| ID | Symbol | Description | Aliases |
| YPL055C | LGE1 | Protein of unknown function; null mutant forms abnormally large cells | | |
| YDL074C | BRE1 | E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, recruitment of Rad6p to promoter chromatin and subsequent methylation of histone H3 (on L4 and L79), contains RING finger domain | | |
| YBR097W | VPS15 | Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; also detected in mitochondria | GRD8, VAC4, VPL19 | |
| YLR240W | VPS34 | Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; similar to p110 subunit of mammalian PI 3-kinase | END12, PEP15, VPL7, VPT29 | |