barrero, S. Ku, M. Martynova, R. Semechkin, V. Galat,
J. Gottesfeld, J.C. Izpisua Belmonte, C. Murry, H. S. Keirstead, H.-S. Park,
U. Schmidt, A.L. Laslett, F.-J. Muller, C. M. Nievergelt, R. Shamir and J. F. Loring. |
Cell Stem Cell, doi: 10.1016/j.stem.2010.12.003,2011.
|
|
 |
| SPIKE: a database of highly curated human signaling pathways. |
| A. Paz, Z. Brownstein, Y. Ber, S. Bialik, E. David, D. Sagir, I. Ulitsky, R. Elkon,
A. Kimchi, K. B. Avraham, Y. Shiloh and R. Shamir. |
Nucleic Acids Research, Vol. 39, Database issue D793-D799, 2011.
|
|
2010
|
 |
| DEGAS: De Novo Discovery of Dysregulated Pathways in Human Diseases. |
| Igor Ulitsky, Akshay Krishnamurthy, Richard M. Karp, Ron Shamir. |
PLoS One , 5 (10) e13367 (2010).
|
|
 |
| Detecting Highways of Horizontal Gene Transfer. |
| Mukul S. Bansal, J. Peter Gogarten, and Ron Shamir. |
8th Annual RECOMB Comparative Genomics Workshop (RECOMB-CG 2010), LNCS, 6398: 109-120 (2010).
|
|
 |
| PAKDD Data Mining Competition 2009: New Ways of Using Known Methods. |
| Chaim Linhart, Guy Harari, Sharon Abramovich and Altina Buchris. |
|
Lecture Notes in Computer Science, Volume 5669/2010, 99-105, DOI: 10.1007/978-3-642-14640-4_7 (2010).
|
|
 |
| A Faster Algorithm for Simultaneous Alignment and Folding of RNA. |
| Ziv-Ukelson M, Gat-Viks I, Wexler Y, Shamir R. |
Journal of Computational Biology,17(8):1051-65,2010.
|
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|
|
Towards computational prediction of microRNA function and activity.
|
| I. Ulitsky, L. C. Laurent and R. Shamir. |
Nucleic Acids Research, 38 (15): e160. pp 1-13 (2010).
|
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|
|
A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking.
|
| P.S. Aguilar, F. Fröhlich, M. Rehman, M. Shales, I. Ulitsky, A. Olivera-Couto, H. Braberg, R. Shamir, P. Walter, M. Mann, C.S. Ejsing, N.J. Krogan, T.C. Walther. |
Nature Structural and Molecular Biology
, Vol. 17 no. 7, pp 901-909(2010).
|
|
|
|
Topology-free querying of protein interaction networks.
|
| Bruckner, S., Hüffner, F., Karp, R.M., Shamir, R., Sharan, R. |
Journal of Computational Biology
, 17 (3), pp. 237-252 (2010).
|
|
|
|
Minimally perturbing a gene regulatory network to avoid a disease phenotype: the glioma network as a test case.
|
| G. Karlebach, R. Shamir . |
BMC Systems Biology
, 4:15 doi:10.1186/1752-0509-4-15(2010).
|
|
|
|
Ras inhibits ER Stress in Human Cancer Cells with Amplified Myc.
|
| S. Yaari-Stark, M. Shaked, Y. Nevo-Caspi, J. Jacob-Hircsh, R. Shamir, G. Rechavi, Y. Kloog. |
International Journal of Cancer
, Vol 126, 2268--2281 (2010).
|
|
|
|
Special issues dedicated to Michael Waterman on the occasion of his 67th birthday.
|
| S. Istrail, P. Pevzner, R. Shamir. F. Sun, guest editors. | |
Communication in Information and Systems
, Vol 9 3-4 (2009), Vol 10 1-2 (2010).
|
|
|
|
Different sets of QTLs influence fitness variation in yeast.
|
| G. H. Romano, Y. Gurvich, O. Lavi, I. Ulitsky, R. Shamir, M. Kupiec. |
Molecular Systems Biology
6:346, doi:10.1038/msb.2010.1, 2010 .
|
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 |
|
Expander: from expression microarrays to networks and functions.
|
| I. Ulitsky, A. Maron-Katz, S. Shavit, D. Sagir, C. Linhart, R. Elkon, A. Tanay, R. Sharan, Y. Shiloh, R. Shamir. |
Nature Protocols
Vol 5, pp 303 - 322, 2010 .
|
|
|
|
Understanding gene sequence variation in the context of transcription regulation in yeast.
|
| I. Gat-Viks, R. Meller, M. Kupiec, R. Shamir. |
PLoS Genetics
, Vol. 6 No. 1 e1000800 (2010).
|
|
2009
|
|
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Towards accurate imputation of quantitative genetic interactions.
|
| I. Ulitsky, N.J. Krogan and R. Shamir. |
Genome Biology
, Volume 10:R140 2009 .
|
|
|
|
Assessing the Quality of Whole Genome Alignments in Bacteria.
|
| F. Swidan, R. Shamir. |
Advances in Bioinformatics
, Volume 2009, Article ID 749027, 8 pages doi:10.1155/2009/749027 (2009).
|
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|
Computing Has Changed Biology - Biology Education Must Catch Up.
|
| P. Pevzner, R. Shamir. |
Education Forum in Science
Vol. 325. no. 5940, pp. 541 - 542 (31 July 2009).
|
|
|
|
SlimPLS: a method for feature selection in gene expression-based disease classification.
|
| M. Gutkin, G. Dror, R. Shamir. |
PLoS One
Vol. 4 No. 7 e6416 (2009) .
