| ID | Symbol | Description | Aliases |
| YLR418C | CDC73 | Substituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p, distinct from Srb-containing Pol II complexes; required for expression of certain genes, modification of some histones, and telomere maintenance | | |
| YPL138C | SPP1 | Subunit of COMPASS (Set1C), a complex which methylates histone H3 on lysine 4 and is required in telomeric transcriptional silencing; PHD finger domain protein similar to human CGBP, an unmethylated CpG binding protein | CPS40, SAF41 | |
| YOR123C | LEO1 | Component of the Paf1 complex, which associates with RNA polymerase II and is involved in histone methylation | | |
| YGL244W | RTF1 | Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly regulates DNA-binding properties of Spt15p and relative activities of different TATA elements; involved in telomere maintenance | CSL3 | |
| YAR003W | SWD1 | Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7 | CPS50, FUN16, SAF49 | |
| YBR175W | SWD3 | Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5 | CPS30, SAF35 | |