ASTHMA Down regulated
IDSymbolDescriptionAliases
3146HMGB1high-mobility group box 1DKFZp686A04236,HMG1,HMG3,SBP-1
10542HBXIPhepatitis B virus x interacting proteinMGC71071,XIP
2915GRM5glutamate receptor, metabotropic 5GPRC1E,MGLUR5,MGLUR5A,MGLUR5B,mGlu5
6670SP3Sp3 transcription factorDKFZp686O1631,SPR-2
3480IGF1Rinsulin-like growth factor 1 receptorCD221,IGFIR,JTK13,MGC142170,MGC142172,MGC18216
11214AKAP13A kinase (PRKA) anchor protein 13AKAP-Lbc,BRX,FLJ11952,FLJ43341,HA-3,Ht31,LBC,PROTO-LB,PROTO-LBC,c-lbc
23097CDC2L6cell division cycle 2-like 6 (CDK8-like)CDK11,KIAA1028,bA346C16.3
8085MLL2myeloid/lymphoid or mixed-lineage leukemia 2AAD10,ALR
29899GPSM2G-protein signalling modulator 2 (AGS3-like, C. elegans)LGN,Pins
7052TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)TG2,TGC
2917GRM7glutamate receptor, metabotropic 7FLJ40498,GLUR7,GPRC1G,MGLUR7,mGlu7
9063PIAS2protein inhibitor of activated STAT, 2MGC102682,MIZ1,PIASX-ALPHA,PIASX-BETA,SIZ2,ZMIZ4,miz
26135SERBP1SERPINE1 mRNA binding protein 1CGI-55,CHD3IP,DKFZp564M2423,FLJ90489,HABP4L,PAI-RBP1,PAIRBP1
4130MAP1Amicrotubule-associated protein 1AMAP1L,MTAP1A
3670ISL1ISL1 transcription factor, LIM/homeodomain, (islet-1)Isl-1
5470PPEF2protein phosphatase, EF-hand calcium binding domain 2-
57492ARID1BAT rich interactive domain 1B (SWI1-like)6A3-5,BAF250b,BRIGHT,DAN15,ELD/OSA1,KIAA1235,p250R
150684COMMD1copper metabolism (Murr1) domain containing 1C2orf5,MGC27155,MURR1
8428STK24serine/threonine kinase 24 (STE20 homolog, yeast)MST-3,MST3,MST3B,STK3
80306MED28mediator of RNA polymerase II transcription, subunit 28 homolog (S. cerevisiae)1500003D12Rik,DKFZP434N185,EG1,magicin
10521DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 17DKFZp761H2016,P72,RH70
405ARNTaryl hydrocarbon receptor nuclear translocatorHIF-1beta,HIF1B,HIF1BETA,TANGO
4005LMO2LIM domain only 2 (rhombotin-like 1)RBTN2,RBTNL1,RHOM2,TTG2
5296PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)P85B,p85-BETA
9223MAGI1membrane associated guanylate kinase, WW and PDZ domain containing 1AIP3,BAIAP1,BAP1,MAGI-1,TNRC19,WWP3
9611NCOR1nuclear receptor co-repressor 1KIAA1047,MGC104216,N-CoR,TRAC1,hCIT529I10,hN-CoR
8452CUL3cullin 3-
961CD47CD47 moleculeIAP,MER6,OA3
659BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)BMPR-II,BMPR3,BMR2,BRK-3,T-ALK
2643GCH1GTP cyclohydrolase 1 (dopa-responsive dystonia)DYT5,GCH,GTP-CH-1,GTPCH1
3717JAK2Janus kinase 2 (a protein tyrosine kinase)-
23421ITGB3BPintegrin beta 3 binding protein (beta3-endonexin)CENP-R,CENPR,HSU37139,NRIF3,TAP20
4082MARCKSmyristoylated alanine-rich protein kinase C substrate80K-L,FLJ14368,FLJ90045,MACS,MRACKS,PKCSL,PRKCSL
2034EPAS1endothelial PAS domain protein 1HIF2A,HLF,MOP2,PASD2
55922NKRFNF-kappaB repressing factorITBA4,NRF
800CALD1caldesmon 1CDM,H-CAD,L-CAD,MGC21352,NAG22
5747PTK2PTK2 protein tyrosine kinase 2FADK,FAK,FAK1,pp125FAK
1021CDK6cyclin-dependent kinase 6MGC59692,PLSTIRE
8648NCOA1nuclear receptor coactivator 1F-SRC-1,MGC129719,MGC129720,NCoA-1,RIP160,SRC1
9584RBM39RNA binding motif protein 39CAPER,CAPERalpha,CC1.3,DKFZp781C0423,FLJ44170,HCC1,RNPC2
9282CRSP2cofactor required for Sp1 transcriptional activation, subunit 2, 150kDaCRSP150,CSRP,CXorf4,DRIP150,EXLM1,MED14,MGC104513,RGR1,TRAP170
55062WIPI1WD repeat domain, phosphoinositide interacting 1Atg18,FLJ10055,WIPI49
9439CRSP3cofactor required for Sp1 transcriptional activation, subunit 3, 130kDaCRSP130,CRSP133,DKFZp434H0117,DRIP130,MED23,SUR2
3688ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)CD29,FNRB,GPIIA,MDF2,MSK12,VLAB