|
|
|
|
A faster fixed-parameter approach to drawing binary tanglegrams.
|
| S. Bocker, F. Hüffner, A. Truss, and M. Wahlstrom. |
In Proceedings of the 4th International Workshop on Parameterized and Exact Computation,(IWPEC '09)
Copenhagen,Denmark,September 2009
Lecture Notes in Computer Science, Springer.
|
|
|
|
Torque: topology-free querying of protein interaction networks
|
| S. Bruckner, F. Hüffner, R. M. Karp, R. Shamir, R. Sharan. |
Nucleic Acids Research
doi: 10.1093/nar/gkp474.
|
|
 |
| Increasing the Power of Association Studies by Imputation-based Sparse Tag SNP Selection |
| O. Davidovich, G. Kimmel, E. Halperin, R. Shamir. |
Communications in Information and Systems 9 (3) 269-282 (2009)
|
|
 |
| Identifying functional modules using expression profiles and confidence-scored protein interactions |
| I. Ulitsky and R. Shamir. |
Bioinformatics
Vol. 25 no. 9 pages 1158-1164 (2009) .
|
|
 |
| Topology-free querying of protein interaction networks |
| S. Bruckner, F. Hüffner, R. M. Karp, R. Shamir, R. Sharan. |
Proceedings of RECOMB 2009 LNCS 5541 74-89,
|
|
 |
| Faster Pattern Matching with Character Classes using Prime Number Encoding |
| C. Linhart and R. Shamir. |
Journal of Computers and System Sciences
, 75, 155--162 (2009).
|
|
|
|
Allegro: Analyzing expression and sequence in concert to discover regulatory programs
|
| Y. Halperin, C. Linhart, I. Ulitsky and R. Shamir. |
Nucleic Acids Research
37:5, 1566-1579.
|
|
 |
| Matching with don't-cares and a small number of mismatches |
| C. Linhart and R. Shamir. |
Information Processing Letters
Volume 109, Number 5, p. 273-277 (2009).
|
|
2008
|
 |
| Sorting cancer karyotypes by elementary operations |
| M. Ozery-Flato and R. Shamir. |
Proceedings of the 6th RECOMB Satellite Workshop on Comparative
Genomics 2008,
LNCS Vol. 5267 pp. 211-225 (2008).
 |
|
 |
| A faster algorithm for RNA co-folding |
| M. Ziv-Ukelson, I. Gat-Viks, Y. Wexler and R. Shamir. |
Proc. Algorithms in Bioinformatics, Keith A. Crandall and Jens Lagergren (Eds.), 8th International Workshop, WABI 2008, LNBI 5251, 174-185, Karlsruh, Germany, September 15-17, (2008).
 |
|
 |
| Modeling and Analysis of Regulatory Networks |
| G. Karlebach and R. Shamir. |
Nature Reviews Molecular Cell Biology, Vol. 9
771--780 doi:10.1038/nrm2503 (2008)
 |
|
 |
| Regulatory networks define phenotypic classes of human stem cell lines. |
| F.J. Mueller, D. Kostka, L. Laurent, I. Ulitsky, R. Williams, C. Lu, M.S. Rao, R. Shamir, P.H. Schwartz,
N.O. Schmidt and J.F. Loring. |
Nature.
Vol. 455 No. 7211 p. 401-405 (2008)  |
|
 |
| Detecting pathways transcriptionally correlated with clinical parameters |
| I. Ulitsky and R. Shamir |
Proc. 7th Annual International Conference on Computational Systems Bioinformatics (CSB 08)
pp. 249--258, Imperial College Press, London, UK (2008)
 |
|
 |
| Sorting Genomes with Centromeres by Translocations |
| M. Ozery-Flato and R. Shamir |
Journal of Computational Biology (2008) Vol. 15 No. 7
 |
|
 |
| From E-MAPs to module maps: dissecting quantitative genetic interactions using physical interactions |
| I. Ulitsky, T. Shlomi, M. Kupiec and R. Shamir |
Molecular Systems Biology (2008) Vol. 4 doi:10.1038/msb.2008.42
 |
|
 |
| Transcription factor and microRNA motif discovery: The Amadeus platform and a compendium of metazoan target sets |
| C. Linhart, Y. Halperin and R. Shamir |
Genome Research (2008) Vol. 18 No. 7 1180-1189
 |
|
 |
| Comprehensive MicroRNA Profiling Reveals a Unique Human Embryonic Stem Cell Signature Dominated by a Single Seed Sequence |
| L.C. Laurent, J. Chen, I. Ulitsky, F.J. Mueller, C. Lu, R. Shamir, J.B. Fan and J.F. Loring |
Stem Cells doi: 10.1634/stemcells.2007-1081  |
|
 |
| Detecting Disease-Specific Dysregulated Pathways Via Analysis of Clinical Expression Profiles |
| I. Ulitsky, R.M. Karp and R. Shamir |
Proc. RECOMB 2008, pp. 347--359, LNBI 4955, Springer, Berlin, (2008).  |
|
 |
| SPIKE - a database, visualization and analysis tool of cellular signaling pathways |
| R. Elkon, R. Vesterman, N. Amit, I. Ulitsky, I. Zohar, M. Weisz, G. Mass, N. Orlev, G. Sternberg, R. Blekhman, J. Assa, Y. Shiloh and R.Shamir |
BMC Bioinformatics
(2008) Vol. 9 No. 11
 |
|
 |
| Computational Problems in Perfect Phylogeny Haplotyping: Typing without Calling the Allele |
| T. Barzuza, J.S. Beckmann, R. Shamir and I. Pe'er |
|
IEEE Transactions on Computational Biology and Bioinformatics
(2008) Vol. 5 No. 1 101-9 |
|
 |
| Evolution and Selection in Yeast Promoters: Analyzing the Combined Effect of Diverse Transcription Factor Binding Sites |
| D. Raijman, R. Shamir and A. Tanay |
PLoS Computational Biology
(2008) Vol. 4 No. 1
 |
|
 |
| MetaReg: A platform for modeling, analysis and visualization of biological systems using large-scale experimental data |
| I. Ulitsky, I. Gat-Viks and R. Shamir |
Genome Biology
(2008) Vol. 9 No. R1
 |
|
2007
|
 |
| On the frequency of genome rearrangement events in cancer karyotypes |
| M. Ozery-Flato and R. Shamir. |
Proc. RECOMB satellite on Computational Cancer Biology, 2007
|
|
 |
| Improved algorithms for the random cluster graph model |
| R. Shamir and D. Tsur |
Random Structures and Algorithms
31(4):418-449, 2007
 |
|
 |
| Pediatric Onset Crohn's Disease is Characterized by Age and Genotype- Related Colonic Susceptibility |
| A. Levine, S. Kugathasan, A. Vito, V. Biank, E. Leshinsky-Silver, O. Davidovich, G. Kimmel, R. Shamir, P. Orazio, U. Broeckel, S. Cucchiara. |
| Inflammatory Bowel Disease (2007) Vol. 13 No. 12 1509-15 |
|
 |
| Functional genomic delineation of TLR-induced transcriptional networks |
| R. Elkon, C. Linhart, Y. Halperin, Y. Shiloh and R. Shamir |
BMC Genomics (2007) Vol. 8 No. 394  |
|
 |
| A randomization test for controlling population stratification in whole-genome association studies |
| G. Kimmel, M.I. Jordan, E. Halperin, R. Shamir and R.M. Karp RM |
American Journal of Human Genetics (2007) , Vol. 81 No. 5, 895-905 (2007)  |
|
 |
|
 |
| Risk factors for perianal Crohn's disease: the role of genotype, phenotype, and ethnicity. |
| A. Karban, M. Itay, O. Davidovich, E. Leshinsky-Silver G. Kimmel, H. Fidder, R. Shamir, M. Waterman, R. Eliakim and A. Levine |
The American Journal of Gastroenterology, Vol 102, No. 8 1702-8 (2007)
 |
|
 |
| Third special issue on Computational Biology |
| R. M. Karp, M. Li, P. Pevzner, R. Shamir, Guest editors. |
| Journal of Computers and System Sciences Vol. 73, No. 7 (2007)
|
|
 |
| Pathway redundancy and protein essentiality revealed in the Saccharomyces cerevisiae interaction networks |
| I. Ulitsky and R. Shamir |
Molecular Systems Biology, Vol. 3, No. 88 (2007)
 |
|
 |
| Rearrangements in genomes with centromeres part I: translocations |
| M. Ozery-Flato and R. Shamir. |
Proc. RECOMB 2007, , pp. 339--353, LNBI 4453, Springer, Berlin (2007)  |
|
 |
| Network-based prediction of protein function |
| R. Sharan, I. Ulitsky and R. Shamir |
Molecular Systems Biology, Vol. 3, No. 88 (2007)
 |
|
 |
| Lack of association of the 3'-UTR polymorphism in the NFKBIA gene with Crohn's disease in an Israeli cohort |
| E. Leshinsky-Silver, A. Karban, S. Cohen, M. Fridlander, O. Davidowich, G. Kimmel, R. Shamir and A. Levine |
International Journal of Colorectal Disease (2007)
 |
|
 |
| Sorting by reciprocal translocations via reversals theory |
| M. Ozery-Flato and R. Shamir |
Journal of Computational Biology , Vol. 14 No. 4 (2007)
 |
|
 |
| A genome-wide analysis in Saccharomyces cerevisiae demonstrates the influence of chromatin modifiers on transcription |
| I. Steinfeld, R. Shamir and M. Kupiec |
Nature Genetics, Vol. 39, No. 3 (2007)
.  |
|
 |
| Fifth Special Issue in the Computational Molecular Biology Series |
| S. Istrail, P. Pevzner, R. Shamir, Editors |
| Discrete Applied Mathematics, Vol. 155, No. 6-7 (2007) |
|
 |
| Refinement and expansion of signaling pathways: The osmotic response network in yeast |
| I. Gat-Viks and R. Shamir |
Genome Research, Vol. 17, No. 3 (2007)
 |
|
 |
| GEVALT: An integrated software tool for genotype analysis |
| O. Davidovich, G. Kimmel and R. Shamir |
BMC Bioinformatics, Vol. 8, No. 36 (2007)
 |
|
 |
| Identification of functional modules using network topology and high-throughput data |
| I. Ulitsky and R. Shamir |
BMC Systems Biology, Vol. 1, No. 8 (2007)
 |
|
2006
|
 |
| Assessing the number of ancestral alternatively spliced exons in the human genome |
| R. Sorek, G. Dror and R. Shamir |
BMC Genomics, Vol. 7, pp. 273 (2006)
 |
|
 |
| Sorting by translocations via reversals theory |
| M. Ozery-Flato and R. Shamir |