30011SH3KBP1SH3-domain kinase binding protein 1CIN85,GIG10,MIG18
4869NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)B23,MGC104254,NPM
6498SKILSKI-like oncogeneSNO,SnoA,SnoN
56252YLPM1YLP motif containing 1C14orf170,ZAP,ZAP3
79718TBL1XR1transducin (beta)-like 1X-linked receptor 1C21,DC42,FLJ12894,IRA1,TBLR1
5927JARID1Ajumonji, AT rich interactive domain 1ARBBP2,RBP2
6597SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4BAF190,BRG1,FLJ39786,SNF2,SNF2-BETA,SNF2L4,SNF2LB,SWI2,hSNF2b
6881TAF10TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDaTAF2A,TAF2H,TAFII30
10048RANBP9RAN binding protein 9RANBPM
5599MAPK8mitogen-activated protein kinase 8JNK,JNK1,JNK1A2,JNK21B1/2,PRKM8,SAPK1
3691ITGB4integrin, beta 4CD104
5903RANBP2RAN binding protein 2NUP358,TRP1,TRP2
1398CRKv-crk sarcoma virus CT10 oncogene homolog (avian)CRKII
80854SETD7SET domain containing (lysine methyltransferase) 7FLJ21193,KIAA1717,SET7,SET7/9,SET9
5928RBBP4retinoblastoma binding protein 4NURF55,RBAP48
2969GTF2Igeneral transcription factor II, iBAP-135,BAP135,BTKAP1,DIWS,IB291,SPIN,TFII-I,WBS,WBSCR6
5458POU4F2POU domain, class 4, transcription factor 2BRN3.2,BRN3B,Brn-3b
5906RAP1ARAP1A, member of RAS oncogene familyKREV-1,KREV1,RAP1,SMGP21
8650NUMBnumb homolog (Drosophila)S171
59340HRH4histamine receptor H4AXOR35,BG26,GPCR105,GPRv53,H4,H4R,HH4R,MGC133027
57062DDX24DEAD (Asp-Glu-Ala-Asp) box polypeptide 24-
4582MUC1mucin 1, cell surface associatedCD227,EMA,H23AG,MAM6,PEM,PEMT,PUM
3170FOXA2forkhead box A2HNF3B,MGC19807,TCF3B
688KLF5Kruppel-like factor 5 (intestinal)BTEB2,CKLF,IKLF
7494XBP1X-box binding protein 1TREB5,XBP2
4690NCK1NCK adaptor protein 1MGC12668,NCK,NCKalpha
203068TUBBtubulin, betaM40,MGC117247,MGC16435,OK/SW-cl.56,TUBB1,TUBB5
7936RDBPRD RNA binding proteinD6S45,NELF-E,RD,RDP
1385CREB1cAMP responsive element binding protein 1CREB,MGC9284
5929RBBP5retinoblastoma binding protein 5RBQ3,SWD1
10728PTGES3prostaglandin E synthase 3 (cytosolic)P23,TEBP
6925TCF4transcription factor 4E2-2,ITF2,MGC149723,MGC149724,SEF2,SEF2-1,SEF2-1A,SEF2-1B
55660PRPF40APRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)FBP-11,FBP11,FLAF1,FLJ20585,FNBP3,HIP10,HYPA,NY-REN-6
7852CXCR4chemokine (C-X-C motif) receptor 4CD184,D2S201E,FB22,HM89,HSY3RR,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM
23032USP33ubiquitin specific peptidase 33KIAA1097,MGC16868,VDU1
9444QKIquaking homolog, KH domain RNA binding (mouse)DKFZp586I0923,Hqk,QK,QK3
4193MDM2Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)HDMX,MGC71221,hdm2
3716JAK1Janus kinase 1 (a protein tyrosine kinase)JAK1A,JAK1B
6801STRNstriatin, calmodulin binding proteinMGC125642,SG2NA
8481OFD1oral-facial-digital syndrome 171-7A,CXorf5,MGC117039,MGC117040,SGBS2
3667IRS1insulin receptor substrate 1HIRS-1
9139CBFA2T2core-binding factor, runt domain, alpha subunit 2; translocated to, 2DKFZp313F2116,EHT,MTGR1,ZMYND3
3643INSRinsulin receptorCD220,HHF5
2355FOSL2FOS-like antigen 2FLJ23306,FRA2
595CCND1cyclin D1BCL1,D11S287E,PRAD1,U21B31
8554PIAS1protein inhibitor of activated STAT, 1DDXBP1,GBP,GU/RH-II,MGC141878,MGC141879,ZMIZ3
10291SF3A1splicing factor 3a, subunit 1, 120kDaPRP21,PRPF21,SAP114,SF3A120
4194MDM4Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse)DKFZp781B1423,MDMX,MGC132766,MRP1
23054NCOA6nuclear receptor coactivator 6AIB3,ANTP,ASC2,HOX1.1,HOXA7,KIAA0181,NRC,PRIP,RAP250,TRBP
23365ARHGEF12Rho guanine nucleotide exchange factor (GEF) 12DKFZp686O2372,KIAA0382,LARG,PRO2792