Proc. 4th RECOMB Satellite on Comparative Genomics, Lecture Notes in Computer Science, Vol. 4205, pp. 87-98, Springer, Berlin (2006)
 |
|
 |
| Quantification of protein half-lives in the budding yeast proteome |
| A. Belle, A. Tanay, L. Bitincka, R. Shamir and E.K. O'Shea |
Proc. National Academy of Science USA, Vol. 103, No. 35, pp. 13004-13009 (2006)
 |
|
 |
| E2F1 identified by promoter and biochemical analysis as a central target of glioblastoma cell-cycle arrest in response to RAS inhbibition |
| R. Blum, I. Nakdimon, R. Elkon, R. Shamir, G. Rechavi and Y. Kloog |
International Journal of Cancer, Vol. 119, No. 3, pp. 527-538 (2006)
 |
|
 |
| A Fast Method for Computing High-Significance Disease Association in Large Population-Based Studies |
| G. Kimmel and R. Shamir |
American Journal of Human Genetics, Vol. 79, pp. 481-492 (2006)
 |
|
 |
| An O(n3/2√log(n)) algorithm for sorting by reciprocal translocations |
| M. Ozery-Flato and R. Shamir |
Proc. of CPM 2006, LNCS, Vol. 4009, pp. 258-269 (2006)
 |
|
 |
| A probabilistic methodology for integrating knowledge and experiments on biological networks |
| I. Gat-Viks, A. Tanay, D. Raijman and R. Shamir |
Journal of Computational Biology 2006 Mar;13(2):165-81  |
|
 |
| RAD51 haplotypes and breast cancer risk in Jewish non-Ashkenazi high risk women |
| I. Gal, G. Kimmel, R. Gershoni-Baruch, M. Z. Papa, E. Dagan, R. Shamir, E. Friedman |
European Journal of Cancer 42(8) pp. 1129-34 (2006)  |
|
 |
| ATM haplotypes and breast cancer risk in Jewish high risk women |
| M. Koren, G. Kimmel, E. Ben-Asher, I. Gal, M. Z. Papa, J. S. Beckman, D. Lancet, R. Shamir, E. Friedman |
British Journal of Cancer 94 (10) pp. 1537-1543 (2006)
 |
|
 |
|
 |
| A simpler and faster 1.5-approximation algorithm for sorting by transpositions |
| T. Hartman and R. Shamir |
Information and Computation 204 (2) 275-290 (2006)
 |
|
 |
| Parallel induction of ATM-dependent pro- and anti-apoptotic signals in response to ionizing radiation in murine lymphoid tissue |
| S. Rashi-Elkeles, R. Elkon, N. Weizman, C. Linhart, N. Amariglio, G. Sternberg, G. Rechavi, A. Barzilai, R. Shamir, Y. Shiloh |
Oncogene 25, 1584-1592 (2006)
 |
|
2005
|
| Identification of protein complexes by comparative analysis of yeast and bacterial protein interaction data |
| R. Sharan, T. Ideker, B. Kelley, R. Shamir, R. M. Karp |
Journal of Computational Biology Vol. 12 No. 6 pp. 835-846 (2005)
 |
|
| Deciphering Transcriptional Regulatory Elements That Encode Specific Cell-Cycle Phasing by Comparative Genomics Analysis |
| C. Linhart, R. Elkon, Y. Shiloh, and R. Shamir |
Cell Cycle Vol. 4(12), pp. 1788-1797 Dec 2005
 |
|
| EXPANDER: an integrative suite for microarray data analysis |
| R. Shamir, A. Maron-Katz, A. Tanay, C. Linhart, I. Steinfeld, R.Sharan, Y. Shiloh, R. Elkon |
BMC Bioinformatics 6:232 (2005)
 |
|
| A catalog of stability-associated sequence elements in 3~R UTRs of yeast
mRNAs |
| R. Shalgi, M. Lapidot, R. Shamir, Y. Pilpel |
Genome Biology 6:R86 (2005)
(website) |
|
| Tag SNP Selection in Genotype Data for Maximizing SNP Prediction
Accuracy |
| E. Halperin, G. Kimmel, R. Shamir. |
Proc. of ISMB 2005; Bioinformatics Vol. 21 Suppl. 1 pp. i195-i203 (2005)
 |
|
| Typing without calling the allele: a strategy for inferring SNP haplotypes |
| T. Barzuza, J. S. Beckmann, R. Shamir and I. Pe'er |
European Journal of Human Genetics Vol. 13, pp. 898-901 (2005)
 |
|
| Conservation and evolvability in regulatory networks: The evolution of ribosomal regulation in yeast |
| A. Tanay, A. Regev, R. Shamir |
Proc. National Academy of Science USA Vol. 102 No. 20, pp. 7203-7208 (2005)
 |
|
| Factor graph network models for biological systems |
| I. Gat-Viks, A. Tanay, D. Raijman, R. Shamir |
Proc. of RECOMB 2005 pp. 31-47, Lecture Notes in Bioinformatics 3500, Springer, Berlin, 2005
 |
|
| Dissection of a DNA damage-induced transcriptional network using a combination of microarrays, RNAi and computational promoter analysis |
| R. Elkon, S. Rashi-Elkeles, Y. Lerenthal, C. Linhart, T. Tenne, N. Amariglio, G. Rechavi, R. Shamir, Y. Shiloh |
Genome Biology 6: R43 (2005)
 |
|
| 2nd special issue of JCSS on Computational Biology |
| R. M. Karp, M. Li, P. Pevzner, R. Shamir, guest editors |
Journal of Computers and System Sciences Volume 70, No. 3, May 2005
 |
|
| A Block-Free Hidden Markov Model for Genotypes and Its Application to Disease Association |
| G. Kimmel and R. Shamir |
Journal of Computational Biology Volume 12, Number 10, pp. 1243-1260, 2005
 |
|
| Integrative analysis of genome-wide experiments in the context of a large high-throughput data compendium |
| A. Tanay, I. Steinfeld, M. Kupiec and R. Shamir |
Molecular Systems Biology doi: 10.1038/msb4100005 (2005)
 |
|
| A global view of pleiotropy and phenotypically derived gene function in yeast |
| A. M. Dudley, D. M. Janse, A. Tanay, R. Shamir, G. M. Church |
Molecular Systems Biology doi: 10.1038/msb4100004 (2005)
 |
|
| Accurate identification of alternatively spliced exons using support vector machine |
| Gideon Dror, Rotem Sorek and Ron Shamir |
Bioinformatics (21) 897-901 (2005)
|
|
| The degenerate primer design problem: Theory and applications |
| C. Linhart and R. Shamir |
Journal of Computational Biology 12 (4) 431-456 (2005)
 |
|
| The Incomplete Perfect Phylogeny Haplotype Problem |
| Gad Kimmel and Ron Shamir |
Journal of Bioinformatics and Computational Biology Vol. 3 No. 2 1-25 (2005)
 |
|
| >Modeling and analysis of heterogeneous regulation in biological
networks |
| I. Gat-Viks, A. Tanay, R. Shamir |
Proc. of the first RECOMB satellite workshop on Regulatory Genomics, E. Eskin and C. Workman (editors), Lecture Notes in Bioinformatics, Vol. 3318 pp. 98-113, Springer, Berlin (2005)
 |
|
| GERBIL: GEnotype Resolution and Block Identification using Likelihood |
| G.Kimmel and R. Shamir |
Proc. National Academy of Science USA 102: 158-162 (2005)
(website and supplementary material) |
|
2004
|
| A fully dynamic algorithms for modular decomposition and representation of cographs |
| R. Shamir and R. Sharan |
Discrete Applied Mathematics, Vol. 136, No. 2-3, Pages 329-340 (2004)
 |
|
| A note on tolerance graph recognition |
| Ryan B. Hayward and Ron Shamir |
Discrete Applied Mathematics, Vol. 143, No. 307-311 (2004)  |
|
| Maximum likelihood resolution of multi-block genotypes |
| G. Kimmel and R. Shamir |
Proc. of RECOMB 2004, pp. 2-9 (2004)
|
|
| Identification of Protein Complexes by Comparative Analysis of Yeast and Bacterial Protein Interaction Data |
| R. Sharan, T. Ideker, B. Kelley, R. Shamir, R. M. Karp |
Proc. of RECOMB 2004, pp. 282-289 (2004)
 |
|
| Identification of Protein Complexes by Comparative Analysis of Yeast and Bacterial Protein Interaction Data |
| R. Sharan, T. Ideker, B. Kelley, R. Shamir, R. M. Karp |
Journal of Computational Biology Volume 12, pp. 835-846, 2005
 |
|
| Multi-level Modeling and Inference of Transcription Regulation |
| A. Tanay and R. Shamir |
Journal of Computational Biology Vol. 11 No. 2-3, pp. 357-376 (2004)
 |
|
| Incomplete Directed Perfect Phylogeny |
| Itsik Pe'er, Tal Pupko, Ron Shamir and Roded Sharan |
SIAM Journal on Computing Vol. 33 No. 3, 590-607 (2004)
|
|
| Cluster Graph Modification Problems |
| Ron Shamir, Roded Sharan and Dekel Tsur |
Discrete Applied Mathematics, Vol. 144, pp. 173-182 (2004)
 |
|
| How prevalent is functional alternative splicing in the human genome? |
| R. Sorek, R. Shamir, G. Ast |
Trends in Genetics 20 (2), 68-71 (2004)
 |
|
| The Canine Olfactory Subgenome |
| Tsviya Olender, Tania Fuchs, Chaim Linhart, Ron Shamir, Mark Adams,Francis Kalush, Miriam Khen and Doron Lancet |
Genomics 83, 361-372 (2004)
 |
|
| PIVOT: Protein Interactions VisualizatiOn Tool |
| Nir Orlev, Ron Shamir and Yosef Shiloh |
Bioinformatics 30 (3), 424-425 (2004)
 |
|
| Revealing modularity and organization in the yeast molecular network by integrated analysis of highly heterogeneous genomewide data |
| A. Tanay, R. Sharan, M. Kupiec, R. Shamir |
Proc. National Academy of Science USA 101 (9) 2981-2986 (March 2004)
(website and supplementary material) |
|
| Computational Problems in Perfect Phylogeny Haplotyping: Xor-Genotypes and Tag SNPs |
| Tamar Barzuza, Jacques S. Beckmann, Ron Shamir and Itsik Peer |
Proc. of CPM 2004, LNCS 3109, pp. 14-31 (2004)
 |
|
| A Global View of the Selection Forces in the Evolution of Yeast Cis-Regulation |
| A. Tanay, I. Gat-Viks, and R. Shamir |
Genome Research 14: 829-834 (2004)
(website and supplementary material) |
|
| A non-EST based method for exon-skipping prediction |
| R. Sorek, R. Shemesh, Y. Cohen, O. Basechess, G. Ast, R. Shamir |