3092HIP1huntingtin interacting protein 1ILWEQ,MGC126506
29110TBK1TANK-binding kinase 1FLJ11330,NAK,T2K
3276PRMT1protein arginine methyltransferase 1ANM1,HCP1,HRMT1L2,IR1B4
81857MED25mediator of RNA polymerase II transcription, subunit 25 homolog (S. cerevisiae)ACID1,ARC92,DKFZp434K0512,MGC70671,P78,TCBAP0758
3693ITGB5integrin, beta 5FLJ26658
4790NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)DKFZp686C01211,EBP-1,KBF1,MGC54151,NF-kappa-B,NFKB-p105,NFKB-p50
805CALM2calmodulin 2 (phosphorylase kinase, delta)CAMII,PHKD,PHKD2
2113ETS1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)ETS-1,EWSR2,FLJ10768
5934RBL2retinoblastoma-like 2 (p130)FLJ26459,P130,Rb2
55388MCM10MCM10 minichromosome maintenance deficient 10 (S. cerevisiae)CNA43,MGC126776,PRO2249
6002RGS12regulator of G-protein signalling 12DKFZp761K1617,DKFZp761K1817
5469PPARBPPPAR binding proteinCRSP1,CRSP200,DRIP205,DRIP230,MED1,MGC71488,PBP,PPARGBP,RB18A,TRAP220,TRIP2
23411SIRT1sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)SIR2L1
6197RPS6KA3ribosomal protein S6 kinase, 90kDa, polypeptide 3CLS,HU-3,ISPK-1,MAPKAPK1B,MRX19,RSK,RSK2,S6K-alpha3,p90-RSK2,pp90RSK2
7026NR2F2nuclear receptor subfamily 2, group F, member 2ARP1,COUP-TFII,COUPTFB,MGC117452,SVP40,TFCOUP2
2099ESR1estrogen receptor 1DKFZp686N23123,ER,ESR,ESRA,Era,NR3A1
3105HLA-Amajor histocompatibility complex, class I, A-
51199NINninein (GSK3B interacting protein)KIAA1565
64210MMS19LMMS19-like (MET18 homolog, S. cerevisiae)MET18,MGC99604,MMS19,hMMS19
5515PPP2CAprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoformPP2Ac,PP2CA,RP-C
54969C4orf27chromosome 4 open reading frame 27FLJ20534
8660IRS2insulin receptor substrate 2-
6294SAFBscaffold attachment factor BDKFZp779C1727,HAP,HET,SAFB1
9391CIAO1cytosolic iron-sulfur protein assembly 1 homolog (S. cerevisiae)CIA1,WDR39
5457POU4F1POU domain, class 4, transcription factor 1BRN3A,FLJ13449,Oct-T1,RDC-1
6760SS18synovial sarcoma translocation, chromosome 18MGC116875,SSXT,SYT
23493HEY2hairy/enhancer-of-split related with YRPW motif 2CHF1,GRL,HERP1,HESR2,HRT2,MGC10720
2309FOXO3Aforkhead box O3AAF6q21,DKFZp781A0677,FKHRL1,FKHRL1P2,MGC12739,MGC31925
7323UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)E2(17)KB3,MGC43926,MGC5416,UBC4/5,UBCH5C
8721EDF1endothelial differentiation-related factor 1EDF-1,MBF1,MGC9058
6772STAT1signal transducer and activator of transcription 1, 91kDaDKFZp686B04100,ISGF-3,STAT91
51003MED31mediator of RNA polymerase II transcription, subunit 31 homolog (S. cerevisiae)3110004H13Rik,CGI-125,FLJ27436,Soh1
6654SOS1son of sevenless homolog 1 (Drosophila)GF1,GGF1,GINGF,HGF,NS4
57562KIAA1377KIAA1377-
6096RORBRAR-related orphan receptor BNR1F2,ROR-BETA,RZRB,bA133M9.1
890CCNA2cyclin A2CCN1,CCNA
1739DLG1discs, large homolog 1 (Drosophila)DKFZp761P0818,DLGH1,SAP97,dJ1061C18.1.1,hdlg
51678MPP6membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)PALS2,VAM-1,VAM1,p55T
217ALDH2aldehyde dehydrogenase 2 family (mitochondrial)ALDH-E2,ALDHI,ALDM,MGC1806
2770GNAI1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1Gi
2064ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)HER-2,HER-2/neu,HER2,NEU,NGL,TKR1,c-erb B2
3726JUNBjun B proto-oncogene-
54014BRWD1bromodomain and WD repeat domain containing 1C21orf107,FLJ43918,N143,WDR9
5966RELv-rel reticuloendotheliosis viral oncogene homolog (avian)C-Rel
3516RBPJrecombination signal binding protein for immunoglobulin kappa J regionCBF1,IGKJRB,IGKJRB1,KBF2,MGC61669,RBP-J,RBPJK,RBPSUH,SUH,csl