Genome Research 14 pp. 1617-1623 (2004)  |
|
| Reconstructing Chain Functions in Genetic Networks |
| I. Gat-Viks, R. Shamir, R.M. Karp and R. Sharan |
Pacific Symposium on Biocomputing 2004
 |
|
| Modeling and Analysis of Heterogeneous Regulation in Biological Networks |
| I. Gat-Viks, A. Tanay and R. Shamir |
Journal of Computational Biology Vol. 11 No. 6 pp. 1034-1049 (2004)
 |
|
| Towards Optimally Multiplexed Applications of Universal Arrays |
| A. Ben-Dor, T. Hartman, R. M. Karp, B. Schwikowski, R. Sharan and Z. Yakhini |
Journal of Computational Biology 11(2-3), pp. 477-494 (2004)
|
|
| Designing Multi-Route Synthesis in Combinatorial Chemistry |
| A. Akavia, H. Senderowitz, A. Lerner and R. Shamir |
Journal of Combinatorial Chemistry, Vol. 6, No. 4, pp. 540-548 (2004)
 |
|
| Computational Problems in Noisy SNP and Haplotype Analysis: Block Scores, Block Identification and Population Stratification |
| Gad Kimmel, Roded Sharan and Ron Shamir |
INFORMS Journal on Computing, Vol. 16, No. 4, pp. 360-370 (2004)
 |
|
| In silico identification of transcriptional regulators associated with c-Myc |
| R. Elkon, K. Zeller, C. Linhart, C. Dang, R. Shamir and Y. Shiloh |
Nucleic Acid Research Vol. 32 No. 17, pp. 4955-4961 (2004)
 |
|
2003
|
| The Restriction Scaffold Problem |
| A. Ben-Dor, R. M. Karp, B. Schwikowski, R. Shamir |
Computational Biology
Vol. 10 No. 3-4, pp. 385-398 (2003)
 |
|
| Handling Long Targets and Errors in Sequencing by Hybridization |
| E. Halperin, S. Halperin, T. Hartman and R. Shamir |
Journal of Computational Biology Vol. 10 No. 3-4, pp. 483-498 (2003)
|
|
| Two notes on genome rearrangements |
| Michal Ozery-Flato and Ron Shamir |
Journal of Bioinformatics and Computational Biology, Vol. 1, No. 1, pp. 71-94 (2003)
|
|
| Genome-Wide In Silico Identification of Transcriptional Regulators Controlling the Cell Cycle in Human Cells |
| Ran Elkon, Chaim Linhart, Roded Sharan, Ron Shamir, and Yosef Shiloh |
Genome Research Vol. 13(5), pp. 773-780, (2003)
(website and supplementary material) |
|
| Identifying Blocks and Sub-Populations in Noisy SNP Data |
| Gad Kimmel, Roded Sharan and Ron Shamir |
Proc. of WABI 2003, pp. 303-319 (2003)
|
|
| Chain functions and scoring functions in genetic networks |
| Irit Gat-Viks and Ron Shamir |
Bioinformatics, Vol. 19, Supplement 1, pp. i108-i117 (2003)
 |
|
| Simpler 1.5-Approximation Algorithm for Sorting by Transpositions |
| Tzvika Hartman |
Proc. of CPM 2003, pp. 156-169
 |
|
| Towards Optimally Multiplexed Applications of Universal DNA Tag Systems |
| Amir Ben-Dor, Tzvika Hartman, Benno Schwikowski , Roded Sharan , and Zohar Yakhini |
Proc. of RECOMB 2003, pp. 48-56
 |
|
| Detecting Excess Radical Replacements in Phylogenetic Trees |
| T. Pupko, R. Sharan, M. Hasegawa, R. Shamir and D. Graur |
Gene 319, pp. 127-135, 2003
 |
|
| Advanced Computational Techniques for Resequencing DNA with Polymerase Signaling Assay Arrays |
| Itsik Pe'er, Naama Arbili, Yi Liu, Colby Enck, Craig Gelfand, Ron Shamir |
Nucleic Acids Research 31(19):5667-75 (2003)
 |
|
| CLICK and EXPANDER: A System for Clustering and Visualizing Gene Expression Data |
| Roded Sharan, Adi Maron-Katz and Ron Shamir |
Bioinformatics, Vol. 19, No. 14, pp. 1787-1799 (2003)
(website) |
|
| Improved Algorithms for the Random Cluster Graph Model |
| R. Shamir and D. Tsur |
Lecture Notes In Computer Science Vol. 2368
|
|
| Scoring clustering solutions by their biological relevance |
| I. Gat-Viks, R. Sharan, R. Shamir |
Bioinformatics 19: 2381-2389 (2003)
 |
|
| Modeling transcription programs: inferring binding site activity and dose-response model optimization |
| A. Tanay and R. Shamir |
Proc. of RECOMB 2003, pp. 301-310
 |
|
2002
|
| On the Complexity of Positional Sequencing by Hybridization |
| Ben-Dor, I. Pe'er, R. Shamir and R. Sharan |
Journal of Computational Biology Vol. 8 No. 4, pp. 361-371 (2002)
 |
|
| Algorithmic Approaches to Clustering Gene Expression Data |
| Ron Shamir and Roded Sharan |
Current Topics in Computational Molecular Biology, T.Jiang, T. Smith, Y. Xu, M. Q. Zhang (editors), pp. 269-300, MIT Press, 2002
|
|
| Cluster Analysis and its Applications to Gene Expression Data |
| Roded Sharan, Rani Elkon and Ron Shamir |
Ernst Schering workshop on Bioinformatics and Genome Analysis, pp. 83-108, Springer Verlag, Berlin 2002
 |
|
| The Restriction Scaffold Problem |
| A. Ben-Dor, R. M. Karp, B. Schwikowski, R. Shamir |
Proc. of RECOMB 2002, (extended abstract)
 |
|
| Discovering Statistically Significant Biclusters in Gene Expression Data |
| A. Tanay, R. Sharan, R. Shamir |
Proc. of ISMB 2002; Bioinformatics Vol. 18 Suppl. 1 S136-S144
 |
|
| Handling Long Targets and Errors in Sequencing by Hybridization |
| E. Halperin, S. Halperin, T. Hartman and R. Shamir |
Proc. of RECOMB 2002, pp. 176-185 (extended abstract)
 |
|
| The Degenerate Primer Design Problem |
| C. Linhart, R. Shamir |
Proc. of ISMB 2002; Bioinformatics, Vol. 18, Suppl. 1 S172-S180
(website) |
|
| On the Properties of Sequences of Reversals that Sort a Signed Permutation |
| Anne Bergeron, Cedric Chauve, Tzvika Hartman and Karine St-Onge |
Proc. of JOBIM 2002, pp. 99-108
 |
|
| DEFOG: A Practical Scheme for Deciphering Families of Genes |
| Tania Fuchs, Barbora Malecova, Chaim Linhart, Roded Sharan, Miriam Khen, Ralf Herwig, Dmitry Shmulevich, Rani Elkon, Matthias Steinfath, John K. O'Brien, Uwe Radelof, Hans Lehrach, Doron Lancet, and Ron Shamir |
Genomics Vol. 80, No. 3, 295-302 (2002)
 |
|
| A computational method for resequencing long DNA targets by universal oligonucleotide arrays |
| I. Pe'er, N. Arbili and R. Shamir |
Proc. National Academy of Science USA Vol. 99 pp. 15497-15500 (2002)
 |
|
2001
|
| Complexity Classification of Some Edge Modification Problems |
| A. Natanzon, R. Shamir and R.Sharan |
Discrete Applied Mathematics, Vol. 113, No. 1, pp. 109-128 (2001)
 |
|
| A Fully Dynamic Algorithm for Recognizing and Representing Proper Interval Graphs |
| Pavol Hell, Ron Shamir and Roded Sharan |
SIAM Journal on Computing Vol. 31, No. 1, pp. 289-305 (2001)
 |
|
| Large Scale Sequencing By Hybridization |
| Ron Shamir and Dekel Tsur |
Proc. of RECOMB 2001, pp. 267-279, ACM Press, New York, NY (2001)
 |
|
| Computational Expansion of Genetic Networks |
| A. Tanay and Ron Shamir |
Proc. of ISMB 2001; Bioinformatics Vol. 17, Supplement 1, pp. S270-S278 (2001)
 |
|
| A Chemical Distance Based Test for Positive Darwinian Selection |
| T. Pupko, R. Sharan, M. Hasegawa, R. Shamir and D. Graur |
Proc. of WABI 2001 (extended abstract)
 |
|
2000
|
| Algorithms for Optical Mapping |
| R. M. Karp, R. Shamir |
Journal of Computational Biology Vol. 7, No. 1/2, pp. 303-316 (2000)
 |
|
| A Polynomial Approximation Algorithm for the Minimum Fill-In Problem |
| A. Natanzon, R. Shamir and R.Sharan |
SIAM Journal on Computing, Vol. 30, No. 4, pp. 1067-1079 (2000)
 |
|
| An Algorithm for Clustering cDNAs for Gene
Expression Analysis Using Short Oligonucleotide Fingerprints |
| E. Hartuv, A. Schmitt, J. Lange, S. Meier-Ewert, H. Lehrach and R. Shamir |
Genomics
, Vol. 66, No. 3, pp. 249-256 (2000)
 |
|
| A Clustering Algorithm based on Graph Connectivity |
| E. Hartuv, R. Shamir |
Information Processing Letters, Vol. 76, pp. 175-181 (2000)
 |
|
| Fast Algorithm for Reconstruction of Ancestral Amino-Acid Sequences |
| Tal Pupko, Itsik Pe'er, Ron Shamir and Dan Graur |
Molecular Biology and Evolution, Vol. 17, No. 6, pp. 890-896 (2000)
 |
|
| An Algorithm Combining Discrete and Continuous Methods for Optical Mapping |
| Richard M. Karp, Itsik Pe'er, Ron Shamir |
J. Computational Biology, Vol. 7, No. 1/2, pp. 303-316 (2000)
 |
|
| Approximation Algorithms for the Median Problem in the Breakpoint Model |
| Itsik Pe'er and Ron Shamir |
Comparative Genomics: Empirical and Analytical Approaches to Gene Order Dynamics, Map Alignment and the Evolution of Gene Families (D. Sankoff and J. H. Nadeau, editors), Kluwer Academic Press (Dordrecht), 2000
 |
|
| CLICK: A Clustering Algorithm with Applications to Gene Expression Analysis |
| Roded Sharan and Ron Shamir |
Currents in Compuational Molecular Biology, pp. 6-7, S. Miyano, R. Shamir and T. Takagi (editors) Universal Academy Press, 2000 (short summary)
; Proc. of ISMB 2000, pp. 307-316, AAAI Press, Menlo Park, CA (2000) (Expander Home page) |
|
| Spectrum Alignment: Efficient Resequencing by Hybridization |
| Itsik Pe'er and Ron Shamir |
Proc. of ISMB 2000, pp. 260-268, AAAI Press, Menlo Park, CA (2000)
 |
|
| Incomplete Directed Perfect Phylogeny |
| Itsik Pe'er, Ron Shamir and Roded Sharan |
Proc. of CPM 2000, pp. 143-153
 |
|
1999
|
| Bounded Degree Interval Sandwich Problems |
| Haim Kaplan and Ron Shamir |
Algorithmica, Vol. 24, No. 2, pp. 96-104 (1999)
 |
|
| Tractability of parameterized completion problems on chordal, strongly chordal and proper interval graphs |
| Haim Kaplan, Ron Shamir and Robert E. Tarjan |
SIAM Journal of Computing, Vol. 28, No. 5, pp. 1906-1922 (1999)
 |
|
| Faster and Simpler Algorithm for Sorting Signed Permutations by Reversals |
| Haim Kaplan, Ron Shamir and Robert E. Tarjan |
SIAM Journal on Computing, Vol. 29, No. 3, pp. 880-892 (1999)
 |
|
| Faster Subtree Isomorphism |
| Ron Shamir, Dekel Tzur |
Journal of Algorithms, Vol. 33, pp. 267-280 (1999)
 |
|
| Construction of Physical Maps From Oligonucleotide Fingerprints Data |
| G. Mayraz, R. Shamir |
Journal of Computational Biology, Vol. 6, No. 2, pp. 237-252 (1999)
 |
|
| An Algorithm for Clustering cDNAs for Gene Expression Analysis Using Short Oligonucleotide Fingerprints |
| E. Hartuv, A. Schmitt, J. Lange, S. Meier-Ewert, H. Lehrach and R. Shamir |
Proc. of RECOMB 1999, pp. 188-197 (extended abstract)
 |
|
| Clustering Gene Expression Patterns |
| A. Ben-Dor, R. Shamir, Z. Yakhini |
Journal of Computational Biology, Vol. 6, No. 3/4, pp. 281-297 (1999)
 |
|
| On the Complexity of Positional Sequencing by Hybridization |
| Ben-Dor, I. Pe'er, R. Shamir and R. Sharan |
Proc. of CPM 1999, (LNCS 1645) pp. 88-100 (extended abstract)
 |
|
| An Algorithm Combining Discrete and Continuous Methods for Optical Mapping |
| Richard M. Karp, Itsik Pe'er, Ron Shamir |
Proc. of ISMB 1999, pp. 159-168 (extended abstract)
 |
|
| Perfect Completion and Deletion in Random Graphs |
| Assaf Natanzon, Ron Shamir |
Technical Report, 1999
 |
|
| Optimizing the BAC-End Strategy for Sequencing the Human Genome |
| Kichard M. Karp, Ron Shamir |
Technical Report, April 1999
 |
|
| A Fully Dynamic Algorithm for Recognizing and Representing Proper Interval Graphs |
| Pavol Hell, Ron Shamir and Roded Sharan |
Proc. of ESA 1999, pp. 527-539, LNCS 1643
 |
|
1998 and before
|
| Algorithms for Optical Mapping |
| R. M. Karp, R. Shamir |
Proc. of RECOMB 1998, pp. 117-124 (extended abstract)
 |
|
| A Polynomial Approximation Algorithm for the Minimum Fill-In Problem |
| A. Natanzon, R. Shamir and R.Sharan |
Proc. of STOC 1998, pp. 41-47
 |
|
| The maximum subforest problem: Approximation and exact algorithms |
| Ron Shamir, Dekel Tzur |
Proc. of SODA 1998, pp. 394-399
 |
|
| Faster and Simpler Algorithm for Sorting Signed Permutations by Reversals |
| Haim Kaplan, Ron Shamir and Robert E. Tarjan |
Proc. of SODA 1997, pp. 344-351
; Also Proc. of RECOMB 1997, pp. 163 |
|
| Realizing interval graphs with size and distance constraints |
| Itsik Pe'er and Ron Shamir |
SIAM Journal of Discrete Mathematics, Vol. 10, No. 4, pp. 662-687 (1997)
|
|
| Satisfiability Problems on Intervals and Unit Intervals |
| Itsik Pe'er and Ron Shamir |
Theoretical Computer Science, Vol. 175, No. 2, pp. 349-372 (1997)
|
|
| Pathwidth, Bandwidth and Completion Problems to Proper Interval Graphs with Small Cliques |
| Haim Kaplan, Ron Shamir |
SIAM J. Computing, Vol. 25, No. 3, pp. 540-561 (1996)
 |
|
| Physical Maps and Interval Sandwich Problems: Bounded Degrees Help |
| Haim Kaplan and Ron Shamir |
Proc. of ISTCS 1996, IEEE Computer Science Press, pp. 195-201
 |
|
| Interval Graphs with Side (and Size) Constraints |
| Itsik Pe'er and Ron Shamir |
Proc. of the Third European Symposium on Algorithms (ESA 95), Springer, Berlin, pp. 142-154
 |
|
| Four Strikes Against Physical Mapping of DNA |
| Paul W. Goldberg, Martin C. Golumbic, Haim Kaplan and Ron Shamir |
Journal of Computational Biology, Vol. 2, No. 1, pp. 139-152 (1995)
 |
|
| Algorithms and Complexity of Sandwich Problems in Graphs |
| Martin Golumbic Haim Kaplan, Ron Shamir |
Proc. of WG 1993, pp. 57-69, LNCS 790, Springer, Berlin, 1994
 |
|
| Tractability of parameterized completion problems on chordal and interval graphs: Minimum Fill-in and Physical Mapping |
| Haim Kaplan, Ron Shamir, Robert E. Tarjan |
Proc. of FOCS 1994, pp. 780-791
 |
|
| Complexity and algorithms for reasoning about time: a graph-theoretic approach |
| Martin Golumbic, Ron Shamir |
JACM, Vol. 40, pp. 1108-1133 (1993)
 |
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